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Introduction: Nosocomial infectious ventriculitis caused by multidrug-resistant (MDR) Gram-negative bacilli associated with external ventricular drainage (EVD) placement poses a significant mortality burden and hospital costs. Objectives: This study aims to analyze the characteristics, ventriculitis evolution, treatment, and outcomes of patients with ventriculitis due to MDR Gram-negative bacilli associated with EVD placement. Methods: A retrospective cohort study focusing on patients with nosocomial infection caused by MDR Gram-negative bacilli while on EVD was conducted from 2019 to 2022. Medical, laboratory, and microbiological records were collected. The antibiotic resistance of the Gram-negative bacilli isolated in the cerebrospinal fluid (CSF) of patients was analyzed. The risk factors were identified using univariate risk models and were analyzed using survival curves (Cox regression). An adjusted Cox proportional hazards model was also constructed. Results: Among 530 patients with suspected EVD-associated ventriculitis, 64 patients with isolation of Gram-negative bacilli in CSF were included. The estimated mortality was 78.12%. Hemorrhages (intracranial, subarachnoid, and intraventricular) were observed in 69.8% of patients. Acinetobacter baumannii, Klebsiella pneumoniae, and Pseudomonas aeruginosa were the most frequently isolated bacilli. In the univariate analysis, significant risk factors for mortality included arterial hypertension, a Glasgow Coma Scale (GCS) score of ≤ 8, invasive mechanical ventilation (IMV) upon hospital admission and during hospitalization, septic shock, and ineffective treatment. The adjusted Cox proportional hazards model revealed that septic shock (HR = 3.3, 95% CI = 1.5-7.2; p = 0.003) and ineffective treatment (HR = 3.2, 1.6-6.5, 0.001) were significant predictors. A high resistance to carbapenems was found for A. baumannii (91.3%) and P. aeruginosa (80.0%). Low resistance to colistin was found for A. baumannii (4.8%) and P. aeruginosa (12.5%). Conclusion: Ineffective treatment was an independent hazard factor for death in patients with ventriculitis caused by MDR Gram-negative bacilli associated with EVD.
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STUDY DESIGN: Cross-sectional survey. OBJECTIVE: Although literature does not recommend routine wound drain utilization, there is a disconnect between the evidence and clinical practice. This study aims to explore into this controversy and analyze the surgeon preferences related to drain utilization, and the factors influencing drain use and criterion for removal. METHODS: A survey was distributed to AO Spine members worldwide. Surgeon demographics and factors related to peri-operative drain use in 1 or 2-level open fusion surgery for lumbar degenerative pathologies were collected. Multivariate analyses by drain utilization, and criterion of removal were conducted. RESULTS: 231 surgeons participated, including 220 males (95.2%), orthopedics (178, 77.1%), and academic/university-affiliated (114, 49.4%). Most surgeons preferred drain use (186, 80.5%) and subfascial drains (169, 73.2%). Drains were removed based on duration by 52.87% of the surgeons, but 27.7% removed drains based on outputs. On multivariable analysis, significant predictors of drain use were surgeon's aged 35-44 (OR = 11.9, 95% CI = 1.2-117.2, P = .034), 45-54 (29.1, 3.1-269.6, P = .003), 55-64 (8.9, 1.4-56.5, .019), and wound closure using coaptive films (6.0, 1.2-29.0, P = .025). Additionally, surgeons from Asia Pacific (OR = 5.19, 95% CI = 1.65-16.38, P = .005), Europe (3.55, 1.22-10.31, P = .020), and Latin America (4.40, 1.09-17.83, .038) were more likely to remove drain based on time duration, but surgeons <5 years of experience (10.23, 1.75-59.71, P = .010) were more likely to remove drains based on outputs. CONCLUSIONS: Most spine surgeons worldwide prefer to place a subfascial wound drain for degenerative open lumbar surgery. The choice for drain placement is associated with the surgeon's age and use of coaptive films for wound closure, while the criterion for drain removal is associated with the surgeons' region of practice and experience.
