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ABSTRACT Purpose: To investigate ocular surface and meibomian glands in patients with treatment-naive acne vulgaris. Methods: The Ocular Surface Disease Index (OSDI) questionnaire, invasive tear film breakup time, fluorescein staining of the ocular surface, and Schirmer II test were performed for all subjects. Total eyelid and meibomian gland secretion scores were assessed. Non-contact meibography was performed with the Sirius corneal topographic device. Results: The right eyes of 35 patients with acne vulgaris and 35 healthy volunteers were included the study. While the OSDI and staining scores were significantly higher in the acne group than in the control group (p=0.01 and p=0.003, respectively), the invasive tear film breakup time and Schirmer measurements were significantly lower in the acne group (p=0.000 and p=0.003, respectively). The total eyelid and meibomian gland secretion scores were also higher in the acne group than in the control group (p=0.003 and p=0.000, respectively). On the morphological evaluation of the meibomian glands, the thickening, thinning, tortuosity, and presence of ghost areas were statistically significantly more common in the acne vulgaris group than in the control group (p=0.000, p=0.001, p=0.05, and p=0.006, respectively). The percentage of the meibomian gland loss area was significantly high in the acne vulgaris group on both upper and lower meibography. The meibomian gland loss area positively correlated with total eyelid and meibomian gland secretion scores. Conclusion: Acne vulgaris may have a predisposition to meibomian gland dysfunction and ocular surface damage. Early recognition of meibomian gland and ocular surface alterations seems important, especially in acne vulgaris cases for which oral isotretinoin treatment is planned.

RESUMO Objetivo: Todos os indivíduos responderam ao questionário Ocular Surface Disease Index (OSDI) e tiveram avaliados o tempo de ruptura do filme lacrimal pelo método invasivo, a coloração da superfície ocular com fluoresceína e o teste de Schirmer II. Foram ainda avaliados o escore palpebral total e o de secreção das glândulas meibomianas. Foi realizada meibografia sem contato com um dispositivo topográfico corneano Sirius. Métodos: Todos os indivíduos responderam ao questionário Ocular Surface Disease Index (OSDI) e tiveram avaliados o tempo de ruptura do filme lacrimal pelo método invasivo, a coloração da superfície ocular com fluoresceína e o teste de Schirmer II. Foram ainda avaliados o escore palpebral total e o de secreção das glândulas meibomianas. Foi realizada meibografia sem contato com um dispositivo topográfico corneano Sirius. Resultados: Foram incluídos no estudo os olhos direitos de 35 voluntários com acne vulgar e 35 saudáveis. Os escores do Ocular Surface Disease Index e da coloração foram significativamente maiores no grupo com acne em comparação com o grupo controle (p=0,01 e p=0,003, respectivamente), mas o tempo de ruptura do filme lacrimal pelo método invasivo e as medidas do teste de Schirmer II foram significativamente menores (p=0,000 e p=0,003, respectivamente). O escore palpebral total e o escore de secreção das glândulas meibomianas também foram maiores no grupo com acne que no grupo controle (p=0,003 e p=0,000). Na avaliação morfológica das glândulas meibomianas, o espessamento, o afinamento, a tortuosidade e a presença de áreas fantasmas nas glândulas foram mais comuns no grupo acne vulgar que no grupo controle, com significância estatística (p=0,000, p=0,001, p=0,05 e p=0,006 respectivamente). A porcentagem da área de perdas das glândulas meibomianas foi significativamente mais alta no grupo com acne vulgar, tanto na meibografia superior quanto na inferior. A área de perda das glândulas meibomianas demonstrou uma correlação positiva com o escore palpebral total e com o escore de secreção das glândulas meibomianas. Conclusão: A acne vulgar pode levar a uma predisposição para a disfunção das glândulas meibomianas e para danos na superfície ocular. Parece ser importante reconhecer precocemente as alterações das glândulas meibomianas e da superfície ocular, especialmente nos casos de acne vulgar para os quais se planeja o tratamento oral com isotretinoína.

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ABSTRACT Purpose: To evaluate the variables possibly related to actinic keratosis and malignant skin lesions on the eyelid. Methods: A prospective study of patients with suspected eyelid malignancy was conducted. The participants underwent a 2-mm punch biopsy at two opposite sites of the lesion for diagnosis, and the results were compared with those of the histopathological study of the surgical excised specimen. The patients with an actinic keratosis component were divided into two groups (actinic keratosis-associated malignancy and actinic keratosis alone), which were compared for the following variables: age, disease duration, largest diameter, tumor area, Fitzpatrick classification, sex, tumor site and margin involvement. A cluster analysis was also performed. Results: We analyzed 174 lesions, of which 50 had an actinic keratosis component. Actinic keratosis was associated with squamous cell carcinoma in 22% of the cases and to basal cell carcinoma in 38%, which shows that both neoplasms may have contiguous actinic keratosis. Statistical analysis revealed no significant difference among the variables. In a cluster analysis, four groups were identified with malignant lesions in the medial canthus with the largest mean diameter and area. All margin involvements on the lower eyelid were related to malignancy, which means that all cases with margin involvement had an almost 100% risk of malignancy. Conclusions: Larger actinic keratosis lesions in the medial canthus and lesions with margin involvement on the lower eyelid have a greater probability of malignant association.

