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1.
Br J Nutr ; 130(10): 1779-1786, 2023 11 28.
Artigo em Inglês | MEDLINE | ID: mdl-36938805

RESUMO

The final stage of Fe deficiency is Fe deficiency anaemia, with repercussions for human health, especially in children under 5 years of age. Studies conducted in Brazilian public daycare centres show high prevalence of anaemia. The present study aims to evaluate the availability of Fe in the meals of the Municipal Centers of Early Childhood Education in Maceió. The experimental design comprises selection of algorithms, menu evaluation, calculation of the estimates, comparison between the estimates obtained and the recommendations, and analysis of correlation between meal constituents, and of the concordance between the absorbable Fe estimates. Four algorithms were selected and a monthly menu consisting of 22 d. The correlation analysis showed a moderate positive correlation to animal tissue (AT) v. non-heme iron (r = 0·42; P = 0·04), and negative to AT v. Ca (r = -0·54; P = 0·09) and Ca v. phytates (r = -0·46, P = 0·03). Estimates of absorbable Fe ranged from 0·23 to 0·44 mg/d. The amount of Fe available, unlike the total amount of Fe offered, does not meet the nutritional recommendations on most school days. The Bland-Altman analysis indicated that the Monsen and Balinfty and Rickard et al. showed greater agreement. The results confirm the need to adopt strategies to increase the availability of Fe in school meals.


Assuntos
Anemia Ferropriva , Ferro , Criança , Animais , Humanos , Pré-Escolar , Brasil/epidemiologia , Anemia Ferropriva/epidemiologia , Refeições
2.
Nutrients ; 14(11)2022 May 31.
Artigo em Inglês | MEDLINE | ID: mdl-35684114

RESUMO

Analyzing pregnant women's iron intake using dietary patterns would provide information that considers dietary relationships with other nutrients and their sources. The objective of this study was to evaluate the reproducibility and relative validity of a Qualitative Food Frequency Questionnaire to identify iron-related dietary patterns (FeP-FFQ) among Mexican pregnant women. A convenience sample of pregnant women (n = 110) completed two FeP-FFQ (FeP-FFQ1 and FeP-FFQ2) and a 3-day diet record (3DDR). Foods appearing in the 3DDR were classified into the same food groupings as the FeP-FFQ, and most consumed foods were identified. Exploratory factor analysis was used to determine dietary patterns. Scores were compared (FeP-FFQ for reproducibility and FeP-FFQ1 vs. 3DDR for validity) through intraclass correlation coefficients (ICC), cross-classification, Bland−Altman analysis, and weighed Cohen kappa (κw), using dietary patterns scores tertiles. Two dietary patterns were identified: "healthy" and "processed foods and dairy". ICCs (p < 0.01) for "healthy" pattern and "processed foods and dairy" pattern were 0.76 for and 0.71 for reproducibility, and 0.36 and 0.37 for validity, respectively. Cross-classification and Bland−Altman analysis showed good agreement for reproducibility and validity; κw values showed moderate agreement for reproducibility and low agreement for validity. In conclusion, the FeP-FFQ showed good indicators of reproducibility and validity to identify dietary patterns related to iron intake among pregnant women.


Assuntos
Ferro , Gestantes , Dieta , Registros de Dieta , Inquéritos sobre Dietas , Fast Foods , Feminino , Humanos , Gravidez , Reprodutibilidade dos Testes , Projetos de Pesquisa , Inquéritos e Questionários
3.
Rev. chil. nutr ; 48(1)feb. 2021.
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1388469

