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2.
Fertil Steril ; 50(2): 337-42, 1988 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-3135207

RESUMO

Gonadotropin serum levels and pulsatile secretion of gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH) are regulated by sexual steroids and perhaps inhibin, but the relative rates of LH and follicle-stimulating hormone (FSH) secretion are modulated by the frequency of GnRH pulses. This study evaluated LH pulsatility in patients with idiopathic normogonadotropic oligospermia (INO) and normal men before and after clomiphene citrate (CC) administration. INO patients evidenced a lower mean LH levels (P less than 0.001), a higher mean pulse frequency (P less than 0.05) and similar pulse amplitude than normal men. CC induced in normal men a higher LH and testosterone (T) increments and increased pulse amplitude only in normal men. Estradiol (E2) showed no difference in either group. Patients with INO might evidence a hypothalamic disorder that may alter pulsatile GnRH secretion. A different response to CC in patients with INO seems to lend support to a primary hypothalamic lesion. A probable gonadotropin imbalance might alter intratesticular concentrations of T and E2 and be the cause of spermatogenic failure.


Assuntos
Hormônio Luteinizante/sangue , Oligospermia/sangue , Adulto , Gonadotropina Coriônica/farmacologia , Clomifeno/farmacologia , Estradiol/sangue , Hormônio Foliculoestimulante/sangue , Humanos , Masculino , Oligospermia/tratamento farmacológico , Hormônios Liberadores de Hormônios Hipofisários/sangue , Testosterona/sangue
3.
Nahrung ; 27(2): 125-8, 1983.
Artigo em Inglês | MEDLINE | ID: mdl-6855880

RESUMO

The nitrate and nitrite contents in cheese of the Gouda type, produced by the Milk Complex of Havanna, were investigated and compared with those found in 5 types of imported cheese consumed in Cuba. No significant differences were found in the mean value (mean) of NaNO3, whereas in the mean value (mean) of NaNO2 differences were found when comparing all cheeses against each other. From these results it is inferred that the consumption of Gouda type cheese does not represent an important contribution to the daily intake of nitrates and nitrites, precursors in the synthesis of cancerogenic N-nitroso compounds.


Assuntos
Queijo/análise , Nitratos/análise , Nitritos/análise , Nitrito de Sódio/análise , Cuba , Manipulação de Alimentos
8.
Bol Estud Med Biol ; 27(2): 71-5, 1971 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-5147452
9.
Bol Estud Med Biol ; 26(8): 365-9, 1970 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-4944820
10.
J Am Med Womens Assoc ; 24(5): 422-3, 1969 May.
Artigo em Inglês | MEDLINE | ID: mdl-4239458
16.
Annu Rev Pharmacol ; 6: 9-18, 1966.
Artigo em Inglês | MEDLINE | ID: mdl-5324863
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