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A hipersensibilidade dentinária (HD) é definida como uma dor aguda, de curta duração, que ocorre em resposta à estímulos externos direcionados a áreas de dentina exposta. Esta revisão sistemática objetivou avaliar a literatura disponível quanto à conformidade dos ensaios clínicos randomizados (ECRs) sobre tratamentos de HD com a Declaração CONSORT, além de realizar um mapeamento de suas características (tipo de intervenção, métodos de avaliação de sensibilidade, escalas utilizadas, modo de aplicação etc.), e analisar o risco de viés destes mesmos estudos. Apenas ECRs entraram nesta revisão. Foi traçada uma estratégia de busca específica para cada bases de dados: MEDLINE via PubMed, Scopus, Web of Science, LILACS, Biblioteca Brasileira em Odontologia (BBO) e EMBASE, além das buscas manuais. A análise e coleta de dados foram realizadas por dois revisores independentes que selecionaram os estudos em potencial primeiro pelo título e resumo e, após, pela leitura completa dos selecionados. Os artigos foram avaliados quanto à conformidade ao CONSORT em uma escala: 0 = sem descrição, 1 = descrição deficiente e 2 = descrição adequada, para cada item. Análise do risco de viés dos artigos foi realizada através da plataforma The Risk Of Bias Tool 2.0. Análises descritivas também foram realizadas. Dos 3078 artigos analisados, 2867 foram excluídos por não atenderem aos critérios de inclusão, não apresentarem comparação entre tratamentos ou não serem ECRs. Após as exclusões, 211 ECRs permaneceram para avaliação. Os periódicos que mais contribuíram foram o American Journal of Dentistry (13,7%) e Journal of Dentistry (8,5%). Os países com mais publicações foram a Índia (24,6%), seguido pelo Brasil (17,5%). Quanto à pontuação dos artigos para cada item CONSORT analisado, 92,42% dos artigos obtiveram pontuação máxima em "Elegibilidade", demonstrando haver uma descrição clara dos critérios de elegibilidade para participantes na maioria dos estudos. O item com menor quantidade de artigos com pontuação máxima foi "Tamanho do efeito estimado" (25,6%), demonstrando uma certa dificuldade dos autores em descrever adequadamente o tamanho do efeito estimado do(s) desfecho(s) e sua precisão com um intervalo de confiança de 95%. A maioria dos artigos apresentou risco "incerto" de viés. Com as análises feitas, concluiu-se que a adesão dos ECRs ao CONSORT requer mais atenção, uma vez que seguir suas diretrizes pode, a longo prazo, resultar em uma melhoria significativa dos relatos de ECRs, o que acarretará inúmeros benefícios tanto para a ciência acerca do tema, quanto para a posterior aplicação clínica (AU)

Dentin hypersensitivity (DH) is defined as an acute, short-term pain that occurs in response to external stimuli directed at areas of exposed dentin. This systematic review aimed to assess the available literature regarding the compliance of randomized clinical trials (RCTs) on DH treatments with the CONSORT statement, in addition to mapping their characteristics (type of intervention, sensitivity assessment methods, scales used, application mode, etc.), and to analyze the risk of bias of these same studies. Only RCTs were included in this review. A specific search strategy was designed for each of the following databases: MEDLINE via PubMed, Scopus, Web of Science, LILACS, Brazilian Dental Library (BBO) and EMBASE, in addition to manual searches. Data analysis and collection were performed by two independent reviewers who selected the potential studies at first by title and abstract, then by complete reading of the selected ones. Articles were evaluated for compliance with the CONSORT statement on a scale: 0 = no description, 1 = deficient description and 2 = adequate description, for each item. Analysis of the risk of bias was performed using The Risk Of Bias Tool 2.0. Descriptive analyzes were also performed. Among the 3078 articles analyzed, 2867 were excluded because they did not meet the inclusion criteria, did not present a comparison between treatments, or were not RCTs. After deletions, 211 RCTs remained for evaluation. The journals that most contributed were the American Journal of Dentistry (13.7%), Journal of Dentistry (8.5%%) and the Journal of Clinical Dentistry (7.1%). India (24.6%) and Brazil (17.5%) were the countries with the most publications. As for the score received by the articles for each CONSORT item analyzed, 92.42% of the articles obtained the maximum score in "Eligibility", demonstrating that there is a clear description of the eligibility criteria for participants in most studies. The item with the lowest number of articles with the maximum score was "Estimated effect size" (25.6%), demonstrating a particular difficulty for authors to adequately describe the estimated effect size of the outcomes and its precision with a confidence interval of 95%. Most articles presented an "uncertain" risk of bias. After these analyses, it was concluded that the adherence of RCTs to CONSORT requires more attention, since following its guidelines can, in the long term, result in a significant improvement in RCT reports, which may bring numerous benefits both to the science on the subject, as well as for the clinical application of what is being studied. (AU)

