RESUMO

A 32-year-old woman presented with progressive myalgia, bone pain, fatigue, insufficiency hip fractures, high urine phosphate, and low serum phosphate and vitamin D levels. These findings were suggestive of oncogenic osteomalacia. A whole-body Tc-octreotide scintigraphy with SPECT/CT showed uptake on a sclerotic intramedullary lesion in the left medial tibia plateau. MRI depicted a solid lesion. The lesion was surgically removed; the patient became asymptomatic, and follow-up laboratory results normalized. Histopathologic examination revealed a vascular hemangiopericytoma-like tumor, positive for somatostatin receptor (SSR-2). Whole-body Tc-octreotide scintigraphy with SPECT/CT may detect occult oncogenic osteomalacia tumors.

Assuntos

Neoplasias de Tecido Conjuntivo/diagnóstico por imagem , Neoplasias Primárias Desconhecidas/diagnóstico por imagem , Octreotida/análogos & derivados , Compostos de Organotecnécio , Compostos Radiofarmacêuticos , Tomografia Computadorizada de Emissão de Fóton Único , Tomografia Computadorizada por Raios X , Adulto , Feminino , Humanos , Imageamento por Ressonância Magnética , Imagem Multimodal , Neoplasias de Tecido Conjuntivo/secundário , Osteomalacia , Síndromes Paraneoplásicas