RESUMO Objetivo: Avaliar as possíveis variáveis relacionadas à ceratose actínica e lesões malignas cutâneas nas pálpebras. Métodos: Estudo prospectivo de pacientes com lesões palpebrais suspeitas de malignidade. Os participantes foram submetidos à biopsia por trépano (punch) de 2-mm em dois pontos opostos da lesão como método diagnóstico e os resultados foram comparados com o estudo histopatológico da peça excisada cirurgicamente. Aqueles que apresentaram ceratose actínica como resultado foram divididos em dois grupos (ceratose actínica associada com malignidade e ceratose actínica isolada) e foram comparados de acordo com as variáveis: idade, tempo de doença, maior diâmetro, área do tumor, classificação de Fitzpatrick, gênero, localização e acometimento da margem palpebral. A análise de cluster também foi realizada. Resultados: Foram analisadas 174 lesões e 50 delas tinham ceratose actínica como componente do tumor. Ceratose actínica esteve associada ao Carcinoma Espinocelular em 22% dos casos e ao Carcinoma Basocelular em 38%, mostrando que ambos podem ter ceratose actínica adjacente. A análise estatística não encontrou diferença entre as variáveis. A análise de cluster identificou quatro grupos e mostrou que lesões malignas no canto medial tinham maiores diâmetro e área. Acometimento da margem na pálpebra inferior relacionou-se em 100% com malignidade, enquanto a ausência de acometimento da margem mostrou menor chance de malignidade. Conclusões: Lesões maiores de ceratose actínica no canto medial e lesões com acometimento da margem palpebral inferior têm maiores chances de associação com malignidade.

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Background: Eversion of the cartilage of the third eyelid is a rare congenital disease in cats. It is caused by the anterioreversion of the cartilage edge of the third eyelid. Clinical signs may be associated with secondary keratoconjunctivitis,third eyelid gland protrusion, and ocular surface irritation. The diagnosis is made by ophthalmic examination, and treatment consists of surgical resection of the everted cartilage portion. The goal of the present study was to report a case ofeversion of third eyelid cartilage in a cat, given that it is an unusual abnormality in this animal species, and an importantdifferential diagnosis to be considered in the disorders of the third eyelid.Case: A 6-year-old neutered female Persian cat was presented with a presumptive diagnosis of protrusion of the thirdeyelid gland, history of ocular irritation, and epiphora in the left eye. The disorder had been intermittently present sincethe animal was 1-year-old, with spontaneous disappearance after approximately 15 days. The owner related the reappearance of the disorder to stressful situations, with no previous history of trauma or other ocular alteration. During theophthalmic examination, suspended solute was observed through biomiscroscopic examination in both eyes, as well asan increase in volume of the third eyelid in the left eye, without other changes. A thorough examination, under generalanesthesia, indicated the protruding volume of the cartilage of the everted third eyelid. The third eyelid was pleated inits upper portion, demonstrating that the cartilage of the third eyelid was folded instead of following the curvature of theocular surface. Under general anesthesia, the cartilage was partially removed through two parallel incisions on the bulbarconjunctival surface, divulsioning 5 mm in length in the vertical portion of the cartilage in a ‘T shape, and separating the...(AU)

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Background: Eversion of the cartilage of the third eyelid is a rare congenital disease in cats. It is caused by the anterioreversion of the cartilage edge of the third eyelid. Clinical signs may be associated with secondary keratoconjunctivitis,third eyelid gland protrusion, and ocular surface irritation. The diagnosis is made by ophthalmic examination, and treatment consists of surgical resection of the everted cartilage portion. The goal of the present study was to report a case ofeversion of third eyelid cartilage in a cat, given that it is an unusual abnormality in this animal species, and an importantdifferential diagnosis to be considered in the disorders of the third eyelid.Case: A 6-year-old neutered female Persian cat was presented with a presumptive diagnosis of protrusion of the thirdeyelid gland, history of ocular irritation, and epiphora in the left eye. The disorder had been intermittently present sincethe animal was 1-year-old, with spontaneous disappearance after approximately 15 days. The owner related the reappearance of the disorder to stressful situations, with no previous history of trauma or other ocular alteration. During theophthalmic examination, suspended solute was observed through biomiscroscopic examination in both eyes, as well asan increase in volume of the third eyelid in the left eye, without other changes. A thorough examination, under generalanesthesia, indicated the protruding volume of the cartilage of the everted third eyelid. The third eyelid was pleated inits upper portion, demonstrating that the cartilage of the third eyelid was folded instead of following the curvature of theocular surface. Under general anesthesia, the cartilage was partially removed through two parallel incisions on the bulbarconjunctival surface, divulsioning 5 mm in length in the vertical portion of the cartilage in a ‘T’ shape, and separating the...

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Background: The cutaneous squamous cell carcinoma (cSCC) is considered to be a frequent neoplasm in dogs, however,its origin in ocular annexes, especially in relation to the conjuctival location, is a rare finding in dogs. Therefore, it wasaimed to report the occurrence of a multicentric SCC, with the involvement of ocular annexes in a dog, emphasizing itsclinical characteristics and histopathological findings.Case: A 6-year-old non-castrated white-coated Pitbull dog was attended, with a history of increased volume and bloodysecretion in the left eye, with an evolution of approximately six months. By means of general physical examination, ulcerated lesions in the foreskin and scrotum were found. During the ophthalmologic examination was identified an extensiveand irregular exophytic mass, of a reddish color and with a cauliflower-like appearance, located in the inferior bulbarconjunctiva and third eyelid of the left eye, accompanied by a large quantity of piosanguinolenta secretion, mainly duringmanipulation. Other alterations were observed, such as, meibomitis, conjuctival hyperemia, hypopyon, corneal edema andloss of sight. In the right eye, the only alteration found was conjunctival hyperemia. The hemograma revealed discreetanemia; the serum biochemical profile was inside the normal range and there was no evidence of metastasis in the imaging examinations. The animal was submitted to the incisional biopsy of the lesions for histopathological analysis, whichrevealed a proliferation of neoplastic epithelial cells, highly pleomorphic, composed of eosinophilic cytoplasm, whichvaried from scarce to moderate, of indistinct borders, with a large nucleus and loose chromatin and large and evidentnucleolus, compatible with SCC, enabling, also, the classification as multicentric...(AU)

