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1.
Schizophr Res ; 252: 13-22, 2023 02.
Artigo em Inglês | MEDLINE | ID: mdl-36610221

RESUMO

Visual illusions have long been used as tools to investigate sensory-perceptual deficits in schizophrenia. Recent conflicting accounts have called into question the assumption of abnormal illusion perception in patients and, therefore, the validity of this approach. Here, we present a systematic review of the current evidence regarding visual illusion perception abnormalities in patients with schizophrenia. Relevant publications were identified by a systematic search of PubMed, Literatura LILACS, PsycINFO, Embase, Scopus, Cochrane Central Register of Controlled Trials (CENTRAL), IBECS, BIOSIS, and Web of Science. Forty-five studies were selected which included illusions classified as 'Motion illusions', 'Geometric-optical illusions', 'Illusory contours', 'Depth inversion illusion', and 'Non-specific'. There is concordant evidence of abnormal processing of illusions in patients for most categories, especially in facial Depth Inversion and Müller-Lyer illusions. There were significant methodological disparities and shortcomings, but risk of bias was overall low for individual studies. The usefulness of visual illusions as tools in clinical settings as well as in basic research may be contingent on significant methodological refinements.


Assuntos
Percepção de Forma , Ilusões , Ilusões Ópticas , Esquizofrenia , Humanos , Percepção Visual
2.
Curr Pharm Des ; 28(33): 2725-2741, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36321314

RESUMO

BACKGROUND: Parkinson's disease (PD) is the second most common neurodegenerative disorder worldwide. The symptoms of PD are characterized not only by motor alterations but also by a spectrum of nonmotor symptoms. Some of these are psychiatric manifestations such as sleep disorders; depression; cognitive difficulties that can evolve into dementia; and symptoms of psychosis, which include hallucinations, illusions, and delusions. Parkinson's disease psychosis (PDP) occurs in 18-50% of patients with PD. Treating PDP is challenging because antipsychotic drugs tend to be inefficient or may even worsen the disease's motor symptoms. OBJECTIVE: This review aims to summarize the current understanding of the molecular mechanisms involved in PDP and recent innovative alternatives for its treatment. METHODS: This is a narrative review in which an extensive literature search was performed on the Scopus, EMBASE, PubMed, ISI Web of Science, and Google Scholar databases from inception to August 2021. The terms "Parkinson's disease psychosis", "Parkinson psychosis," "neurodegenerative psychosis", and "dopamine psychosis" were among the keywords used in the search. RESULTS: Recently, views on the etiology of hallucinations and illusions have evolved remarkably. PDP has been cemented as a multifactorial entity dependent on extrinsic and novel intrinsic mechanisms, including genetic factors, neurostructural alterations, functional disruptions, visual processing disturbances, and sleep disorders. Consequently, innovative pharmacological and biological treatments have been proposed. Pimavanserin, a selective 5-HT2A inverse agonist, stands out after its approval to treat PDP-associated hallucinations and illusions. CONCLUSION: Future results from upcoming clinical trials should further characterize the role of this drug in the management of PDP as well as other treatment options with novel mechanisms of action, such as saracatinib, SEP-363856, cannabidiol, electroconvulsive therapy, and transcranial magnetic stimulation.


Assuntos
Antipsicóticos , Ilusões , Doença de Parkinson , Transtornos Psicóticos , Transtornos do Sono-Vigília , Humanos , Doença de Parkinson/tratamento farmacológico , Dopamina , Transtornos Psicóticos/tratamento farmacológico , Alucinações/induzido quimicamente , Alucinações/tratamento farmacológico , Antipsicóticos/uso terapêutico , Ureia/farmacologia , Ureia/uso terapêutico , Transtornos do Sono-Vigília/induzido quimicamente
4.
Food Res Int ; 116: 126-134, 2019 02.
Artigo em Inglês | MEDLINE | ID: mdl-30716914

RESUMO

Restaurant workers, whether aware of this or not, may be responsible for spreading Foodborne Diseases (FBD) to consumers. The purpose of this article is to demonstrate how the knowledge of the risk of FBD can become a gateway to risk perception and cognitive illusions, and how the habitus acts in guiding work practices. The research uses a mixed-methods design with qualitative approach. A study was conducted in six food services during 42 days, which had participatory observation as central method. A Risk Perception Scale and a Locus of Control Questionnaire were applied, helping to obtain data relative to cognitive illusions. It was identified that in the absence of food safety knowledge, risk was not identified by the workers and the action was conditioned by the habitus or by the constructions of common sense, while in the presence of knowledge, although shallow, risk was perceived and cognitive illusions emerged. A relationship between the many years of work, inefficient training and the protection granted by objects in the presence of cognitive illusions is discussed. Workers who do not possess scientific knowledge need to go through consistent training that, beyond biological and hygiene-related content, encompass concepts interwoven with risk perception and the habitus.