RESUMO

RESUMEN Propósito: Relacionar la ingesta dietaria de hierro con el estado nutricional de éste en una muestra de mujeres en edad fértil de Santiago de Chile. Método: A 51 mujeres entre 18 - 35 años se aplicó una Encuesta de Tendencia de Consumo para estimar el aporte de hierro dietario, junto con la medición de los biomarcadores bioquímicos a modo de determinar el estado de los depósitos de hierro. Mediante prueba estadística de Mann-Whitney se analizaron diferencias significativas entre los grupos según estado nutricional del hierro y sus parámetros sanguíneos. Resultados: Treinta y siete de las participantes (72,5%) no cumple con la ingesta recomendada de hierro diario. Dos de las mujeres presentaron anemia, 2 deficiencia de hierro sin anemia y 12 tenía los depósitos de hierro depletados. Tres de las mujeres que presentaron depósitos deficientes tuvieron una ingesta de hierro adecuada, mientras que el 71% de las mujeres con depósitos normales presentaron una ingesta de hierro insuficiente. Conclusiones: Hay un bajo cumplimiento de los requerimientos diarios de hierro y no se observan mejores valores hematológicos a mayor ingesta de hierro, a pesar de presentar un alto porcentaje con depósitos normales de hierro. Se requiere mayor análisis de la alimentación de este grupo de la población para identificar el tipo de hierro que se está aportando principalmente y si hay otros factores dietarios y no dietarios afectando los depósitos de hierro.


ABSTRACT Objectives: To relate dietary intake of iron with iron status in a sample of women of childbearing age from Santiago de Chile. Methods: A Food Frequency Survey was applied to 51 women between 18 - 35 years of age to estimate intake of dietary iron, together with the measurement of biochemical biomarkers to determine iron stores. Using the Mann-Whitney statistical test, significant differences were analyzed between the groups according to nutritional status of iron and its blood parameters. Results: Thirty seven of the participants (72.5%) do not meet the recommended daily iron intake. Two had anemia, 2 had iron deficiency without anemia, and twelve had depleted iron stores. Three women with deficient iron stores had an adequate iron intake, while 71% of women with normal iron stores showed an insufficient iron intake. Conclusions: We observed a low compliance with the daily iron requirements and no better hematological values were associated with higher iron intake, despite a high percentage of women with normal iron stores. To identify the type of iron mainly contributed by the diet and if there are other dietary and non-dietary factors affecting iron stores, further analysis of this population group is required.

4.
Rev. chil. nutr ; 47(5): 782-791, set. 2020. tab, graf
Artigo em Espanhol | LILACS | ID: biblio-1138615

RESUMO

RESUMEN Una dieta vegetariana se define por la exclusión total o parcial de alimentos de origen animal. Cuando es planificada adecuadamente puede prevenir y tratar enfermedades. Sin embargo, una dieta restrictiva en ciertos alimentos debe ser evaluada. El propósito de esta investigación fue describir parámetros antropométricos, hábitos de alimentación y de estilo de vida en ovo-lácteo-vegetarianos y veganos y explorar diferencias en la ingesta de nutrientes críticos entre ambos grupos. Estudio descriptivo de corte transversal, realizado en ovo-lácteo-vegetarianos y veganos de Asunción, Paraguay, durante el 2015. Se evaluaron parámetros antropométricos,, ingesta y hábitos de estilo de vida saludable. Participaron 17 ovo-lácteo-vegetarianos y 14 veganos. El 67,7 % (n= 21) se encontró normopeso, el 29 % (n= 9) presentó exceso de peso, y el 3,2% (n=1) bajo peso. Se presentó una ingesta inferior a los requerimientos en energía, carbohidratos, proteínas y grasas en ambos grupos de vegetarianos, e ingesta muy limitada de calcio y vitamina B12 en veganos. Las mujeres presentaron ingesta muy por debajo de las recomendaciones para hierro y calcio. Ninguna mujer vegana cumplió con la recomendación dietaria de vitamina B12. Al comparar grupos, se hallaron diferencias significativas en proteínas, calcio (menor consumo en veganos) y fibra (menor en ovo-lácteo-vegetarianos). La suplementación con vitaminas y suplementos también fue muy baja. Los resultados resaltan la importancia de una evaluación constante de la ingesta de nutrientes en una dieta vegetariana, a modo de evitar deficiencias o excesos, y la insoslayable tarea del nutricionista para el asesoramiento alimentario-nutricional a los individuos que expresen interés en adoptar este tipo de dieta.


