RESUMO

A ingestão de Senecio spp. (maria-mole) é, possivelmente, a principal causa de morte de bovinos por agentes tóxicos nas regiões central e sul do Rio Grande do Sul. Ao considerar a limitação de informações acerca dessa condição no Oeste do Rio Grande do Sul, esse trabalho objetiva descrever os principais aspectos epidemiológicos e clínico-patológicos da seneciose em bovinos nessa região. O estudo foi realizado por meio da aplicação de questionários em 16 propriedades rurais de municípios da região que apresentaram casos suspeitos da intoxicação em bovinos, de agosto de 2011 a março de 2014. Durante as visitas as propriedades foram coletadas plantas do gênero Senecio para identificação botânica, bem como se procedeu a coleta de fragmentos de fígado através de biópsia transtorácica para confirmação da intoxicação. As espécies de Senecio mais frequentes nas propriedades foram S. brasiliensis e S. heterotrichius. De um total de 88 bovinos, de nove propriedades distintas, que apresentaram falha no ganho de peso, 69 animais (aproximadamente 80%) foram positivos para seneciose crônica por apresentarem lesões características da intoxicação, tais como fibrose periportal (78% dos casos), megalocitose (76% dos casos) e proliferação de ductos biliares (68% dos casos), classificadas entre discretas e acentuadas. O trabalho confirmou a ocorrência da doença, mesmo em bovinos sem sinais clínicos evidentes. Os resultados obtidos nessas avaliações foram fundamentais para orientar proprietários e técnicos quanto às principais características da doença e às formas de controle a serem adotadas. O emprego da biópsia hepática possibilitou o diagnóstico precoce da intoxicação e auxiliou os criadores quanto ao descarte mais criterioso de bovinos e a real situação da intoxicação no rebanho, minimizando as perdas econômicas.(AU)

The ingestion of Senecio spp. (ragwort) is perhaps the leading cause of death of cattle in central and southern Rio Grande do Sul, Brazil. Considering the limited information about this condition in the Western region of Rio Grande do Sul, Brazil, this paper describes main epidemiological clinical and pathological aspects of seneciosis in cattle. The assessments were made through questionnaires on 16 rural properties which had suspected cases of poisoning in cattle, from August 2011 to March 2014. During the visits were evaluated epidemiological aspects of poisoning and performed sample collection of Senecio plants for botanical identification, as well as collection of liver samples using transthoracic biopsy for confirmation of the poisoning. Senecio species most common on farms were S. brasiliensis and S. heterotrichius. From 88 cattle that failed to thrive on nine different farms, 69 animals (about 80%) were positive for chronic seneciosis with periportal fibrosis (78% of cases), megalocytosis (76% of cases) and with bile duct proliferation (68% of cases). Lesions were classified as mild, moderate or marked. The current study confirms the occurrence of this poisoning, even in cattle without evident clinical signs. The use of liver biopsy enabled the early diagnosis of poisoning and helped farmers carefully to dispose affectd cattle, as well as to recognize the real situation of poisoning in the herd and minimize economic losses.(AU)

Assuntos

RESUMO

A ingestão de Senecio spp. (maria-mole) é, possivelmente, a principal causa de morte de bovinos por agentes tóxicos nas regiões central e sul do Rio Grande do Sul. Ao considerar a limitação de informações acerca dessa condição no Oeste do Rio Grande do Sul, esse trabalho objetiva descrever os principais aspectos epidemiológicos e clínico-patológicos da seneciose em bovinos nessa região. O estudo foi realizado por meio da aplicação de questionários em 16 propriedades rurais de municípios da região que apresentaram casos suspeitos da intoxicação em bovinos, de agosto de 2011 a março de 2014. Durante as visitas as propriedades foram coletadas plantas do gênero Senecio para identificação botânica, bem como se procedeu a coleta de fragmentos de fígado através de biópsia transtorácica para confirmação da intoxicação. As espécies de Senecio mais frequentes nas propriedades foram S. brasiliensis e S. heterotrichius. De um total de 88 bovinos, de nove propriedades distintas, que apresentaram falha no ganho de peso, 69 animais (aproximadamente 80%) foram positivos para seneciose crônica por apresentarem lesões características da intoxicação, tais como fibrose periportal (78% dos casos), megalocitose (76% dos casos) e proliferação de ductos biliares (68% dos casos), classificadas entre discretas e acentuadas. O trabalho confirmou a ocorrência da doença, mesmo em bovinos sem sinais clínicos evidentes. Os resultados obtidos nessas avaliações foram fundamentais para orientar proprietários e técnicos quanto às principais características da doença e às formas de controle a serem adotadas. O emprego da biópsia hepática possibilitou o diagnóstico precoce da intoxicação e auxiliou os criadores quanto ao descarte mais criterioso de bovinos e a real situação da intoxicação no rebanho, minimizando as perdas econômicas.(AU)

The ingestion of Senecio spp. (ragwort) is perhaps the leading cause of death of cattle in central and southern Rio Grande do Sul, Brazil. Considering the limited information about this condition in the Western region of Rio Grande do Sul, Brazil, this paper describes main epidemiological clinical and pathological aspects of seneciosis in cattle. The assessments were made through questionnaires on 16 rural properties which had suspected cases of poisoning in cattle, from August 2011 to March 2014. During the visits were evaluated epidemiological aspects of poisoning and performed sample collection of Senecio plants for botanical identification, as well as collection of liver samples using transthoracic biopsy for confirmation of the poisoning. Senecio species most common on farms were S. brasiliensis and S. heterotrichius. From 88 cattle that failed to thrive on nine different farms, 69 animals (about 80%) were positive for chronic seneciosis with periportal fibrosis (78% of cases), megalocytosis (76% of cases) and with bile duct proliferation (68% of cases). Lesions were classified as mild, moderate or marked. The current study confirms the occurrence of this poisoning, even in cattle without evident clinical signs. The use of liver biopsy enabled the early diagnosis of poisoning and helped farmers carefully to dispose affectd cattle, as well as to recognize the real situation of poisoning in the herd and minimize economic losses.(AU)

