RESUMO

Analysis of 27 rotavirus strains from vaccinated and unvaccinated children revealed reassortment events in 3 strains: a gene derived from a vaccine; a gene acquired from a circulating strain; and reassortment between circulating strains. Data suggest that the widespread use of this monovalent rotavirus vaccine may introduce vaccine genes into circulating human rotaviruses or vice versa.

Assuntos

Vírus Reordenados , Infecções por Rotavirus/epidemiologia , Infecções por Rotavirus/virologia , Vacinas contra Rotavirus/efeitos adversos , Rotavirus/genética , Rotavirus/imunologia , Brasil/epidemiologia , Genes Virais , Humanos , Dados de Sequência Molecular , Filogenia , Rotavirus/classificação , Infecções por Rotavirus/prevenção & controle , Vacinas contra Rotavirus/imunologia