Assuntos
Cognição , Manipulação de Alimentos/métodos , Inocuidade dos Alimentos/métodos , Conhecimentos, Atitudes e Prática em Saúde , Ilusões , Doenças Transmitidas por Alimentos/prevenção & controle , Humanos , Higiene , Restaurantes , Inquéritos e Questionários
5.
J. appl. oral sci ; J. appl. oral sci;27: e20180051, 2019. tab, graf
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-975887

RESUMO

Abstract The efficacy of whitening toothpastes is questionable and controversial. Clinicians, patients and researchers have expressed concern with whitening toothpastes due to the risk of wearing the dental structure and the potential for disappointment if the advertised cosmetic results are not achieved. Objective: This study compared the whitening performance of toothpastes with different whitening technologies after initial and continued use. Material and Methods: Ninety bovine incisors were stained using a concentrated solution of black tea. They were randomly distributed into 6 groups, according to the toothpaste whitening technology: activated charcoal (B&W), blue covarine (WAD), hydrogen peroxide (LWA), microbeads (Oral B 3D White Perfection - 3DW) and optimized abrasives (XW4D). They were compared to a traditional toothpaste without a whitening agent (TA - control). Specimens underwent a brushing machine with controlled pressure, time and temperature. A calibrated examiner measured the color using a VITA-Classical scale before the first brushing cycle (T0), after the first brushing cycle (TI), and after a brushing cycle that simulates continuous use (TCU). Whitening performance was evaluated by the difference of shades (ΔSGU) between T0-TI and T0-TCU timepoints, using the Kruskal-Wallis and Dunn's non-parametric test. The Wilcoxon test was used to evaluate the cumulative effect (α=0.05). Results: Statistically significant differences were observed between toothpastes in both TI and TCU (p<0.05). The time of use also had a significant effect (p<0.05). Conclusion: Only WAD and 3DW showed whitening performance after the first use (TI). The greatest whitening performance after continuous use was obtained by WAD, followed by LWA and 3DW. The use of conventional toothpaste (TA) promotes no tooth whitening. Clinical relevance: Microbead abrasives (3DW) and blue covarine (WAD) were the active technology tested that presented the best global tooth whitening performance.


Assuntos
Animais , Bovinos , Clareamento Dental/métodos , Cremes Dentais/química , Carvão Vegetal/química , Isoindóis/química , Clareadores Dentários/química , Peróxido de Hidrogênio/química , Metaloporfirinas/química , Microesferas , Valores de Referência , Propriedades de Superfície , Fatores de Tempo , Dente/efeitos dos fármacos , Escovação Dentária/métodos , Distribuição Aleatória , Reprodutibilidade dos Testes
6.
Dentomaxillofac Radiol ; 44(5): 20140360, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25629721

RESUMO

OBJECTIVES: This study aimed to assess how details on dental restorative composites with different radio-opacities are perceived under the influence of ambient light. METHODS: Resin composite step wedges (six steps, each 1-mm thick) were custom manufactured from three materials, respectively: (M1) Filtek™ Z350 (3M/ESPE, Saint Paul, MN); (M2) Prisma AP.H™ (Dentsply International Inc., Brazil) and (M3) Glacier(®) (SDI Limited, Victoria, Australia). Each step of the manufactured wedge received three standardized drillings of different diameters and depths. An aluminium (Al) step wedge with 12 steps (1-mm thick) was used as an internal standard to calculate the radio-opacity as pixel intensity values. Standardized digital images of the set were obtained, and 11 observers independently recorded the images, noting the number of noticeable details (drillings) under 2 dissimilar conditions: in a light environment (light was turned on in the room) and in low-light conditions (light in the room was turned off). The differences between images in terms of the number of details that were observed were statistically compared using ANOVA, Cronbach's alpha coefficient and Wilcoxon and Kruskal-Wallis tests, with a significance level setting of 5% (α = 0.05). RESULTS: The M2 showed higher radio-opacity, the M1 displayed intermediate radio-opacity and the M3 showed lower radio-opacity, respectively; however, all three were without significance (p > 0.05) compared with each other. The differences in radio-opacity resulted in a significant variation (p < 0.05) in the number of noticeable details in the image, which were influenced by characteristics of details, in addition to the ambient-light level. CONCLUSIONS: The radio-opacity of materials and ambient light can affect the perception of details in digital radiographic images.


