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Introduction Dysphagia induced by radiotherapy in the head and neck region comprises a challenging scenario and sometimes difficult rehabilitation due to the severity of the adverse effects. Some resources such as electrical stimulation have emerged as an alternative to complement the therapeutic process, but there is still no consensus on its use. Objective The purpose of the present study was to evaluate, through a meta-analysis, the effect of electrical stimulation on the rehabilitation of dysphagia generated after head and neck cancer treatment. Data Synthesis Four randomized controlled trials with a total of 146 participants were included. The age of the participants was 58.37 ± 1.8 years old and there was a predominance of males. The time to start the intervention ranged from 50.96 ± 40.12 months after cancer treatment. The intervention showed great heterogeneity regarding the positioning of the electrodes, parameters, duration of the stimulus, number of sessions, and intensity. No difference was identified in the following aspects: oral transit time, hyoid elevation, penetration and/or aspiration after electrostimulation. The quality of the evidence ranged from very low to moderate and high risk of bias. Conclusion In this meta-analysis, we found weak evidence for small and moderate swallowing benefits in patients after radiotherapy for head and neck cancer in short-term clinical trials.
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Abstract Introduction Dysphagia induced by radiotherapy in the head and neck region comprises a challenging scenario and sometimes difficult rehabilitation due to the severity of the adverse effects. Some resources such as electrical stimulation have emerged as an alternative to complement the therapeutic process, but there is still no consensus on its use. Objective The purpose of the present study was to evaluate, through a meta-analysis, the effect of electrical stimulation on the rehabilitation of dysphagia generated after head and neck cancer treatment. Data Synthesis Four randomized controlled trials with a total of 146 participants were included. The age of the participants was 58.37 ± 1.8 years old and there was a predominance of males. The time to start the intervention ranged from 50.96 ± 40.12 months after cancer treatment. The intervention showed great heterogeneity regarding the positioning of the electrodes, parameters, duration of the stimulus, number of sessions, and intensity. No difference was identified in the following aspects: oral transit time, hyoid elevation, penetration and/or aspiration after electrostimulation. The quality of the evidence ranged from very low to moderate and high risk of bias. Conclusion In this meta-analysis, we found weak evidence for small and moderate swallowing benefits in patients after radiotherapy for head and neck cancer in short-term clinical trials.
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Human schistosomiasis is caused by helminths of the genus Schistosoma. Macrophages play a crucial role in the immune regulation of this disease. These cells acquire different phenotypes depending on the type of stimulus they receive. M1 macrophages can be 'classically activated' and can display a proinflammatory phenotype. M2 or 'alternatively activated' macrophages are considered anti-inflammatory cells. Despite the relevance of macrophages in controlling infections, the role of the functional types of these cells in schistosomiasis is unclear. This review highlights different molecules and/or macrophage activation and polarization pathways during Schistosoma mansoni and Schistosoma japonicum infection. This review is based on original and review articles obtained through searches in major databases, including Scopus, Google Scholar, ACS, PubMed, Wiley, Scielo, Web of Science, LILACS and ScienceDirect. Our findings emphasize the importance of S. mansoni and S. japonicum antigens in macrophage polarization, as they exert immunomodulatory effects in different stages of the disease and are therefore important as therapeutic targets for schistosomiasis and in vaccine development. A combination of different antigens can provide greater protection, as it possibly stimulates an adequate immune response for an M1 or M2 profile and leads to host resistance; however, this warrants in vitro and in vivo studies.
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Esquistossomose Japônica , Esquistossomose , Animais , Humanos , Ativação de Macrófagos , Esquistossomose/parasitologia , Esquistossomose Japônica/parasitologia , Macrófagos/parasitologia , Schistosoma mansoniRESUMO
Agenamyia Albuquerque, an endemic neotropical genus with two species, has been revised to include three new species: Agenamyia colombiana de Carvalho, Wolff & Fogaa sp. nov. from Envigado; Agenamyia maculata de Carvalho, Wolff & Fogaa sp. nov. from El Retiro; and Agenamyia timida de Carvalho, Wolff & Fogaa sp. nov. from Sopetrn, all localities in Antioquia, Colombia. This review presents an identification key for all species, including color images and illustrations of male and female terminalia. The distribution of all species is mapped and discussed.
