RESUMO
We conducted a retrospective study of neonatal leukocytosis induced by prostaglandin E(1). Among 45 neonates with congenital heart disease, leukocyte counts increased during PGE(1) infusion. We conclude that PGE(1) infusion is a predictable cause of leukocytosis in newborns with congenital heart disease.
Assuntos
Alprostadil/efeitos adversos , Leucocitose/induzido quimicamente , Feminino , Cardiopatias Congênitas/dietoterapia , Humanos , Recém-Nascido , Contagem de Leucócitos , Estudos RetrospectivosRESUMO
PIP: The author analyzes the conflict inherent in current American attitudes toward immigration, in which a general desire to control and limit immigration, particularly from Mexico, contrasts with a general willingness to profit from such immigration as a source of cheap and available labor. Particular attention is given to the situation in California and to the debate surrounding Proposition 187. The author suggests that the main concerns of Americans about immigration are with issues of race and security, and the conflict between the ideals of working toward a more democratic society and building more controls to create a more secure society.^ieng
Assuntos
Atitude , Emigração e Imigração , Política Pública , Relações Raciais , Controle Social Formal , América , Comportamento , California , Demografia , Países Desenvolvidos , Países em Desenvolvimento , América Latina , México , América do Norte , Política , População , Dinâmica Populacional , Psicologia , Estados UnidosRESUMO
This study reports on a prospective Adverse Drug Reaction (ADR) surveillance programme at the Queen Elizabeth Hospital, Barbados, from September 1989 to November, 1992. ADR forms were prominantly displayed in each ward of the Queen Elizabeth Hospital and completed forms were collected by Hospital Pharmacy staff. Data were analysed in terms of frequency of ADRs with reference to age, gender, therapeutic category, the monthly variation in reporting according to department and medical team. A total of 145 reports were considered complete and valid. Antidiabetic agents were implicated in 35 per cent of all reports, while the most commonly reported ADR was hypoglycaemia (32 per cent). The frequency of ADRs was uniform over the age range 10 - 60 years, but increased greatly in patients over 60 years of age. Frequency of reports was dependent on intensity of education and lobbying of doctors to report, and fell sharply when two key team members left the hospital. This study, the first known report of ADR surveillance in the Caribbean, clearly demonstrates that adverse drug reactions contribute significantly to morbidity in our elderly population, as in other reports. Reporting is subject to many variables and is clearly incomplete, but it is an important aspect of total patient care and drug use review. It highlights the risks of some drugs (e.g. sulphonylureas, sulphonamides, potassium sparing diuretics) which may be carelessly used, as well as rare ADRs (AU)