RESUMO

Objetivou-se avaliar o bloqueio sensitivo e motor da administração peridural de 0,2mL/kg de duas concentrações de ropivacaína em comparação à lidocaína em cães. Utilizaram-se 24 cães, distribuídos em quatro grupos: NaCl a 0,9% (GS), lidocaína a 2% (GL), ropivacaína a 0,5% (GR5) e ropivacaína a 0,75% (GR7,5). Avaliaram-se a presença de movimentação espontânea, deambulação, sensibilidade superficial e profunda nos momentos cinco, 10, 15, 20, 25, 30, 45, 60, 90, 120, 180, 240 e 300 minutos após peridural. O retorno à movimentação espontânea foi semelhante entre GL (42,50 ± 6,12) e GR7,5 (69,2 ± 58,9). O tempo para deambulação foi mais prolongado em GR7,5 (107,5 ± 79,3) que em GS (9,2 ± 3,8) e em GR5 (32,5 ± 20,9). O retorno da sensibilidade profunda foi maior em GR 7,5 (152,5 ± 89,2) que em GS (5,8 ± 2,0), GR5 (46,7 ± 46,3) e GL (52,5 ± 20,7). O tempo de retorno da sensibilidade superficial foi maior em GR7,5 (205,0 ± 129,3) que em GS (7,5 ± 2,7), GL (72,5 ± 19,9) e GR5 (97,5 ± 55,1). Apesar do retorno precoce da movimentação, ropivacaína 0,75% está relacionada a tempo prolongado de recuperação da função muscular e bloqueio sensitivo mais prolongado que lidocaína e ropivacaína 0,5%.(AU)

The aim of the present study was to evaluate the sensory and motor blockade of epidural 0.5% and 0.75% Ropivacaine or Lidocaine in dogs. Twenty-four dogs were distributed in four groups: 0.9% NaCl (GS), 2% lidocaine (GL), 0.5% ropivacaine (GR5) and 0.75% ropivacaine (GR7.5). Spontaneous movement, ability to walk, superficial, and deep pain response were assessed 5, 10, 15, 20, 25, 30, 45, 60, 90, 120, 180, 240 and 300 minutes after epidural. Time to return to spontaneous movement was similar between GL (42.50 ± 6.12) and GR7.5 (69.2 ± 58.9). Time to return to ambulation was longer in GR7.5 (107.5 ± 79.3) than in GS (9.2 ± 3.8) and GR5 (32.5 ± 20.9). Time to recover deep sensitivity was longer in GR 7.5 (152.5 ± 89.2) than in GS (5.8 ± 2.0), GR5 (46.7 ± 46.3) and GL (52.5 ± 20.7). Time to return superficial sensitivity was longer in GR7.5 (205.0 ± 129.3) when compared to GS (7.5 ± 2.7), GL (72.5 ± 19.9) and GR5 (97.5 ± 55.1). Despite the early return of spontaneous movement, 0.75% ropivacaine is related to longer periods for muscle function recovery and longer sensory block than lidocaine and 0.5% ropivacaine.(AU)