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Dípteros , Muscidae , Masculino , Feminino , Animais , Distribuição Animal , América do SulRESUMO
Praziquantel (PZQ) is the drug of choice for the treatment of all forms of schistosomiasis, although its mechanisms of action are not completely understood. PZQ acts largely on adult worms. This narrative literature review describes what is known about the mechanisms of action of PZQ against schistosomes from in vitro and in vivo studies and highlights the molecular targets in parasites and immune responses induced in definitive hosts by this drug. Moreover, new therapeutic uses of PZQ are discussed. Studies have demonstrated that in addition to impacting voltage-operated Ca2 + channels, PZQ may interact with other schistosome molecules, such as myosin regulatory light chain, glutathione S-transferase, and transient receptor potential channels. Following PZQ administration, increased T regulatory type 1 (Tr1) cell differentiation and decreased inflammation were observed, indicating that PZQ promotes immunoregulatory pathways. Although PZQ is widely used in mass drug administration schemes, the existence of resistant parasites has not been proven; however, it is a concern that should be constantly investigated in human populations. In addition, we discuss studies that evaluate health applications of PZQ (other than helminth infection), such as its effect in cancer therapy and its adjuvant action in vaccines against viruses.
Assuntos
Anti-Helmínticos , Esquistossomose mansoni , Esquistossomose , Canais de Potencial de Receptor Transitório , Vacinas , Adulto , Animais , Humanos , Praziquantel/farmacologia , Praziquantel/uso terapêutico , Praziquantel/metabolismo , Esquistossomose/tratamento farmacológico , Schistosoma/metabolismo , Canais de Potencial de Receptor Transitório/metabolismo , Vacinas/metabolismo , Vacinas/farmacologia , Vacinas/uso terapêutico , Anti-Helmínticos/farmacologia , Anti-Helmínticos/uso terapêutico , Anti-Helmínticos/metabolismo , Schistosoma mansoniRESUMO
The present study aimed to evaluate the changes in peripheral blood glucose concentrations induced by Schistosoma mansoni infection in Holochilus sciureus rodents, a wild reservoir of the parasite. Glucose concentration was measured in the plasma of blood samples using a colorimetric enzymatic test. Biological parameters and S. mansoni burden in each rodent were also verified and correlated with glucose concentrations. A total of 76 H. sciureus were captured, out of which 20 (26%) were infected with S. mansoni (n=13 males and n=7 females). Although the parasite burden was comparable between the sexes, blood glucose concentration was lower in infected males and almost unchanged in females. Furthermore, histopathological data revealed that male rodents had a greater hepatic granulomatous inflammatory reaction than females. In addition, we also confirmed that the weight and total length of the analyzed animals had no effect on glucose levels. Therefore, natural infection with S. mansoni in H. sciureus may have a lower impact on glycemic homeostasis in females, which will help us understand the role of these rodents as reservoirs of S. mansoni.
