RESUMO

Solid-phase synthetic strategies toward the generation of libraries of biologically relevant molecules were developed using olefin cross-metathesis as a key step. It is remarkably the formal alkane metathesis based on a one-pot, microwave-assisted, ruthenium-catalyzed cross-metathesis and reduction to obtain Csp3-Csp3 linkages.

Assuntos

Alcanos/síntese química , Alcenos/química , Alcanos/química , Catálise , Micro-Ondas , Estrutura Molecular , Rutênio/química