ABSTRACT A vegetarian diet is defined by the total or partial exclusion of foods of animal origin. When properly planned it can prevent and treat disease. However, a restrictive diet in certain foods must be evaluated. The purpose of this research was to describe anthropometric parameters, eating and lifestyle habits of lacto-ovo-vegetarians and vegans, and to explore differences in critical nutrient intake between both groups. We conducted a descriptive cross-sectional study, carried out among lacto-ovo-vegetarians and vegans in the city of Asunción, Paraguay, during 2015. Anthropometric parameters,, intake and healthy lifestyle habits were evaluated. Seventeen lacto-ovo-vegetarians and 14 vegans participated. 67.7% (n= 21) were normal weight, 29.1% (n= 9) were overweight, and 3.2% (n= 1) were underweight. There was an intake lower than the requirements in terms of energy, carbohydrates, proteins and fats in both groups of vegetarians, and very limited intake of calcium and vitamin B12 in vegans. Women particularly had intake well below the recommendations for iron and calcium. No woman on a vegan diet met the dietary recommendation for vitamin B12. When comparing groups, significant differences were found in terms of protein and calcium, (lower consumption in vegans), fiber (lower in lacto-ovo-vegetarians). Vitamin supplementation was also very low. The results highlight the importance of constant evaluation of nutrient intake in a vegetarian diet in order to avoid deficiencies or excesses, and the very important work of the nutritionist for food and nutritional advice for individuals who express interest in adopting this type of diet.


Assuntos
Humanos , Masculino , Feminino , Dieta Vegetariana , Nutrientes , Estado Nutricional , Carboidratos , Proteínas , Estilo de Vida
5.
Rev. cuba. hematol. inmunol. hemoter ; 30(3): 233-242, jul.-set. 2014.
Artigo em Espanhol | LILACS | ID: lil-723761

RESUMO

Introducción: en donantes de sangre es importante conocer el hierro circulante, almacenado y funcional; tradicionalmente solo se incluye la medición de hemoglobina. Objetivo: describir el comportamiento del estado del hierro en donantes habituales según las características demográficas e ingesta de hierro y su relación con la ferritina, la hemoglobina y la hemoglobina reticulocitaria. Métodos: estudio descriptivo transversal que incluyó 70 donantes habituales del Banco de Sangre de la Universidad de Antioquia, seleccionados al azar. Se evaluaron la ferritina, el eritrograma, la hemoglobina reticulocitaria, el estudio coprológico, la actividad física y el consumo de hierro. Se calcularon medidas de resumen, frecuencias y se utilizaron las siguientes pruebas estadísticas t Student, U de Mann Withney, H de Kruskal Wallis, Anova y correlaciones, con un nivel de significación de p<0.05. Resultados: el 60 % de los donantes fueron mujeres y la edad promedio fue 33 años. El promedio de los parámetros eritrocitarios evaluados estuvo dentro de los valores de referencia; 14,3 % (n=10) presentaron ferropenia y 76,9 % (n=50) bajo consumo de hierro/día. Los hombres evidenciaron valores más altos para recuento de eritrocitos, hemoglobina, hematocrito, constantes corpusculares y ferritina. Los adolescentes (18-20 años) tuvieron valores más bajos de ingesta, reticulocitos y ancho de distribución eritrocitaria. La ferritina se correlacionó con la hemoglobina, hemoglobina corpuscular media, concentración de hemoglobina corpuscular media, ancho de distribución eritrocitaria y hemoglobina reticulocitaria. Conclusiones : se evidenciaron adecuados mecanismos reguladores del metabolismo del hierro con eritropoyesis eficiente y se sugieren estudios para evaluar aspectos nutricionales en los donantes y factibilidad de la determinación de ferritina en donantes habituales para verificar reservas adecuadas que compensen las pérdidas de sangre por la donación.