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This study aims to describe the first Brazilian report of a nictitating membrane cyst's surgical treatment in a dog. A 6-month-old female French Bulldog presented at HOSVET-UNIME with a reddish mass-like structure in the medial canthus of both eyes, with a history of recurrent third eyelid gland prolapse previously treated with two surgeries performed at another clinic. Physical examination revealed a third eyelid gland prolapse in the right eye and a cyst in the left eye's third eyelid. The animal was submitted to surgical correction of the right eye's third eyelid prolapse using pocket technique and of the left eye's third eyelid using marsupialization technique for the cyst's treatment. 180 days after th1e surgical procedure no recurrence was observed. The marsupialization technique for the treatment of a third eyelid's lacrimal cyst in a dog allowed the maintenance of its gland and prevented the formation of a new cystic cavity.(AU)

O objetivo do presente trabalho é descrever o primeiro relato no Brasil de tratamento cirúrgico de um cisto da membrana nictitante em um cão. Um Buldogue Francês, fêmea, seis meses, foi atendido no Hosvet-Unime, com queixa de aumento de volume avermelhado no canto medial de ambos os olhos, com histórico de recidiva de prolapso de glândula da terceira pálpebra, onde haviam sido realizadas duas cirurgias anteriormente em outro local. Ao exame físico, foi observado prolapso de glândula da terceira pálpebra no olho direito e a presença de um cisto na terceira pálpebra do olho esquerdo. O animal foi submetido ao procedimento cirúrgico de sepultamento de glândula da terceira pálpebra no olho direito e uma marsupialização na terceira pálpebra do olho esquerdo para o tratamento do cisto. Cento e oitenta dias após o procedimento cirúrgico, não foi observada recidiva. A técnica de marsupialização para tratamento de cisto lacrimal na terceira pálpebra em um cão possibilitou a manutenção da sua glândula e impediu a formação de nova cavidade cística.(AU)

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This study aims to describe the first Brazilian report of a nictitating membrane cyst's surgical treatment in a dog. A 6-month-old female French Bulldog presented at HOSVET-UNIME with a reddish mass-like structure in the medial canthus of both eyes, with a history of recurrent third eyelid gland prolapse previously treated with two surgeries performed at another clinic. Physical examination revealed a third eyelid gland prolapse in the right eye and a cyst in the left eye's third eyelid. The animal was submitted to surgical correction of the right eye's third eyelid prolapse using pocket technique and of the left eye's third eyelid using marsupialization technique for the cyst's treatment. 180 days after th1e surgical procedure no recurrence was observed. The marsupialization technique for the treatment of a third eyelid's lacrimal cyst in a dog allowed the maintenance of its gland and prevented the formation of a new cystic cavity.(AU)

O objetivo do presente trabalho é descrever o primeiro relato no Brasil de tratamento cirúrgico de um cisto da membrana nictitante em um cão. Um Buldogue Francês, fêmea, seis meses, foi atendido no Hosvet-Unime, com queixa de aumento de volume avermelhado no canto medial de ambos os olhos, com histórico de recidiva de prolapso de glândula da terceira pálpebra, onde haviam sido realizadas duas cirurgias anteriormente em outro local. Ao exame físico, foi observado prolapso de glândula da terceira pálpebra no olho direito e a presença de um cisto na terceira pálpebra do olho esquerdo. O animal foi submetido ao procedimento cirúrgico de sepultamento de glândula da terceira pálpebra no olho direito e uma marsupialização na terceira pálpebra do olho esquerdo para o tratamento do cisto. Cento e oitenta dias após o procedimento cirúrgico, não foi observada recidiva. A técnica de marsupialização para tratamento de cisto lacrimal na terceira pálpebra em um cão possibilitou a manutenção da sua glândula e impediu a formação de nova cavidade cística.(AU)

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Resumo O carcinoma de glândulas sebáceas (CGS) é a terceira neoplasia maligna mais frequente nas pálpebras. Acomete geralmente mulheres idosas e pode simular blefarite ou calázio. A reconstrução da pálpebra superior é sempre desafiadora. O objetivo deste é relatar um caso inusitado de CGS na pálpebra superior de indivíduo jovem e do sexo masculino. Foi realizada a ressecção total da pálpebra superior direita e o exame histológico revelou margens livres. A reconstrução foi feita com dois procedimentos cirúrgicos em tempos diferentes. Devido ao fato do CGS apresentar alto potencial de metástases, o paciente continua em acompanhamento para reavaliação funcional e estética.

Abstract Sebaceous gland carcinoma (SGC) is the third most frequent malignant neoplasm in the eyelids. It usually affects elderly women and can simulate blepharitis or chalazion. Upper eyelid reconstruction is always challenging. The purpose of this is to report an unusual case of SGC in the upper eyelid of a young and male patient. Total resection of the right upper eyelid was performed and histological examination revealed free margins. The reconstruction was done with two surgical procedures at different times. Due to the fact that SGC presents a high potential for metastasis, the patient continues to be followed for functional and aesthetic reevaluation.