Assuntos
Doenças dos Roedores , Esquistossomose mansoni , Animais , Glicemia , Feminino , Masculino , Roedores/parasitologia , Schistosoma mansoni , Esquistossomose mansoni/parasitologia , Esquistossomose mansoni/veterinária , SigmodontinaeRESUMO
RESUMO Objetivo Identificar a ocorrência de disfunções orofaciais em pacientes infantojuvenis com leucemia aguda, submetidos à quimioterapia de remissão. Métodos Em um período de 16 meses, 40 pacientes com leucemias agudas, entre 3 e 18 anos de idade, foram admitidos em um hemocentro no estado do Amazonas. Destes, 23 foram incluídos neste estudo transversal e submetidos à avaliação das funções orofaciais, por meio do Nordic Orofacial Test-Screening (NOT-S), entre o trigésimo (D30) e o trigésimo terceiro dia (D33) da fase de indução da remissão. A presença de manifestações orais também foi avaliada por meio de exame clínico. Resultados Disfunção orofacial foi observada em, aproximadamente, metade dos casos avaliados (n=11). Destes pacientes, todos tiveram o domínio Secura de Boca (VI) alterado e 81,8% (n=9) apresentaram alteração no domínio Mastigação e Deglutição (IV). Mucosites em lábios, língua, soalho e orofaringe foram as lesões orais mais encontradas após a fase de indução. Houve associação entre a ocorrência de lesões orais nos pacientes avaliados e a presença de disfunção orofacial, segundo o NOT-S (IC 95%, p-valor = 0,027). Conclusão Sugere-se que a disfunção orofacial seja frequente na fase de indução da remissão em pacientes infantojuvenis com leucemias agudas. Estudos sobre as disfunções orofaciais nessa população, bem como sua relação com as lesões orais são necessários para melhor esclarecimento e compreensão dos impactos funcionais.
ABSTRACT Purpose To Identify the occurrence of orofacial dysfunctions in young children and adolescents with acute leukemia who are undergoing remission chemotherapy. Methods Over a period of 16 months, 40 three to eighteen year -old patients with acute leukemia were admitted to the Amazonas State Hemocenter. Of these, 23 were included in the cross-sectional study and submitted to the evaluation of orofacial functions using the Nordic Orofacial Test-Screening, between D30 and D33 of the remission induction phase. The presence of oral manifestations was also evaluated via clinical examination. Results Orofacial dysfunction was observed in approximately half of the evaluated cases (n=11). Of these patients, all had alterations in the Dryness of the Mouth (VI) domain and 81.8% (n=9) showed alterations in the Chewing and Swallowing (IV) domain. Mucosites on lips, tongue, floor of the mouth and the oropharynx were the most commonly found oral lesions after the remission induction phase. According to the NOT-S, there was an association between the occurrence of oral lesions in the evaluated patients and the presence of orofacial dysfunction (95% CI, p-value = 0.027). Conclusion It is suggested that orofacial dysfunction is frequent in the remission induction phase in children and adolescents with acute leukemia. Studies regarding these orofacial dysfunctions in this population, as well as their relationship with oral lesions, are needed in order to fully understand their functional impact.
Assuntos
Humanos , Pré-Escolar , Criança , Adolescente , Manifestações Bucais , Sistema Estomatognático/efeitos dos fármacos , Leucemia/tratamento farmacológico , Leucemia/terapia , Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos , BrasilRESUMO
The present study aimed to evaluate the changes in peripheral blood glucose concentrations induced by Schistosoma mansoni infection in Holochilus sciureus rodents, a wild reservoir of the parasite. Glucose concentration was measured in the plasma of blood samples using a colorimetric enzymatic test. Biological parameters and S. mansoni burden in each rodent were also verified and correlated with glucose concentrations. A total of 76 H. sciureus were captured, out of which 20 (26%) were infected with S. mansoni (n=13 males and n=7 females). Although the parasite burden was comparable between the sexes, blood glucose concentration was lower in infected males and almost unchanged in females. Furthermore, histopathological data revealed that male rodents had a greater hepatic granulomatous inflammatory reaction than females. In addition, we also confirmed that the weight and total length of the analyzed animals had no effect on glucose levels. Therefore, natural infection with S. mansoni in H. sciureus may have a lower impact on glycemic homeostasis in females, which will help us understand the role of these rodents as reservoirs of S. mansoni.(AU)
