RESUMO
Introduction: Protein-caloric malnutrition is a public health concern in certain areas of the Brazil. It can affect growth, the auditory nervous system development and, consequently, the cognition. This study compared the Brainstem Auditory Evoked Potential (BAEP) between malnourished and eutrophic children.Methods: A total of 111 children, aged 0-60 months, were examined: 57 were malnourished, according to the World Health Organization criteria, and 54 were normo-nourished. All the subjects underwent otorhinolaryngological evaluations and had acoustic immittance and transient evoked otoacoustic emissions within the normal range. The BAEP responses to click and tone burst stimuli were recorded at intensities of 80, 60, 40, and 30 dBNA.Results: We observed that latencies of I, III, and V waves and interpeaks III-V at 80 dBNA with click stimuli were significantly higher in all malnourished children when compared to those in the eutrophic children, as was the I-V interval in the 0- to 24-month group. The V-wave latencies at those intensities were also significantly higher in malnourished children.Conclusions: Malnourished children presented changes in BAEP characterized by delayed wave latency and interpeak intervals when compared to eutrophic children, suggesting alterations in both peripheral and central auditory pathways development and maturation.
Assuntos
Encéfalo/crescimento & desenvolvimento , Potenciais Evocados Auditivos do Tronco Encefálico/fisiologia , Desnutrição/fisiopatologia , Encéfalo/fisiopatologia , Brasil , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Sistema Nervoso , Estado Nutricional/fisiologiaRESUMO
OBJECTIVES: Assessing infants' hearing is of utmost importance, as hearing at this phase is required for the development of oral language. Through hearing, human beings are capable of developing communication. The Brainstem Auditory Evoked Potentials are an indispensable test to diagnose deafness in infants. This study aimed to analyze the results of the Brainstem Auditory Evoked Potentials in children with risk factors for hearing loss. METHODS: This cross-sectional study analyzed the Brainstem Auditory Evoked Potentials in 123 infants aged 1 to 24 months at a hearing health care service. The Vivosonic Integrity V500 equipment, which enabled the child to be awake while the testing was carried out, was used in this study. The data were compared by gestational age and sex, according to the standards suggested in the equipment handbook. RESULTS: A significant difference was verified for age ranges 4 to 6 months, 13 to 15 months (waves I and V), and 7 to 9 months (wave V). The lower values in absolute wave latencies were comparable to data from the equipment handbook, justifying the need for standardization of the screening process. CONCLUSION: There are some differences between the standards in the equipment handbook and those observed in our study. These results will serve as a reference for the standardization of the equipment used in the hearing health care service.
Assuntos
Humanos , Lactente , Pré-Escolar , Criança , Adolescente , Adulto , Adulto Jovem , Potenciais Evocados Auditivos do Tronco Encefálico , Perda Auditiva/diagnóstico , Estudos Transversais , Atenção à Saúde , AudiçãoRESUMO
BACKGROUND: The aim of this study was to analyze whether late-onset fetal growth restriction (FGR) alters regulatory capability in infants, and whether this can be detected using both the neonatal behavior assessment scale (NBAS) and brainstem auditory-evoked potentials (BAEP). METHODS: The diagnosis of FGR was made on Doppler examination in the third trimester of pregnancy. NBAS and BAEP measurement were performed at 1 month of corrected postnatal age. RESULTS: The group with late-onset FGR was integrated with 17 infants and the control group consisted of 14 subjects. The NBAS range of state score, which reflects organization of behavioral state, was low in infants with late-onset FGR. No differences were found in BAEP between groups. No association between NBAS and BAEP was detected. CONCLUSION: Late-onset FGR has a deleterious effect on NBAS range of state, but possibly does not alter BAEP response. It is proposed that regulatory capabilities in the neonatal period play a primary role in subtle cognitive difficulties in infants with late-onset FGR in the long term.
Assuntos
Retardo do Crescimento Fetal/psicologia , Comportamento do Lactente , Adolescente , Adulto , Estudos Transversais , Potenciais Evocados Auditivos do Tronco Encefálico/fisiologia , Feminino , Retardo do Crescimento Fetal/diagnóstico , Retardo do Crescimento Fetal/epidemiologia , Seguimentos , Idade Gestacional , Humanos , Incidência , Recém-Nascido , Masculino , México/epidemiologia , Gravidez , Estudos Retrospectivos , Fatores de Tempo , Ultrassonografia Doppler , Ultrassonografia Pré-Natal , Adulto JovemRESUMO
Iron deficiency alters metabolism, neurotransmission, glial integrity and the cortical myelin layer, besides increasing myelinization time. Environmental stimulation (handling) improves morphological, biochemical, electrophysiological and behavioral aspects of both well-nourished and malnourished animals. The objective of the present study was to determine the effects of an irondeficient diet and of handling on the brainstem auditory evoked potential (BAEP) of rats during development. Ninety-six male rats were divided since birth into Well-nourished (W, 35 mg iron/kg) and Anemic (A, 4 mg iron/kg) groups, and subdivided into Handling (H) and No Handling (NH). Body weight, hemoglobin (Hb), hematocrit (Ht), latencies of waves I, II, III IV, I-IV interpeak interval, and response threshold to auditory stimuli were evaluated at 18, 22, and 32 days. W animals presented higher Hb and Ht levels than A animals at 18, 22 and 32 days. The animals presented longer latencies of waves I, II, III and IV and I-IV interpeak interval of BAEP at 18 than at 22 and 32 days, and AH18 rats presented longer latencies of waves I and II than AH22 and AH32 rats, and longer wave I latency than WH18 animals. Iron deficiency increased the latencies of BAEP waves, suggesting damage to the myelin layer, especially during the early development, and the effects of handling were more evident along time in anemic animals.