RESUMO
Five tamarins (four Saguinus mystax and one S. labiatus) died with wasting syndrome characterized by chronic diarrhea at the Center for Reproduction and Conservation of Non-Human Primates in Iquitos, Peru. At necropsy, the terminal ileum of all affected tamarins was found to be markedly thickened. Histologically, the terminal ileal mucosa was completely ulcerated, and effaced by debris and mononuclear inflammatory cells. The submucosa and serosa were thickened by fibroplasia, mononuclear cell infiltrates and variable edema. No infectious agent was observed. The lesions were similar to those described previously for Crohn disease. This is to our knowledge the first report of terminal ileitis resembling Crohn disease in non-human primates.
Assuntos
Doença de Crohn/patologia , Doença de Crohn/veterinária , Doenças dos Macacos/patologia , Saguinus , Animais , Doença de Crohn/diagnóstico , Feminino , Histologia , Mucosa Intestinal/patologia , Obstrução Intestinal/patologia , Masculino , Doenças dos Macacos/diagnósticoRESUMO
Serum and urine analytes were compared between adult wild-caught owl monkeys (Aotus nancymae) and adult wild-caught squirrel monkeys (Saimiri peruviensis) to determine if normative clinical pathology data were similar. An objective of the study was to confirm that species of neotropical primates are distinct with regard to physiologic parameters, and should not be considered interchangeable in biomedical research. Significant differences (P < 0.05) were noted in many serum and urine analytes between the two groups. The results suggest that reference data for wild-caught owl monkeys are not applicable to squirrel monkeys, and the differences are sufficiently large to be of clinical significance. These findings illuminate the diversity among species of neotropical primates.
Assuntos
Aotus trivirgatus/sangue , Saimiri/sangue , Animais , Animais Selvagens , Aotus trivirgatus/urina , Análise Química do Sangue/veterinária , Proteínas Sanguíneas/análise , Eletrólitos/sangue , Eletrólitos/urina , Peru , Proteinúria , Saimiri/urina , Especificidade da Espécie , Manejo de Espécimes/instrumentação , Manejo de Espécimes/métodos , Manejo de Espécimes/veterinária , Urinálise/veterináriaRESUMO
Blood samples from 35 wild-caught owl monkeys (Aotus vociferans, karyotype V) were analyzed to estimate reference intervals of hematologic variables for the species. Findings indicated that distributions were abnormal for leukocytes, neutrophils, eosinophils, basophils, and monocytes. Statistically significant sex differences, too small to be of clinical importance, were found in values for mean cell hemoglobin concentration, leukocytes, and basophils. Reference intervals for the hematologic variables were calculated by the nonparametric percentile estimation method. Comparison of hematologic reference values for wild-caught A. vociferans with those of A. nancymae revealed statistically significant differences for packed cell volume, mean cell volume, leukocytes, eosinophils, basophils, and platelets. These differences also appeared too small to be of clinical significance.
Assuntos
Aotidae/sangue , Contagem de Células Sanguíneas/veterinária , Índices de Eritrócitos/veterinária , Hemoglobinas/análise , Animais , Aotidae/genética , Contagem de Eritrócitos/veterinária , Feminino , Cariotipagem/veterinária , Contagem de Leucócitos/veterinária , Masculino , Contagem de Plaquetas/veterinária , Valores de Referência , Caracteres SexuaisAssuntos
Custos de Cuidados de Saúde/tendências , Ciência de Laboratório Médico/tendências , Análise Custo-Benefício , Sistemas Pré-Pagos de Saúde/economia , Prioridades em Saúde/economia , Prioridades em Saúde/tendências , Seguro Saúde/economia , Marketing de Serviços de Saúde/economia , Marketing de Serviços de Saúde/tendências , Ciência de Laboratório Médico/economia , Transferência de Tecnologia , Estados UnidosRESUMO
Of the 232 tamarins (133 Saguinus mystax and 99 Saguinus labiatus) that died at the Center for Reproduction and Conservation of Nonhuman Primates in Iquitos, Peru from January 1987 to December 1990, 23 monkeys (9.9%) were diagnosed as having chronic colitis. Typically, the cecal and colonic mucosa was greyish and small yellowish cysts, measuring 1-4 mm, were found randomly distributed bulging the mucosa. Microscopically, colitis cystica profunda was diagnosed additionally in six more animals, giving a total of 29 cases (12.5%). This is the first report to our knowledge that describes colitis cystica profunda in a nonhuman primate.
