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1.
Vet Res Commun ; 48(5): 3371-3374, 2024 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-39023847

RESUMO

Choloepus didactylus (two-toed sloth) is a Xenarthran mammal whose morphology has so far been little studied. Given the increasing number of sloths requiring clinical and surgical interventions, this lack of clarity regarding anatomical features and landmarks has had a negative impact on veterinary decision-making for this species. We therefore sought to describe the topography of the medullary cone (MC) of Choloepus didactylus in order to provide guidance to qualified professionals on the ideal access for locoregional anesthesia. In evaluating four specimens, radiographs and dissections revealed that Choloepus didactylus has three lumbar vertebrae and five sacral vertebrae. The lumbar intumescence is located between T14 and the cranial half of L2, the medullary cone is located between the caudal half of L2 and L3, with an average length of 2.26 cm, and the cauda equina extends from S1 to S5. Based on these anatomical findings, we propose that the lumbosacral region would be the most suitable target for epidural anesthesia in Choloepus didactylus.


Assuntos
Bichos-Preguiça , Animais , Bichos-Preguiça/anatomia & histologia , Masculino , Vértebras Lombares/anatomia & histologia , Vértebras Lombares/diagnóstico por imagem , Feminino , Anestesia Epidural/veterinária
2.
J ISAKOS ; 9(3): 334-340, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38460601

RESUMO

OBJECTIVE: Reconstructive surgery of the anterior cruciate ligament (ACL) is quite common, previous studies have documented that adequate pain control in the early phases of the postoperative period translates into early mobility and a rapid start of rehabilitation. Therefore, the search for new strategies for postoperative pain control is justified. The aim of this study was to compare intra-articular to the epidural administration of ropivacaine and midazolam as postoperative analgesia after arthroscopic ACL reconstruction with hamstring autograft (HA). MATERIAL AND METHODS: Double-blinded, prospective randomized clinical trial included 108 consecutive patients aged from 18 to 50 years that had undergone arthroscopic ACL reconstruction with HA. The patients were randomly assigned to 2 groups. The first group received intraarticular ropivacaine and midazolam. The second group received epidural ropivacaine and midazolam. The need for rescue analgesia, the postoperative pain experienced, side effects and complications of the analgesic drugs were evaluated. RESULTS: The intra-articular group received statistically significantly higher mean doses of rescue analgesia on the first two days (2.8 â€‹± â€‹1.0 vs. 1.3 â€‹± â€‹0.6 in the epidural group; p â€‹= â€‹0.001). Visual Analogue Scale scores at flexion were statistically significantly higher in the intra-articular group over the entire study period. The intra-articular group also reported a statistically significantly lower range-of-motion 87 â€‹± â€‹15 vs. 102 â€‹± â€‹11 in the epidural group (p â€‹= â€‹0.001). CONCLUSIONS: Epidural administration of ropivacaine combined with midazolam in patients undergoing primary ACL reconstruction with HA was clinically and significantly better relative to rescue analgesia and the intensity of pain in the first 48 postoperative hours when compared to intraarticular administration. There was no difference in terms of adverse effects and complications.


Assuntos
Anestésicos Locais , Reconstrução do Ligamento Cruzado Anterior , Artroscopia , Midazolam , Dor Pós-Operatória , Ropivacaina , Humanos , Ropivacaina/administração & dosagem , Ropivacaina/uso terapêutico , Adulto , Dor Pós-Operatória/tratamento farmacológico , Dor Pós-Operatória/prevenção & controle , Reconstrução do Ligamento Cruzado Anterior/métodos , Masculino , Feminino , Midazolam/administração & dosagem , Midazolam/uso terapêutico , Método Duplo-Cego , Pessoa de Meia-Idade , Estudos Prospectivos , Anestésicos Locais/administração & dosagem , Anestésicos Locais/uso terapêutico , Adolescente , Injeções Intra-Articulares , Artroscopia/métodos , Analgesia Epidural/métodos , Adulto Jovem , Amidas/administração & dosagem , Amidas/uso terapêutico , Medição da Dor , Autoenxertos , Resultado do Tratamento
3.
Res Vet Sci ; 168: 105115, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38199013

RESUMO

Veterinary care for rabbits has been growing, and, consequently, the anesthetic and analgesic management of this species must be improved. The aim of the present study was to evaluate the technique of localization of the epidural space with the aid of a peripheral nerve stimulator and epidurographic, comparing two techniques for determining the infused volume in rabbits (Oryctolagus Cuniculus). In a prospective, randomized blinded study, six healthy New Zealand rabbits, adults, and weighing from 2.2 kg to 3.8 kg received two treatments, at 1 week intervals: 0.33 mL/kg (treatment I) or 0.05 mL per centimeter of the spine (treatment II) of ioexol epidurally. In both treatments, a peripheral nerve stimulator (2 Hz, 0.25 mA and 0.1 milliseconds) was used to determine the location of the epidural space. Latero-lateral and ventro-dorsal radiographs were taken after five (T5) and twenty-five minutes (T25) of iohexol administration. The epidural space was correctly accessed in 92% of attempts. Treatment I received a smaller volume of contrast than treatment II, 1.0 ± 0.2 mL versus 2.1 ± 0.1 mL (mean ± standard deviation), respectively (p = 0.007). At T5, the cranial progression of the contrast varied between L4 and L5 in treatment I, and L5 and T10 in treatment II. At T25, no contrast was observed in any rabbit. In conclusion, peripheral nerve stimulator aided in accessing the lumbosacral epidural space, and the administration of 0.05 mL per centimeter of the spine resulted in greater cranial progression of contrast.


