RESUMO
Organophosphate esters (OPEs) used as flame retardants and plasticizers are additives in building and construction materials, decorations, furniture, electronic equipment, among other applications. The presence of materials containing these substances in construction and demolition waste (CDW) from weak waste management practices can result in environmental contamination. In this study, OPEs' presence in soil samples collected from a CDW landfill in Brazil was evaluated. Soil samples were collected in areas adjacent to CDW from an inert landfill, and the samples were analysed by gas chromatography coupled to mass spectrometry. The OPEs were detected in all soil samples at quantifiable concentrations ranging from 21 to 251 ng g-1, and detected compounds were tris(phenyl) phosphate, tris(2-butoxyethyl) phosphate, tris(1,3-dichloroisopropyl) phosphate, tris(2-chloroisopropyl) phosphate and 2-ethylhexyl diphenyl phosphate. The presence of these compounds in a CDW landfill is probably due to the lack of control of the materials sent to and deposited in the landfill, which, results in part from the lack of sampling and screening systems that can help identify the presence of contaminants in the CDW waste stream. This is partially due to OPEs not being considered controlled compounds under current regulations, thus screening or separation for handling of OPEs at construction and demolition work sites is rare to non-existent. The data generated in this study reveals the need for improving CDW management to minimize, if not eliminate, environmental contamination by OPEs.
RESUMO
Since the creation of the Brazilian Headache Society in 1978, substantial developments have taken place in both research and clinical practice in the field of headache medicine in Brazil. The Society now has almost 300 members throughout the country, actively working to improve the health of the general population and, in particular, diagnose and treat headache disorders. In addition, in a few large cities, such as São Paulo, Rio de Janeiro, Recife, Ribeirão Preto, Curitiba, and Porto Alegre, headache specialists have come together to promote research projects and increase knowledge in the field through MSc, PhD, and postdoctoral programs. Furthermore, scientific journals have emerged and books have been published to record and disseminate Brazilian scientific production in headache medicine. In this narrative review, we will briefly describe some important aspects of headache medicine in Brazil from prehistoric times to the present day, discuss the origin of headache medicine as a specialty in Brazil, the principal publications dealing with headache disorders, the use of plants and other unconventional forms of treatment used by faith healers, the main training centers, and the research produced to date by Brazilians. In conclusion, in recent years enormous progress has been made in headache medicine in Brazil stimulating us to review and expand our role in an increasingly international scenario.