RESUMO
Agricultural practices and industrial and human discharges play an important role in the generation of highly contaminated effluents, which becomes a threat to the environment. The persistence of many of these compounds to conventional treatments in recent years has meant that numerous efforts have been devoted to the proposal of new selective materials that allow the removal of these contaminants by adsorption. In addition, bibliometric studies have grown as powerful tools to indicate trends in innovation. In this way, the present study consisted of evaluating the potential interest to use activated carbon as adsorbent through a prospection study in scientific and technological databases. The number of records obtained for the use of activated carbon in effluent remediation processes is equivalent to 4898, which corresponds to approximately 2.5% of the total documents (articles/patents) found for the use of carbon with no defined purpose. A total of 2275 works that used the adsorptive property of activated carbon were recovered. According to the data recovered, Brazil is the leader in scientific publications among Latin American countries and the 12th worldwide, according to the SciELO and Scopus databases, respectively. In general, a significant number of patents have been recovered for this theme, in the Derwent database, 1167 documents were recovered. The results obtained in this work evidenced the growing interest in developing technologies in this area.
RESUMO
This work brings the promise of MCM-41 mesoporous silica as a vehicle for red propolis for the development of controlled release drugs and delivery to a specific target site. The synthesis of MCM-41 by the sol-gel method with a pore size of approximately 3.6 nm and the incorporation of red propolis extract by the physical adsorption method in ethanolic medium were easily accomplished with around 15% encapsulation. MCM-41 and MCM-41 with red propolis (MCM-41/Pr) were characterized by Fourier transform infrared spectroscopy, X-ray diffraction, thermal analysis, N2 adsorption-desorption, scanning electron microscopy, and an ultra-high-performance liquid chromatography-diode array detection (UPLC-DAD). In vitro release of encapsulated red propolis was analyzed in phosphate buffer at pH 7.2, 7.4, and 7.6. An in vitro test for MCM-41/Pr antioxidant activity was performed using 2,2-diphenyl-1-picrylhydrazyl as well as analysis of antibacterial activity against Staphylococcus aureus by the well diffusion method. UPLC-DAD analysis showed that the integrity of the red propolis constituents was maintained after the embed process, and the antioxidant and antibacterial activities were preserved.