1.
Bioorg Med Chem
; 13(1): 193-6, 2005 Jan 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15582464
RESUMO
A series of new amino derivatives and a new partially hydrogenated derivative of the natural naphthoquinone lapachol were assayed for molluscicidal activity against Biomphalaria glabrata. These derivatives showed low to medium LC(50) values, and a 3.1 microg/mL value for the most potent derivative of the series. The toxicity is in agreement with the decrease of polar character of the tested compounds.