Assuntos
Espaço Epidural , Iohexol , Coelhos , Animais , Injeções Epidurais/veterinária , Injeções Epidurais/métodos , Estudos Prospectivos , Nervos Periféricos
4.
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1559775

RESUMO

Introducción: La utilidad de las técnicas de anestesia regional se ha mostrado por muchos años, estas son las de elección por los beneficios que aporta, como es el caso de la cesárea, aunque no están exentas de complicaciones, y las neurológicas que son las más temidas por la gravedad del cuadro clínico presentado y los posibles desenlaces. Objetivo: Describir la evolución clínica de la puérpera con diagnóstico de neumoencéfalo después de anestesia neuroaxial peridural. Presentación de caso: Se trata de una paciente puérpera con antecedente de cefalea migrañosa que después de ser sometida a una anestesia peridural, comienza con dolor de cabeza ligero a moderado que en un principio aliviaba con analgésicos, después hace una convulsión tónica clónico generalizada que fue necesaria intubar y trasladar a terapia intensiva. Mediante la tomografía axial computarizada se detecta neumoencéfalo de pequeñas proporciones en región parietal, además, de signos de edema cerebral, el cuadro evoluciona satisfactoriamente, la paciente a las horas es trasladad a sala donde se reencuentra con su bebe y días después es dada de alta sin secuelas. Conclusiones: El neumoencéfalo como complicación de la anestesia peridural en la paciente gestante, generalmente no tienen gran repercusión clínica y desaparece solo en un período no mayor de 72 horas, pero en ocasiones puede presentarse como complicación grave que puede acarrear daño neurológico permanente e incluso la muerte.


Introduction: Regional anesthesia techniques have been used for many years and there are surgeries where they are the ones of choice due to the proven benefits they provide, as is the case with anesthesia forces is a section, which is not free of complications, but the neurological ones are the ones. Most feared, due to the complexity of the situation and the possible outcomes they could entail. Objective: To describe the evolution of a postpartum patient who was diagnosed with Pneumocephalus after epidural anesthesia. Clinical case: Postpartum patient with a history of migraine headache, which after undergoing epidural anesthesia, began with light to moderate headache that was initially relieved with analgesics, then had a generalized tonic-clonic seizure that required intubation and transfer to the intensive therapy. Using computed axial tomography, small Pneumocephalus was detected in the parietal region in addition to signs of cerebral edema. The condition progressed satisfactorily. Within hours, the patient was transferred to the ward where she was reunited with her baby and day slater she was discharged without squeals. Conclusions: Pneumocephalus as a complication of epidural anesthesia in pregnant patients generally does not have great clinical repercussions and disappears only in a period of no more than 72 hours, but sometime sit can occur as a serious complication that can lead to permanent neurological damage and even death, death.

5.
Braz. J. Anesth. (Impr.) ; 73(2): 217-219, March-Apr. 2023. tab
Artigo em Inglês | LILACS | ID: biblio-1439596

RESUMO

Abstract Emery-Dreifuss Muscular Dystrophy is a very rare type of muscular dystrophy, associated with contractures, atrophy, and muscle weakness, besides cardiomyopathy with severe arrhythmias. Published studies focusing on this disorder are scarce. We describe the anesthetic management of a male patient with Emery-Dreifuss Muscular Dystrophy, to be submitted to umbilical and inguinal hernioplasty and hydrocele repair under epidural anesthesia. The anesthesia approach enabled us to circumvent the patient's susceptibility to malignant hyperthermia and his potentially difficult airway, in addition to maintaining hemodynamic stability. The day after surgery the patient resumed walking, and two days later he was discharged from the hospital.


Assuntos
Humanos , Masculino , Distrofia Muscular de Emery-Dreifuss/complicações , Distrofia Muscular de Emery-Dreifuss/patologia , Anestesia Epidural , Anestésicos , Hipertermia Maligna
6.
Rev. mex. anestesiol ; 46(1): 67-72, ene.-mar. 2023. graf
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1450138

RESUMO

Resumen: Pocas han sido las Figuras españolas que han aportado alguna interesante novedad al mundo de la anestesia, pero ninguna tan injustamente tratada y olvidada como la de Pagés, verdadero pionero de la anestesia epidural, que él denominaría «anestesia metamérica¼ en su artículo publicado en el mes de marzo de 1921 en la Revista Española de Cirugía, fundada por él mismo. Años después, en 1931, Dogliotti, profesor de Cirugía de Módena publicó sus experiencias sobre la anestesia epidural, a la que llamó «anestesia peridural segmentaria¼, ignorando el trabajo de Pagés publicado 10 años antes. El trabajo de Dogliotti fue rápidamente reconocido, asumiendo todos los méritos de la paternidad de la técnica epidural, quedando Pagés relegado a un olvido injusto que con este trabajo tratamos de reparar. La idea central de este texto versará sobre el reconocimiento de Pagés como verdadero promotor del abordaje epidural con fines quirúrgicos. Destacar sus ideas innovadoras sobre el bienestar del paciente y la minimización de los efectos adversos de las técnicas anestésicas y quirúrgicas, así como valorar una obra que, aunque corta, bien podría incluirse entre los mejores cirujanos españoles de principio del siglo XX, un cirujano con alma de anestesiólogo.