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Background: The cutaneous squamous cell carcinoma (cSCC) is considered to be a frequent neoplasm in dogs, however,its origin in ocular annexes, especially in relation to the conjuctival location, is a rare finding in dogs. Therefore, it wasaimed to report the occurrence of a multicentric SCC, with the involvement of ocular annexes in a dog, emphasizing itsclinical characteristics and histopathological findings.Case: A 6-year-old non-castrated white-coated Pitbull dog was attended, with a history of increased volume and bloodysecretion in the left eye, with an evolution of approximately six months. By means of general physical examination, ulcerated lesions in the foreskin and scrotum were found. During the ophthalmologic examination was identified an extensiveand irregular exophytic mass, of a reddish color and with a cauliflower-like appearance, located in the inferior bulbarconjunctiva and third eyelid of the left eye, accompanied by a large quantity of piosanguinolenta secretion, mainly duringmanipulation. Other alterations were observed, such as, meibomitis, conjuctival hyperemia, hypopyon, corneal edema andloss of sight. In the right eye, the only alteration found was conjunctival hyperemia. The hemograma revealed discreetanemia; the serum biochemical profile was inside the normal range and there was no evidence of metastasis in the imaging examinations. The animal was submitted to the incisional biopsy of the lesions for histopathological analysis, whichrevealed a proliferation of neoplastic epithelial cells, highly pleomorphic, composed of eosinophilic cytoplasm, whichvaried from scarce to moderate, of indistinct borders, with a large nucleus and loose chromatin and large and evidentnucleolus, compatible with SCC, enabling, also, the classification as multicentric...

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Abstract Background: Eye-related neoplasms in dogs have a significant impact on visual ability, comfort, and longevity. Therapeutic alternatives and prognosis vary according to type of neoplasm and its anatomical location. Objective: To describe the frequency and distribution of eye-related neoplasms affecting dogs in the Aburrá valley (Antioquia province, Colombia). Methods: A retrospective collection of eye-related neoplasms in dogs, diagnosed at the Animal Pathology Laboratory of Universidad de Antioquia (Colombia), was conducted. Data spanning from years 2005 to 2017 were used. Records included age, sex, breed, neoplasm type and location, and cellular origin of neoplasm. A total of 250 eye-related-neoplasm reports affecting 246 dogs were analyzed -one report per animal, with the exception of four animals with both eyes simultaneously affected by the same type of neoplasm. Results: Animals between 8 and 11 years of age were more frequently affected by eye-related neoplasms (43.9%). Labrador retriever (19.1%), mixed-breed dogs (13.4%), and Poodle (12.2%) were the most frequently affected breeds. Neoplasms affected the eyelid in 76.8% of cases. Meibomian gland adenoma was the most frequent neoplasm (22.8%), followed by Meibomian gland epithelioma (20.0%), squamous cell carcinoma (8.8%), and melanocytoma (7.2%). The cellular origin of neoplasms was epithelial in 73.6% of the cases. Conclusion: Meibomian gland adenoma was the most common eye-related neoplasm. To our knowledge, this is the first retrospective report aimed to eye-related neoplasms in dogs published in Colombia.

Resumen Antecedentes: Las neoplasias relacionadas con los ojos en perros tienen un impacto significativo en la capacidad visual, la comodidad y la longevidad del animal. Las opciones terapéuticas y el pronóstico para el perro y para el tejido afectado varían según el tipo de neoplasia y su ubicación anatómica. Objetivo: Describir la frecuencia y distribución de neoplasias relacionadas con los ojos en perros del Valle de Aburrá (Departamento de Antioquia, Colombia). Métodos: Se realizó una evaluación retrospectiva de neoplasias relacionadas con los ojos en perros, diagnosticadas en el laboratorio de patología animal de la Universidad de Antioquia (Colombia). Los registros incluyeron información de 13 años (2005-2017). Los datos recolectados incluyeron edad, sexo, raza, tipo de tumor y ubicación, y origen celular de la neoplasia. Resultados: Se analizó un total de 250 reportes de neoplasias relacionadas con los ojos, afectando 246 perros (un reporte por animal, excepto cuatro animales en los que ambos ojos fueron afectados simultáneamente por el mismo tipo de neoplasia. Los animales entre 8 y 11 años de edad fueron los más frecuentemente afectados por neoplasias relacionadas con los ojos (43,9%). Las razas Labrador retriever (19,1%), perros mestizos (13,4%) y Poodle (12,2%) fueron las más frecuentemente afectadas. Las neoplasias afectaron el párpado en el 76,8% de los casos. El adenoma de la glándula de Meibomio fue la neoplasia más frecuente (22,8%), seguida por el epitelioma de la glándula de Meibomio (20,0%), el carcinoma de células escamosas (8,8%) y el melanocitoma (7,2%). El origen celular de las neoplasias fue epitelial en el 73,6% de los casos. Conclusión: Se encontró que el adenoma de la glándula de Meibomio es la neoplasia ocular más común. Hasta donde sabemos, este es el primer reporte retrospectivo dirigido específicamente a neoplasias relacionadas con ojos en perros publicado en Colombia.

Resumo Antecedentes: As neoplasias relacionadas aos olhos em cães são importantes porque têm um impacto significativo na capacidade visual, conforto e longevidade do animal. As opções terapêuticas e o prognóstico para o cão e para o tecido afetado variam de acordo com o tipo de neoplasia e sua localização anatômica. Objetivo: Descrever a frequência e distribuição das neoplasias relacionadas aos olhos em cães do Valle de Aburrá (Estado de Antioquia, Colômbia). Métodos: Foi realizada uma coleta retrospectiva de neoplasias relacionadas aos olhos em cães diagnosticados no laboratório de patologia animal da Universidade de Antioquia (Colômbia). Os registros coletaram informações de 13 anos (2005-2017). Os dados coletados incluíram idade, sexo, raça, tipo de tumor e localização e origem celular da neoplasia. Resultados: Um total de 250 relatos de neoplasias relacionadas aos olhos foram analisados, afetando 246 cães (um relatório por animal, com exceção de quatro animais, em que ambos os olhos foram afetados simultaneamente para o mesmo tipo de neoplasia relacionada aos olhos). Animais entre 8 e 11 anos foram mais acometidos por neoplasias relacionadas aos olhos (43,9%). As raças Labrador retriever (19,1%), mestiças (13,4%) e Poodle (12,2%) foram as raças mais afetadas. Neoplasias afetaram a pálpebra em 76,8% dos casos. Adenoma da glândula Meibomiana foi a neoplasia mais frequente (22,8%), seguido por epitelioma glândula Meibomiana (20,0%), carcinoma de células escamosas (8,8%) e melanocitoma (7,2%). A origem celular das neoplasias foi epitelial em 73,6% dos casos. Conclusão: Este estudo constatou que o adenoma da glândula Meibomiana é a neoplasia ocular mais comum. Para nosso conhecimento, este é o primeiro relato retrospectivo especificamente voltado para as neoplasias relacionadas aos olhos em cães publicados até o momento na Colômbia.