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BACKGROUND: The main treatments for hydrocephalus due to posterior fossa tumors are tumor resection with or without an external ventricular drain, ventriculoperitoneal shunt (VPS), and endoscopic third ventriculostomy. Although preoperative cerebrospinal fluid diversion by any of these techniques improves clinical outcomes, evidence comparing the efficacy of these techniques is scarce. Therefore, we aimed to retrospectively evaluate each treatment modality. METHODS: This single-center study analyzed 55 patients. Treatments were classified as successful (hydrocephalus resolution with a single surgical event) or failed and compared with a χ2 test. Kaplan-Meier curves and log-rank tests were employed. A Cox proportional hazard model was used to determine relevant covariates predicting outcomes. RESULTS: Mean patient age was 36.3 years, 43.4% of patients were men, and 50.9% of patients presented with uncompensated intracranial hypertension. Mean tumor volume was 33.4 cm3, and extent of resection was 90.85%. Tumor resection with or without an external ventricular drain was successful in 58.82% of cases, VPS was successful in 100%, and endoscopic third ventriculostomy was successful in 76.19% (P = 0.014). Mean follow-up time was 15.12 months. Log-rank test found statistically significant differences between survival curves of treatments (P = 0.016) favoring the VPS group. Postoperative surgical site hematoma was a significant covariate in the Cox model (hazard ratio = 17; 95% confidence ratio, 2.301-81.872; P = 0.004). CONCLUSIONS: This study favored VPS as the most reliable treatment of hydrocephalus due to posterior fossa tumors in adult patient; however, several factors influence clinical outcomes. We proposed an algorithm based on our findings and other authors' findings to facilitate the decision-making process.
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Neoplasias Encefálicas , Hidrocefalia , Neoplasias Infratentoriais , Terceiro Ventrículo , Masculino , Humanos , Adulto , Feminino , Estudos Retrospectivos , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/cirurgia , Neoplasias Encefálicas/cirurgia , Neoplasias Infratentoriais/complicações , Neoplasias Infratentoriais/diagnóstico por imagem , Neoplasias Infratentoriais/cirurgia , Hidrocefalia/etiologia , Hidrocefalia/cirurgia , Ventriculostomia/métodos , Derivação Ventriculoperitoneal/métodos , Terceiro Ventrículo/diagnóstico por imagem , Terceiro Ventrículo/cirurgia , Resultado do TratamentoRESUMO
PURPOSE: Drain placement in retromuscular ventral hernia repair is controversial. Although it may reduce seroma formation, there is a concern regarding an increase in infectious complications. We aimed to perform a meta-analysis on retromuscular drain placement in retromuscular ventral hernia repair. METHODS: We performed a literature search of Cochrane, Scopus and PubMed databases to identify studies comparing drain placement and the absence of drain in patients undergoing retromuscular ventral hernia repair. Postoperative outcomes were assessed by pooled analysis and meta-analysis. Statistical analysis was performed using RevMan 5.4. Heterogeneity was assessed with I2 statistics. RESULTS: 3808 studies were screened and 48 were thoroughly reviewed. Four studies comprising 1724 patients were included in the analysis. We found that drain placement was significantly associated with a decrease in seroma (OR 0.34; 95% CI 0.12-0.96; P = 0.04; I2 = 78%). Moreover, no differences were noted in surgical site infection, hematoma, surgical site occurrences or surgical site occurrences requiring procedural intervention. CONCLUSIONS: Based on the analysis of short-term outcomes, retromuscular drain placement after retromuscular ventral hernia repair significantly reduces seroma and does not increase infectious complications. Further prospective randomized studies are necessary to confirm our findings, evaluate the optimal duration of drain placement, and report longer-term outcomes.
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Hérnia Ventral , Hérnia Incisional , Humanos , Seroma/etiologia , Herniorrafia/efeitos adversos , Hérnia Ventral/cirurgia , Hérnia Ventral/complicações , Infecção da Ferida Cirúrgica/etiologia , Infecção da Ferida Cirúrgica/cirurgia , Drenagem , Telas Cirúrgicas/efeitos adversos , Hérnia Incisional/cirurgiaRESUMO
Many parts of the world receive from abroad not only objects of technology, but also scientific discoveries, and organizing elements and practices as well. Since these entities materially comprehend a formidable part of their modes of existence, let us say that non-Western countries result from ontologies/epistemologies that in large part come from abroad. This manifested coloniality emerges in the feeling of contradiction between national realities and the ideological prestige of the Western imperial centers that serve as models to them. This configures a malaise that is deeply rooted in educated Brazilians. I discuss lines of flight from that malaise in an articulation that configures a philosophical and political novelty in Brazil. In examples concerning computing in Brazil, I juxtapose elements of STS, the metaphorical anthropophagic movement, and the European Enlightenment project, to enact a more symmetrical, dialogical, and inclusive world by constructing 'respectful enough' stories. In doing so, the anthropophagic movement, previously in practice restricted to the artistic realms, incorporates sciences and technologies. In each of these stories, the enlightened motto 'daring to know' is juxtaposed with the anthropophagic metaphorical motto 'eat the stranger' around modern Western scientific and technological issues in local situated ways.