Abstract: Few Spanish Figures have contributed any interesting novelty to the world of anesthesia. But none so unjustly treated and forgotten such as Pagés, a true pioneer of epidural anesthesia, which he would call «metameric anesthesia¼ in his article published in March 1921 in the Spanish Journal of Surgery, founded by himself. Later, in 1931, Dogliotti, Modena Professor of Surgery published his experiences on epidural anesthesia, which he called «segmental peridural anesthesia¼, ignoring Pagés work published 10 years earlier. Dogliotti's work was quickly recognized, assuming all the merits of the paternity of the epidural technique, leaving Pagés relegated to an unjust oblivion that with this work we try to repair. The central idea of this text will focus on the recognition of Pagés as a true promoter of the epidural approach for surgical purposes. Highlight his innovative ideas about patient well-being and minimizing the adverse effects of anesthetic and surgical techniques. As well as assessing a work that, although short, could well be included among the best Spanish surgeons of the early twentieth century, a surgeon with the soul of an anesthesiologist.

7.
Braz J Anesthesiol ; 73(4): 506-509, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-35296426

RESUMO

Impediment to local anesthetic solution in the epidural space results in unsatisfactory pain relief during labor epidural. Patients with a history of back trauma and spinal instrumentation have increased rates of epidural failure due to patchy spread of local anesthetic with obliterated epidural space. Dual Epidural Catheters (DEC) can be used in such clinical scenarios with complete labor analgesia and improved patient satisfaction. We present the successful management of a parturient with vertebral fracture at risk for epidural failure and neurologic injury due to bone fragments and inserted cranial and caudal to the fractured vertebra using ultrasound to avoid neurologic sequelae.


Assuntos
Analgesia Epidural , Analgesia Obstétrica , Anestesia Epidural , Traumatismos da Medula Espinal , Humanos , Anestésicos Locais , Analgésicos , Catéteres , Analgesia Obstétrica/métodos
8.
Braz J Anesthesiol ; 73(2): 217-219, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-34624368

RESUMO

Emery-Dreifuss Muscular Dystrophy is a very rare type of muscular dystrophy, associated with contractures, atrophy, and muscle weakness, besides cardiomyopathy with severe arrhythmias. Published studies focusing on this disorder are scarce. We describe the anesthetic management of a male patient with Emery-Dreifuss Muscular Dystrophy, to be submitted to umbilical and inguinal hernioplasty and hydrocele repair under epidural anesthesia. The anesthesia approach enabled us to circumvent the patient...s susceptibility to malignant hyperthermia and his potentially difficult airway, in addition to maintaining hemodynamic stability. The day after surgery the patient resumed walking, and two days later he was discharged from the hospital.


Assuntos
Anestesia Epidural , Anestésicos , Hipertermia Maligna , Distrofia Muscular de Emery-Dreifuss , Humanos , Masculino , Distrofia Muscular de Emery-Dreifuss/complicações , Distrofia Muscular de Emery-Dreifuss/patologia
9.
Braz. J. Anesth. (Impr.) ; 73(4): 506-509, 2023. graf
Artigo em Inglês | LILACS | ID: biblio-1447627

RESUMO

Abstract Impediment to local anesthetic solution in the epidural space results in unsatisfactory pain relief during labor epidural. Patients with a history of back trauma and spinal instrumentation have increased rates of epidural failure due to patchy spread of local anesthetic with obliterated epidural space. Dual Epidural Catheters (DEC) can be used in such clinical scenarios with complete labor analgesia and improved patient satisfaction. We present the successful management of a parturient with vertebral fracture at risk for epidural failure and neurologic injury due to bone fragments and inserted cranial and caudal to the fractured vertebra using ultrasound to avoid neurologic sequelae.


Assuntos
Humanos , Traumatismos da Medula Espinal , Analgesia Epidural , Anestesia Epidural , Analgesia Obstétrica/métodos , Catéteres , Analgésicos , Anestésicos Locais
10.
Braz J Anesthesiol ; 72(2): 267-273, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-33814226

RESUMO

OBJECTIVES: This study was to compare the effects of different local analgesia protocols on osteoarthritis patients undergoing total knee arthroplasty (TKA). METHODS: Medical records of 148 osteoarthritis patients who underwent unilateral TKA between October 2016 and October 2017 in our hospital were retrospectively analyzed. All these patients were divided into three groups according to the pain management protocol (morphine, morphine + cocktail [100 mg ropivacaine, 10 mg morphine, and 30 mL 0.9% sodium chloride solution containing 2 mL betamethasone (4 mg)], or cocktail). The postoperative visual analog scale (VAS) score, muscle strength, and complications were compared between the groups. RESULTS: At 6 and 12 hours post-operation, the VAS score in group C was significantly higher than that in group A or group B. In addition, the muscle (quadriceps femoris) strength score of group C (3.7 ± 2.8) was significantly higher than that in groups A and B at 6 and 12 hours post-operation. The VAS score and muscle strength score showed no significant differences among the three groups at 24 and 36 hours post-operation. The time of postoperative first void of group C was significantly shorter than that of groups A and B. Groups A or B had a significantly higher incidence of nausea and emesis compared with group C. The incidence of pruritus was higher in groups A or B than that in group C. CONCLUSION: Epidural anesthesia combined with local analgesic cocktail injection is a preferable effective multimodal analgesia for TKA.