Assuntos

RESUMO

Background: Lobular dissecting hepatitis (LDH) is a rare condition of unknown etiology occurring in individuals or in litters of young dogs from some breeds, having poor prognosis and short survival time. Clinically, ascites, weight loss, anorexia, diarrhea and acquired portosystemic shunts are present. Hepatic encephalopathy may also occur. Biochemical blood tests usually show elevated ALT levels. Macroscopically, the liver shows changes in volume, color and regeneration nodules. Histologically, dissection of the parenchyma by connective tissue proliferation leads to disorganization of the liver architecture. The aim of this article is report LDH in two Golden Retriever dogs genetically unrelated.Cases: Two dogs genetically unrelated and of different owners - Golden Retriever breed - were referred to the Veterinary Medical Teaching Hospital of the Universidade Luterana do Brasil (ULBRA). The first case was a female with 17 months of age and the second, brought to examination one year later, was a male with nine months of age. The clinical signs, in both animals were similar, consisting in intense prostration, inapetence, caquexia and ascites for approximately two weeks. The female dog presented also ataxia, convulsion and diarrhea. Blood examination showed, for both dogs, arregenerative anemia, normal levels of alanine aminotransferase (ALT) and elevated levels of alkaline phosphatase. Total serum protein and albumin were also reduced. Both dogs were euthanized due to their critical condition. The necropsy showed similar lesions in both animals: approximately one liter of a free red colored fluid was observed in the abdominal cavity and hepatic changes consisting in pale green color, smooth surface, firm consistence, yellowish nodules at the surface and tissue proliferation at the margins. There was also congestion of the abdominal visceral veins (portal shunts)...

Assuntos

RESUMO

Background: Lobular dissecting hepatitis (LDH) is a rare condition of unknown etiology occurring in individuals or in litters of young dogs from some breeds, having poor prognosis and short survival time. Clinically, ascites, weight loss, anorexia, diarrhea and acquired portosystemic shunts are present. Hepatic encephalopathy may also occur. Biochemical blood tests usually show elevated ALT levels. Macroscopically, the liver shows changes in volume, color and regeneration nodules. Histologically, dissection of the parenchyma by connective tissue proliferation leads to disorganization of the liver architecture. The aim of this article is report LDH in two Golden Retriever dogs genetically unrelated.Cases: Two dogs genetically unrelated and of different owners - Golden Retriever breed - were referred to the Veterinary Medical Teaching Hospital of the Universidade Luterana do Brasil (ULBRA). The first case was a female with 17 months of age and the second, brought to examination one year later, was a male with nine months of age. The clinical signs, in both animals were similar, consisting in intense prostration, inapetence, caquexia and ascites for approximately two weeks. The female dog presented also ataxia, convulsion and diarrhea. Blood examination showed, for both dogs, arregenerative anemia, normal levels of alanine aminotransferase (ALT) and elevated levels of alkaline phosphatase. Total serum protein and albumin were also reduced. Both dogs were euthanized due to their critical condition. The necropsy showed similar lesions in both animals: approximately one liter of a free red colored fluid was observed in the abdominal cavity and hepatic changes consisting in pale green color, smooth surface, firm consistence, yellowish nodules at the surface and tissue proliferation at the margins. There was also congestion of the abdominal visceral veins (portal shunts)...(AU)

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RESUMO

Se realizó un estudio descriptivo y transversal de 60 pacientes con cirrosis hepática, asistidos en el Hospital Provincial Docente Clinicoquirúrgico "Saturnino Lora Torres" de Santiago de Cuba, desde enero del 2009 hasta diciembre del 2011, con vistas a evaluarles desde el punto de vista nutricional. En la serie predominaron el sexo masculino (53,3 %), el grupo etario de 35-60 años (58,3 %), la evolución clínica de menos de 10 años (55,0 %) y el alcohol como causa de la afección (35,0 %); de igual modo, 54,9 % de los afectados presentaban grados diferentes de desnutrición, la cual fue más grave en quienes adquirieron la enfermedad por consumo alcohólico. Los parámetros de laboratorio más alterados se observaron en las cifras de albúmina, colesterol y hemoglobina, así como en las pruebas de inmunorreactividad cutánea, en ese orden. Para dar por concluido, los mayores grados de desnutrición se asociaron al alcohol como causa de la hepatopatía y al estadio avanzado de esta.

A descriptive and cross-sectional study of 60 patients with hepatic cirrhosis, attended in "Saturnino Lora Torres" Teaching Clinical Surgical Provincial Hospital in Santiago de Cuba was carried out from January, 2009 to December, 2011, aimed at evaluating them from the nutritional point of view. The male sex (53.3%), the age group 35-60 years (58.3%), the clinical course of less than 10 years (55.0%) and the alcohol as cause of the disorder (35.0%) prevailed in the series; likewise, 54.9% of those affected presented different degrees of malnutrition, which was more serious in those who acquired the disease due to alcoholic consumption. The most altered laboratory parameters were observed in the albumin, cholesterol and hemoglobin levels, as well as in the tests for cutaneous immunorreactivity, in that order. To concluded, the highest degrees of malnutrition were associated with the alcohol as cause of the hepatopathy and to its advanced stage.

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