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1.
Gastroenterol. latinoam ; 35(2): 64-68, 2024. ilus, tab
Artigo em Espanhol | LILACS | ID: biblio-1568194

RESUMO

Upper gastrointestinal symptoms affect 10% of the population, leading to significant costs and negatively impacting quality of life. Diagnosing disorders such as functional dyspepsia and gastroparesis is challenging due to overlapping symptoms. Gastric emptying scintigraphy (GES) has reproducibility issues. Body Surface Gastric Mapping (BSGM) is an advanced technique for precise and reliable electrophysiological mapping, overcoming the limitations of electrogastrography (EGG). Gastric Alimetry® measures gastric myoelectric potentials, providing valuable diagnostic data. BSGM uses an electrode array to capture gastric activity and requires a standardized protocol for comparable data. The metrics generated help identify specific gastric dysfunction phenotypes, improving diagnostic accuracy. These advancements promise to revolutionize the clinical management of chronic gastric symptoms, making this review essential reading for those interested in gastrointestinal research and treatment.


Los síntomas gastroduodenales afectan a más del 10% de la población, causando costos significativos e impac- tando negativamente la calidad de vida. Diagnosticar trastornos como la dispepsia funcional y la gastroparesia es complejo debido a la superposición de síntomas. El cintigrama de vaciamiento gástrico (CVG) y electrogas- trografía (EGG) tiene problemas de reproducibilidad. El Mapeo de superficie de Cuerpo Gástrico (MSCG) o conocida también como Alimetría gástrica, es una técnica avanzada que permite un mapeo electrofisiológico preciso y fiable, superando las limitaciones de la EGG. La Alimetría Gástrica mide los potenciales mioeléc - tricos gástricos, proporcionando datos útiles para el diagnóstico. El MGSC utiliza una matriz de electrodos para capturar la actividad gástrica y requiere un protocolo estandarizado para obtener datos comparables. Las métricas generadas ayudan a identificar fenotipos específicos de disfunción gástrica, mejorando la precisión diagnóstica. Estos avances prometen revolucionar el manejo clínico de los síntomas gástricos crónicos, ha - ciendo de esta revisión una lectura esencial para aquellos interesados en la investigación y tratamiento de problemas gastrointestinales


Assuntos
Humanos , Mapeamento Potencial de Superfície Corporal/métodos , Técnicas de Diagnóstico do Sistema Digestório , Motilidade Gastrointestinal/fisiologia
2.
Rev Gastroenterol Mex (Engl Ed) ; 84(2): 149-157, 2019.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-29903528

RESUMO

INTRODUCTION AND AIMS: Critically ill patients present with a broad spectrum of gastrointestinal motility disorders that affect the digestive tract. Our aim was to compare the effect of two prokinetic drugs on gastric electrical rhythm in critically ill septic patients, measured through surface electrogastrography (EGG). MATERIAL AND METHODS: A prospective triple-blinded randomized study was conducted on 36 patients admitted to the intensive care unit (ICU) with the diagnosis of septic shock. They were randomized to receive metoclopramide or domperidone. We assessed dominant frequency (DF), percentage distribution over time, and dominant power (DP), which represents the strength of contraction, before and after administration of the study drugs. RESULTS: Reliable electrogastrograms were achieved in all patients. In relation to the distribution of DF over time, 64% of patients had dysrhythmia, the mean baseline DF was 2.9 cpm, and the mean DP was 56.5µv After drug administration, 58% of the patients had dysrhythmia, the mean DF increased to 5.7 cpm (P<.05), and the DP did not change (57.4µv2). There were no significant differences between drugs. In the metoclopramide group, the baseline DF was 2.1 cpm and the baseline DP was 26.1µv2. The post-drug values increased to 5.4 cpm and 34.1µv2, respectively. In the domperidone group, the baseline DF was 3.7 cpm and the baseline DP was 86.9µv2. After drug administration, the DF increased to 6.1 cpm and the DP decreased to 83.5µv2. CONCLUSIONS: Both metoclopramide and domperidone similarly increased the DF of gastric pacemaker activity and improved gastric motility by restoring a normogastric pattern. Gastric dysmotility is frequent in septic patients.


Assuntos
Antieméticos/farmacologia , Estado Terminal , Domperidona/farmacologia , Endoscopia Gastrointestinal/métodos , Motilidade Gastrointestinal , Metoclopramida/farmacologia , Sepse/fisiopatologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Eletrodos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Projetos Piloto , Estudos Prospectivos
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