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Conhecimento , Tecnologia , Humanos , Brasil , EmoçõesRESUMO
In 2005, the Guatemala National Secretariat of Science and Technology (Senacyt) introduced Converciencia, a program designed to connect Guatemalan scientists residing abroad with their country of origin. Converciencia has been a flagship practice for over 15 years. This program involves three main groups of participants: (i) science and technology (S&T) policy agents, (ii) the scientific community (including parts of the Guatemala scientific diaspora, GSD), and (iii) host institutions (local co-organizers, mainly universities, and research institutes). This article presents a comprehensive and balanced overview of the Converciencia program applying an in-depth analysis of its creation, evolution, leading trends, and legacies. Using a qualitative methodology and conducting a four-level analysis (descriptive, explanatory, normative, and prescriptive) allowed for the identification of nuances of this S&T practice in the context of a scientifically lagging country such as Guatemala. The detailed data collected through documentary and desk review, gray literature, focus group discussions, and semi-structured interviews resulted in a framework to highlight the strengths, weaknesses, opportunities, and threats (SWOTs) in the planning, organization, implementation, monitoring, and perception of the results achieved by Converciencia. Findings portray the contrasting views and perceptions from a single S&T practice, depending on the participating parties' roles and responsibilities. Direct participants examined how Converciencia has achieved its objectives while questioning the effectiveness and impact that the resources allocated to the initiative have yielded over time. Evidence indicates that despite the design, coordination, and evaluation limits of Converciencia, the GSD, the scientific community in Guatemala, and the host institutions are interested in the continuity of the practice. Indeed, the main recommendation involves restructuring and turning Converciencia into a robust S&T policy. Converciencia as a policy engaging the GSD could produce greater results and impacts by involving all the key actors in co-designing activities, clearly determining roles and responsibilities, and establishing performance and impact indicators for evaluation.
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O cenário de violência urbana e a alta tecnologia automobilística culminaram no aumento de incidência de lesões penetrantes e contusas. Como o fígado ocupa a maior parte do quadrante superior do abdome, qualquer trauma na parte inferior do tórax ou no abdome superior o coloca em risco de lesão que pode acarretar vazamento biliar, sangue ou seroma. Portanto, a drenagem é indicada para evitar complicações causadas pelo acúmulo desses líquidos. Este estudo visou avaliar a efetividade da drenagem em procedimentos cirúrgicos de trauma hepático. Estudo observacional, com análise retrospectiva de prontuários onde foi avaliado um total de 60 prontuários. Em conclusão, os pacientes com lesões mais graves tiveram maior número de drenagem; o tempo de permanência em UTI foi semelhante àqueles que não utilizaram drenos; reoperações utilizaram o dreno com maior frequência; o uso ou não de drenagem não evidenciou diferenças quanto a necessidade de hemoderivados ou em relação ao número de óbitos
The urban violence scenario and the high automobile technology culminated in an increase in the incidence of penetrating and blunt injuries. Since the liver occupies most of the upper quadrant of the abdomen, any trauma to the lower chest or upper abdomen is risky for injury that can lead to bile leakage, blood, or seroma; therefore, drainage is indicated to avoid complications caused by the accumulation of these liquids. This study aimed to evaluate the effectiveness of drainage in surgical procedures for liver trauma. It is observational, with retrospective analysis of medical records. A total of 60 records were evaluated. In conclusion, patients with more severe injuries had a greater number of drainages; the length of stay in the ICU was similar to those who did not use drains; reoperations used the drain more frequently; the use or not of drainage did not show differences in terms of the need for blood products or in relation to the number of deaths
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Humanos , Traumatismos Torácicos , Ferimentos e Lesões , Drenagem , FígadoRESUMO
The underdevelopment of the higher education system in Guatemala and the fragility of its science and technology (S&T) contexts have compelled a significant number of talented Guatemalan scientists to be trained, educated, and employed abroad. The relocation of such skilled human power to different countries and regions has resulted in a growing Guatemalan Scientific Diaspora (GSD). Until recently, the emigration of scientists from the Global South to scientifically advanced countries in the North was studied as it negatively impacted the countries of origin. However, technological upgrades and globalization have progressively shifted the paradigm in which such scientific diasporas interact and connect, thus enabling them to influence their home countries positively. Due to the lack of knowledge-based evidence and functioning connecting platforms, the value and potential of the GSD in their involvement in proposing solutions to complex socio-economic, environmental, and other challenges faced by Guatemalan society remain unknown. Moreover, the lack of interaction of relevant stakeholders (S&T policy agents, international partners, higher education institutions and research centers, industry, and relevant not governmental organizations) represents a pervasive obstacle to the untapped impact of the GSD in the country. This study outlines the Guatemalan scientific diasporas' networking as a mechanism for building research excellence and intellectual capital. This force could respond to the need to strengthen the national science capacities and meet the demands for knowledge production and access to broader sectors of society. This research applied qualitative methodology that, through the conduction of focus group discussions and semi-structured interviews with members of the Guatemalan scientific community and relevant key stakeholders, delved into the existence and articulation of the GSD and potential stages for their engagement with their country of origin. Findings highlight the importance of digital and technological pathways that might leverage the GSD's knowledge and experience, channeling skills, and international connections for better interaction with the Guatemalan society. Furthermore, the discussion addresses how technology might turn brain drain into brain circulation, enabling the articulation of the GSD as a viable opportunity to generate collaboration between scientists abroad and local actors, ultimately impacting the building and development of Guatemalan science and national research capacities.