Assuntos
Analgesia , Artroplastia do Joelho , Osteoartrite , Analgésicos Opioides , Anestésicos Locais , Artroplastia do Joelho/efeitos adversos , Método Duplo-Cego , Humanos , Morfina , Osteoartrite/complicações , Manejo da Dor , Dor Pós-Operatória/tratamento farmacológico , Dor Pós-Operatória/etiologia , Dor Pós-Operatória/prevenção & controle , Estudos Retrospectivos
11.
Ginecol. obstet. Méx ; Ginecol. obstet. Méx;90(8): 682-687, ene. 2022.
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1404959

RESUMO

Resumen ANTECEDENTES: La enfermedad de Arnold-Chiari es una malformación congénita rara del sistema nervioso central, caracterizada por el descenso del cerebelo por debajo de 5 mm del nivel del foramen magno, con o sin siringomielia asociada (tipos I o II). La edad media a la que se detecta la enfermedad tipo I son los 40 años. Es más frecuente en mujeres con una relación 3:1. Sus manifestaciones son: cefalea occipital (70-90%), dolor neuropático de segmentos cervicales (40-70%); hiperreflexia de extremidades inferiores (51%); atrofia de manos (35%) y paresias de extremidades superiores (35%) e inferiores (17%). El diagnóstico se establece con base en la resonancia magnética. OBJETIVO: Analizar el comportamiento anestésico-obstétrico en una paciente embarazada y el riesgo de complicaciones derivadas de los cambios fisiológicos y de la gestación. CASO CLÍNICO: Paciente de 30 años, con 38 semanas de embarazo y diagnóstico de enfermedad de Arnold-Chiari tipo I, con adecuado control neurológico y obstétrico y evolución satisfactoria. El embarazo finalizó por parto. CONCLUSIONES: La atención médica a la paciente del caso fue adecuada porque no se registraron complicaciones y fue posible darle el alta del hospital en muy poco tiempo.


Abstract BACKGROUND: Arnold-Chiari disease is a rare congenital malformation of the central nervous system, characterized by descent of the cerebellum below 5 mm from the level of the foramen magnum, with or without associated syringomyelia (types I or II). The average age at which type I disease is detected is 40 years. It is more frequent in women with a 3:1 ratio. Its manifestations are occipital headache (70-90%), neuropathic pain of cervical segments (40-70%); hyperreflexia of lower extremities (51%); atrophy of hands (35%) and paresis of upper (35%) and lower extremities (17%). Diagnosis is established based on magnetic resonance imaging. OBJECTIVE: To analyze the anesthetic-obstetric behavior in a pregnant patient and the risk of complications derived from physiological and gestational changes. CLINICAL CASE: 30-year-old patient, 38 weeks pregnant and diagnosed with Arnold-Chiari disease type I, with adequate neurological and obstetric control and satisfactory evolution. The pregnancy was terminated by delivery. CONCLUSIONS: The medical care of the patient in the case was adequate because no complications were recorded, and it was possible to discharge her from the hospital in a very short time.

12.
Rev Colomb Obstet Ginecol ; 72(3): 258-270, 2021 09 30.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-34851569

RESUMO

Objective: To describe the clinical characteristics and the frequency of maternal, fetal and neonatal complications in accordance with the neuraxial anesthesia (NA) technique in women with twin-totwin transfusion syndrome (TTTS) treated with laser photocoagulation. Materials and Methods: Descriptive retrospective cohort study of pregnant patients with TTTS treated with laser photocoagulation under NA at Fundación Valle del Lili, Cali (Colombia), between 2013-2017. Patients with Quintero stage V TTTS were excluded. The protocol was approved by the institutional ethics committee. Results: Of the participants, 32 met the inclusion and exclusion criteria. The study population consisted of young, multiparous women. Urgent interventions were performed in 87.5% of cases; 43.7% were Quintero stage III and epidural anesthesia was used in 56.2% of the women. Maternal hemodynamic variables were similar, in accordance with the timing of surgery and the neuraxial technique used. Sustained hypotension occurred in 65.6% of the pregnant women and 9.3% developed pulmonary edema. Pre-term delivery occurred in 65.6% of the patients and 18.7% had premature rupture of membranes. There were 14 fetal demises and five neonatal deaths. There were no cases of maternal mortality. Conclusions: In patients with TTTS requiring laser photocoagulation, the use of epidural, spinal or combined anesthesia is likely associated with similar maternal hemodynamic variables at the time of surgery. Practitioners providing care to these pregnant women must be aware of the frequent occurrence of maternal, fetal and neonatal complications. Prospective studies to assess the safety and effectiveness of the different neuraxial anesthesia techniques in patients with TTTS are required.


Objetivo: describir las características clínicas y la frecuencia de complicaciones maternas, fetales y neonatales, según técnica de anestesia neuroaxial (AN) en mujeres con síndrome de transfusión feto-fetal (STFF) tratadas con fotocoagulación láser (FL). Materiales y métodos: estudio de cohorte retrospectiva descriptivo. Se incluyeron gestantes con STFF tratadas con FL y AN en la Fundación Valle del Lili, Cali (Colombia) entre 2013-2017. Se excluyeron pacientes con STFF estadio-V de Quintero. Se usó estadística descriptiva. El protocolo fue aprobado por el Comité de Ética de la institución. Resultados: 32 participantes cumplieron con los criterios de inclusión y de exclusión. La población estuvo constituida por mujeres jóvenes, multíparas. En el 87,5% de los casos se realizó intervención de urgencia. El 43,7% presentaba el estadio-III de Quintero y en el 56,2 % de las gestantes se utilizó anestesia epidural. Las variables hemodinámicas maternas exhibieron un comportamiento similar, acorde al momento de la cirugía y la técnica neuoraxial implementada. El 65,6 % de las gestantes presentó hipotensión sostenida y el 9,3 % desarrolló edema pulmonar. El 65,6 % de las pacientes experimentó parto pretérmino y el 18,7 % ruptura prematura de membranas. Se registraron 14 muertes fetales y cinco neonatales. No se registraron casos de mortalidad materna. Conclusiones: en pacientes con STFF que requieren FL, el uso de la anestesia epidural, espinal o combinada probablemente se asocia con un comportamiento similar al de las variables hemodinámicas maternas, durante los momentos de la cirugía. Los profesionales que brindan atención a estas gestantes deben estar alerta ante la frecuente aparición de complicaciones maternas, fetales y neonatales. Se requieren estudios prospectivos que evalúen la seguridad y la efectividad de las diferentes técnicas de anestesia neuroaxial en pacientes con STFF.


