RESUMO
The aim of this study was to determine the prevalence of oxygen desaturation in adults aged>or=40 yrs as altitude above sea level increases. A population-based, cross-sectional study with a multistage cluster sampling of 1,063 subjects from metropolitan Mexico City (Mexico; 2,240 m above sea level), 1,357 from Caracas (Venezuela; 950 m) and 943 from Montevideo (Uruguay; 35 m). The mean of six measurements of arterial oxygen saturation (SP,O2) was estimated using a pulse oximeter. Mean SP,O2 decreased with altitude. No subject from Montevideo had a mean SP,O2
Assuntos
Altitude , Oxigênio/metabolismo , Oxigênio/uso terapêutico , Estudos Transversais , Feminino , Serviços de Assistência Domiciliar , Humanos , Masculino , México , Pessoa de Meia-Idade , Prevalência , Saúde da População UrbanaRESUMO
Despite advances in surgical modalities and chemotherapeutic agents, the 5-year survival for patients with advanced ovarian cancer is barely 40-50%. At the moment, optimally cytoreductive primary surgery is the best option for patients with advanced ovarian cancer. Predictive factors of primary optimum reduction surgery have been described based on imaging studies and tumor markers and based on the premise to know a priori the weight and tumor volume, with promising results. A retrospective study was conducted based on the hypothesis that it is feasible to identify those patients not susceptible of undergoing optimum primary cytoreductive surgery. The variables associated with a lesser probability of success in this study are the presence of palpable abdominal tumor on physical examination, the presence of tumor in Douglas' cul-de-sac on vaginal exploration, the presence of ascites in any quantity, elevation of CA-125 above 1000 U/l, and the presence of pulmonary and liver metastases. The success rate for cytoreduction was 62% when none or one of these variables was present and 32% when two or more variables were present.
Assuntos
Árvores de Decisões , Neoplasias Ovarianas/mortalidade , Neoplasias Ovarianas/cirurgia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Antígeno Ca-125/sangue , Intervalo Livre de Doença , Feminino , Procedimentos Cirúrgicos em Ginecologia , Humanos , Estudos Longitudinais , Prontuários Médicos , México/epidemiologia , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Neoplasias Ovarianas/patologia , Estudos Retrospectivos , Análise de SobrevidaRESUMO
It is suggested that the observed difference in duration of pregnancy between Blacks and Whites is partly physiological since it is not entirely explained by social inequities alone. This study compares women with well-defined gestational periods seeking attention at the Antoine Béclère Maternity Clinic. Group A consists of French women of European ancestry, Group B, those born in the French Antilles of mixed ancestry, and Group C black African women with insignificant European admixture. When compared to Group A, within each socio-economic class, group B and C have shorter gestational periods. These differences persist after adjustment for socio-economic variables, so that other explanations should be considered, specifically genetic determinants.
Assuntos
Etnicidade , Gravidez , África/etnologia , População Negra , Estatura , Peso Corporal , Europa (Continente)/etnologia , Feminino , França , Humanos , Martinica/etnologia , Fatores Socioeconômicos , Fatores de Tempo , Índias Ocidentais/etnologia , População BrancaRESUMO
It is suggested that the observed difference in duration of pregnancy between Blacks and Whites is partly physiological since it is not entirely explained by social inequities alone. This study compare women with well-defined gestational periods seeking attention at the Antoine Beclere Maternity Clinic . Group A consist of French women of European ancestry, Group B, those born in the French Antilles of mixed ancestry, and Group C Black African women with insignificant European admixture. When compared to Group A, within each socio-economic class, group B and C have shorter gestational periods. These differences persist after adjustment for socio-economic variables, so that other explanations should be considered, specifically genetic determinants.(AU)