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Scientific diasporas from developing countries represent an opportunity to strengthen international collaborations. These collaborations build upon the desire of members of the diasporas to establish scientific, academic, technological, and cultural exchange networks with the communities in their country of origin. While Mexico has a significant number of scientists residing abroad, particularly in North America, and most of them are committed to aid in the country's development, institutional coordination has not harnessed its benefits. In this work, we present an analysis of initiatives carried out by Mexican scientists, members of the diaspora, studying or working in the United States of America and Canada. The study is based on a set of interviews with members of this diaspora. We asked scientists about the conditions that enabled or obstructed their initiatives back in Mexico, and we discussed the role of these factors for capacity building. We also provide general recommendations to enhance contributions to the advancement of science in the country.
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Background: Pulmonary bullae are thin-walled cavitary lesions within the subpleural parenchyma. They are a result of thedestruction, dilatation and coalescence of bordering alveoli and their rupture is the most common cause of pneumothoraxin dogs. Radiographic and CT imaging are excellent tools for identifying and quantifying pneumothorax. Surgical treatment is considered standard for treatment of pneumothorax consequential to pulmonary bullae. The aim of this report wasto describe a case of pneumothorax secondary to pulmonary bullae in a dog.Case: A 5-year-old male crossbreed dog, weighing 11.5 kg, was presented to the Uberabas Veterinary Hospital due to becoming easily tired in the previous 3 weeks, and its worsening in the last 2 days by presenting panting. The dogs guardiandid not witness any traumas, but informed that the animal resided with other 14 dogs and also that it frequently collidedthe thorax against the door when it came down from the bed. Physical examination showed diaphragmatic breathing,inspiratory dyspnea and stridor lung sound. Thoracocentesis revealed presence of air in the pleural cavity and pneumothorax. Radiographic images confirmed this condition. The dog stayed in the hospital and chest drains were placed. Sincethe amount of sucked air did not reduce with time and due to the emergence of subcutaneous emphysema, the dog wentthrough exploratory thoracotomy that revealed impairment of the right caudal lung lobe, proceeding to lobectomy. Thedog stayed in the hospital with chest drains until the contents of the suctions reduced significantly. With the removal ofthe drains, the dog was sent home and had a full recovery. Histopathology of the impaired lung revealed pulmonary bullae.Discussion: The dog from this report presented clinical signs consistent with pneumothorax, such as dyspnea, diaphragmaticbreathing and exercise intolerance. Radiography of the chest region revealed...
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Masculino , Animais , Cães , Dispneia/veterinária , Drenagem Postural/veterinária , Pneumotórax/cirurgia , Pneumotórax/veterinária , Pneumonectomia/veterinária , Toracotomia/tendênciasRESUMO
BACKGROUND: Spontaneous intracranial hypotension (SIH) is an uncommon, benign, and generally self-limiting condition caused by low cerebrospinal fluid (CSF) volume and pressure usually caused by a CSF leak. Patients with SIH have an increased incidence of subdural hematomas (SDH), which may be bilateral and recurrent. CASE DESCRIPTION: We report a unique case of a man presenting with SIH and bilateral SDH that were drained with bilateral craniotomies. During drain removal, the patient had an acute neurological deterioration and a CT scan showed SDH recurrence. The patient had two new recurrent SDH afterwards. After the third surgical intervention, the drain was removed in the OR with concomitant subdural saline infusion, there was no recurrence of SDH after that and the patient has had no further complications after a 2-year follow-up. CONCLUSION: Patients with intracranial hypotension are predisposed to form SDH. In this case, drain removal caused further decrease in intracranial pressure and triggered a new SDH formation, subdural saline irrigation masked atmospheric pressure and prevented this complication from happening again.