Neste presente estudo, objetivou-se avaliar as alterações induzidas pela infecção natural de Schistosoma mansoni nas concentrações de glicose do sangue periférico de roedores Holochilus sciureus, reservatório silvestre do parasito. A dosagem da concentração de glicose foi realizada no plasma de amostras de sangue por meio de teste enzimático colorimétrico. Parâmetros biológicos e carga parasitária de S. mansoni também foram verificados em cada roedor e correlacionados com as concentrações de glicose. Um total de 76 H. sciureus foram capturados, dentre os quais 20 (26%) estavam infectados por S. mansoni (n=13 machos e n=7 fêmeas). Apesar da carga parasitária ter sido semelhante entre os sexos, as concentrações de glicose no sangue foram menores em machos naturalmente infectados e quase inalteradas em fêmeas. Além disso, os dados histopatológicos mostraram uma maior reação inflamatória granulomatosa hepática em roedores machos, quando comparados com as fêmeas. Adicionalmente, também foi confirmado que o peso e o comprimento total dos animas analisados não interferiram nos valores de glicose. Portanto, a infecção natural por S. mansoni em H. sciureus pode induzir menos impacto na homeostase glicêmica em fêmeas, o que pode ajudar a melhor entender o papel desses roedores como reservatórios de S. mansoni.(AU)
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Animais , Roedores/sangue , Schistosoma mansoni , Produtos Biológicos , Esquistossomose mansoni , Glucose , InfecçõesRESUMO
Melanocryptus Cameron, 1902 is a neotropical genus with 11 described species (Yu et al. 2016). The first three species of the genus were originally placed in different genera: Melanocryptus Cameron (1902), Lobocryptus Schmiedeknecht (1904) and Hoplophorina Szépligeti (1916). Townes Townes (1966) placed these species into a single taxon, Melanocryptus, and included the genus as part of the subtribe Mesostenina (apud Aguiar Santos, 2015). Despite this original placement, in 1970, Townes created an exclusive subtribe Melanocryptina for the genus.
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Himenópteros/classificação , Animais , Brasil , FlorestasRESUMO
The tribe Otteiini is a group of cave crickets, that were believed only to inhabit the Greater Antilles (Cuba, Cayman Islands, and Hispaniola). However, when reviewing and studying similar cave crickets in Mexico, their relationship was proven with island taxa, expanding their distribution to the continental area, from the Yucatan Peninsula to the Gulf and Northeast of Mexico. Herein, the genus Paracophus is divided, and three additional genera are described: Hubbellcophus n. gen., Venegascophus n. gen. and Hortacophus n. gen. Also, two additional species for Paracophus are described (P. victoriensis n. sp. and P. velazquezi n. sp.). Diagnoses for all genera and dichotomous keys for genera and species are provided. Finally, the taxonomic relationships between the insular and continental taxa of the tribe are discussed, and the different taxonomic placements they had over time, with some genera located in Phalangopsinae and Luzarinae (Phalangopsidae) and Pentacentrinae (Gryllidae).
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Gryllidae/classificação , Distribuição Animal , Animais , Cavernas , México , Índias OcidentaisRESUMO
In this study, three new species of Hyalella (Crustacea: Amphipoda: Hyalellidae) are described based on specimens collected in wetlands located in three freshwater ecoregions (Southeastern Mata Atlântica, Tramandaí-Mampituba and Laguna dos Patos) of the southern Brazilian Coastal Plain (states of Rio Grande do Sul and Santa Catarina). Hyalella minuana n. sp. was recorded in the southernmost region of the state of Rio Grande do Sul. This species is characterized by presenting smooth body surface, epimeral plates not acuminated, nine serrate setae on the inner face of gnathopod 1, and peduncle of uropod 3 with four cuspidate setae with accessory seta and without plumose seta on the margin of the telson. Hyalella lagoana n. sp. was recorded in the northern region of Rio Grande do Sul and southern region of Santa Catarina. This species shows body surface smooth, epimeral plates not acuminated, nine serrate setae on the inner face of gnathopod 1, peduncle of uropod 3 with five cuspidate setae with accessory seta, and telson with six cuspidate setae with accessory seta without plumose seta on the margins. Hyalella sambaqui n. sp. was recorded in the state of Santa Catarina. This species is characterized by presenting smooth body surface, epimeral plates not acuminated, six serrate setae on the inner face of gnathopod 1, peduncle of uropod 3 with three cuspidate setae with accessory seta, and telson with three cuspidate setae with accessory seta and four plumose setae on the margin of the telson. The new records elevates the known diversity of species of Hyalella in the Brazilian territory to 33 species (19 in the southern Brazilian region) and to 83 species in the Americas.
