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3.
s.l; s.n; dec. 1984. 2 p.
Não convencional em Inglês | Sec. Est. Saúde SP, HANSEN, Hanseníase, SESSP-ILSLACERVO, Sec. Est. Saúde SP | ID: biblio-1240913

RESUMO

Light chain proteinuria is a recognised cause of renal disease and renal failure. In 1973 Graber et al described light chain proteinuria occuring in patients given rifampicin and there have since been two case reports of renal failure due to rifampicin induced light chain proteinuria.


Assuntos
Masculino , Humanos , Pessoa de Meia-Idade , Cadeias Leves de Imunoglobulina/urina , Desidratação/complicações , Injúria Renal Aguda/induzido quimicamente , Proteinúria/induzido quimicamente , Rifampina/efeitos adversos
6.
J Pediatr ; 93(2): 299-303, 1978 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-671172

RESUMO

Plasma prednisolone levels have been measured hourly in children receiving a single dose of oral prednisone. Peak prednisolone levels occurred one to two hours after ingestion; half-life studies gave a mean value of 132 minutes in most children. Some children had marked variability in absorption and metabolism of prednisone. Somatomedin activity and cell-mediated immunity were inhibited by plasma prednisolone values which were achieved by single doses of prednisone of 0.5 mg/kg or higher. Monitoring prednisolone levels may be of value in identifying those children who accumulate excessively high levels on moderate dosage regimens.


Assuntos
Prednisolona/sangue , Administração Oral , Adolescente , Hiperfunção Adrenocortical/tratamento farmacológico , Asma/tratamento farmacológico , Disponibilidade Biológica , Criança , Pré-Escolar , Doença de Crohn/tratamento farmacológico , Dermatomiosite/tratamento farmacológico , Feminino , Meia-Vida , Humanos , Imunidade Celular/efeitos dos fármacos , Lúpus Eritematoso Sistêmico/tratamento farmacológico , Masculino , Síndrome Nefrótica/tratamento farmacológico , Prednisolona/administração & dosagem , Prednisolona/metabolismo , Prednisolona/uso terapêutico , Somatomedinas/sangue
7.
J Pediatr ; 89(3): 401-5, 1976 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-989056

RESUMO

Twenty-one patients were seen with the diagnosis of chronic lymphocytic thyroiditis in the Endocrine Clinic during 1965-1972. Three patients developed clinical diabetes mellitus at intervals from one month to three years after the diagnosis of thyroiditis was confirmed. An additional patient, a member of the study group reported here, had asymptomatic glucose intolerance initially and developed insulin-dependent diabetes mellitus six months after the diagnosis of thyroiditis was established. Standard glucose tolerance tests were performed on 12 additional patients. One of these patients had unequivocal evidence of chemical diabetes; one other had a borderline abnormal oral glucose tolerance test. The remaining ten patients had normal glucose and insulin values during the OGTT. These studies indicate that children with chronic lymphocytic thyroiditis are at increased risk of developing diabetes mellitus when compared with the normal childhood population.


Assuntos
Diabetes Mellitus/epidemiologia , Tireoidite Autoimune/complicações , Glicemia/análise , Criança , Doença Crônica , Diabetes Mellitus/sangue , Teste de Tolerância a Glucose , Humanos , Illinois , Risco , Tireoidite Autoimune/sangue
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