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RESUMO

Background: The epidural administration of local anaesthetic agents was advocated for use in any surgical procedure caudal to the diaphragm in dogs but was superior for procedures involving the pelvis, hind limbs, and perineal area. The aim of this study was to determine anaesthetic profiles of bupivacaine (BP) and levobupivacaine (LP) in epidural anaesthesia (EA) and to compare their effects on hemodynamics, blood gases, hematological and biochemical parameters in conscious dogs. Materials, Methods & Results: In this study, a total of 20 adult male dogs from different breeds referred to our clinics for castration purposes were used and allocated into two groups; 10 dogs in BP and 10 dogs in LP groups. In this study, each animal received a 0.5% of either BP or LP epidurally, (a fixed total volume of 0.2 mL/kg) followed by 0.3 mL saline solution to flush the dead space in the valve and catheter. Throughout the epidural anaesthesia, heart rate, respiratory rate, systolic and diastolic blood pressure, mean arterial blood pressure, and body temperature were monitored. Similarly, during the study, haematological measurements at 0th, 2nd, 4th, 6th, and 8th h and biochemical measurements at 0th, 2nd, 4th, 6th, 8th and 24th h in blood samples were examined. Simultaneously, blood gases, and Na+ and K+ levels in arterial blood samples were measured at 0th, 30th, 60th, 120th and 240th min. Nocifensive and motor block status were qualitatively assessed at regular intervals: baseline, 5, 10, 15, 30, 45, 60, 75, 90, 105, 120 min and every 30 min thereafter. Duration of the analgesia was 124.9 ± 28.6 min in the BP group and 77.5 ± 16.8 min in the LP group (P < 0.05). Motor block duration was determined as 248.2 ± 44.2 min for the BP group and 185.9 ± 38.08 min for the LP group (P > 0.05). Motor and sensory block time was longer in the BP group than in the LP group, and similarly, BP generated sensory and motor block in a shorter period of time. While complete motor block was not observed in two animals in the LP group, complete motor block was seen in all the animals in the BP group. Motor block level was determined as 2.8 ± 0.4 in the LP group and 3 ± 00 in the BP group. There were no statistically significant differences between the levels of motor block. In both groups, decreased heart rate and arterial blood pressure were seen following EA. This decline was higher in the BP group. After epidural anaesthesia, slight decline in respiratory rate and body temperature were observed in both groups. There were no significant differences between the groups regarding cardiopulmonary data. Within each group, statistically significant changes in respiratory rates, body temperatures and blood pressures with regards to times were observed in both groups (P < 0.05). Discussion: Similar to the data in the literature, the duration of analgesia and motor block were longer with BP than with LP, and both agents showed close initiation analgesia and motor blockade. The reason for longer motor block by BP may be attributed to its higher lipophilic nature and penetration ability to the myeliniated motor fibrils. In present study, arterial blood pressure dropped, and this was higher in the BP group than in the LP group. These drops were attributed to the ability of sympathetic blockade of BP and LP.

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RESUMO

Background: The epidural administration of local anaesthetic agents was advocated for use in any surgical procedure caudal to the diaphragm in dogs but was superior for procedures involving the pelvis, hind limbs, and perineal area. The aim of this study was to determine anaesthetic profiles of bupivacaine (BP) and levobupivacaine (LP) in epidural anaesthesia (EA) and to compare their effects on hemodynamics, blood gases, hematological and biochemical parameters in conscious dogs. Materials, Methods & Results: In this study, a total of 20 adult male dogs from different breeds referred to our clinics for castration purposes were used and allocated into two groups; 10 dogs in BP and 10 dogs in LP groups. In this study, each animal received a 0.5% of either BP or LP epidurally, (a fixed total volume of 0.2 mL/kg) followed by 0.3 mL saline solution to flush the dead space in the valve and catheter. Throughout the epidural anaesthesia, heart rate, respiratory rate, systolic and diastolic blood pressure, mean arterial blood pressure, and body temperature were monitored. Similarly, during the study, haematological measurements at 0th, 2nd, 4th, 6th, and 8th h and biochemical measurements at 0th, 2nd, 4th, 6th, 8th and 24th h in blood samples were examined. Simultaneously, blood gases, and Na+ and K+ levels in arterial blood samples were measured at 0th, 30th, 60th, 120th and 240th

Background: The epidural administration of local anaesthetic agents was advocated for use in any surgical procedure caudal to the diaphragm in dogs but was superior for procedures involving the pelvis, hind limbs, and perineal area. The aim of this study was to determine anaesthetic profiles of bupivacaine (BP) and levobupivacaine (LP) in epidural anaesthesia (EA) and to compare their effects on hemodynamics, blood gases, hematological and biochemical parameters in conscious dogs. Materials, Methods & Results: In this study, a total of 20 adult male dogs from different breeds referred to our clinics for castration purposes were used and allocated into two groups; 10 dogs in BP and 10 dogs in LP groups. In this study, each animal received a 0.5% of either BP or LP epidurally, (a fixed total volume of 0.2 mL/kg) followed by 0.3 mL saline solution to flush the dead space in the valve and catheter. Throughout the epidural anaesthesia, heart rate, respiratory rate, systolic and diastolic blood pressure, mean arterial blood pressure, and body temperature were monitored. Similarly, during the study, haematological measurements at 0th, 2nd, 4th, 6th, and 8th h and biochemical measurements at 0th, 2nd, 4th, 6th, 8th and 24th h in blood samples were examined. Simultaneously, blood gases, and Na+ and K+ levels in arterial blood samples were measured at 0th, 30th, 60th, 120th and 240th