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Abstract Introduction: Percutaneous drains can be associated with several complications, including infection, fistula formation, discomfort and prolonged hospitalization. Objective: The aim of this study was to evaluate the safety of submandibular gland excision without the use of surgical drains. Methods: We analyzed the surgery time, postoperative complications such as bleeding, facial palsy, seroma, and repeat exploration of wounds and duration of the hospital stay. Excision of the submandibular gland via a transcervical approach was undertaken by two surgeons. Prior to wound closure, the skin flap and wound bed were approximated using hemostatic fibrin glue (Greenplast-Q PFS KIT®, GC Greencross, Youngin, Korea). Neither saline irrigation nor insertion of a percutaneous drain were included. Results: A total of 23 patients underwent submandibular gland excision. The study group consisted of 14 men (60.8%) and 9 women (39.2%) (mean age, 47.6 years; range, 24-70 years). There were two patients who had minor complications. One patient showed minor bleeding on the skin incision line immediately postoperatively, and one developed a seroma at 7 days postoperatively. There were no major surgical complications. Total duration of the surgery from skin incision to closure averaged 44.86 minutes. Mean duration of the hospital stay was 3.17 days. Patients were discharged on average at 1.17 days after surgery. Conclusion: The submandibular gland can be safely excised without the use of a surgical drain, therefore allowing early patient discharge.
Resumo Introdução: Os drenos percutâneos apresentam várias complicações associadas, inclusive infecção, formação de fístulas, desconforto e permanência hospitalar prolongada. Objetivo: Avaliar a segurança da excisão da glândula submandibular sem o uso de drenos cirúrgicos. Método: Analisamos o tempo de cirurgia, as complicações pós-operatórias tais como sangramento, paralisia facial, seroma e necessidade de reexploração de ferida operatória, e a duração da internação hospitalar. A excisão da glândula submandibular por via transcervical foi realizada por dois cirurgiões. Antes do fechamento da incisão, o retalho cutâneo e o leito da ferida operatória foram aproximados utilizando cola hemostática de fibrina (Greenplast-Q PFS KIT®, GC Greencross, Youngin, República da Coréia). Não houve irrigação salina nem uso de dreno percutâneo. Resultados: Foram submetidos 23 pacientes à excisão da glândula submandibular. O grupo de estudo consistiu em 14 homens (60,8%) e 9 mulheres (39,2%) (média de 47,6 anos; variação de 24 a 70). Dois pacientes apresentaram complicações menores. Um paciente apresentou pequeno sangramento na incisão da pele no pós-operatório imediato e um deles teve seroma aos 7 dias de pós-operatório. Não houve complicações cirúrgicas importantes. A duração total da cirurgia, desde a incisão na pele até o fechamento, foi de 44,86 minutos. A duração média da internação hospitalar foi de 3,17 dias. Os pacientes receberam alta em média 1,17 dia após a cirurgia. Conclusão: A glândula submandibular pode ser excisada com segurança sem o uso de dreno cirúrgico, permitindo que o paciente tenha alta hospitalar mais precocemente.
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Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Idoso , Adulto Jovem , Glândula Submandibular , Doenças da Glândula Submandibular , Complicações Pós-Operatórias , Retalhos Cirúrgicos , Tempo de InternaçãoRESUMO
Background: Laparoscopic Roux-en-Y gastric bypass (RYGB) is one of the most common procedures to treat morbid obesity. Abdominal drains are often placed during the operation to detect complications earlier. The aim of this study was to assess the benefit of routine drain placement during laparoscopic RYGB. Materials and Methods: A consecutive series of patients undergoing laparoscopic RYGB between 2017 and 2018 was analyzed. The sample was randomized before the procedure into two groups: with abdominal drain (G1) and without abdominal drain placement (G2). Patients with intraoperative complications were excluded from the randomization. Postoperative complications and pain (visual analogue scale) were compared between groups. Results: A total of 84 patients were included; 45 belonged to G1 and 39 to G2. Mean age (G1 44 years versus G2 48 years) and body mass index (G1 43 kg/m2 versus G2 44 kg/m2) were similar in both groups. There were no significant differences between groups in preoperative comorbidities. Mean operative time was 92 minutes in both groups. Mean pain score at postoperative day 0 was similar in both groups (G1 3.2 versus G2 3.5, P = .58), but was higher in G1 at postoperative day 1 (G1 3.1, G2 1.1, P = .02). Postoperative Clavien-Dindo I-II complications were similar in both groups (G1 9% versus G2 1%, P = .37). No major complications, reoperations, or 30-day mortality occurred in the entire cohort. Conclusions: Drain placement in laparoscopic RYGB was associated with greater postoperative pain and did not show benefits in early detection of postoperative complications. Routine placement of abdominal drain in laparoscopic RYGB might not be recommended.
