RESUMO
OBJECTIVE: The purpose of this study was evaluate, for the first time, the impact of incorporation of nanostructured silver vanadate (ß-AgVO3) in antibiofilm and mechanical properties of dental acrylic resins (poly(methyl methacrylate), PMMA). DESIGN: The ß-AgVO3 was synthesized and characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy, and microanalysis (SEM/EDS). Resins specimens were prepared with 0-10% wt.% ß-AgVO3 and characterized by SEM, XRD and optical microscopy. The antibiofim activity of the samples against Candida albicans and Streptococcus mutans was investigated by XTT reduction test, colony-forming units (CFUs), and confocal laser scanning microscopy (CLSM). The flexural strength, hardness, and surface roughness of the samples containing ß-AgVO3 were compared with the pure PMMA matrix. RESULTS: The incorporation of 10% ß-AgVO3 significantly reduced the metabolic activity of C. albicans and S. mutans (p<0.05). There was a reduction in microbial load (CFU/mL) of microorganisms for the different concentrations used (p<0.05), which was confirmed by confocal microscopy. The addition of ß-AgVO3 did not change the mechanical properties of hardness and surface roughness of the resins (p>0.05). However, flexural strength decreased with the addition of amounts greater than 1% (p<0.05). CONCLUSIONS: ß-AgVO3 additions in dental acrylic resin may have an impact on inhibition of biofilm of main microorganisms associated with dental prostheses. However, the viability of clinical use should be evaluated in function of changed promoted in some mechanical properties.
Assuntos
Resinas Acrílicas/farmacologia , Biofilmes/efeitos dos fármacos , Nanocompostos/química , Prata/farmacologia , Vanadatos/farmacologia , Resinas Acrílicas/síntese química , Resinas Acrílicas/química , Candida albicans/efeitos dos fármacos , Candida albicans/crescimento & desenvolvimento , Resinas Compostas/química , Materiais Dentários/química , Dureza , Teste de Materiais , Polimetil Metacrilato/química , Polimetil Metacrilato/farmacologia , Prata/química , Streptococcus mutans/efeitos dos fármacos , Streptococcus mutans/crescimento & desenvolvimento , Vanadatos/químicaRESUMO
BACKGROUND: Knowledge of benefits caused by a treatment on quality of life is very relevant. Despite the wide use and acceptance of soft denture liners, it is necessary to evaluate the patient's response about the use of these materials with regard to improvement in oral health related quality of life (OHRQoL). OBJECTIVES: The aim of this study was to evaluate the influence of denture relining in the OHRQoL of edentulous patients. MATERIALS AND METHODS: Thirty-two complete denture wearers had their lower dentures relined with a silicone-based material (Mucopren soft, Kettenbach, Germany) according to chairside procedures. OHRQoL was assessed before and after 3 months of relining by means of OHIP-EDENT, and the median scores were compared by Wilcoxon test (p ≤ 0.05). RESULTS: After 3 months of relining, participants reported significant improvement of their OHRQoL (p ≤ 0.01). CONCLUSION: Denture relining with a soft liner may have a positive impact on the perceived oral health of edentulous patients.