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1.
Braz J Microbiol ; 55(1): 689-698, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38227116

RESUMO

The use of fungicides in the postharvest treatment of mangoes has been widespread due to the incidence of pathogens, but awareness of the health risks arising from their use has increased, driving the search for more sustainable treatments. This study aimed to evaluate the activity of antifungal treatment of seven essential oils (EO) against four fungi that cause postharvest diseases in mangoes and define the minimum inhibitory concentration (MIC) and chemical composition, analyzed by gas chromatography (GC-MS). The results showed that the EOs of oregano, rosemary pepper, cinnamon bark, and clove inhibited 100% of the mycelial growth of the studied pathogens, with MIC ranging from 250 to 2000 µL.L-1. The main compound found in oregano was carvacrol (69.1%); in rosemary and pepper oil, it was thymol (77.2%); cinnamaldehyde (85.1%) was the main constituent of cinnamon bark, and the eugenol (84.84%) in cloves. When evaluating the antifungal activity of these compounds, thymol and carvacrol showed greater inhibitory activity against fungi. Therefore, this study showed the great potential of oregano, clove, rosemary pepper, and cinnamon bark essential oil as alternative treatments to synthetic fungicides in controlling postharvest diseases in mangoes.


Assuntos
Cimenos , Fungicidas Industriais , Mangifera , Óleos Voláteis , Timol/farmacologia , Antifúngicos/farmacologia , Fungicidas Industriais/farmacologia , Óleos Voláteis/farmacologia , Óleos Voláteis/química , Fungos , Testes de Sensibilidade Microbiana
2.
Bull Environ Contam Toxicol ; 97(4): 528-35, 2016 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-27225508

RESUMO

Sulfamethazine (SMZ) is one of the most commonly used sulfonamide compounds in fish farming, and its physiological effects on fish are unknown. SMZ was administered to juvenile Nile tilapia (Oreochromis niloticus) at a dose level of 422 mg kg(-1) body weight, for a period of 11 days, via medicated feed. Fish were divided into two groups, the control group (CG) and the group fed with SMZ in feed. The administration of SMZ did not alter the erythrograms and leukograms of the Nile tilapia. The SMZ-fed group showed the same hepatic lipid peroxidation (LPO) concentration as the CG. Nonetheless, the oral administration of SMZ raised the hepatic catalase (CAT) and glutathione S-transferase (GST) activities, the increase probably being sufficient to prevent hepatic LPO production. The oral administration of SMZ affects the hepatic GST and CAT activities of Nile tilapia.


Assuntos
Ciclídeos/metabolismo , Dieta , Peroxidação de Lipídeos/efeitos dos fármacos , Fígado/efeitos dos fármacos , Fígado/enzimologia , Estresse Oxidativo/efeitos dos fármacos , Sulfametazina/toxicidade , Administração Oral , Animais , Anti-Infecciosos/toxicidade , Biomarcadores/metabolismo , Contagem de Células Sanguíneas , Catalase/metabolismo , Glutationa Transferase/metabolismo , Fígado/metabolismo , Sulfametazina/administração & dosagem
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