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BACKGROUND: Breast cancer is a prevalent form of cancer among women worldwide, often accompanied by physical and psychological side effects due to the disease and the treatment's aggressiveness. Regular physical exercise has emerged as a non-pharmacological approach to improve the quality of life of breast cancer survivors. We herein report the protocol of the WaterMama Study, which aims to evaluate the effects of land- or water-based aerobic exercise programs, compared to a health education program, on cancer-related fatigue and other health-related outcomes in breast cancer survivors. METHODS: The WaterMama trial is a randomized, single-blinded, three-arm, parallel, superiority trial. We aim to recruit 48 women ≥ 18 years of age who have completed primary treatment for stage I-III breast cancer. Participants are randomly allocated in a 1:1:1 ratio to 12-week interventions of aerobic exercise training programs either in the aquatic or land environment (two weekly 45-min sessions) plus health education (a weekly 45-min session), or an active-control group receiving health education alone (a weekly 45-min session). The primary outcome is cancer-related fatigue, and the secondary outcomes include cardiorespiratory fitness, muscular performance, muscle morphology, functional capacity, mental health, cognitive function, pain, and quality of life. Outcomes assessments are conducted before and after the 12-week intervention period. The analysis plan will employ an intention-to-treat approach and per protocol criteria. DISCUSSION: Our conceptual hypothesis is that both aerobic exercise programs will positively impact primary and secondary outcomes compared to the health education group alone. Additionally, due to its multi-component nature, we expect the aquatic exercise program promote more significant effects than the land exercise program on cancer-related fatigue, muscular outcomes, and pain. TRIAL REGISTRATION: The study was prospectively registered at ClinicalTrials.gov NCT05520515. Registered on August 26, 2022. https://clinicaltrials.gov/ct2/show/NCT05520515.

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Resumo O objetivo do presente estudo foi avaliar e testar a correlação entre força isométrica de preensão manual (FIPM), nível de atividade física (AF) e qualidade de vida (QV) de competidores máster de judô. A amostra foi composta por 44 homens (45 a 64 anos), participantes do Campeonato Panamericano Master de Judô de 2011. Para avaliar a força manual, utilizou-se teste de força isométrica de preensão manual. Empregaram-se os questionários WHOQOL-Breve e Questionário de Atividade Física Global (GPAQ). Na análise estatística, após a verificação da normalidade na distribuição dos dados, os mesmos são apresentados com média [Intervalo de confiança 95%]. Na comparação entre grupos etários, foi conduzida análise de variância (ANOVA), com pos-hoc de Tukey. Para correlações bivariadas, empregou-se o teste de Pearson. Os competidores de judô demonstraram: 1) quantidade elevada de AF (661 [513-810] min de AF moderada a vigorosa) quando se consideram as recomendações populacionais; 2) FIPM com valores moderados (soma bilateral de 87,1 [82,3-91,9] kgf) comparados com pessoas fisicamente ativas e idosos; e 3) escores de QV superiores aos registrados em outros estudos. Adicionalmente, destacam-se dois principais achados, ausência de diferenças significantes para percepção subjetiva de QV e de FIPM segundo grupos etários e correlação positiva entre quantidade semanal de AF moderada a vigorosa e escores de QV.(AU)

Abstract The aim of this study was to evaluate and test the correlation between isometric handgrip (IH), physical activity level (PA) and quality of life (QOL) of master judo competitors. The sample was composed by 44 men (45-64 years) participating in the Pan-American Master Judo Championships, 2011. To evaluate the handgrip strength was used isometric handgrip test. Additionally, were employed WHOQOL-Bref questionnaire and Global Physical Activity Questionnaire (GPAQ). In the statistical analysis, after checking the normal distribution of the data, they are presented as mean [95% confidence interval]. In the comparison between age groups, we conducted analysis of variance (ANOVA) with Tukey post-hoc. For bivariate correlations, we used the Pearson test. The judo athletes showed: 1) high amount of PA (661 [513-810] min of moderate to vigorous PA) when considering the population recommendations; 2) moderate values of FIPM (bilateral sum equal to 87.1 [82.3 -91.9] kgf) compared with physically active people and the elderly; and 3) QOL scores higher than in other studies. Additionally, we highlight two main findings, no significant differences in subjective perception of QOL and FIPM by age groups and positive correlation between weekly amount of moderate to vigorous PA and QoL scores.(AU)

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