Introduction: in blood donors it is important to determine circulated, stored and functional iron; traditionally hemoglobin is the unique measurement included. Objective: we intended to describe the behavior of iron in repetitive donors according to demographic characteristics as well as iron intake, and its relation to ferritin, hemoglobin and reticulocyte hemoglobin. Methods: cross-sectional study of 70 repetitive donors at the University of Antioquía Blood Bank, selected at random. Ferritin, eritrogram, reticulocyte hemoglobin, stool, physical activity and iron dietary were evaluated. Summary measures and frequencies were calculated and the following tests were used: T Student, U of Mann Whitney, H of Kruskal Wallis, Anova and correlations in SPSS. Results: 60% of donors were women and the mean age was 33 years old. The median of the erythrocyte parameters evaluated was within reference values; 14,3 % (n = 10) showed iron deficiency and 76,9 % (n = 50) had low iron intake/day. Men got higher values for erythrocyte count, hemoglobin, hematocrit, corpuscular constants and ferritin. Teenagers (18 - 20 years old) had lower values in intake, reticulocytes and red blood cell distribution width. Ferritin correlated to hemoglobin, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, red blood cell distribution width and reticulocyte hemoglobin. Conclusion: adequate regulatory mechanisms of iron metabolism with efficient erythropoiesis were evident and we suggest further studies to evaluate nutritional aspects of the blood donors and the feasibility of ferritin determination in regular donors in order to verify adequate reserves to compensate blood caused by donation.

6.
Rev. cienc. salud (Bogotá) ; 12(2): 213-228, ago. 2014. graf, tab
Artigo em Espanhol | LILACS, COLNAL | ID: lil-715279

RESUMO

Objetivos: Analizar el consumo de hierro en adultos sanos de Medellín según aspectos demográficos y su correlación con la hemoglobina. Materiales y métodos: Estudio transversal correlativo en 109 sujetos. Se aplicó una encuesta semicuantitativa de frecuencia de consumo de alimentos fuente de hierro teniendo en cuenta la frecuencia del consumo y la porción. Se calcularon medidas de resumen y frecuencias, U de Mann Withney, H de Kruskal Wallis, Anova y correlación de Spearman, empleando SPSS versión 20.0 y se consideró un nivel de significación estadística de 0,05. Resultados: La edad promedio fue 32 años, 64,2% eran del sexo femenino, 81,6% con estudios técnicos o universitarios, 29,3% estudiantes y 43,9% de estrato social bajo. Se halló un consumo diario de 12,3 mg/día en promedio, 61% proveniente de hierro no hem. El hierro total consumido fue estadísticamente más alto en desempleados que en trabajadores, estudiantes y amas de casa. Al igual que el consumo de hierro hem en individuos con posgrado. No se observaron diferencias significativas al comparar el consumo de hierro por sexo, estrato, grupo etario y cuantificación de hemoglobina. Conclusiones: La baja ingesta del hierro no se ve influenciada por el sexo ni por el grupo etario, pero sí por ocupación y escolaridad, y es un factor que no permite disminuir las prevalencias de deficiencia de hierro y otros micronutrientes. Se requiere implementar más y mejores estrategias de educación nutricional y de aumento de la disponibilidad, la producción y el consumo de alimentos seguros.


Objectives: To analyze the iron intake in healthy adults of Medellín according to demographics, and to determine the association between the consumption of iron and hemoglobin in this population. Materials and methods: Cross-sectional study in 109 subjects. We applied a semiquantitative survey of food consumption frequency source of iron given the frequency of consumption and portion. Summary measures, frequencies, Mann Whitney, Kruskal Wallis ANOVA and Spearman correlation were calculated. We used SPSS version 20.0, considering a significance level of 0.05. Results: The mean age subjects was 32, 64.2% were female, 81.6% with technical or university studies, 29.3% students and 43.9% of low socioeconomic status. We found a daily intake of 12.3 mg/day on average, 61% from non-heme iron. The total iron consumed was statistically higher in unemployed subjects than in workers, students and housewives. The heme iron intake was statistically higher in individuals with graduate. No statistically significant differences were observed when comparing iron consumption by sex, age group and hemoglobin. Conclusions: The low intake of iron is not influenced by sex or age group, but by occupation and education, and is a factor that cannot reduce the prevalence of iron and other micronutrients deficiencies. It requires to implement more and better strategies for nutrition education and increased availability, production and consumption of safe food.