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Drenagem , Derivação Gástrica/métodos , Abdome , Adulto , Idoso , Anastomose em-Y de Roux/efeitos adversos , Anastomose em-Y de Roux/métodos , Índice de Massa Corporal , Drenagem/efeitos adversos , Feminino , Derivação Gástrica/efeitos adversos , Humanos , Intestino Delgado/cirurgia , Laparoscopia/efeitos adversos , Laparoscopia/métodos , Masculino , Pessoa de Meia-Idade , Obesidade Mórbida/cirurgia , Duração da Cirurgia , Dor Pós-Operatória/etiologia , Período Pós-Operatório , Estômago/cirurgia , Adulto JovemRESUMO
INTRODUCTION: Percutaneous drains can be associated with several complications, including infection, fistula formation, discomfort and prolonged hospitalization. OBJECTIVE: The aim of this study was to evaluate the safety of submandibular gland excision without the use of surgical drains. METHODS: We analyzed the surgery time, postoperative complications such as bleeding, facial palsy, seroma, and repeat exploration of wounds and duration of the hospital stay. Excision of the submandibular gland via a transcervical approach was undertaken by two surgeons. Prior to wound closure, the skin flap and wound bed were approximated using hemostatic fibrin glue (Greenplast-Q PFS KIT®, GC Greencross, Youngin, Korea). Neither saline irrigation nor insertion of a percutaneous drain were included. RESULTS: A total of 23 patients underwent submandibular gland excision. The study group consisted of 14 men (60.8%) and 9 women (39.2%) (mean age, 47.6 years; range, 24-70 years). There were two patients who had minor complications. One patient showed minor bleeding on the skin incision line immediately postoperatively, and one developed a seroma at 7 days postoperatively. There were no major surgical complications. Total duration of the surgery from skin incision to closure averaged 44.86minutes. Mean duration of the hospital stay was 3.17 days. Patients were discharged on average at 1.17 days after surgery. CONCLUSION: The submandibular gland can be safely excised without the use of a surgical drain, therefore allowing early patient discharge.
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Doenças da Glândula Submandibular , Glândula Submandibular , Adulto , Idoso , Feminino , Humanos , Tempo de Internação , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias , Retalhos Cirúrgicos , Adulto JovemRESUMO
QUESTIONS: In patients with a collection of fluid in the pleural space, do mobilisation and respiratory techniques: shorten the drainage period and length of hospital stay; improve respiratory function and oxygenation; and prevent pulmonary complications? Does the addition of positive airway pressure to this regimen further improve the effects? DESIGN: Randomised controlled trial with three intervention arms, concealed allocation, intention-to-treat analysis and blinded assessment. PARTICIPANTS: One hundred and fifty-six inpatients with a fluid collection in the pleural space and with chest drainage in situ. INTERVENTION: Participants received usual care and were randomly assigned to: a control group that also received sham positive airway pressure (4 cmH2O) only (Con); an experimental group that received incentive spirometry, airway clearance, mobilisation and the same sham positive pressure (Exp1); or an experimental group that received the Exp1 regimen except that the positive airway pressure was 15 cmH2O (Exp2). Treatments were provided three times per day for 7 days. OUTCOME MEASURES: Days of chest tube drainage, length of hospital stay, pulmonary complications and adverse events were recorded until hospital discharge. Costs in each group were estimated. RESULTS: The Exp2 group had shorter duration of chest tube drainage and length of hospital stay compared with the Exp1 and Con groups. In addition, the Exp2 group had less antibiotic use (18% versus 43% versus 55%) and pneumonia incidence (0% versus 16% versus 20%) compared with the Exp1 and Con groups (all p < 0.01). The groups had similar rates of adverse events (10% versus 2% versus 6%, p > 0.05). Total treatment costs were lower in the Exp2 group than in the Exp1 and Con groups. CONCLUSIONS: In patients with a fluid collection in the pleural space, the addition of positive pressure to mobilisation and respiratory techniques decreased the duration of thoracic drainage, length of hospital stay, pulmonary complications, antibiotic use and treatment costs. REGISTRATION: ClinicalTrials.govNCT02246946.
