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1.
Sci Total Environ ; 571: 983-91, 2016 Nov 15.
Artigo em Inglês | MEDLINE | ID: mdl-27453135

RESUMO

As one of the most impactful industries, coal mining can promote several alterations at surrounding environment. In surface water, elevated concentrations of metals like Mn, Zn, Fe and Al are often observed. Thus, the aim of this study was to investigate the bioaccumulation and the sub-lethal effects of these metals on various organs of the Neotropical bivalve Anodontites trapesialis confined along a stream located near a coal mine, in order to assess a set of biomarkers that could be used for effectively monitoring coal mining areas. Clams were caged, for 96h, at two sites located upstream (Up1 and Up2) and two sites downstream (Dw1 and Dw2) from the mine. Metals bioaccumulation was determined in gills, mantle, digestive gland, muscle and hemolymph and the following biomarkers were measured in A. trapesialis tissues: total antioxidant capacity against peroxyl radicals, metallothionein content, lipid peroxidation (LPO), proteins carbonylation, glutathione S-transferase activity, superoxide dismutase activity and acetylcholinesterase (AChE) activity. The results showed that Al and Fe bioaccumulation in the gills and hemolymph, Al bioaccumulation in the mantle and muscle, increased LPO in the gills (Dw1 and Dw2) and mantle (Dw1), as well as reduced AChE activity in the muscle (Dw1 and Dw2) should be considered effective biomarkers for monitoring coal mining areas. A. trapesialis proved to be an efficient biological model, considering that biomarkers responses were observed in the clams after only 96h of confinement at Dw sites, accordingly this species could be a good candidate for monitoring Neotropical freshwaters.


Assuntos
Bivalves/metabolismo , Monitoramento Ambiental/métodos , Metais/metabolismo , Poluentes Químicos da Água/metabolismo , Animais , Biomarcadores/metabolismo , Minas de Carvão
2.
Environ Sci Pollut Res Int ; 23(14): 13931-42, 2016 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-27040540

RESUMO

Landfills represent a severe environmental problem mainly due to the generation of leachates, and this study aimed to evaluate sublethal effects of a domestic landfill leachate in the freshwater bivalve Corbicula fluminea. Clams were submitted to in situ tests along a stream, at three sites, representing increasing distances from the leachate discharge (Pq1, Pq2, and Pq3), for 1, 5, and 15 days. The following biomarkers were analyzed in the gills and digestive glands: 7-ethoxyresorufin-O-deethylase (EROD) and glutathione S-transferase (GST) activities, multixenobiotic resistance mechanism (MXR), total antioxidant capacity (TAC), reactive oxygen species (ROS), and lipid peroxidation (LPO). Metallothionein (MT) content was determined in the gills and DNA damage in hemocytes. The mortality rate of animals during in situ tests was reduced as the distance from the leachate discharge source increased. On the other hand, biomarker results showed sublethal effects on C. fluminea confined at all sites of PqS. GST, TAC, ROS, and DNA damage were the most significant biomarkers for this species and should be considered for future monitoring and assessment of freshwater environments located in landfill areas.


Assuntos
Corbicula/metabolismo , Instalações de Eliminação de Resíduos , Poluentes Químicos da Água/metabolismo , Animais , Biomarcadores/metabolismo , Corbicula/química , Citocromo P-450 CYP1A1/metabolismo , Dano ao DNA , Brânquias/metabolismo , Glutationa Transferase/metabolismo , Peroxidação de Lipídeos/efeitos dos fármacos , Metalotioneína/metabolismo , Poluentes Químicos da Água/química
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