Objetivos: analisar o consumo de ferro em adultos sãos de Medellín segundo aspectos demográficos e sua correlação com a hemoglobina. Materiais e métodos: estudo transversal correlativo em 109 sujeitos. Aplicou-se uma enquete semiquantitativa de frequência de consumo de alimentos fonte de ferro tendo em conta a frequência do consumo e a porção. Calcularam-se medidas de resumo e frequências, U de Mann Withney, H de Kruskal Wallis, Anova y correlação de Spearman. O anterior empregando SPSS versão 20.0, considerando um nível de significação estadística de 0,05. Resultados: a idade média foi 32 anos, 64,2% eram de gênero feminino, 81,6% com estudos técnicos ou universitários, 29,3% estudantes e 43,9 de estrato social baixo. Achou-se um consumo diário de 12,3mg/dia em média, 61% proveniente de ferro não-heme. O ferro total consumido foi estadisticamente maior em desempregados que em trabalhadores, estudantes e donas de casa. O consumo de ferro heme foi estadisticamente superior em indivíduos com pós-graduação. Não se observaram diferenças estadisticamente significativas ao comparar o consumo de ferro por gênero, estrato, grupo etário e quantificação de hemoglobina. Conclusões: a baixa ingestão do ferro não está influenciada pelo gênero nem o grupo etário, mas sim por ocupação e escolaridade, e é um fator que não permite diminuir as prevalências de deficiência de ferro e outros micronutrientes. Requere-se implementar mais e melhores estratégias de educação nutricional e de aumento da disponibilidade, a produção e o consumo de alimentos seguros.


Assuntos
Humanos , Ferro da Dieta , Hemoglobinas , Prevalência , Estudos Transversais , Inquéritos e Questionários , Análise de Variância , Colômbia
7.
Rev. Inst. Nac. Hig ; 44(2): 21-28, dic. 2013. tab, graf
Artigo em Espanhol | LILACS, LIVECS | ID: lil-746323

RESUMO

El principal producto derivado de la yuca en Venezuela es el casabe, el cual es valorado por su contenido calórico, riqueza en Fibra Dietética (FD) y minerales. En este estudio se determinó el efecto del consumo de diferentes variedades de casabe venezolano sobre la absorción de hierro, cobre y zinc, en un modelo experimental, con 20 ratas machos adultas, cepa Sprague Dawley, las cuales fueron divididas en 4 grupos: un control sin fibra y tres grupos experimentales en los que se sustituyó el almidón de maíz por una variedad de casabe, identificados por su procedencia como: “Casabe Miranda”, “Casabe Sucre” y “Casabe Amazonas”. Las dietas con inclusión de casabe tuvieron un mayor contenido mineral, en comparación con la dieta control. El contenido de FD total y su fracción soluble fueron significativamente mayores en las variedades de casabe Sucre y Amazonas (p<0,05). La inclusión de casabe a las dietas produjo un incremento significativo en la excreción fecal de hierro y cobre(p<0,05). La absorción de los minerales se incrementó para el hierro en las variedades Miranda (3,5%) y Sucre (6%); para el cobre en el grupo Amazonas (32%); mientras que el Zinc fue menos afectado en su absorción a lo largo del ensayo. Los resultados de este estudio señalan que el efecto de la adición de casabe a las dietas sobre la absorción de hierro, cobre y zinc, fue diferente para cada mineral y estuvo relacionado con la dieta que consumieron los animales, dependiendo de la variedad de casabe utilizada.