Assuntos
Resinas Compostas , Luz , Radiografia Dentária Digital , Alumínio , Desenho de Equipamento , Imagens de Fantasmas , Cimentos de Resina
7.
Rev. peru. epidemiol. (Online) ; 17(2): 1-8, mayo.-ago. 2013. tab, graf
Artigo em Espanhol | LILACS, LIPECS | ID: lil-706066

RESUMO

Objetivo: Realizar la medición de la consistencia interna y el análisis factorial de la escala de desesperanza de Beck(EDB) al ser aplicada en puérperas adolescentes. Métodos: Se realizó un estudio observacional, analítico, de corte transversal. Se aplicó una encuesta a las adolescentes entre 13 y 18 años de edad, que cumplieran con los criterios deinclusión, que acudieran al Instituto Nacional Materno Perinatal (INMP) para la atención del parto entre los meses deenero a mayo de 2010. La consistencia interna se evaluó através del coeficiente alfa de Cronbach y la estructura factorial através de la extracción de componentes principales y rotación varimax. Resultados: Se obtuvo un coeficiente alfa de Cronbach = 0,70. La estructura factorial presenta seis dimensiones, que no se correlacionan con los hallazgos en otrosestudios y que presentan dificultades para su identificación. Tras eliminar pertinentemente seis elementos se obtuvo un coeficiente Alfa de Cronbach de 0,73 y un modelo de cuatro factores identificados como motivación, proyección, control percibido e ilusión, que explican el 55% de la varianza. Conclusión: Se concluye que la EDB modificada (14 elementos) presenta una consistencia interna y estructura factorial adecuada.


Objetive: To measure the internal consistency and formulate the factorial analysis of Beck's Hopelessness Scale inpostpartum adolescents. Method: An observational, analytic, transversal study was conducted. Between January and May 2010, we applied a survey in every postpartum adolescent attended at Instituto Nacional Materno Perinatal. The internal consistency was evaluated by Cronbach's alpha coefficient and the factorial structure by the main components extractionand varimax rotation. Results: Cronbach's alpha coefficient was 0.70. The factorial structure showed 6 components, which doesn't correlates with other studies' findings. After eliminating 6 elements from Beck's Hopelessness Scale, we got a Cronbach alpha coefficient of 0.733 and a factorial structure with 4 components, identified as Motivation, Projection, Perceived Control and Illusion, explaining 55% of variance. Conclusion: We concluded that the modified Beck's Hopelessness Scale has an adequate internal consistency and factorial structure.


Assuntos
Feminino , Ilusões , Motivação , Percepção , Psicometria , Estudos Transversais , Estudos Observacionais como Assunto
8.
Rev. latinoam. psicol ; Rev. latinoam. psicol;44(1): 55-63, Jan.-Apr. 2012. ilus
Artigo em Inglês | LILACS | ID: lil-657079

RESUMO

Este trabajo examina las nociones de ilusiones y creencias, discutiendo algunas ventajas que ofrece estudiar tales fenómenos basándose en los conceptos de conducta supersticiosa, superstición y reglas supersticiosas. El trabajo pone de relieve la posibilidad de investigar estas nociones en diferentes niveles de análisis, no sólo a nivel individual, centrándose en el nivel cultural; por otra parte, se presenta el Materialismo Cultural como una propuesta antropológica basada en principios adaptativos, la cual se adecua para tratar estos fenómenos en este nivel, además, discute el Análisis Experimental de las prácticas culturales y señala cómo estos análisis pueden ayudar a entender cómo la gente, en grupo, se comporta como si tuvieran control de su ambiente (cuando, a veces, de hecho, no lo tienen). Este trabajo ofrece una propuesta integradora que facilita el diálogo entre analistas de la conducta y psicólogos sociales y ofrece algunas rutas para un análisis cultural de las ilusiones y las creencias.


This paper examines the notions of illusions and beliefs, discussing some advantages offered by the study of these phenomena based on the concepts of superstitious behavior, superstition and superstitious rules. Among these advantages, the study highlights the possibility of researching these relationships in different levels of analysis, not only at the individual level, focusing on cultural level, this paper presents Cultural Materialism as an anthropological proposal for the consideration of these phenomena on the cultural level and based on adaptive principles, besides it discusses the experimental analysis of cultural practices and points out how they can help to understand how people in groups behave such as they are being effective in the control of the surrounding environment (when, sometimes, in fact, they are not). The paper offers an integrative proposal which makes easier behavior analysts' dialogue with social psychologists and offers some routes from cultural analysis of illusions and beliefs.