Assuntos
Anestesia Epidural , Transfusão Feto-Fetal , Anestesia Epidural/efeitos adversos , Feminino , Transfusão Feto-Fetal/cirurgia , Fetoscopia/efeitos adversos , Idade Gestacional , Humanos , Fotocoagulação a Laser , Lasers , Gravidez , Gravidez de Gêmeos , Estudos Prospectivos , Estudos Retrospectivos
13.
Rev. argent. radiol ; 85(4): 91-97, dic. 2021. tab, graf
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1356979

RESUMO

Resumen Objetivo. Establecer la relación entre la reducción inmediata de los síntomas post bloqueo nervioso lumbar guiado por tomografía computada (TC) y la mejoría tras un lapso de tiempo de un mes. Materiales y métodos. Se analizaron datos sobre 46 procedimientos de bloqueos lumbares radiculares y epidurales guiados por TC realizados entre diciembre de 2018 y marzo de 2019. Los pacientes firmaron consentimiento informado y el Comité de Ética en Investigación de nuestra institución aprobó el estudio. Se colectó, mediante un cuestionario dicotómico, información acerca de los síntomas iniciales, los cambios inmediatos al procedimiento y los síntomas tras un mes del mismo. Resultados. Inmediatamente post-bloqueo, 30 pacientes (65%) mostraron mejoría o ausencia de síntomas y seis de ellos manifestaron persistencia de los síntomas al mes. Post-procedimiento inmediato, 16 pacientes (34%) no presentaron ningún cambio en la sintomatología. De estos, siete presentaron mejoría al mes. La razón de momios para la persistencia del efecto analgésico al mes en los casos en los que el paciente manifestó alivio inmediato después del procedimiento fue de 5,1 (95% IC 1.128 a 24.031). La prueba de McNemar para determinar si esta diferencia en la proporción de pacientes con alivio inmediatoposterioralapunciónypersistenciadelefectoanalgésicoarrojóunpvaluede0,08. Conclusión. Existió asociación positiva entre la mejoría inmediata y la ausencia de síntomas al mes. Sin embargo, el análisis estadístico de antes y después insinúa que estos resultados pudieron ser por el azar.


Abstract Objective. To establish the relationship between the immediate symptom reduction of post-lumbar nerve block guided by Computed Tomography (CT) and the improvement after a period of one month. Materials and methods. Data from 46 patients who performed lumbar, foraminal and epidural CT-guided blocks were analyzed, performed from December 2018 to March 2019. The patients signed a written informed consent and our institutional Ethical Committee approved the study. By means of a dichotomous questionnaire, information was collected about the initial symptoms, the immediate changes after the procedure and the presence of symptoms one month later. Results. Immediately after blockade, 30 patients (65%) showed improvement or absence of symptoms six of them manifested persistence of symptoms after a month. Immediately after the procedure, 16 (34%) patients did not present any change in the symptomatology. Seven of them showed improvement after a month. Odds ratio for persistence of analgesic effect after a month when the patient had manifested immediate relief after procedure was 5.1 (95% IC 1.128-24.031). Nevertheless, exact Mc Nemar's test to establish statistically significant difference in patients with immediate relief and those with persistence of it after a month showed a p value of 0.08. Conclusion. There was a positive association between immediate and midterm symptom relief, however before and after statistical analysis hints that this results may have been given by chance.

14.
Rev. cuba. anestesiol. reanim ; 20(3): e743, 2021. graf
Artigo em Espanhol | LILACS, CUMED | ID: biblio-1351990

RESUMO

Introducción: La anestesia epidural lumbar es la técnica predilecta para gran número de anestesiólogos. Permite variadas intervenciones quirúrgicas, es útil para el tratamiento del dolor agudo y crónico, a la vez provee al paciente de distintos beneficios. También resalta su versatilidad ya que puede combinarse con otros métodos anestésicos, así como extenderla para el alivio del dolor posoperatorio. Objetivo: Describir los adelantos científicos que propiciaron la aparición de la anestesia epidural lumbar y cuál ha sido la evolución de esta técnica anestésica a lo largo de un siglo. Desarrollo: El acceso por vía lumbar al espacio epidural con fines anestésicos fue publicado por el cirujano español Fidel Pagés en marzo de 1921, luego de una década en el olvido fue introducida por el cirujano italiano Archile Dogliotti en 1931. A partir de entonces, se le han incorporado diversos y valiosos adelantos. Conclusiones: La anestesia epidural lumbar fue descrita hace un siglo por el doctor Pagés. Han sido variados y numerosos los aportes que han recibido, algunos de los cuales han sido objeto de controversias; no obstante, se ha tornado una técnica universal que sigue captando la preferencia de muchos anestesiólogos(AU)