The main product from cassava in Venezuela is the Casabe, which is valued for its caloric content, and rich in dietary fiber (DF) and minerals. This study determined the effect of consumption of different varieties of Venezuelan cassava on absorption of iron, cooper and zinc, in an experimental model, with 20 adult males rats, strain Sprague Dawley, which were divided into 4 groups: a control without fiber and three experimental groups with substitution of cornstarch by a variety of casabe, identified by their origin as:“ Casabe Miranda”, “Casabe Sucre” y “Casabe Amazonas”. Casabe diets had a higher mineral content, compared to the control diet. Total and soluble dietary fiber content were significantly higher in Sucre and Amazonas casabe varieties(p<0,05). The inclusion of casabe to diets resulted in a significant increase in the fecal excretion of iron and copper (p<0,05).The mineral absorption increased for iron in Miranda (3.5%) and Sucre (6%) varieties; for copper in the Amazonas group (32%); while the zinc absorption was less affected throughout the trial. The results of this study indicates that the effect of adding casabe to diets on absorption of iron, copper and zinc, was different for each mineral and was related to the diet consumed by the animals, depending of casabe variety used.


Assuntos
Humanos , Masculino , Feminino , Minerais na Dieta/metabolismo , Fibras na Dieta/análise , Ferro da Dieta/uso terapêutico , Minerais , Zinco , Saúde Pública , Cobre
8.
J Pediatr ; 163(2): 416-23, 2013 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-23452586

RESUMO

OBJECTIVE: To compare iron status in breastfed infants randomized to groups receiving complementary feeding regimens that provided iron from fortified infant cereals or meats, and to examine the development of the enteric microbiota in these groups. STUDY DESIGN: Forty-five exclusively breastfed 5-month-old infants were randomized to 1 of 3 feeding groups (FGs)-commercially available pureed meats, iron- and zinc-fortified infant cereals, or iron-only fortified infant cereals-as the first and primary complementary food through 9-10 months of age. Dietary iron was determined by monthly 3-day diet records. Iron status was assessed at the end of the study by measurements of hemoglobin, serum ferritin, and soluble transferrin receptor levels. In a subsample of 14 infants, enteric microbiota were profiled in monthly stool samples (5-9 months) by 16S ribosomal RNA gene pyrosequencing. RESULTS: Infants in the 2 cereal FGs had 2- to 3-fold greater daily iron intakes versus the meat FG (P < .0001). More than one-quarter (27%) of the infants had a low serum ferritin level, and 36% were mildly anemic, with no significant differences by FG; more infants in the meat FG had a high soluble transferrin receptor value (P = .03). Sequence analysis identified differences by time and FG in the abundances of several bacterial groups, including significantly more abundant butyrate-producing Clostridium group XIVa in the meat FG (P = .01) CONCLUSION: A high percentage of healthy infants who were breastfed-only were iron-deficient, and complementary feeding, including iron exposure, influenced the development of the enteric microbiota. If these findings are confirmed, then reconsideration of strategies to both meet infants' iron requirements and optimize the developing microbiome may be warranted.


Assuntos
Aleitamento Materno , Trato Gastrointestinal/microbiologia , Alimentos Infantis , Fenômenos Fisiológicos da Nutrição do Lactente , Deficiências de Ferro , Ferro da Dieta/administração & dosagem , Ferro/sangue , Metagenoma , Humanos , Lactente , Estado Nutricional
9.
J. pediatr. (Rio J.) ; J. pediatr. (Rio J.);85(5): 449-454, set.-out. 2009. graf, tab
Artigo em Português | LILACS | ID: lil-530123

RESUMO

OBJETIVO: Comparar a absorção do ferro da fórmula de partida e do leite de vaca integral fortificado. MÉTODOS: Foram utilizados 24 ratos machos Wistar recém-desmamados, mantidos em gaiolas metabólicas durante todo o período do experimento (10 dias). No primeiro dia, os animais foram distribuídos em três grupos semelhantes quanto ao peso, comprimento, hematócrito e hemoglobina: 1) fórmula de partida para lactentes; 2) leite de vaca integral em pó fortificado com a mesma quantidade e tipo de sal de ferro da fórmula; e 3) controle - leite de vaca integral em pó não fortificado com ferro. Água e dieta foram oferecidas ad libitum com mensuração do volume consumido. Peso, hematócrito e hemoglobina foram mensurados no quinto e no 10º dia do experimento, quando foram analisados também comprimento, sangue oculto nas fezes e teor de ferro hepático. RESULTADOS: O grupo 1 ingeriu menor volume de dieta (450,5±26,50 mL) que os grupos 2 (658,8±53,73 mL) e controle (532,7±19,06 mL; p < 0,001). As concentrações de hemoglobina foram maiores (p < 0,001) no grupo 1 (12,1±1,13 g/dL) que nos grupos 2 (9,6±1,59 g/dL) e controle (6,2±0,97 g/dL). O teor de ferro hepático apresentou o mesmo comportamento da hemoglobina (p < 0,001). Não foi observada diferença de peso e comprimento nos três grupos (p = 0,342). Não foi detectado sangue oculto nas fezes de nenhum dos animais. CONCLUSÕES: Apesar do menor volume ingerido, o grupo que recebeu fórmula apresentou maior absorção de ferro e concentração de hemoglobina que o grupo que recebeu leite de vaca integral fortificado. O crescimento foi semelhante nos três grupos.