RESUMO

Background: The epidural administration of local anaesthetic agents was advocated for use in any surgical procedure caudal to the diaphragm in dogs but was superior for procedures involving the pelvis, hind limbs, and perineal area. The aim of this study was to determine anaesthetic profiles of bupivacaine (BP) and levobupivacaine (LP) in epidural anaesthesia (EA) and to compare their effects on hemodynamics, blood gases, hematological and biochemical parameters in conscious dogs. Materials, Methods & Results: In this study, a total of 20 adult male dogs from different breeds referred to our clinics for castration purposes were used and allocated into two groups; 10 dogs in BP and 10 dogs in LP groups. In this study, each animal received a 0.5% of either BP or LP epidurally, (a fixed total volume of 0.2 mL/kg) followed by 0.3 mL saline solution to flush the dead space in the valve and catheter. Throughout the epidural anaesthesia, heart rate, respiratory rate, systolic and diastolic blood pressure, mean arterial blood pressure, and body temperature were monitored. Similarly, during the study, haematological measurements at 0th, 2nd, 4th, 6th, and 8th h and biochemical measurements at 0th, 2nd, 4th, 6th, 8th and 24th h in blood samples were examined. Simultaneously, blood gases, and Na+ and K+ levels in arterial blood samples were measured at 0th, 30th, 60th, 120th and 240th

Background: The epidural administration of local anaesthetic agents was advocated for use in any surgical procedure caudal to the diaphragm in dogs but was superior for procedures involving the pelvis, hind limbs, and perineal area. The aim of this study was to determine anaesthetic profiles of bupivacaine (BP) and levobupivacaine (LP) in epidural anaesthesia (EA) and to compare their effects on hemodynamics, blood gases, hematological and biochemical parameters in conscious dogs. Materials, Methods & Results: In this study, a total of 20 adult male dogs from different breeds referred to our clinics for castration purposes were used and allocated into two groups; 10 dogs in BP and 10 dogs in LP groups. In this study, each animal received a 0.5% of either BP or LP epidurally, (a fixed total volume of 0.2 mL/kg) followed by 0.3 mL saline solution to flush the dead space in the valve and catheter. Throughout the epidural anaesthesia, heart rate, respiratory rate, systolic and diastolic blood pressure, mean arterial blood pressure, and body temperature were monitored. Similarly, during the study, haematological measurements at 0th, 2nd, 4th, 6th, and 8th h and biochemical measurements at 0th, 2nd, 4th, 6th, 8th and 24th h in blood samples were examined. Simultaneously, blood gases, and Na+ and K+ levels in arterial blood samples were measured at 0th, 30th, 60th, 120th and 240th

RESUMO

OBJECTIVE: The goal of the study was to investigate the regional intravenous anesthesia procedure in knee arthroscopy and to evaluate the effects of adding ketamine over the anesthesia block charactery and tourniquet pain. MATERIAL/METHOD: Forty American Society of Anesthesiologists (ASA) II patients who received knee arthroscopy were enrolled. After monitoring, a peripheral IV line was inserted.The venous blood in the lower extremity was evacuated with a bandage, and the proximal cuff of the double-cuff tourniquet was inflated. The patients were randomly split into two groups. While Group P received 80 ml 0.5 percent prilocaine, Group PK received 0.15 mg/kg ketamine (80 ml in total) via the dorsum of the foot. We recorded onset time of the sensory block, end time of the sensory block, presence of the motor block, the time when the patient verbally reported tourniquet pain and surgical pain, duration of tourniquet tolerance, fentanyl consumption during the operation, time to first analgesic requirement, methemoglobin values at 60 minutes, operative conditions, 24-hour analgesic consumption, discharge time, and hemodynamic parameters. RESULTS: The body mass index (BMI) of the patients who required general anesthesia was significantly higher than the BMI of other patients. The onset time of the sensory block was shorter for those in Group PK, but the time to first analgesic requirement was longer. CONCLUSION: Regional intravenous anesthesia using the doses and volumes commonly used in knee arthroscopy may be an inadequate block among patients with high BMI values. Moreover, the addition of ketamine to the local anesthetic solution may produce a partial solution by shortening the onset of sensory block and prolonging the time until the first analgesic is required.

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