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Surgical reconstruction of large facial defects may not be always possible, therefore extraoral maxillofacial prosthesis is a good restorative option. The oculopalpebral prosthesis has a natural appearance however it can be easily noticed because its eyelids do not move. For esthetic purposes, it is desirable that the prosthetic eyelids open and close synchronously with the contralateral eye, which provides a challenge to the prosthetic reconstruction of the oculopalpebral region. To improve the esthetic outcome, an oculopalpebral prosthesis prototype with mechanical and electric features allowing synchronization of the eyelid motion with the sound eye was planned, designed, and built. An oculopalpebral prosthesis was made in thermoactivated acrylic resin. A gap was created to accommodate an electrical system and allow free motion of a thin eyelid made of silicone attached to the appliance. The movable eyelid was made with medical grade silicone (SILASTIC® MDX4-4210) and connected to an electrical and electronic system responsible to command the opening and closing movements. This mechanical and electrical prototype with the system connected to a sensor, successfully captured the eyelid motion of the contralateral sound eye. The proposed mechanical and electrical system attached to an oculopalpebral prosthesis could successfully establish and synchronize the eyelid movements with the sound eye.

A reconstrução cirúrgica de grandes defeitos faciais pode não ser sempre possível, portanto, a prótese bucomaxilofacial extra-oral é uma boa opção restauradora. A prótese oculopalpebral tem uma aparência natural, mas pode ser facilmente notada pois as pálpebras não se movimentam. Para fins estéticos, é desejável que as pálpebras protéticas se abram e se fechem em sincronia com o olho contralateral, o que representa um desafio para a reconstrução protética da região oculopalpebral. Para melhorar o resultado estético, um protótipo de prótese oculopalpebral com características mecânicas e elétricas permitindo a sincronização do movimento da pálpebra com o olho sadio foi planejado, projetado e construído. Uma prótese oculopalpebral foi confeccionada em resina acrílica termoativada. Um nicho foi criada para acomodar umsistema elétrico e permitir o movimento livre de uma pálpebra fina confeccionada em silicone preso ao sistema. A pálpebra móvel foi confeccionada com silicone de grau médico (SILASTIC® MDX4-4210) e conectada a um sistema elétrico e eletrônico responsável por comandar os movimentos de abertura e fechamento. Esteprotótipo mecânico e elétrico com o sistema conectado a um sensor capturou com sucesso o movimento das pálpebras do olho acústico contralateral. O sistema mecânico e elétrico proposto, fixado a uma próteseoculopalpebral, conseguiu estabelecer e sincronizar os movimentos da pálpebra com o olho sadio.

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RESUMO

O melanoma é uma neoplasia maligna de melanócitos, os quais produzem a melanina responsável pela pigmentação da pele, descrito em várias espécies animais e em seres humanos. Em equinos, esse tipo tumoral representa grande parte dos comprometimentos cutâneos, principalmente em animais de pelagem tordilha; porém não se observa predileção racial e sexual, sendo a idade considerada um agravante na malignidade. Esta afecção acomete principalmente as regiões de cauda, períneo, orelhas e olhos, e ocasionalmente se desenvolvem em órgãos genitais; sendo que o curso clínico varia desde a invasão de órgãos até a disseminação metastática. Caracterizam-se por lesões firmes, nodulares, únicas ou múltiplas, de tamanhos e coloração variados, infiltrativas, podendo ocorrer ulcerações. Os sinais clínicos demonstrados pelos pacientes acometidos são variáveis, dependendo da localização tumoral. Em animais, o diagnóstico de melanoma está relacionado a um prognóstico desfavorável, pois, em geral, o tumor é detectado tardiamente, quando já houve infiltração local ou formação de metástases. Este trabalho tem como objetivo relatar um caso relacionado a melanoma de terceira pálpebra em um equino macho, com 13 anos de idade, raça Puro Sangue Lusitano (PSL), pelagem tordilha. O animal apresentava nódulos de tamanhos consideráveis na terceira pálpebra do olho direito, de coloração enegrecida, sendo submetido a procedimento cirúrgico para a remoção total do mesmo. O animal foi submetido a um protocolo pós-cirúrgico com antibioticoterapia local na forma de colírio (Ciprofloxacina 0,3mg ou 02 gotas), quatro vezes ao dia, durante dez dias e também sistêmica (Benzilpenicilina G Procaína 4000UI/Kg/PV) por via intramuscular, uma vez ao dia, durante cinco dias...(AU)