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Abstract Objective This study aimed to evaluate whether the use of desensitizing dentifrices containing obliterating agents can affect bond strength of eroded/abraded dentin. Methodology A total of 100 dentin samples were obtained from human molars. The teeth were cut into 3 mm-thickness discs and allocated in five groups (n=20), according to the toothpaste used: WoF - abrasion with fluoride-free toothpaste (Cocoricó); Arg - toothpaste containing arginine (Colgate Sensitive Pro-Relief); Nov - calcium sodium phosphosilicate toothpaste (Sensodyne Repair and Protect); SnF - fluoride-containing toothpaste (AmF/SnCl2/SnF2 - Elmex Erosion); and Control (no erosive/abrasive process). The erosive/abrasive cycle consisted of immersion in citric acid (1%, pH 2.6, 5 min, 4×/day) and abrasion (2×/day, 120-20 sec abrasion, 100 sec immersion) with each toothpaste. During intervals, samples were immersed in artificial saliva. This cycle was performed for five days. Two resin cylinders (2 mm in diameter) were constructed on each sample for the shear bond strength test using a universal adhesive system. The self-etch and etch-and-rinse (Scotchbond Universal) strategies were employed, each in half of the total sample (n=10). Bond strength (MPa) was measured in a shear test and failure modes were assessed with a stereomicroscope. Statistical analysis was performed using the two-way analysis of variance (ANOVA) and Tukey tests (p<0.05). Results A statistically significant difference was found between the adhesive strategies tested (p<0.001), with the self-etching form showing higher values than the etch-and-rinse. Moreover, no significant differences were observed between the tested toothpastes (p=0.750) and interactions (p=0.438). Conclusion The use of toothpaste containing obliterating agents does not affect bond strength to dentin subjected to erosive/abrasive conditions when a universal adhesive is used. However, the self-etch strategy might be preferred for eroded/abraded dentin.

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The sealing and bonding characteristics of luting cements may be affected by the application of desensitizers containing ingredients that induce chemical interaction with dentin organic matrix. This study evaluated the effect of different desensitizers on the immediate and long-term shear bond strength (SBS) of a self-adhesive resin cement (SARC) to dentin. Healthy bovine dentin specimens were used for the study. Gluma® Desensitizer, Desensibilize Nano P®, and Soothe® desensitizer were used in study groups, while the control group did not receive any treatment. Next, SARC (RelyXTM U200) in cylindrical mold was applied to the sample surface. All specimens were stored at 37 °C for 24 h or six months and tested for SBS. Additionally, water contact angle was measured using an optical tensiometer. Results were analyzed by analysis of variance and Student-t tests (p ˂ 0.05). Application of the different types of desensitizers had no significant influence on immediate or long-term SBS of SARC to dentin (p > 0.05). Differences for water contact angle were not statistically significant among the tested groups (p = 0.450). Within the limitations of the present study, it can be concluded that the application of the different types of desensitizers had no significant influence on the SBS of a SARC to dentin.

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OBJECTIVES: To evaluate the effect of photobiomodulation with low-level laser therapy (PBM-LLLT) combined with 5% potassium nitrate (KNO3) on controlling tooth sensitivity (TS) after in-office tooth bleaching. MATERIALS AND METHODS: Fifty volunteers were selected based on the inclusion and exclusion criteria and were randomly allocated into four groups: G1 (control): placebo gel application, 35% hydrogen peroxide bleaching (HP35) and mock PBM-LLLT without light emission; G2: placebo gel application, bleaching with HP35 and PBM-LLLT; G3: application of KNO3, bleaching with HP35 and mock PBM-LLLT; and G4: application of KNO3, bleaching with HP35 and PBM-LLLT. A pain assessment questionnaire was used to evaluate TS during the 21 days of treatment. The Friedman test was used for intragroup analysis, and the Wilcoxon and Mann-Whitney tests were used for intergroup comparisons. RESULTS: The intragroup evaluation showed significant differences among the evaluation times in all groups (p ≤ 0.05). The highest pain sensitivity levels were recorded on the 1st, 8th, and 15th days. In G1, TS manifested for up to 3 days after each bleaching session, while G2, G3, and G4 presented TS only on the days of the bleaching sessions. Intergroup analysis showed that TS manifestation differed significantly between G1 and the other groups (p ≤ 0.05) but did not differ significantly among G2, G3, and G4 (p ≥ 0.05). CONCLUSION: PBM-LLLT and KNO3 are effective at reducing pain sensitivity after tooth bleaching, but no synergistic effect between these treatments was observed for the different evaluation periods. CLINICAL RELEVANCE: The effect of PBM-LLLT combined with KNO3 on post-bleaching tooth sensitivity is similar to their individual use alone.

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This study aims to evaluate the association between Nd:YAG laser (with and without a photoabsorber) and two desensitizing dentifrices containing 15% NovaMin or 8% arginine, as potential treatments for dentin hypersensitivity (DH). DH was simulated by EDTA application for 2 min. Specimens were then analyzed with an environmental scanning electron microscope (ESEM) to ensure open dentin tubules (ODT), counted by using ImageJ software. Specimens were randomized into eight groups (n = 10): Laser (L), Laser+Photoabsorber (LP), Arginine (A), Arginine+Laser (AL), Arginine+Laser+Photoabsorber (ALP), NovaMin (N), NovaMin+Laser (NL), and NovaMin+Laser+Photoabsorber (NLP). Laser irradiation was performed with 1 W, 100 mJ, 10 Hz, ≅85 J/cm2; 4 irradiations of 10 s each, with 10 s intervals between them. After treatment, specimens were again analyzed by ESEM and submitted to erosive/abrasive cycling for 5 days. A final ESEM analysis was performed. Data were analyzed with two-way repeated measure ANOVA and Tukey tests (α = 0.05). After treatment, groups N, NL, and NLP presented the lower number of ODT, but they did not different from LP, ALP, and AL. Group A presented the highest number of ODT and it did not differ from group L. Groups L, AL, ALP, and LP presented intermediate results, without differing from each other. After cycling, group A presented the highest number of ODT and did not differ significantly from the other groups, except NLP. None of the associations tested presented better tubule occlusion than NovaMin by itself. Arginine was the only treatment that presented improved tubule occlusion when associated with Nd:YAG laser.

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