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Exercícios Respiratórios/métodos , Pressão Positiva Contínua nas Vias Aéreas/métodos , Drenagem/métodos , Modalidades de Fisioterapia , Derrame Pleural/terapia , Adulto , Terapia Combinada , Feminino , Humanos , Tempo de Internação , Masculino , EspirometriaRESUMO
Introdução: A abdominoplastia é um procedimento para a melhoria do contorno corporal e a técnica tem sido aprimorada pela associação da dissecção limitada do retalho cutâneo e pontos de adesão no mesmo ato operatório, evitando-se a formação de seroma pós-abdominoplastia, complicação que incomoda tanto o paciente quanto o cirurgião. Portanto, o objetivo é avaliar se o uso de pontos de adesão está associado a menor incidência de seroma após abdominoplastia quando comparado ao uso de drenos. Métodos: Revisão sistemática da literatura com metanálise, envolvendo as seguintes bases de dados: Science Direct, Scielo, Pubmed, Lilacs, CINAHL e Scopus. Para analisar os dados foi utilizado o programa Stata 12.0 e a estatística I² proposta por Higgins, com intervalo de confiança de 95% para o risco relativo para seroma, segundo o tipo de intervenção (dreno, ponto de adesão, dreno com ponto de adesão). Sendo registrado no PROSPERO sob o número CRD42019120399. Resultados: Cinco estudos preencheram os critérios de inclusão e foram incluídos na metanálise. Ao comparar o uso de dreno de sucção com pontos de adesão, os pontos de adesão mostraram um fator de proteção na prevenção do seroma (RR: 0,13; IC 95%: 0,02-0,66). Conclusão: Os achados sugerem que o uso de pontos de adesão em abdominoplastia em detrimento do uso de drenos pode ser uma técnica eficaz para prevenção da formação de seromas.
Introduction: Abdominoplasty, which aims to improve body contour, has been upgraded by its association with limited dissection of the cutaneous flap and quilting sutures in the same surgery to avoid the formation of postabdominoplasty seroma, a complication that troubles both patient and surgeon. Therefore, this study aimed to assess whether the use of quilting sutures is associated with a lower incidence of seroma after abdominoplasty than the use of drains. Methods: A systematic review of the literature and a meta-analysis were performed of the Science Direct, Scielo, Pubmed, Lilacs, CINAHL, and Scopus databases. The data analysis was performed using the Stata 12.0 program and the I² statistic proposed by Higgins, with a 95% confidence interval for the relative risk for seroma by intervention type (drain, quilting sutures, drain with quilting sutures). The study was registered in PROSPERO (CRD42019120399). Results: Five studies met the inclusion criteria and were included in the meta-analysis. Quilting sutures showed a protective effect (versus use of drain with quilting sutures) in the prevention of seroma (relative risk, 0.13; 95% confidence interval, 0.020.66). Conclusion: These findings suggest that the use of quilting sutures instead of drains in abdominoplasty can effectively prevent seroma formation.
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Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , História do Século XXI , Sucção , Cirurgia Plástica , Drenagem , Metanálise como Assunto , Seroma , Abdome , Abdominoplastia , Sucção/métodos , Sucção/estatística & dados numéricos , Cirurgia Plástica/métodos , Cirurgia Plástica/estatística & dados numéricos , Drenagem/métodos , Drenagem/estatística & dados numéricos , Seroma/cirurgia , Seroma/terapia , Abdominoplastia/métodos , Abdominoplastia/estatística & dados numéricos , Abdome/cirurgiaRESUMO
Introducción: Se hizo una revisión de las historias clínicas de los pacientes con síndrome de Mirizzi tratados en el Hospital de Clínicas durante el período de enero de 2006 a diciembre de 2015, y se describe su presentación y la importancia de la complejidad en su manejo. Objetivo: Determinar la prevalencia de síndrome de Mirizzi en pacientes operados por patología biliar y manejo del mismo en la II Cátedra de Clínica Quirúrgica del Hospital de Clínicas de San Lorenzo.Pacientes y método:Estudio observacional, descriptivo, retrospectivo de corte trasverso. Se describe edad, sexo, diagnóstico de colelitiasis, cuadro clínico, exámenes complementarios, manejo quirúrgico, estancia hospitalaria, morbilidad y mortalidad. Resultados:Se diagnosticaron 21 pacientes. Siendo los más prevalentes el tipo I y II. Una media de 52 años. Todos presentaron dolor abdominal, ictericia (52%). Ningún paciente fue diagnosticado antes de la cirugía. En el Tipo l, se realizaron 8 colecistectomías con distintos abordajes. Tipo II, finalizaron en su totalidad por vía convencional. Las demás clasificaciones tuvieron un tratamiento quirúrgico específico.Conclusión: El síndrome de Mirizzi es una patología compleja de difícil diagnostico pre quirúrgico. La ecografía no es específica para esta patología. Todos los casos se detectaron en el intraoperatorio.