Introduction: Lumbar epidural anesthesia is the technique preferred by a great number of anesthesiologists. It allows performing several surgical interventions and is useful for the treatment of acute and chronic pain; at the same time, it provides the patient with different benefits. It ls also worth highlighting its versatility, since it can be combined with other anesthetic methods, as well as to be extended for postoperative pain relief. Objective: To describe the scientific advances that led to the appearance of lumbar epidural anesthesia and what has been the evolution of this anesthetic technique over a century. Development: the Spanish surgeon Fidel Pagés published lumbar access to the epidural space for anesthetic purposes in March 1921. After a decade in oblivion, the Italian surgeon Archile Dogliotti introduced it, in 1931. From then on, it has been incorporated several valuable advances. Conclusions: Dr. Pagés described lumbar epidural anesthesia a century ago. The contributions achieved have been varied and numerous, some of which have been the subject of controversy; however, it has become a universal technique that continues to capture the preference of many anesthesiologists(AU)


Assuntos
Humanos , Anestesia Epidural/história , Anestesiologistas/normas
15.
Rev. colomb. anestesiol ; 49(3): e602, July-Sept. 2021. tab, graf
Artigo em Inglês | LILACS, COLNAL | ID: biblio-1280185

RESUMO

Abstract Radical penectomy (RP) is infrequently performed as it is reserved for specific cases of penile cancer, hence the paucity of reports regarding surgical and anesthetic considerations. Acute postoperative pain, chronic post-surgical pain, concomitant mood disorders as well as a profound impact on the patient's quality of life have been documented. This case is of a patient with diabetes and coronary heart disease, who presented with advanced, over infected penile cancer, depressive disorder and a history of pain of neuropathic characteristics. The patient underwent radical penectomy using a combined spinal-epidural technique for anesthesia. Preoperatively, the patient was treated with pregabalin and magnesium sulphate, and later received a blood transfusion due to intraoperative blood loss. Adequate intra and postoperative analgesia was achieved with L-bupivacaine given through a peridural catheter during one week. Recovery was good, pain was stabilized to preoperative levels and the patient received pharmacological support and follow-up by psychiatry and the pain team.


Resumen La penectomía radical (PR) es una cirugía infrecuente, reservada para casos específicos de cáncer de pene, por lo que hay escasos informes sobre sus consideraciones quirúrgicas y anestésicas. Se ha documentado dolor agudo postoperatorio, dolor crónico posquirúrgico y alteraciones del estado de ánimo concomitantes, así como un profundo impacto en la calidad de vida posterior del paciente. Se presenta el caso de un paciente diabético y cardiópata coronario con cáncer de pene avanzado y sobreinfectado, trastorno depresivo y dolor previo de características neuropáticas, que recibe técnica combinada espinal-peridural para cirugía de penectomía radical. Se le trata también con pregabalina preoperatoria, sulfato de magnesio y transfusión por sangrado quirúrgico. Se otorgó una adecuada analgesia intra y postoperatoria, mediante catéter peridural con L-bupivacaína hasta por una semana. El paciente tuvo una buena recuperación, estabilización del dolor a niveles preoperatorios, controles y apoyo farmacológico por psiquiatría de enlace y equipo del dolor.


Assuntos
Humanos , Masculino , Idoso , Neoplasias Penianas , Neoplasias Penianas/cirurgia , Catéteres , Anestésicos , Dor Pós-Operatória , Psiquiatria , Qualidade de Vida , Transfusão de Sangue , Bupivacaína , Doença das Coronárias , Transtorno Depressivo , Manejo da Dor , Analgesia , Anestesia , Sulfato de Magnésio
16.
Rev. colomb. obstet. ginecol ; 72(3): 258-270, July-Sept. 2021. tab, graf
Artigo em Espanhol | LILACS | ID: biblio-1351951

RESUMO

Objetivo: describir las características clínicas y la frecuencia de complicaciones maternas, fetales y neonatales, según técnica de anestesia neuroaxial (AN) en mujeres con síndrome de transfusión feto-fetal (STFF) tratadas con fotocoagulación láser (FL). Materiales y métodos: estudio de cohorte retrospectiva descriptivo. Se incluyeron gestantes con STFF tratadas con FL y AN en la Fundación Valle del Lili, Cali (Colombia) entre 2013-2017. Se excluyeron pacientes con STFF estadio-V de Quintero. Se usó estadística descriptiva. El protocolo fue aprobado por el Comité de Ética de la institución. Resultados: 32 participantes cumplieron con los criterios de inclusión y de exclusión. La población estuvo constituida por mujeres jóvenes, multíparas. En el 87,5% de los casos se realizó intervención de urgencia. El 43,7% presentaba el estadio-III de Quintero y en el 56,2 % de las gestantes se utilizó anestesia epidural. Las variables hemodinámicas maternas exhibieron un comportamiento similar, acorde al momento de la cirugía y la técnica neuoraxial implementada. El 65,6 % de las gestantes presentó hipotensión sostenida y el 9,3 % desarrolló edema pulmonar. El 65,6 % de las pacientes experimentó parto pretérmino y el 18,7 % ruptura prematura de membranas. Se registraron 14 muertes fetales y cinco neonatales. No se registraron casos de mortalidad materna. Conclusiones: en pacientes con STFF que requieren FL, el uso de la anestesia epidural, espinal o combinada probablemente se asocia con un comportamiento similar al de las variables hemodinámicas maternas, durante los momentos de la cirugía. Los profesionales que brindan atención a estas gestantes deben estar alerta ante la frecuente aparición de complicaciones maternas, fetales y neonatales. Se requieren estudios prospectivos que evalúen la seguridad y la efectividad de las diferentes técnicas de anestesia neuroaxial en pacientes con STFF.