Melanoma is a malignant neoplasm of melanocytes which produce melanin, responsible for skin pigmentation, described in various animal species and in humans. In equines, this tumor type represents a large part of the mainly in fur animals; but there is no racial and sexual predilection, and age is considered an aggravating factor in malignancy. This condition mainly affects the tail, perineum, auricular and ocular regions and occasionally develops in the genital organs; and the clinical course varies from invasion of organs to metastatic dissemination. It is characterized by firm, nodular, single or multiple lesions of varying infiltrative sizes and staining, and ulcerations may occur. The clinical signs demonstrated by the affected patients are variable, depending on the tumor location. In animals, the diagnosis of melanoma is related to an unfavorable prognosis, since, in general, the tumor is detected late, when there has been local infiltration or formation of metastases. The aim of this study is to report a case related to third eyelid melanoma in a 13 year - old male Purebred Lusitano (PSL) equine breed. The animal presented nodules of considerable size in the third eyelid of the right eye, of blackened color, being submitted to surgical procedure for the total removal of the same one. The animal was submitted to a post-surgical protocol with local antibiotic therapy in the form of eye drops (Ciprofloxacin 0.3mg or 2 drops), four times a day for ten days and also systemic (Benzylpenicillin G Procaine 4000UI/Kg/PV) intramuscularly once daily for five days. As an anti-inflammatory protocol, it was used topically, eye drops (Flurbiprofen Sodium 0.03mg or 2 drops), four times a day for ten days and intravenously (Fenilbutazone 4.0mg/Kg/PV), once a day during five days, responding satisfactorily to the treatment.(AU)

Assuntos

RESUMO

O melanoma é uma neoplasia maligna de melanócitos, os quais produzem a melanina responsável pela pigmentação da pele, descrito em várias espécies animais e em seres humanos. Em equinos, esse tipo tumoral representa grande parte dos comprometimentos cutâneos, principalmente em animais de pelagem tordilha; porém não se observa predileção racial e sexual, sendo a idade considerada um agravante na malignidade. Esta afecção acomete principalmente as regiões de cauda, períneo, orelhas e olhos, e ocasionalmente se desenvolvem em órgãos genitais; sendo que o curso clínico varia desde a invasão de órgãos até a disseminação metastática. Caracterizam-se por lesões firmes, nodulares, únicas ou múltiplas, de tamanhos e coloração variados, infiltrativas, podendo ocorrer ulcerações. Os sinais clínicos demonstrados pelos pacientes acometidos são variáveis, dependendo da localização tumoral. Em animais, o diagnóstico de melanoma está relacionado a um prognóstico desfavorável, pois, em geral, o tumor é detectado tardiamente, quando já houve infiltração local ou formação de metástases. Este trabalho tem como objetivo relatar um caso relacionado a melanoma de terceira pálpebra em um equino macho, com 13 anos de idade, raça Puro Sangue Lusitano (PSL), pelagem tordilha. O animal apresentava nódulos de tamanhos consideráveis na terceira pálpebra do olho direito, de coloração enegrecida, sendo submetido a procedimento cirúrgico para a remoção total do mesmo. O animal foi submetido a um protocolo pós-cirúrgico com antibioticoterapia local na forma de colírio (Ciprofloxacina 0,3mg ou 02 gotas), quatro vezes ao dia, durante dez dias e também sistêmica (Benzilpenicilina G Procaína 4000UI/Kg/PV) por via intramuscular, uma vez ao dia, durante cinco dias...

Melanoma is a malignant neoplasm of melanocytes which produce melanin, responsible for skin pigmentation, described in various animal species and in humans. In equines, this tumor type represents a large part of the mainly in fur animals; but there is no racial and sexual predilection, and age is considered an aggravating factor in malignancy. This condition mainly affects the tail, perineum, auricular and ocular regions and occasionally develops in the genital organs; and the clinical course varies from invasion of organs to metastatic dissemination. It is characterized by firm, nodular, single or multiple lesions of varying infiltrative sizes and staining, and ulcerations may occur. The clinical signs demonstrated by the affected patients are variable, depending on the tumor location. In animals, the diagnosis of melanoma is related to an unfavorable prognosis, since, in general, the tumor is detected late, when there has been local infiltration or formation of metastases. The aim of this study is to report a case related to third eyelid melanoma in a 13 year - old male Purebred Lusitano (PSL) equine breed. The animal presented nodules of considerable size in the third eyelid of the right eye, of blackened color, being submitted to surgical procedure for the total removal of the same one. The animal was submitted to a post-surgical protocol with local antibiotic therapy in the form of eye drops (Ciprofloxacin 0.3mg or 2 drops), four times a day for ten days and also systemic (Benzylpenicillin G Procaine 4000UI/Kg/PV) intramuscularly once daily for five days. As an anti-inflammatory protocol, it was used topically, eye drops (Flurbiprofen Sodium 0.03mg or 2 drops), four times a day for ten days and intravenously (Fenilbutazone 4.0mg/Kg/PV), once a day during five days, responding satisfactorily to the treatment.

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RESUMO

A Yellow-headed Caracara (Milvago chimachima) was submitted to the Ophthalmology Service of the Federal University of Bahia with a corneal abnormality. During ophthalmic evaluation the right cornea was stained positively with fluorescein; a blurred bullous lesion, with irregular surface, compatible with the diagnosis of bullous keratopathy was found. This is a rare condition in a bird which was treated successfully with a modified third eyelid flap associated with antibiotic and hyaluronic acid eye drops. The adopted therapeutic proved to be simple to implement and viable for repair of the bullous keratopathy in the Yellow-headed caracara.(AU)

Um gavião carrapateiro (Milvago chimachima) foi encaminhado ao Serviço de Oftalmologia Veterinária da Universidade Federal da Bahia com alteração em córnea. Durante a avaliação oftálmica a prova da fluoresceína foi positiva no olho direito e foi observado lesão bolhosa de aspecto irregular, compatível com o diagnóstico de ceratopatia bolhosa. Esta é uma alteração rara em aves e no presente caso foi tratada através de "flap" modificado de terceira pálpebra associado a utilização de colírio antibiótico e ácido hialurônico. A terapêutica adotada foi de fácil implementação e viável no reparo da ceratopatia bolhosa em gavião carrapateiro.(AU)

