RESUMO
The purpose of this paper is to evaluate the frequency and some of the clinical and epidemiological characteristics of asymptomatic gastric ulcer, found in persons who attend the Center for Control of Gastrointestinal Cancer of San Cristóbal, Venezuela, as part of a gastric cancer mass screening program. 350 patients with active peptic ulcer were found, 176 duodenal and 174 gastric, diagnosed by means of endoscopy. Of the patients with gastric ulcers, 67 (38.5%) had no symptoms. This group of asymptomatic patients were analyzed regarding age, sex, place of residence, type of work and also the location of the ulcer and the histology. We conclude that this entity is frequent in our region that it is associated with agricultural workers and house wives. It is necessary to continue a prospective periodical evaluation of these patients in order to understand the natural history of the entity.
Assuntos
Úlcera Gástrica/epidemiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Biópsia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Úlcera Gástrica/patologia , Venezuela/epidemiologiaRESUMO
From 1985 to 1987 we performed 82 endoscopic polipectomies in 80 patients. In this paper we refer the technics, epidemiological data and macro and microscopical findings of the resected specimens. Two patients with gastric cancer were treated in this way, these patients had formal surgical contraindication. In two patients in whom the endoscopic biopsies could not render a definitive diagnosis (cancer or atypical epithelium), the study of the resected tumor permitted the diagnosis of atypical epithelium, so two gastrectomies were avoided. Among our resected lesions we found 55 of inflammatory type, 6 adenomas and 7 atypical epithelium. We consider that this is a useful method for the diagnosis and treatment of some elevated lesions. Although this is not the treatment of choice for the elevated early cancer, it could be used to treat cancerous tumors in patients with high surgical risk.
Assuntos
Pólipos/cirurgia , Neoplasias Gástricas/cirurgia , Adulto , Idoso , Feminino , Gastroscopia , Humanos , Masculino , Pessoa de Meia-Idade , Pólipos/classificação , Pólipos/patologia , Estudos Retrospectivos , Neoplasias Gástricas/patologiaRESUMO
A multi-institutional double blind study was performed in 66 patients in order to evaluate the action of human leukocyte interferon, type alpha (IFN) in lesions produced by herpes simplex virus. Lesions were localized in genital area in 34 cases and in facial area in 32 of them. From the total, 38 patients were treated with 7,000 Ul/gm. of interferon ointment and 28 with carbowax 4,000 as placebo. The symptoms pain, ardor, itching and paresthesia were evaluated asking to patients. Erythema, vesicles, crust, scale adenopathy were objectivated. Signs and symptoms were controlled on days 3 and 7 of treatment. In 42 patients, lesions specimens were taken for virus isolation. In 23 of them, cytopathic effect was detected (54.76%). Results showed a rapid relief from pain (p less than 0.05), ardor (p less than 0.01) and paresthesia (p less than 0.001) and also accelerated healing of vesicles in patients treated with interferon. Tendency to reduce the total time of the disease in those patients treated with IFN was observed.
Assuntos
Herpes Simples/terapia , Interferon Tipo I/uso terapêutico , Administração Tópica , Adolescente , Adulto , Idoso , Argentina , Criança , Pré-Escolar , Método Duplo-Cego , Avaliação de Medicamentos , Feminino , Humanos , Lactente , Interferon Tipo I/administração & dosagem , Masculino , Pessoa de Meia-Idade , Estudos Multicêntricos como Assunto , PomadasRESUMO
Con el fin de diagnosticar cancer gastrico en su fase precoz, se realiza en el Estado Tachira un programa de despistaje masivo, el cual se lleva a cabo con unidades moviles dotadas de aparato de rayos X apropiado y donde se practican estudios radiologicos con tecnica de doble contraste a la poblacion rural comprendida por encima de los 35 anos que previamente ha sido motivada y educada por los Trabajadores Sociales. Las personas con lesiones o con sospecha de ello son sometidos a endoscopia y biopsiados. Los que resultan con cancer son sometidos a tratamiento quirurgico.Desde octubre 80 a julio 81 se han examinado 4.407 personas, diagnosticandose 58 casos de cancer gastrico de los cuales 7 han sido precoces. Tambien ha permitido diagnosticar otra patologia gastrica como: polipos, ulceras, hernias hiatales etc.suceptibles de tratamiento. Concluimos que con este metodo, el pronostico de esta enfermedad cambiara en forma muy favorable para estos pacientes y se lograra en porcentaje de sobrevida muy altos