Introduction: A review of the medical records of patients with Mirizzi syndrome treated at the Hospital de Clínicas during the period from January 2006 to December 2015 was made, describing their presentation and the importance of the complexity in their management. Objective: To determine the prevalence of Mirizzi syndrome in patients operated by biliary pathology and show their management in the II Cátedra de Clínica Quirúrgica del Hospital de Clínicas de San Lorenzo. Patients and method: Observational, descriptive, retrospective cross-sectional study. Age, sex, diagnosis of cholelithiasis, clinical picture, complementary examinations, surgical management, hospital stay, morbidity and mortality are described. Results: Twenty-one patients were diagnosed. The most prevalent being types I and II. An average of 52 years. All had abdominal pain, jaundice (52%). No patient was diagnosed prior to surgery. In Type I, eight cholecystectomies were performed with different approaches. Type II, were terminated in their entirety by conventional route. The other classifications had a specific surgical treatment. Conclusion: Mirizzi syndrome is a complex pathology that is difficult to diagnose preoperatively. Ultrasound is not specific for this pathology. All cases were detected intraoperatively.
Assuntos
Ducto Colédoco , Ultrassonografia , DrenagemRESUMO
BACKGROUND: Aedes aegypti, the principal vector for dengue, chikungunya and Zika viruses, is a synanthropic species that uses stagnant water to complete its reproductive cycle. In urban settings, rainfall water draining structures, such as storm drains, may retain water and serve as a larval development site for Aedes spp. reproduction. Herein, we describe the effect of a community-based intervention on preventing standing water accumulation in storm drains and their consequent infestation by adult and immature Ae. aegypti and other mosquitoes. METHODS: Between April and May of 2016, local residents association of Salvador, Brazil, after being informed of water accumulation and Ae. aegypti infestation in the storm drains in their area, performed an intervention on 52 storm drains. The intervention consisted of placing concrete at the bottom of the storm drains to elevate their base to the level of the outflow tube, avoiding water accumulation, and placement of a metal mesh covering the outflow tube to avoid its clogging with debris. To determine the impact of the intervention, we compared the frequency at which the 52 storm drains contained water, as well as adult and immature mosquitoes using data from two surveys performed before and two surveys performed after the intervention. RESULTS: During the pre-intervention period, water accumulated in 48 (92.3%) of the storm drains, and immature Ae. aegypti were found in 11 (21.2%) and adults in 10 (19.2%). After the intervention, water accumulated in 5 (9.6%) of the storm drains (P < 0.001), none (0.0%) had immatures (P < 0.001), and 3 (5.8%) contained adults (P = 0.039). The total number of Ae. aegypti immatures collected decreased from 109 to 0 (P < 0.001) and adults decreased from 37 to 8 (P = 0.011) after the intervention. Collection of immature and adult non-Aedes mosquitoes (mainly Culex spp.) in the storm drains also decreased after the intervention. CONCLUSION: This study exemplifies how a simple intervention targeting storm drains can result in a major reduction of water retention, and, consequently, impact Ae. aegypti larval populations. Larger and multi-center evaluations are needed to confirm the potential of citywide structural modifications of storm drains to reduce Aedes spp. infestation level.
Assuntos
Aedes/fisiologia , Febre de Chikungunya/prevenção & controle , Vírus da Dengue/fisiologia , Dengue/prevenção & controle , Insetos Vetores/fisiologia , Aedes/virologia , Animais , Brasil , Febre de Chikungunya/virologia , Culex/fisiologia , Culex/virologia , Dengue/virologia , Drenagem Sanitária , Entomologia , Insetos Vetores/virologia , Larva , Controle de Mosquitos , ReproduçãoRESUMO
We assessed healthcare provider perspectives of international aid four years after the Haiti Earthquake to better understand the impact of aid on the Haitian healthcare system and learn best practices for recovery in future disaster contexts. We conducted 22 semi-structured interviews with the directors of local, collaborative, and aid-funded healthcare facilities in Leogane, Haiti. We coded and analysed the interviews using an iterative method based on a grounded theory approach of data analysis. Healthcare providers identified positive aspects of aid, including acute emergency relief, long-term improved healthcare access, and increased ease of referrals for low-income patients. However, they also identified negative impacts of international aid, including episodes of poor quality care, internal brain drain, competition across facilities, decrease in patient flow to local facilities, and emigration of Haitian doctors to abroad. As Haiti continues to recover, it is imperative for aid institutions and local healthcare facilities to develop a more collaborative relationship to transition acute relief to sustainable capacity building. In future disaster contexts, aid institutions should specifically utilise quality of care metrics, NGO Codes of Conduct, Master Health Facility Lists, and sliding scale payment systems to improve disaster response.