9.
J. bras. psiquiatr ; J. bras. psiquiatr;58(4): 223-230, 2009. tab, ilus
Artigo em Português | LILACS | ID: lil-543771

RESUMO

OBJETIVO: Descrever o desenvolvimento de um instrumento para identificar as recordações de pacientes internados em Unidade de Terapia Intensiva (UTI) e verificar a validade de conteúdo e a aplicabilidade do instrumento. MÉTODO: Estudo de desenvolvimento metodológico, fundamentado na teoria de elaboração de escalas psicológicas de Pasquali (1998). Para elaboração do instrumento, foram percorridas três etapas, a construção dos itens, a análise da validade de conteúdo e aparência por um painel de experts e, por fim, a realização de um estudo-piloto para verificar a aplicabilidade do instrumento na população-alvo. RESULTADOS: Houve pouca discordância entre os experts na análise das questões de acordo com os domínios do construto. Os itens foram avaliados positivamente, recebendo uma pontuação acima de 80 por cento, valor este que obedece ao critério de validação do instrumento. Dessa forma, os itens foram considerados consistentes em relação aos domínios e ao construto, possibilitando identificar recordações das experiências vividas pelos pacientes durante sua permanência em UTI. CONCLUSÕES: Os itens propostos mostraram-se compreensíveis, claros e com uma adequada estrutura de apresentação. O instrumento apresenta validade de conteúdo atestada por um painel de experts, demonstrando possuir características teóricas para identificar memórias de pacientes internados em UTI a curto e longo prazo.


OBJECTIVE: Describe the development of an instrument to identify records of their stay at the intensive care unit, and verify content validation and the applicability of the instrument. METHOD: It is a methodological study, based in Pasquali's (1998) psychological scale elaboration theory. To elaborate the instrument, three stages were followed: the built of items; appearance and content validation analysis performed by a panel of experts; together with implementation of a pilot study to validation instrument applicability in the targeted population. RESULTS: There was little unconformity among the experts when analyzing the questions according to the domain of the constructor. The items were positively evaluated having a punctuation value above 80 percent, which abides the instrument validation criteria. Thus, the items were considered consistent in relation to the domain and constructor allowing identification of recollection of memories lived by the patients during their stay at the ICU. CONCLUSIONS: The proposed items demonstrated to be comprehensive, clear, and having an adequate presentation structure. The instrument shows validation to the content certified by a panel of experts, thus demonstrating to have theoretical characteristics to identify short and long term recollections of ICU patients.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Unidades de Terapia Intensiva , Memória , Rememoração Mental , Pacientes Internados/psicologia , Brasil
10.
Gac. méd. Caracas ; 116(2): 152-160, jun. 2008. ilus
Artigo em Espanhol | LILACS | ID: lil-630534

RESUMO

La parapsicología se refiere al estudio de ciertos tipos de fenómenos paranormales. Paranormal conciernea una experiencia que no parece ser explicable en términos del conocimiento científico o de nuestra comprensión de hechos cotidianos. La realidad científica del fenómeno parapsicológico y la validez científica de sus investigaciones, a menudo son áreas de frecuente disputa y crítica. Hasta ahora la psicología formal la caracteriza como una pseudociencia. La palinopsia es un raro síntoma caracterizado por el fenómeno ilusorio de perseveración y/o recurrencia de imágenes visuales luego de haber sido removido el estímulo excitatorio. Es una distorsión del procesamiento de imágenes en el sistema visual causado por lesiones unilaterales o bilaterales de variado origen que afectan las áreas posteriores de los hemisferios cerebrales, toxicidad o efectos colaterales de drogas terapéuticas, una extensa lista de condiciones misceláneas y aún en sujetos normales. A despecho de su rareza, existe abundante literatura al respecto posiblemente por su carácter intrigante o por su naturaleza pseudo-parapsicológica. Los autores presentan los casos de 6 pacientes, dos de los cuales estaban recibiendo tamoxifeno, una droga hasta el presente no reconocida como causa de este fenómeno


Parapsychology is the scientific study of certain types of paranormal phenomena. The “paranormal” (beside or beyond the normal) refers to unusual experiences that do not seem to be explainable in terms of our everyday understanding or known scientific principles. The scientificreality of parapsychological phenomena and the validity of scientific parapsychological research is amatter of frequent dispute and criticism. The field is regarded by some critics as a pseudoscience. Palinopsia is a rare symptom characterized by the illusory phenomenon of perseverance or recurrence of visual images after removal of the exciting stimulus. It is a distortion of the processing in the visual system caused by unilateral o bilateral lesions of various kinds, such as toxicity or side effects of drugs, as well as an array of miscellaneous conditions, that affect posterior areas of the cerebral hemispheres in normal subjects. Despite its rarity, there is abundance of literature on the subject, possibly because of the intriguing, quasiparapsychologic nature of the symptom. Six patients were identified with the diagnosis of palinopsia o poliopsia of whom two were taking the drug tamoxifen not previously described in the literature


Assuntos
Humanos , Masculino , Adulto , Feminino , Pessoa de Meia-Idade , Idoso de 80 Anos ou mais , Carcinoma Pulmonar de Células não Pequenas/patologia , Meningioma/patologia , Metástase Neoplásica/patologia , Neoplasias da Mama/patologia , Neurocisticercose/patologia , Tamoxifeno/administração & dosagem , Imagens, Psicoterapia , Papiledema/etiologia , Tamoxifeno/farmacologia , Campos Visuais
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