Objective: To describe the clinical characteristics and the frequency of maternal, fetal and neonatal complications in accordance with the neuraxial anesthesia (NA) technique in women with twin-to- twin transfusion syndrome (TTTS) treated with laser photocoagulation. Materials and Methods: Descriptive retrospective cohort study of pregnant patients with TTTS treated with laser photocoagulation under NA at Fundación Valle del Lili, Cali (Colombia), between 2013-2017. Patients with Quintero stage VTTTS were excluded. The protocol was approved by the institutional ethics committee. Results: Of the participants, 32 met the inclusion and exclusion criteria. The study population consisted of young, multiparous women. Urgent interventions were performed in 87.5% of cases; 43.7% were Quintero stage III and epidural anesthesia was used in 56.2% of the women. Maternal hemodynamic variables were similar, in accordance with the timing of surgery and the neuraxial technique used. Sustained hypotension occurred in 65.6% of the pregnant women and 9.3% developed pulmonary edema. Pre-term delivery occurred in 65.6% of the patients and 18.7% had premature rupture of membranes. There were 14 fetal demises and five neonatal deaths. There were no cases of maternal mortality. Conclusions: In patients with TTTS requiring laser photocoagulation, the use of epidural, spinal or combined anesthesia is likely associated with similar maternal hemodynamic variables at the time of surgery. Practitioners providing care to these pregnant women must be aware of the frequent occurrence of maternal, fetal and neonatal complications. Prospective studies to assess the safety and effectiveness of the different neuraxial anesthesia techniques in patients with TTTS are required.


Assuntos
Feminino , Gravidez , Recém-Nascido , Transfusão Feto-Fetal , Gravidez de Gêmeos , Anestesia Epidural , Raquianestesia , Segurança , Síndrome , Fotocoagulação a Laser , Fetoscopia , Anestesia
17.
Braz J Anesthesiol ; 71(2): 129-136, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33894856

RESUMO

BACKGROUND AND OBJECTIVES: The aim of this prospective, multi-centered and multi-arm parallel randomized trial was to test the hypothesis that modified sitting positions including hamstring stretch position (HSP) and squatting position (SP) would reduce needle - bone contact events and increase the success rate of combined spinal - epidural anesthesia (CSEA) compared to traditional sitting position (TSP) in patients undergoing total knee or hip arthroplasty. PATIENTS AND METHODS: Three hundred and sixty American Society of Anesthesiologists (ASA) I-III patients, aged between 45-85 years were randomly allocated to one of three groups using computer-generated simple randomization: group TSP (n = 120), group HSP (n = 120), and group SP (n = 120). Primary outcome measures were the number of needle-bone contact and success rates. Secondary outcome measure was the ease of interspinous space identification. RESULTS: Seven patients in group SP and four of HSP could not tolerate their position and were excluded. Number of needle-bone contact, success rates, and grade of interspinous space identification were similar between groups (p = 1.000). Independent of positioning, the success rates were higher in patients whose interspinous space was graded as easy compared to difficult or impossible (p < 0.001). Success rates reduced, interspinous space identification became more challenging, and number of needle - bone contact increased as patient's body mass index (BMI) increased (p < 0.001). CONCLUSION: SP and HSP may be used as alternatives to the TSP. BMI and ease of interspinous space identification may be considered important determinants for CSEA success.


Assuntos
Anestesia Epidural , Raquianestesia , Artroplastia de Quadril , Artroplastia do Joelho , Idoso , Idoso de 80 Anos ou mais , Espaço Epidural , Humanos , Pessoa de Meia-Idade , Estudos Prospectivos , Postura Sentada
18.
Braz J Anesthesiol ; 71(1): 31-37, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33712249

RESUMO

BACKGROUND AND OBJECTIVES: Epidural Volume Extension (EVE) involves instillation of normal saline into the epidural space soon after an intrathecal injection, with the aim to augment the sensory block height. Its clinical relevance lies in the possibility of using reduced intrathecal dose and yet achieving the desired sensory block level. Intrathecal dose is a known determinant of the level of sensory block. Whether EVE is dependent on intrathecal dose is not known. METHODS: We conducted a randomized, controlled, double-blind study to compare the maximum sensory level (Smax) achieved with or without application of EVE to two different reduced intrathecal doses. Eighty four adult male patients of ASA status I or II with body weight between 50-70kg and height in the range of 150-180cm, scheduled for orthopedic lower limb surgery using combined spinal epidural anesthesia were randomized to receive, either intrathecal dose (5 or 8mg) with or without EVE, in accordance to group allocation. RESULTS: Smax was lowered by application of EVE to 5mg intrathecal bupivacaine (T8.9±4.3 vs. T6.4±1.9 with and without EVE respectively; p = 0.030). Smax was similar when EVE was applied to 8mg intrathecal bupivacaine than without it (T5.8±1.8 vs. T6.4±2.2 respectively; p= 0.324). CONCLUSION: EVE should not be applied to 5mg plain bupivacaine during a combined spinal epidural block in patients undergoing lower limb orthopedic surgery as it may result in a decrease in the maximum sensory level.