OBJECTIVE: To compare iron absorption from infant formula and iron-fortified cow's milk. METHODS: Twenty-four weanling Wistar rats were maintained in metabolic cages during the whole experiment (10 days). On the first day, the animals were divided into three similar groups according to their weight, length, hematocrit and hemoglobin levels: 1) infant formula; 2) powdered whole cow's milk fortified with iron in the same quantity and type as the formula; 3) control - powdered whole cow's milk not fortified with iron. Deionized water and diet were offered ad libitum, and the volume consumed was measured. Weight, hematocrit, and hemoglobin levels were measured on the fifth and 10th days when length, fecal occult blood, and hepatic iron levels were also analyzed. RESULTS: Group 1 consumed less diet (450.5±26.50 mL) than group 2 (658.8±53.73 mL) and control group (532.7±19.06 mL, p < 0.001). Hemoglobin levels were higher (p < 0.001) in group 1 (12.1±1.13 g/dL) than in group 2 (9.6±1.59 g/dL) and in control group (6.2±0.97 g/dL). Hepatic iron level showed the same pattern as hemoglobin (p < 0.001). There was no difference in weight and length between the three groups (p = 0.342). There was no fecal occult blood in the any of the animals. CONCLUSIONS: Despite the lower volume consumed, the group that received formula presented higher iron absorption and hemoglobin levels than the group fed with fortified whole cow's milk. Growth was similar in the three groups.


Assuntos
Animais , Masculino , Ratos , Alimentos Fortificados , Fórmulas Infantis/química , Ferro da Dieta/administração & dosagem , Ferro/farmacocinética , Leite/química , Análise de Variância , Hemoglobinas/análise , Modelos Teóricos , Ratos Wistar , Estatísticas não Paramétricas , Desmame
10.
Rev. estomatol. Hered ; 18(1): 16-20, ene.-jun. 2008. ilus, tab
Artigo em Espanhol | LILACS, LIPECS | ID: lil-559642

RESUMO

El presente estudio tuvo como propósito conocer la asociación entre la presencia de pigmentaciones negras extrínsecas en superficies dentarias y la frecuencia de caries dental en niños con dentición mixta del Servicio de Odontopediatría del Hospital Central Fuerza Aérea del Perú (n=185), de los cuales el 6,49% (12 niños) presentaban dichas pigmentaciones. Para el análisis de los datos se emplearon frecuencias, porcentajes, medidas de tendencia central, medidas de dispersión, Chi-cuadrado y para conocer la asociación se empleó la prueba U de Mann Whitney. Al analizar la asociación entre las pigmentaciones negras extrínsecas y la frecuencia de caries dental, los resultados mostraron en los niños que presentaban dichas pigmentaciones un CEO+CPO de 1,33±1,07; mientras que los niños que no presentaban dichas pigmentaciones negras extrínseca sun CEO+CPO de 3,39±2,39. Sobre la base del análisis estadístico se concluye que el CEO+CPO en los niños con pigmentaciones negras extrínsecas fue menor que el CEO+CPO en los niños que no tenían dichas pigmentaciones siendo esta diferencia estadísticamente significativa con un p=0,001. Cabe resaltar que se encontró asociación entre la presencia de estas pigmentaciones y el consumo de suplementos dietéticos a base de fierro siendo estadísticamente significativa con un p=0,027.


