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1.
Clin Nutr ESPEN ; 61: 338-348, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38777453

RESUMO

BACKGROUND & AIMS: Home Parenteral Nutrition (HPN) is the main treatment for patients with chronic intestinal failure. It is commonly prescribed for nutritional recovery, survival increase and, whenever possible, improvement of quality of life. As there are no validated instruments in Brazilian Portuguese to be used in these patients, the objective of this study was to carry out the transcultural adaptation and validation of Home Parenteral Nutrition - Quality of life (HPN-QOL©) into Brazilian Portuguese. METHODS: This observational and cross-sectional study was conducted at the multidisciplinary short-bowel syndrome clinic (AMULSIC) of the Hospital das Clínicas of the University of São Paulo Medical School (HC-FMUSP). A five-stage protocol was adopted for the transcultural adaptation: initial translation; synthesis; reverse translation; experts committee and pre-test. The adapted questionnaire was applied to a convenience (representative) sample (n = 16) and Cronbach's Alpha Coefficient, Intraclass Correlation Coefficient (ICC), and Bland-Altman Test were submitted for the analysis of the internal consistency and intraobserver and interobserver reproducibility. RESULTS: The transcultural adaptation was considered excellent (Content Validity Index = 100%). The internal consistency was satisfactory for most of the scales (16/19), and α > 0.70 was 84.21%. ICC values revealed high intraobserver and interobserver reproducibility in most of the scales. No significant difference was observed between intraobservers and interobservers in any of the questions (p > 0.05). CONCLUSIONS: The questionnaire was shown as adapted and valid for use in Brazil. Future trials with a higher sample are yet to be developed to shed light on specific scales that were inconsistent. It's expected that this would contribute for the usual quality of life assessment for individuals treated with HPN in Brazil.


Assuntos
Nutrição Parenteral no Domicílio , Qualidade de Vida , Traduções , Humanos , Brasil , Estudos Transversais , Inquéritos e Questionários , Reprodutibilidade dos Testes , Feminino , Masculino , Pessoa de Meia-Idade , Adulto , Síndrome do Intestino Curto/terapia
2.
Mol Biol Rep ; 46(3): 2851-2856, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30847848

RESUMO

Pregnancy is characterized by physiological changes. One of these changes involves calcium. During this period, an increased in calcium excretion occurs as well as an increased intestinal absorption and renal reabsorption, so that the adequate growth and development of the fetus can happen. Low calcium intake is associated with chronic diseases, such as diabetes and hypertension, which have negative impact on both mother and fetus. This study aimed to evaluate the average calcium intake of high-risk pregnant women, assisted in a clinic of high complexity service and correlated with chronic diseases. To perform this study, it was used a food frequency questionnaire. As a result, high-risk pregnant women showed daily calcium intake lower than the recommended by DRI during this period. Hypertensive or diabetic pregnant women showed lower average intake of calcium. Significant association between calcium intake and nutritional status was not observed. Calcium supplementation was present, however, at low percentage in the groups with hypertensive pregnant women. To analyze the relation between calcium intake and the comorbidities, as well as calcium intake and the nutritional status of the pregnant women, it was used one-way analysis of variance and Bonferroni multiple comparison. Further studies are required for evaluating other parameters that justify the low calcium intake among this population group, and the definition of pathways for the management of the nutritional deficit considering the possible damage to maternal and neonatal health in the short and long term.


Assuntos
Cálcio/metabolismo , Gravidez/metabolismo , Recomendações Nutricionais/tendências , Adulto , Suplementos Nutricionais , Feminino , Humanos , Educação de Pacientes como Assunto/métodos , Complicações na Gravidez , Gravidez de Alto Risco/metabolismo , Gravidez de Alto Risco/fisiologia
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