RESUMO
Abstract Introduction: Cancer of the oral cavity and oropharynx presents aggressive behavior and its diagnosis is, in most cases, performed in advanced stages. Total glossectomy is a therapeutic option in locally advanced cancer, and the only one in the recurrent or residual disease, after chemoradiotherapy. Objective: To evaluate the clinical-epidemiological profile, postoperative complications, survival rates and functional aspects of patients with oral cavity and oropharynx cancer after total glossectomy. Methods: It was a retrospective study where 22 patients were included with oral cavity and oropharyngeal cancer after total glossectomy at the Hospital Regional do Vale do Paraíba, em Taubaté, São Paulo. Results: All patients were male, with a median age of 57 years, most of tumors are located in the tongue and floor of the mouth and classified as stage IVa. Total glossectomy as initial treatment was performed in 18 and as salvage in four patients. The major pectoralis myocutaneous flap was used for reconstruction in all cases. The main postoperative complication was wound infection and salivary fistula. Conclusion: Overall survival was 19% and cancer-specific survival was 30.8% in five years. Eight patients were rehabilitated for exclusive oral feeding without the dependence tracheostomy and enteral tube, all with an overall survival greater than 15 months.
Resumo Introdução: O câncer da cavidade oral e da orofaringe apresenta comportamento agressivo e seu diagnóstico é, na maioria dos casos, realizado em fases avançadas. A glossectomia total é uma opção terapêutica no câncer localmente avançado e a única no resgate de pacientes com doença residual ou recorrente, após a quimiorradioterapia. Objetivo: Avaliar o perfil clínico-epidemiológico, as complicações pós-operatórias, as taxas de sobrevida e os aspectos funcionais de pacientes com câncer da cavidade oral e da orofaringe submetidos à glossectomia total. Método: Estudo retrospectivo em que foram incluídos 22 pacientes com câncer de cavidade oral e orofaringe submetidos à glossectomia total no Hospital Regional do Vale do Paraíba, em Taubaté, São Paulo. Resultados: Todos os pacientes eram do gênero masculino, com mediana de 57 anos, com tumores principalmente na língua e no assoalho da boca e classificados, em sua maioria, como estádio clínico IVa. A glossectomia total como tratamento inicial foi realizada em 18 e como resgate em quatro pacientes. O retalho miocutâneo peitoral maior foi utilizado para a reconstrução em todos os casos. A principal complicação pós-operatória foi a infecção da ferida operatória e a fístula salivar. Conclusão: A sobrevida global foi de 19% e a específica por câncer de 30,8% em cinco anos. Oito pacientes foram reabilitados para alimentação oral exclusiva sem a dependência de traqueostomia e ou de dieta enteral, todos com sobrevida global maior do que 15 meses.
Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias Orofaríngeas , Músculos Peitorais , Neoplasias da Língua , Traqueostomia , Estudos Retrospectivos , Procedimentos de Cirurgia Plástica , GlossectomiaRESUMO
INTRODUCTION: Cancer of the oral cavity and oropharynx presents aggressive behavior and its diagnosis is, in most cases, performed in advanced stages. Total glossectomy is a therapeutic option in locally advanced cancer, and the only one in the recurrent or residual disease, after chemoradiotherapy. OBJECTIVE: To evaluate the clinical-epidemiological profile, postoperative complications, survival rates and functional aspects of patients with oral cavity and oropharynx cancer after total glossectomy. METHODS: It was a retrospective study where 22 patients were included with oral cavity and oropharyngeal cancer after total glossectomy at the Hospital Regional do Vale do Paraíba, em Taubaté, São Paulo. RESULTS: All patients were male, with a median age of 57 years, most of tumors are located in the tongue and floor of the mouth and classified as stage IVa. Total glossectomy as initial treatment was performed in 18 and as salvage in four patients. The major pectoralis myocutaneous flap was used for reconstruction in all cases. The main postoperative complication was wound infection and salivary fistula. CONCLUSION: Overall survival was 19% and cancer-specific survival was 30.8% in five years. Eight patients were rehabilitated for exclusive oral feeding without the dependence tracheostomy and enteral tube, all with an overall survival greater than 15 months.