Assuntos
Anfípodes/anatomia & histologia , Anfípodes/classificação , Animais , Brasil , Água Doce , Áreas AlagadasRESUMO
Nematodes develop resistance to the most common commercially available drugs. The aim of this study was to identify and evaluate the action of protein exudates from Mimosa caesalpiniifolia, Leucaena leucocephala, Acacia mangium, and Stylosanthes capitata seeds on the gastrointestinal nematode Haemonchus contortus. The exuded proteins were precipitated, dialyzed, lyophilized, and assessed for their effect on egg hatching and artificial larval exsheathment inhibition. Proteome analysis of the protein extracts was also performed. Although no egg-hatching inhibition was observed, all exudates showed efficacy in inhibiting the larval exsheathment of H. contortus larvae with an EC50 varying from 0.61 to 0.26 mg P mL-1. Proteomic analysis revealed the presence of proteases, protease inhibitors, chitinases, and lectins among other proteins in the exudates. Most of the exuded proteins belong to the oxidative stress/plant defense and energy/carbohydrate metabolism functional clusters. This study concluded that the bioactive proteins from different classes exuded by seeds of M. caesalpiniifolia, L. leucocephala, A. mangium, and S. capitata show stage-specific inhibition against H. contortus.
Assuntos
Exsudatos e Transudatos/química , Fabaceae/química , Haemonchus/efeitos dos fármacos , Proteínas de Plantas/farmacologia , Sementes/química , Animais , Anti-Helmínticos/química , Anti-Helmínticos/farmacologia , Exsudatos de Plantas/químicaRESUMO
Objetivo: compreender as percepções dos imigrantes haitianos sobre os Determinantes Sociais da Saúde que impactam a vivência da imigração. Método: pesquisa qualitativa, do tipo pesquisa ação participante, fundamentada no Itinerário de Pesquisa de Paulo Freire, que constitui três fases: Investigação Temática; Codificação e Descodificação; Desvelamento Crítico. Realizou-se Círculo de Cultura, no segundo semestre de 2019, com a participação de 12 imigrantes haitianos, estudantes universitários, residentes no oeste de Santa Catarina, Brasil, após aprovação pelo Comitê de Ética em pesquisa. Resultados: nos diálogos emergiram duas temáticas para discussão como determinação social da saúde e doença: saúde do imigrante no Brasil; desafios de estudar e trabalhar. Conclusão: A iniquidade de acesso aos direitos, escasso tempo para dormir e praticar exercícios físicos, saudade do Haiti, dificuldade financeira, adaptação à cultura brasileira e discriminação foram apontados como fatores determinantes que afetam a saúde. Urge a necessidade da construção de políticas públicas que garantam os direitos dos imigrantes no Brasil.
Objective: to understand the perceptions of Haitian immigrants about the social determinants of health that impact on the experience of immigration. Method: this qualitative, participant action study was based on Paulo Freire's research itinerary, which consists of three phases: thematic research; encoding and decoding; and critical unveiling. A "culture circle" was held, after ethics committee approval, in the second half of 2019, with the participation of 12 immigrant Haitian university students residing in western Santa Catarina, Brazil. Results: in the dialogues, two themes emerged for discussion as representing the social determination of health and disease: immigrants' health in Brazil; and challenges of studying and working. Conclusion: inequity in access to rights, lack of time to sleep and exercise, homesickness for Haiti, financial difficulties, adaptation to Brazilian culture, and discrimination were identified as determinant factors that affect health. There is an urgent need to build public policies to guarantee immigrants' rights in Brazil.
