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Eur J Oral Sci ; 114(6): 489-93, 2006 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-17184230

RESUMO

Plaque fluoride concentrations ([F]) are directly related to plaque calcium concentrations [Ca]. Attempts to increase plaque F uptake from dentifrices or rinses have used methods designed to increase plaque [Ca] but with inconsistent results. This double-blind, double-crossover study tested the effect of a 150 mM calcium lactate rinse used prior to brushing with placebo or fluoridated dentifrices (1030 p.p.m. as NaF) on plaque and salivary [F] and [Ca]. Sixteen children (8-10 yr of age) were randomly assigned to four different groups according to the four treatments (placebo dentifrice or fluoridated dentifrice preceded by calcium lactate or deionized water prerinses). Plaque and saliva were collected 1 and 12 h after brushing on day 7 after starting to use the dentifrices. F was determined using the electrode and Ca was determined using atomic absorption spectrometry. Plaque and salivary [Ca] were not significantly increased after use of the calcium lactate prerinse, except for plaque [Ca] 1 h after the use of the placebo dentifrice. A significant increase in salivary [F] was associated with the calcium lactate prerinse only at 1 h after the use of the fluoridated dentifrice. The the calcium lactate prerinse did not significantly affect plaque [F] under any condition.


Assuntos
Compostos de Cálcio/farmacocinética , Cariostáticos/uso terapêutico , Placa Dentária/prevenção & controle , Dentifrícios/uso terapêutico , Lactatos/farmacocinética , Antissépticos Bucais/farmacocinética , Fluoreto de Sódio/uso terapêutico , Cálcio/análise , Criança , Estudos Cross-Over , Placa Dentária/química , Placa Dentária/metabolismo , Método Duplo-Cego , Fluoretos/análise , Humanos , Modelos Lineares , Saliva/química
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