The aim of the present study was to explore the association between the presence of extrinsic black stains on tooth surfaces and ithe frequency of dental caries in children from the Pediatric Clinic of the Peruvian Air Force Central Hospital (n=185). Among the children studied, 6,49% (12 children) presented those pigmentations. For the analysis of the data, frequencies, percentages, measures of central tendency, measures of dispersion and Chi-square were used and to explore the association Mann-Whitney U test was used, processed and analyzed using SPSS version 12 program. After the analysis of the relationship between the extrinsic black stains and the frequency of dental caries, the results showed that in children presenting such pigmentations the DMF+def index was of 1.33±1.07, while in children who did not present such black extrinsic pigmentations a DMF+def of 3.39±2.39 was found. Based on the statistical analysis it is concluded that the DMF+def in children with extrinsic black stains was lower than the DMF+def on children who had not such pigmentations and this difference was statistically significant with p=0.001. It is worth mentioning that an association found between the presence of these pigmentations and consumption of dietary supplements based on iron was statistically significant with p=0.027.


Assuntos
Humanos , Pré-Escolar , Criança , Cárie Dentária , Ferro da Dieta , Prevotella melaninogenica , Suplementos Nutricionais , Estudos Transversais
11.
Cad. saúde pública ; Cad. Saúde Pública (Online);24(supl.2): s303-s311, 2008. tab
Artigo em Português | LILACS | ID: lil-487393

RESUMO

Esse estudo teve como objetivo investigar a efetividade da suplementação semanal de ferro na concentração de hemoglobina, no estado nutricional e no desenvolvimento mental e motor de lactentes em quatro creches municipais do Recife, Pernambuco, Brasil. O estudo consistiu de uma intervenção do tipo antes-depois realizada com suplementação semanal com ferro por seis meses, em uma amostra de 76 crianças com idade entre 4 e 24 meses, no período de fevereiro a dezembro de 2005. Os desenvolvimentos mental e motor foram avaliados pela Escala de Desenvolvimento Infantil de Bayley II. Após a suplementação observou-se um aumento significante na concentração de hemoglobina, apenas no grupo de lactentes com hemoglobina inicial < 9,5g/dL (p = 0,001). Para o índice peso/comprimento também se verificou um incremento significante da média de escore z, no entanto, ocorreu o oposto para o índice comprimento/idade. Não se observou diferença nos índices de desenvolvimento. Conclui-se que a suplementação semanal de ferro foi efetiva elevando a hemoglobina nos lactentes com níveis iniciais mais baixos, não se observando impacto no desenvolvimento infantil.


This study analyzed the effectiveness of weekly iron supplementation on hemoglobin concentration, nutritional status, and mental and motor development of infants at four public daycare centers in Recife, Pernambuco State, Brazil. This was a before-after intervention study conducted with weekly iron supplementation for six months in a sample of 76 infants in the 4 to 24 month age group, from February to December 2005. Mental and motor development was assessed through the Bayley Scale of Infant Development II. After supplementation, a significant increase was observed in hemoglobin concentration in the group of infants with initial hemoglobin level < 9.5g/dL (p = 0.001). There was also a significant increase in the mean weight-for-length z-score, but the opposite was found for length-for-age. No difference was observed in the developmental indices. We conclude that weekly iron supplementation was effective for increasing hemoglobin concentration in infants with lower initial levels, but no impact on infant development was observed.


Assuntos
Pré-Escolar , Humanos , Lactente , Desenvolvimento Infantil/efeitos dos fármacos , Suplementos Nutricionais , Hemoglobinas/análise , Ferro da Dieta/administração & dosagem , Estado Nutricional/efeitos dos fármacos , Anemia Ferropriva/diagnóstico , Anemia Ferropriva/tratamento farmacológico , Brasil , Creches , Desenvolvimento Infantil/fisiologia , Estado Nutricional/fisiologia , Fatores Socioeconômicos
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