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RESUMO

A Yellow-headed Caracara (Milvago chimachima) was submitted to the Ophthalmology Service of the Federal University of Bahia with a corneal abnormality. During ophthalmic evaluation the right cornea was stained positively with fluorescein; a blurred bullous lesion, with irregular surface, compatible with the diagnosis of bullous keratopathy was found. This is a rare condition in a bird which was treated successfully with a modified third eyelid flap associated with antibiotic and hyaluronic acid eye drops. The adopted therapeutic proved to be simple to implement and viable for repair of the bullous keratopathy in the Yellow-headed caracara.(AU)

Um gavião carrapateiro (Milvago chimachima) foi encaminhado ao Serviço de Oftalmologia Veterinária da Universidade Federal da Bahia com alteração em córnea. Durante a avaliação oftálmica a prova da fluoresceína foi positiva no olho direito e foi observado lesão bolhosa de aspecto irregular, compatível com o diagnóstico de ceratopatia bolhosa. Esta é uma alteração rara em aves e no presente caso foi tratada através de flap modificado de terceira pálpebra associado a utilização de colírio antibiótico e ácido hialurônico. A terapêutica adotada foi de fácil implementação e viável no reparo da ceratopatia bolhosa em gavião carrapateiro.(AU)

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ABSTRACT Purpose: The aim of this study is to describe a variation in technique of the frontalis sling surgery with silicone rods and its results, using an alternative needle with similar effectiveness to the Wright needle at a reduced cost. Methods: This was a prospective, interventional, noncomparative study of patients with severe ptosis who underwent surgical correction using a simple and modified frontalis sling surgery technique. Patients were included in this study from January 2012 to January 2014. 23 surgeries were performed on 15 patients. The minimum "follow-up" was 12 months. Results: Most patients had congenital ptosis (86%) and the average preoperative margin reflex distance 1 (MRD1) was -1.1 mm (range -3 to 0 mm). 1 week post-operation, this was 2.7 mm ( 1.8 to 3.8 mm), 1.8 mm after 1 month and 1.7 mm (1 to 2.5 mm) after one year. The satisfaction rate was 80% (12 patients). Among the dissatisfied patients, one had extrusion and infection with subsequent explantation of the wire, one had asymmetry greater than 2 mm and one had persistent lagophthalmos and punctate keratitis, with subsequent explantation of silicone. Conclusion: The use of silicone rods with tarsal fixation using an alternative needle was effective in the treatment of severe ptosis with few complication rates, a low rate of dissatisfaction and good stability of the results in the follow-up period.

RESUMO Objetivos: O objetivo deste estudo é descrever uma variação da técnica cirúrgica da suspensão ao músculo frontal com fio de silicone e seus resultados, utilizando uma agulha alternativa à agulha de Wright, com a mesma eficácia e melhor razão custo-benefício. Métodos: Foram analisados prospectivamente todos os casos de blefaroptose severa submetidos à correção cirúrgica, utilizando a técnica de suspensão ao músculo frontal modificada, no período de janeiro de 2012 à janeiro de 2014. Foram realizadas 23 cirurgias em 15 pacientes. O "follow-up" mínimo foi de 12 meses. Resultados: A grande maioria dos pacientes apresentavam blefaroptose congênita (86%), a média da distância margem reflexo pré-operatória foi de -1,1mm (-3 a 0 mm), no pós-operatório de 1 semana foi de 2,7 mm (1,8 a 3,8 mm), após 1 mês foi de 1,8 mm e após 1 ano, de 1,7mm (1 a 2,5 mm). O índice de satisfação foi de 80% (12 pacientes). Dos 3 pacientes insatisfeitos, 1 teve extrusão e infecção com posterior explante do fio, 1 apresentou assimetria maior que 2mm e 1 evoluiu com lagoftalmo persistente e ceratite puntacta, com posterior explante do silicone. Conclusão: O uso do fio de silicone com fixação tarsal usando uma agulha alternativa, se mostrou eficaz no tratamento da blefaroptose severa, com poucas complicações, baixo índice de insatisfação e boa estabilidade dos resultados no período de seguimento.

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Background: Eyelid coloboma or eyelid agenesis is the most common congenital disease in cats. It can affect both the upper and the lower lids and is commonly bilateral. This congenital defect has been reported in several breeds, such as Persian and Domestic Short-Haired Cat. Generally, this defect results in inversion of the colobomatous eyelid, which can cause trichiasis and inflammatory keratitis and corneal ulceration. The only effective treatment is blepharoplasty. This paper describes the clinical and surgical aspects of four patients treated by lip commissure to eyelid transposition for the repair of eyelid coloboma using the technique described in 2010. Results of this procedure have never been reported in Brazil.Cases: Seven eyes of four cats presenting eyelid coloboma affecting up to two thirds of the eyelid were evaluated in this study. Two of the four cats were males and two were females; their average age was 3 years. All patients were admitted at the same institution, and the main issues were purulent discharge and impaired vision. Diagnosis was based on physical and ophthalmic examination. Non-ulcerative keratitis was present in all cases. Corneal ulcer was diagnosed in three patients by the fluorescein dye test. In two cats, a corneo-conjunctival dermoid was found at the temporal-dorsal region of one eye, and measured approximately 0.3 mm; and the other two [...](AU)

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RESUMO

Background: Eyelid coloboma or eyelid agenesis is the most common congenital disease in cats. It can affect both the upper and the lower lids and is commonly bilateral. This congenital defect has been reported in several breeds, such as Persian and Domestic Short-Haired Cat. Generally, this defect results in inversion of the colobomatous eyelid, which can cause trichiasis and inflammatory keratitis and corneal ulceration. The only effective treatment is blepharoplasty. This paper describes the clinical and surgical aspects of four patients treated by lip commissure to eyelid transposition for the repair of eyelid coloboma using the technique described in 2010. Results of this procedure have never been reported in Brazil.Cases: Seven eyes of four cats presenting eyelid coloboma affecting up to two thirds of the eyelid were evaluated in this study. Two of the four cats were males and two were females; their average age was 3 years. All patients were admitted at the same institution, and the main issues were purulent discharge and impaired vision. Diagnosis was based on physical and ophthalmic examination. Non-ulcerative keratitis was present in all cases. Corneal ulcer was diagnosed in three patients by the fluorescein dye test. In two cats, a corneo-conjunctival dermoid was found at the temporal-dorsal region of one eye, and measured approximately 0.3 mm; and the other two [...]