Objetivo: comprender las percepciones de los inmigrantes haitianos sobre los determinantes sociales de la salud que impactan en la experiencia de la inmigración. Método: este estudio cualitativo de acción participante se basó en el itinerario de investigación de Paulo Freire, que consta de tres fases: investigación temática; codificación y decodificación; y revelación crítica. Se realizó un "círculo cultural", luego de la aprobación del comité de ética, en el segundo semestre de 2019, con la participación de 12 estudiantes universitarios haitianos inmigrantes residentes en el occidente de Santa Catarina, Brasil. Resultados: en los diálogos surgieron dos temas de discusión que representan la determinación social de la salud y la enfermedad: la salud de los inmigrantes en Brasil; y desafíos de estudiar y trabajar. Conclusión: la inequidad en el acceso a los derechos, la falta de tiempo para dormir y hacer ejercicio, la nostalgia por Haití, las dificultades económicas, la adaptación a la cultura brasileña y la discriminación fueron identificadas como factores determinantes que afectan la salud. Urge construir políticas públicas para garantizar los derechos de los inmigrantes en Brasil.
Assuntos
Humanos , Masculino , Feminino , Adulto , Adulto Jovem , Estudantes , Universidades , Emigrantes e Imigrantes , Determinantes Sociais da Saúde , Brasil , Coleta de Dados , Pesquisa Qualitativa , Haiti/etnologiaRESUMO
New treatment strategies for schistosomiasis should be evaluated, since resistant strains to the only available drug, Praziquantel, have already been described. Thus, we demonstrated antiparasitic effects of ethanolic extracts of Jatropha gossypiifolia and Piper arboreum on cercariae and adult worms of Schistosoma mansoni. The bioassays were performed at 0-10 000 µg mL-1 concentration for 0-72 h. Adult worms were stained with carmine to assess external and internal damage. The chemical screening was performed using high-performance liquid chromatography. P. arboreum displayed the best cercaricidal effect, with a 100% reduction in viability in just 60 min. The extract of J. gossypiifolia was more effective against adult worms, with 100% viability reduction of male and female worms after 12 and 24 h, respectively. P. arboreum and J. gossypiifolia were equally effective in inhibiting the oviposition of S. mansoni (93% reduction) and causing damage to internal and external structures in adult worms. Flavonoids were identified in both the extracts and phenolic compounds and amides only in P. arboreum. Thus, for the first time, it was proven that ethanolic extracts of P. arboreum and J. gossypiifolia leaves are biologically active against cercariae and adult worms of S. mansoni in vitro.
Assuntos
Antiparasitários/farmacologia , Cercárias/efeitos dos fármacos , Jatropha/química , Piper/química , Extratos Vegetais/farmacologia , Schistosoma mansoni/efeitos dos fármacos , Animais , Antiparasitários/química , Feminino , Masculino , Extratos Vegetais/química , Folhas de Planta/químicaRESUMO
Efficient snail production is essential for the proper maintenance of the Schistosoma mansoni life cycle in the laboratory. In order to improve the breeding of Biomphalaria glabrata under laboratory conditions, this study aimed to demonstrate the effectiveness of a handmade shell-based substrate on the physiological performance of B. glabrata. The shells used to make the substrate were cleaned, sterilized and macerated until a powder was obtained (yield of 92.3%). B. glabrata specimens were randomly assigned to three treatment groups: negative control group (NCG) exposed to a clay-only substrate; a positive control group (PCG) containing clay, oyster flour and calcium carbonate; and the test group (TG) with the shell-based substrate and clay. B. glabrata bred in the test group showed improved growth, sexual maturity, fertility, mortality rate, and shell morphology when compared to the NCG, and similar to the PCG. Therefore, the shell-based substrate proved to be efficient and has a low cost for the breeding of B. glabrata.