Assuntos
Anestesia Epidural , Raquianestesia , Adulto , Anestésicos Locais , Bupivacaína , Cesárea , Método Duplo-Cego , Espaço Epidural , Feminino , Humanos , Masculino , Gravidez
19.
Braz J Anesthesiol ; 71(4): 454-457, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33762192

RESUMO

BACKGROUND AND OBJECTIVES: Neuraxial hematoma is a rare complication of the epidural technique which is commonly used for high quality postoperative pain relief. In case of urgent initiation of multiple antithrombotic therapy, the optimal timing of epidural catheter removal and need for treatment modification may be quite challenging. There are no specific guidelines and published reports are scarce. CASE REPORT: We present the uneventful removal of an indwelling epidural catheter in a patient who was put on emergency triple antithrombotic treatment with Low Molecular Weight Heparin (LMWH), aspirin and clopidogrel in the immediate postoperative period, due to acute coronary syndrome. In order to define the optimal conditions and timing for catheter removal, so as to reduce the risk of complications, various laboratory tests were conducted 3 hours after aspirin/clopidogrel intake. Standard coagulation tests revealed normal platelet count, normal prothrombin time and normal activated partial thromboplastin time, while Platelet Function Analysis (PFA-200) revealed abnormal values (increased COL/EPI and COL/ADP values, both indicating inhibition of platelet function). The anti-Xa level, estimated 4 hours after LMWH administration, was within therapeutic range. At the same time, Rotational Thromboelastometry (ROTEM) showed a relatively satisfactory coagulation status overall. The epidural catheter was removed 26 hours after the last dual antiplatelet dose and the next dose was given 2 hours after removal. Enoxaparin was withheld for 24 hours and was resumed after 6 hours. Neurologic checks were performed regularly for alarming signs and symptoms suggesting development of an epidural hematoma. No complications occurred. CONCLUSION: Point-of-care coagulation and platelet function monitoring may provide a helpful guidance in order to define the optimal timing for catheter removal, so as to reduce the risk of complications. A case-specific management plan based on a multidisciplinary approach is also important.


Assuntos
Síndrome Coronariana Aguda , Fibrinolíticos , Síndrome Coronariana Aguda/terapia , Catéteres , Fibrinolíticos/uso terapêutico , Heparina de Baixo Peso Molecular , Humanos , Período Pós-Operatório
20.
Braz. j. vet. res. anim. sci ; 58: e180388, 2021. ilus
Artigo em Inglês | VETINDEX | ID: vti-31677

RESUMO

A clinical case in which skin and hair color change occurred after sacrococcygeal epidural anesthesia in a nine-month-old Siamese cross queen undergoing ovariohysterectomy (OHE) is described. Six weeks after surgery, during a re-check, it was noted that in the sacrococcygeal region the color of the skin and new hair growth was dark with a color comparable to the color present on the body extremities (muzzle, pinnae, legs, and tail). The skin and new hair growth of the shaved abdomen presented a standard color. The key enzyme of the melanogenic pathway in mammals is tyrosinase (TYR), and the Siamese temperature-sensitive phenotype is the result of genetic mutations that makes TYR function thermolabile. The activity of TYR in these cats is limited to the extremities where the temperature is lower while pigment production is impaired in the other body areas. The trichotomy of the sacrococcygeal region performed during wintertime in an outdoor cat was probably the trigger for increased activity of TYR in this area promoting pigment production. The absence of the same alterations in the abdominal area may be justified by less exposure of that region to the external environment, as well as to the feline habits of sedentarism, that avoid significant cooling in these regions. This report highlights the importance of taking this type of occurrence into account when performing an epidural in the Siamese cat breed. Also, to avoid skin color change in this breed, the authors recommend a midline abdominal instead of a flank approach to perform OHE.(AU)


Descreve-se um caso clínico no qual ocorreu mudança na cor da pele e do pelo após anestesia epidural sacrococcígea numa gata cruzada de raça Siamês de nove meses submetida à ovariohisterectomia (OVH). Seis semanas após a cirurgia, durante uma avaliação pós-operatória, notou-se que na região sacrococcígea, a cor da pele e o crescimento do pelo apresentavam uma cor escura, comparável à das extremidades do corpo (face, orelhas, membros e cauda). A pele e o crescimento do pelo do abdómen, que também havia sido tosquiado, apresentavam uma cor padrão. A enzima chave da via melanogênica em mamíferos é a tirosinase (TYR) e o fenótipo siamês sensível à temperatura é o resultado de mutações genéticas que tornam a função TYR termolábil. A atividade da TYR nestes gatos é limitada às extremidades onde a temperatura é mais baixa, enquanto a produção de pigmento é prejudicada em outras áreas do corpo. A tricotomia da região sacrococcígea realizada durante o inverno nesta gata com acesso livre ao ambiente externo, provavelmente determinou um aumento da atividade da TYR nesta área, promovendo a produção de pigmento. A ausência das mesmas alterações na região abdominal pode ser justificada pela menor exposição desta área do corpo ao ambiente externo, também devido aos hábitos felinos de sedentarismo, que evitam resfriamento significativo nestas regiões. Este relato destaca a importância de se levar em consideração a possibilidade deste tipo de ocorrência quando da realização de uma anestesia epidural nesta raça de gatos. Além disso, os autores recomendam uma abordagem abdominal na linha média ao invés de uma abordagem de flanco para realizar a OVH nesta raça, a fim de evitar a alteração da cor da pele.(AU)


Assuntos
Animais , Gatos , Gatos , Técnicas de Laboratório Clínico , Anestesia Epidural/veterinária , Região Sacrococcígea , Remoção de Cabelo
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