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Objetivo: Apresentar a frequência de ocorrência do calázio em uma amostra populacional, assim como as características de seus portadores. Métodos: Estudo transversal utilizando amostra populacional aleatorizada, realizado nos anos 2004/2005, na região centro-oeste do estado de São Paulo. Os participantes foram avaliados segundo variáveis demográficas e exame oftalmológico. Resultados: A frequência de ocorrência do calázio foi de 1,56%, sendo mais frequente em mulheres, portadores de astigmatismo ou hipermetropia de pequenos graus, com grande variação de idade de acometimento. Foi necessária prescrição de correção óptica e cirurgia em número expressivo de casos. Conclusão: O calázio tem baixa frequência de ocorrência na população geral. Ocorre predominantemente em mulheres e há associação importante com ametropia.

Purpose: To show the frequency of occurrence of chalazion in a population sample, as well as the characteristics of patients. Methods: A cross-sectional study using randomized population sample was carried out during 2004/2005, in the Midwest region of the state of São Paulo. Participants were evaluated according to demographic variables and ocular examination. Results: The frequency of occurrence of chalazion was 1.56‰, more common in women, people with astigmatism or low hyperopia, with wide variation in age of onset. It was necessary to prescribe optical correction and surgery in a significant number of cases. Conclusion: The chalazion has low frequency of occurrence in the general population. It occurs predominantly in women and there is a significant association with refractive error.

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Las neoplasias oculares son frecuentes en la clínica oftalmológica de pequeños animales. Pueden ser primarias o secundarias, y su ubicación en el globo ocular o anexos puede desencadenar consecuencias que van desde la pérdida de la estética hasta afectar la funcionalidad del ojo. Este artículo presenta un caso de angioqueratoma conjuntival en un canino, hembra, de raza mastín napolitano, de cinco años de edad, en la Clínica de Pequeños Animales de la Universidad Cooperativa de Colombia, sede Ibagué. La paciente fue atendida por presentar alteración ocular en ojo izquierdo, caracterizada por aumento de volumen e hiperemia de la conjuntiva del tercer párpado, con evolución de dos años. Durante el examen oftálmico fue encontrada secreción ocular de tipo mucosanguinolenta, hiperemia conjuntival y conjuntivitis folicular. En la paciente, después del examen clínico general y oftálmico, fue realizada biopsia de la lesión para evaluación histopatológica que determinó angioqueratoma en conjuntiva del tercer párpado, una neoplasia infrecuente en este tipo de tejido y en esta raza. El tratamiento realizado en este caso fue remoción quirúrgica, con resultados favorables, y llevó a la paciente a una completa eliminación de la neoplasia sin secuelas.

Ocular tumors are frequent in the eye clinic of small animals. They can be primary or secondary, and its location within the eyeball or its attachments may trigger consequences ranging from the loss of aesthetics to affecting the eye's functionality. This article presents a case of conjunctival angiokeratoma in a five-year-old female dog of Neapolitan Mastiff breed, in the Small Animal Clinic of Universidad Cooperativa de Colombia in Ibagué. The patient was treated for presenting ocular alteration in her left eye characterized by an increase of volume and hyperemia of the third eyelid conjunctiva, with a two-year evolution. During the ophthalmic examination, ocular mucosanguineous discharge, conjunctival hyperemia and follicular conjunctivitis were found. After general and ophthalmic clinical examination was performed, a biopsy of the lesion was performed for a histopathologic evaluation, which determined angiokeratoma in the third eyelid conjunctiva, a rare neoplasia in this type of tissue and in this breed. The treatment used in this case was surgical removal, with favorable results, which led to a complete removal of the tumor without sequelae in the patient.

As neoplasias oculares são frequentes na clínica oftalmológica de pequenos animais. Podem ser primárias ou secundárias, e sua localização no globo ocular ou anexos pode desencadear consequências que vão desde a perda da estética até afetar a funcionalidade do olho. Este artigo apresenta um caso de Angioqueratoma conjuntival em um canino, fêmea, de raça mastim napolitano, de cinco anos de idade, na Clínica de Pequenos Animais da Universidade Cooperativa da Colômbia, sede Ibagué. A paciente foi atendida porque apresentava alteração ocular no olho esquerdo, caracterizada por aumento de volume e hiperemia da conjuntiva da terceira pálpebra, com evolução de dois anos. Durante o exame oftálmico foi encontrada secreção ocular de tipo muco sanguinolenta, hiperemia conjuntival e conjuntivite folicular. Na paciente, depois do exame clínico geral e oftálmico, foi realizada biopsia da lesão para avaliação histopatológica que determinou Angioqueratoma em conjuntiva da terceira pálpebra, uma neoplasia não muito frequente neste tipo de tecido e nesta raça. O tratamento realizado neste caso foi remoção cirúrgica, com resultados favoráveis, e levou a paciente a uma completa eliminação da neoplasia sem sequelas.