RESUMO
The role of iodine in ruminant reproductive function is well known. However, studies about the impact of this deficiency in reproductive performance of cattle are scarce. This paper describes stillbirth episodes in three beef cow herds in northwest Argentina. The stillbirth losses ranged between 15.8 and 25%. Grossly, the thyroid glands presented diffuse, bilateral and symmetric enlargement. Microscopically, follicular epithelium showed severe hyperplasia and hypertrophy, forming multiple stratified layers of large cuboidal cells, with papillary projections into the follicular lumen. Free thyroxine (T4f) mean levels in serum from aborted cows and heifers was 0.63±0.05 ng/dl. A diagnosis of congenital goiter was performed based on these findings. Following the diagnosis, the herds were supplemented orally and parentally with iodine. Mean T4f level post-treatment was 0.80±0.05 ng/dl and the stillbirth rate dropped sharply.
Assuntos
Animais , Bovinos , Bócio/congênito , Bócio/veterinária , Deficiência de Iodo/diagnóstico , Morte Perinatal , Natimorto/veterinária , Iodo/administração & dosagem , Tironinas , TiroxinaRESUMO
The role of iodine in ruminant reproductive function is well known. However, studies about the impact of this deficiency in reproductive performance of cattle are scarce. This paper describes stillbirth episodes in three beef cow herds in northwest Argentina. The stillbirth losses ranged between 15.8 and 25%. Grossly, the thyroid glands presented diffuse, bilateral and symmetric enlargement. Microscopically, follicular epithelium showed severe hyperplasia and hypertrophy, forming multiple stratified layers of large cuboidal cells, with papillary projections into the follicular lumen. Free thyroxine (T4f) mean levels in serum from aborted cows and heifers was 0.63±0.05 ng/dl. A diagnosis of congenital goiter was performed based on these findings. Following the diagnosis, the herds were supplemented orally and parentally with iodine. Mean T4f level post-treatment was 0.80±0.05 ng/dl and the stillbirth rate dropped sharply.(AU)
Assuntos
Animais , Bovinos , Bócio/congênito , Bócio/veterinária , Morte Perinatal , Natimorto/veterinária , Deficiência de Iodo/diagnóstico , Iodo/administração & dosagem , Tiroxina , TironinasRESUMO
A doença de Graves neonatal é observada em baixa porcentagem de crianças nascidas de mães portadoras dessa doença. Pode ser grave, com risco de morte e com efeitos deletérios sobre o desenvolvimento neural, embora seja geralmente autolimitada. A maioria dos recém-nascidos com hipertireoidismo pode melhorar rapidamente, desde que a terapia adequada seja logo iniciada, o que evita lesões sobre o sistema nervoso. (AU)
The neonatal Graves 'disease refers to hyperthyroidism, which is observed in a small percentage of children born to mothers with this disease. Although neonatal Graves' disease is usually self-limited, can be severe, life-threatening, and harmful effects on neural development. With appropriate therapy, started immediately, most newborns with hyperthyroidism may have improved rapidly, avoiding the negative consequences of hyperthyroidism in the developing nervous system. (AU)