Assuntos
Neoplasias Orofaríngeas , Glossectomia , Humanos , Masculino , Pessoa de Meia-Idade , Músculos Peitorais , Procedimentos de Cirurgia Plástica , Estudos Retrospectivos , Neoplasias da Língua , TraqueostomiaRESUMO
A reabilitação do membro superior do paciente com sequelas de acidente vascular encefálico é um dos desafios de maior complexidade para o fisioterapeuta. O objetivo deste estudo foi verificar o uso da Terapia de Contenção Induzida (técnica recente) isoladamente na melhora funcional do membro superior parético em pacientes pós-acidente vascular encefálico a partir de uma revisão sistemática sem metanálise das bases de dados PubMed,LILACS e SciELO, seguindo os critérios de inclusão: ano de publicação entre 2010 e 2015, estudos clínicos controlados e randomizados que avaliaram a funcionalidade do membro superior hemiparético, e estudos que utilizaram somente a Terapia de Contensão Induzida como técnica de tratamento no mesmo grupo estudado. Foram critérios de exclusão relativos à Terapia de Contensão Induzida: associada a outras técnicas de reabilitação no mesmo grupo estudado, modificada, realizada para fins que não para o membro superior parético, e realizada em crianças e adolescentes ou em pacientes com paralisia cerebral. Foram encontrados 352 artigos. Seis artigos se enquadraram nos critérios de inclusão e exclusão. Dos seis artigos, três apresentaram a comparação da Terapia de Contensão Induzida com outras técnicas, como Bobath, estimulação magnética transcraniana repetitiva de baixa frequência, terapia ocupacional e terapia intensiva bilateral. Dois artigos verificaram a Terapia de Contensão Induzida precoce e tardiamente; somente um avaliou o fluxo sanguíneo do hemisfério afetado durante tarefas motoras com e sem restrição. Conclui-se que a Terapia de Contensão Induzida utilizada precocemente oferece resultados satisfatórios quando comparados com técnicas mais tradicionais.
Upper limb rehabilitation in patients with stroke sequelae is one of the most complex challenges to the physiotherapist. The aim of this study was to investigate the use of constraint-Induced movement therapy (recent technique) alone in functional improvement of the paretic upper limb in post-stroke patients through a systematic review with no metanalysis of databases of PubMed, LILACS and SciELO. The inclusion criteria were: year of publication between 2010 and 2015; controlled and randomized clinical studies that evaluated the functionality of hemiparetic upper limb, and controlled and randomized clinical studies evaluating only the Constraint-induced Movement Therapy as a treatment technique in the same study group.Exclusion criteria related to the Constraint-induced Movement Therapy were: associated with other rehabilitation techniques in the same study group, modified, carried out for purposes other than for the paretic upper limb, and performed in children and teenagers or in patients with cerebral palsy. We found 352 articles. Six articles met the inclusion and exclusion criteria. Of the six articles, three had a comparison of Constraint-induced movement therapy with other techniques, such as Bobath,low-frequency repetitive transcranial magnetic stimulation,occupational therapy, and bilateral intensive therapy. Two articles observed early and late Constraint-induced Movement Therapy; only one evaluated the blood flow of the affected hemisphere during motor tasks with and without constraint. It was concluded that the Constraint-induced Movement Therapy use provides satisfactory results when compared with more traditional techniques
Assuntos
Humanos , Modalidades de Fisioterapia/instrumentação , Contenções/estatística & dados numéricos , Acidente Vascular Cerebral/reabilitação , Extremidade Superior/fisiopatologia , Terapia Combinada , Terapia por Exercício , Literatura de Revisão como AssuntoRESUMO
OBJECTIVE: To evaluate the sensitivity and reproducibility of the Basso, Beattie, Bresnahan functional scale in the assessment of the locomotor capacity of rats after spinal cord injury. METHODS: Thirty male Wistar rats underwent laminectomy and mild, moderate or severe spinal cord contusions using the New York University Weight Drop Impactor. The mice were followed for 28 days, after which time each rat was placed in an 80x80x30 cm³ clear box lined with a blue non-slippery material and stimulated to move. Their movement was video-recorded by three digital cameras operating simultaneously. Identical copies of the edited videos were given to six independent evaluators who were blinded with regards to the degree of injury severity. Each evaluator made a determination of the locomotor capacity of the rats using the Basso, Beattie, Bresnahan functional scale. RESULTS: We determined the sensitivity of the method to differences among the evaluators as well as between the results achieved on the left and right hind paws of rats subjected to either mild, moderate or severe injuries by comparing the functional outcomes and reproducibility using non-parametric correlation tests. CONCLUSIONS: The Basso, Beattie, Bresnahan scale showed high reproducibility and satisfactory sensitivity for identifying mild injuries; satisfactory reproducibility and non-satisfactory sensitivity for moderate injuries; and reduced reproducibility and non-satisfactory sensitivity for severe injuries.