RESUMO
ABSTRACT Background: Obesity is a worldwide challenging health problem. Weight loss through medical management of obesity has not always been successful, thus, giving rise to the need for surgical intervention. Bariatric surgery has been shown to be helpful for morbidly obese patients. However, studies have also shown the effect of surgery on stone formation, fertility and erectile function. This review summarizes the main findings of several studies that analyze stone formation and fertility in men as well as erectile function post bariatric surgery. The underlying pathophysiologic alterations post bariatric surgery include increased absorption of oxalate leading to hyperoxaluria, hypocitraturia and increased urinary calcium oxalate supersaturation. Contradicting data exist on the effect of bariatric surgery on fertility and erectile function. Further studies are needed to analyze the mechanisms.
Assuntos
Humanos , Masculino , Ereção Peniana/fisiologia , Cálculos Renais/etiologia , Cirurgia Bariátrica/efeitos adversos , Infertilidade Masculina/etiologia , Complicações Pós-Operatórias/fisiopatologia , Oxalato de Cálcio/metabolismo , Derivação Gástrica/efeitos adversos , Cálculos Renais/fisiopatologia , Fatores de Risco , Disfunção Erétil/fisiopatologia , Infertilidade Masculina/fisiopatologia , Obesidade/complicações , Obesidade/fisiopatologia , Obesidade/terapiaRESUMO
BACKGROUND: Obesity is a worldwide challenging health problem. Weight loss through medical management of obesity has not always been successful, thus, giving rise to the need for surgical intervention. Bariatric surgery has been shown to be helpful for morbidly obese patients. However, studies have also shown the effect of surgery on stone formation, fertility and erectile function. This review summarizes the main findings of several studies that analyze stone formation and fertility in men as well as erectile function post bariatric surgery. The underlying pathophysiologic alterations post bariatric surgery include increased absorption of oxalate leading to hyperoxaluria, hypocitraturia and increased urinary calcium oxalate supersaturation. Contradicting data exist on the effect of bariatric surgery on fertility and erectile function. Further studies are needed to analyze the mechanisms.