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Gac Med Mex ; 136(3): 193-9, 2000.
Artigo em Espanhol | MEDLINE | ID: mdl-10893847

RESUMO

BACKGROUND: Prevalence Candida infections have increased and oncologic patients have risk factors for contacting them. They are associated with a long hospital stay and high mortality rate. Candida resistance to antifungal drugs has been reported. OBJECTIVES: To determine the prevalence of Candida grown in cultures from oncologic patients. To identify isolated species and to determine C albicans sensitivity to antifungal drugs. MATERIAL AND METHODS: During one year, different species of Candida spp. were isolated. They were inoculated in API-C-20 at 48 h. and cultivated in RPMI-1640. RESULTS: Cultures of 5,820 patients were collected, 66.68% from outpatients and 33% from hospitalized patients. Candida spp grew in 394 Candida albicans obtained from 81 cultures was the most frequent species (46.3%). One hundred were susceptible to Amphotericin B, 63% to Fluconazol, 59% to Ketoconazol and 31% to Itraconazol. Candidemia accounted for 24.6% of bloodstream infections. CONCLUSIONS: C. albicans had significant resistance to imidazoles and 100% were susceptible to Amphotericin B. Identification of species and susceptibility of Candida infections a useful tools because of the high proportion of Candida non-albicans species (53.7%). Candidemia accounted for 5.076% of the infections.


Assuntos
Antifúngicos/farmacologia , Candida albicans/efeitos dos fármacos , Candidíase/epidemiologia , Hospitais Especializados , Humanos , Testes de Sensibilidade Microbiana , Prevalência
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