Assuntos
Biomphalaria , Cruzamento , Estágios do Ciclo de Vida , Animais , Fertilidade , Schistosoma mansoniRESUMO
The Taxonomic Collections Center of the Federal University of Minas Gerais (CCT-UFMG) has 223,653 insects catalogued, of which about 6,500 are beetles (Coleoptera). Most insects in the collection are from the southeastern region of Brazil. The collection also includes specimens from other regions and from other countries. A checklist of the flat-faced longhorn beetles (Cerambycidae, Lamiinae) deposited in the CCT-UFMG is presented. The available exemplars were identified using the literature or direct comparison with individuals from other scientific collections. The CCT-UFMG contains 254 specimens of Lamiinae that were identified to species level, comprising 100 species from 63 genera. This checklist includes a new country record of Aerenicopsis championi Bates, 1885 for Brazil and the following 26 new records for the state of Minas Gerais (Brazil): Apagomera bravoi Galileo Martins, 2009; Atrypanius conspersus (Germar, 1824); Callia axillaris (Dalman, 1823); Callia xanthomera Redtenbacher, 1867; Cacostola acuticauda Marinoni Martins, 1982; Cipriscola fasciata (Thomson, 1860); Colobothea centralis Monné, 1993; Colobothea rubroornata Zajciw, 1962; Desmiphora ornata Bates, 1866; Estola assimilis Breuning, 1940; Eupromerella griseofasciata (Fuchs, 1959); Hedypathes monachus (Erichson in Schomburg, 1848); Hesychotypa subfasciata Dillon Dillon, 1945; Hippopsis pubiventris Galileo Martins, 1988; Ischioderes oncideroides Dillon Dillon, 1945; Laticranium mandibulare Lane, 1959; Lesbates caviunas (Dillon Dillon, 1949); Nealcidion silvai Monné Delfino, 1986; Oncideres alicei Lane, 1977; Oreodera curiosa Galileo Martins, 2007; Phoebe phoebe (Lepeletier Audinet-Serville, 1825); Polyrhaphis olivieri Thomson, 1865; Psapharochrus geminus Galileo Martins, 2012; Psapharochrus nigricans (Lameere, 1885); Steirastoma breve (Sulzer, 1776); Tapeina rudifrons Marinoni, 1972. Photographs of specimens that represent new distribution records and a map showing the distribution of the species of Lamiinae present in the collection are provided.
Assuntos
Besouros , Animais , BrasilRESUMO
BACKGROUND & OBJECTIVES: Rickettsial and other zoonotic diseases are a latent risk for workers of veterinary clinics. The objective of this study was to evaluate the prevalence and the associated risk factors of parasitosis caused by Rhipicephalus sanguineus, and to estimate the seroprevalence of rickettsial diseases in workers of urban veterinary clinics of Juárez city, México. METHODS: The participants of the study were recruited from 63 private veterinary clinics and hospitals. The serological analysis of the blood samples collected was carried out using immunofluorescence assay (IFA). The statistical analysis for prevalences, risk factors, and correlation was performed with the SAS program. RESULTS: In total, 167 veterinary workers were included in the study. The prevalence of tick bites was 40% (67/167), and the risk factors associated with the occurrence of bites included the activities performed in the clinic and the number of labour hours spent per week. About 21% (35/167) of participants were seropositive to R. rickettsii, 28% (47/167) to Ehrlichia chaffeensis, and 24% (40/167) to Anaplasma phagocytophilum. A correlation was observed between: the number of workers in the clinics and the proportion of tick bites (r2 = 0.865); the prevalence of bites and the seropositivity of the participants to at least one pathogen (r2 = 0.924); and the number of bites per individual and infection to pathogens (r2 = 0.838). INTERPRETATION & CONCLUSION: Workers in urban veterinary clinics are highly exposed to tick bites and, therefore, to the diseases they transmit. Hence, it is important to implement prevention measures and perform constant monitoring of these diseases.
