1.
J Pediatr
; 136(2): 258-60, 2000 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-10657837
RESUMO
In 6 patients with Sjögren-Larsson syndrome (SLS), the urinary excretion of leukotriene B(4) (LTB(4)) and omega-hydroxy-LTB(4) was found to be highly elevated, whereas omega-carboxy-LTB(4) was absent. This abnormal pattern of urinary excretion of LTB(4) and its metabolites appears to be unique to patients with SLS and offers a new approach to the diagnosis of this disorder. Moreover, defective inactivation of LTB(4) might be of pathophysiologic significance in the disease.
Assuntos
Leucotrieno B4/urina , Síndrome de Sjogren-Larsson/urina , Estudos de Casos e Controles , Criança , Feminino , Humanos , Leucotrieno B4/metabolismo , Masculino , Síndrome de Sjogren-Larsson/diagnóstico , Síndrome de Sjogren-Larsson/imunologia
2.
J Pediatr
; 136(2): 261, 2000 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-10657838