Assuntos
Colite/veterinária , Mucosa Intestinal/patologia , Doenças dos Primatas , Saguinus , Animais , Ceco/patologia , Colite/patologia , Colo/patologia , Feminino , Masculino , PeruRESUMO
A wild-caught adult female Saguinus mystax died after 54 months in captivity. At necropsy, a small reddish zone in the renal cortex of one kidney was shown histologically to be a hemangiosarcoma.
Assuntos
Hemangiossarcoma/veterinária , Neoplasias Renais/veterinária , Doenças dos Macacos/patologia , Saguinus , Animais , Feminino , Hemangiossarcoma/patologia , Neoplasias Renais/patologiaRESUMO
A wild-caught male Aotus vociferans died spontaneously during quarantine. Histologic examination of the heart showed several small myocardial arteries replaced with fibrinoid necrosis and adjacent inflammation that included lymphocytes and large histiocytic cells. Less often, similar inflammatory foci were observed in the myocardium interstitium. The lesions observed in the heart of the owl monkey resembled Aschoff bodies.
Assuntos
Aotidae , Cardiomiopatias/veterinária , Doenças dos Macacos/patologia , Cardiopatia Reumática/veterinária , Doença Aguda , Animais , Animais Selvagens , Cardiomiopatias/patologia , Masculino , Cardiopatia Reumática/patologia , Infecções Estreptocócicas/patologia , Infecções Estreptocócicas/veterináriaRESUMO
Clinical and pathologic data were reviewed for 72 owl monkeys that died between January 1987 and May 1990 at the Center for Reproduction and Conservation of Nonhuman Primates in Iquitos, Peru. Tissue samples from 39 animals were examined. Hypertrophic cardiac disease (51% of animals examined), dilative cardiomyopathy (26%), and nephropathy (87%) were the most common diagnoses. The incidence of all three diseases appeared to increase with time in captivity. Nephropathy was less severe in colony-born animals.
Assuntos
Aotidae , Cardiomiopatias/veterinária , Nefropatias/veterinária , Doenças dos Macacos/patologia , Animais , Cardiomiopatias/patologia , Feminino , Nefropatias/patologia , MasculinoRESUMO
Impaired renal function was observed in sixteen Aotus nancymai 25 and 3 months following infection with the Uganda Palo Alto strain of Plasmodium falciparum. Decrease were noted in the clearance of endogenous creatinine, creatinine excretion, and urine volume while increases were observed in serum urea nitrogen, urine protein, urine potassium, fractional excretion of phosphorus and potassium, and activities of urinary enzymes. The results were suggestive of glomerulonephropathy and chronic renal disease.
Assuntos
Aotus trivirgatus/parasitologia , Rim/fisiopatologia , Malária Falciparum/fisiopatologia , Animais , Sangue/parasitologia , Creatinina/metabolismo , Eletrólitos/metabolismo , Enzimas/urina , Feminino , Taxa de Filtração Glomerular , Glomerulonefrite Membranoproliferativa/etiologia , Glomerulonefrite Membranoproliferativa/urina , Testes de Função Renal , Malária Falciparum/complicações , Malária Falciparum/metabolismo , Malária Falciparum/parasitologia , Masculino , Nitrogênio/metabolismo , Proteinúria/etiologia , Proteinúria/urinaRESUMO
Impaired renal function was observed in sixteen Aotus nancymai 25 and 3 months following infection with the Uganda Palo Alto strain of Plasmodium falciparum. Decrease were noted in the clearance of endogenous creatinine, creatinine excretion, and urine volume while increases were observed in serum urea nitrogen, urine protein, urine potassium, fractional excretion of phosphorus and potassium, and activities of urinary enzymes. The results were suggestive of glomerulonephropathy and chronic renal disease
Assuntos
Animais , Cebidae , Rim/patologia , Plasmodium falciparumRESUMO
Four hundred and fifty wild-caught owl monkeys (Aotus nancymai) were shipped from Iquitos, Peru to Richland, Washington. Mortality and body weight changes from the time of shipment to 30 days after arrival were evaluated using age, sex, and transit time as comparison criteria. No association between mortality and sex, age, or transit time was observed. The mortality percentage from shipment to 30 days after arrival was 2.44%. Both age and transit time had a significant effect on weight changes, but sex did not. Shipping procedures are described.