Assuntos
Pessoal de Saúde/estatística & dados numéricos , Infecções por Rickettsia/epidemiologia , Infecções por Rickettsia/imunologia , Picadas de Carrapatos/complicações , Doenças Transmitidas por Carrapatos/imunologia , População Urbana/estatística & dados numéricos , Adolescente , Adulto , Técnicos em Manejo de Animais/estatística & dados numéricos , Animais , Ehrlichiose/imunologia , Feminino , Hospitais Veterinários/estatística & dados numéricos , Humanos , Masculino , México/epidemiologia , Prevalência , Rhipicephalus sanguineus/imunologia , Infecções por Rickettsia/etiologia , Infecções por Rickettsia/transmissão , Fatores de Risco , Estudos Soroepidemiológicos , Picadas de Carrapatos/microbiologia , Doenças Transmitidas por Carrapatos/microbiologia , Médicos Veterinários/estatística & dados numéricos , Adulto Jovem , Zoonoses/imunologia , Zoonoses/microbiologia , Zoonoses/transmissãoRESUMO
One of the sequelae of head and neck cancer treatment is secondary lymphedema, with important impact on breathing, swallowing and vocal functions. The aim of the study was to assess the presence, staging characteristics and relationship of external and internal lymphedema and dysphagia after head and neck cancer treatment. The MDACC Lymphedema Rating Scale in Head and Neck Cancer was employed for the assessment and staging of face and neck lymphedema; the Radiotherapy Edema Scale for internal lymphedema; and a fiberoptic endoscopic evaluation of swallowing (FEES) for swallowing. The sample consisted of 46 patients with a diagnosis of head and neck cancer. Lymphedema was detected in 97.8% (45) of the evaluations with predominance of the composite type (73.9%-34). A high percentage of external lymphedema of the neck (71.7%-33) and submandibular (63%-29) were detected, with predominance of the more advanced levels. Internal edema was found in almost all structures and spaces at moderate/severe level. At FEES, residue (higher percentage in valleculae and pyriform sinus), penetration and aspirations were observed. The residue was detected in higher occurrence in patients with composite lymphedema (p = 0.012). The combined treatment with radiotherapy was related to submandibular external lymphedema (p = 0.009), altered pharyngolaryngeal sensitivity (0.040), presence of residue (p = 0.001) and penetration to pasty (p = 0.007) and internal edema in almost all structures. There was also a higher percentage of residue in cases with internal altered pharyngolaryngeal sensitivity, residue, penetration and aspiration. Combined treatment with radiotherapy is an associated factor of edema. Cervicofacial and pharyngolaryngeal lymphedema is a frequent event after treatment for HNC, with important impact on swallowing performance characterised by altered pharyngolaryngeal sensitivity, residue, penetration and aspiration. Combined treatment with radiotherapy is an associated factor.
Assuntos
Protocolos Antineoplásicos , Transtornos de Deglutição/epidemiologia , Neoplasias de Cabeça e Pescoço/terapia , Linfedema/epidemiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Antineoplásicos/efeitos adversos , Terapia Combinada , Transtornos de Deglutição/etiologia , Face/patologia , Feminino , Humanos , Laringe/patologia , Linfedema/etiologia , Masculino , Pessoa de Meia-Idade , Pescoço/patologia , Esvaziamento Cervical/efeitos adversos , Procedimentos Cirúrgicos Otorrinolaringológicos/efeitos adversos , Faringe/patologia , Lesões por Radiação/epidemiologia , Lesões por Radiação/etiologiaRESUMO
The original version of this article unfortunately contained a mistake. Figure 2 was repeated in Figure 3.
RESUMO
Plistonax Thomson, 1864 is a Neotropical genus of longhorned beetles (Cerambycidae: Lamiinae) currently composed of six species. Herein, we describe a new species (Plistonax albituberculatus Silva Júnior Souza sp. nov.) from Brazilian States of Rio de Janeiro and Bahia. We also propose the transference of Exalphus hefferni Audureau, 2017 to Plistonax, resulting in the following comb. nov.: Plistonax hefferni (Audureau, 2017).