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5.
Bol Med Hosp Infant Mex ; 37(3): 483-97, 1980.
Artigo em Espanhol | MEDLINE | ID: mdl-6772198

RESUMO

This study was conducted at the National Children's Hospital, in Costa Rica. Fifteen malnourished children (means upon admission: age 7.5 months; 55.2% weight for age; 74.3 weight for height) were treated according to a new feeding scheme in which hypercaloric formulas were given to children from the seventh day onwards. The children achieved a mean weight gain of 8.7 g/kg/day after the first week of hospitalization. A strong correlation was found between caloric intake and weight gain (r = 0.78). The equation Y = -10.36 + 0.1X indicates and additional caloric requirement of 10 Kcal/kg/day for synthesis of tissue of 1 g/kg/day. Children achieved an average of 90% weight/height four weeks after initiation of treatment, advancing from grade III to grade II (weight deficit, Gómez classification) The application of this feeding scheme will reduce hospitalization cost, the risk of cross-infections, the rate of readmissions, and will favor a better adaptation of the child to his own environment.


Assuntos
Desnutrição Proteico-Calórica/dietoterapia , Peso Corporal , Costa Rica , Feminino , Humanos , Masculino
6.
Am J Clin Nutr ; 29(10): 1073-88, 1976 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-823814

RESUMO

This report presents an account of energy balance of young Jamaican children recovering from protein-energy malnutrition (PEM). This was done in three steps. Initially the true gross energy of a formula used in the treatment of PEM was determined by bomb calorimetry. Then its metabolizable energy content was determined in a group of nine children recovering from PEM. In a similar but different group of eight children total daily metabolizable energy intake (EI), average rate of weight gain (g/kg/day) (WG), and total daily energy expenditure (TDEE) were determined. TDEE was determined by indirect calorimetry using a heart rate counter and is based on the relationship of heart rate to oxygen consumption. In this group, the mean EI was 122.5 kcal, WG was 8.4 g, and TDEE was 92 kcal. The difference between EI and TDEE was 30.7 kcal/kg, or 3.3 kcal/g of weight gain. This difference is presumed to be the stored energy in new tissue and corresponds to a proposed new tissue composition of 31% fat and 14% protein. A regression curve comparison of WG versus EI showed that at zero weight gain EI was 85.5 kcal and each additional gain. The difference of 1.0 kcal between total energy cost and stored energy reflects the energy required to deposit new tissue. Gram weight gain required 4.4 kcal. The latter figure is felt to reflect the total energy cost of weight. From three independent measurements, an estimate of maintenance energy requirements was estimated to be about 82 kcal/kg/day.


Assuntos
Metabolismo Energético , Desnutrição Proteico-Calórica , Calorimetria , Calorimetria Indireta , Pré-Escolar , Convalescença , Fezes , Feminino , Crescimento , Frequência Cardíaca , Humanos , Lactente , Alimentos Infantis , Jamaica , Kwashiorkor , Masculino , Necessidades Nutricionais , Desnutrição Proteico-Calórica/dietoterapia , Desnutrição Proteico-Calórica/metabolismo , Magreza
7.
Am J Clin Nutr ; 28(11): 1330-6, 1975 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-1190111

RESUMO

The fat content of the liver has been measured in 163 biopsy specimens taken from 95 malnourished children in Jamaica within a few days of admission to hospital and at various stages of recovery. The fat content was also measured in 38 samples from children who died. Severe degrees of fatty infiltration, up to 50% of the wet weight, were found. Fatty liver of this degree of severity may be a cause of death. The increase in fat was accompanied by an increase in water content. This may be the result of breakdown in the energy-dependent regulation of water content. Repeat biopsies were done within 6 weeks of admission in 26 children. The average rate of clearance of fat expressed as a fraction of the amount present at any time was 5.5% per day. An attempt was made by more frequent biopsies to determine whether the rate of decrease was influenced by the protein content of the diet, but the results were inconclusive.


Assuntos
Transtornos da Nutrição do Lactente/metabolismo , Metabolismo dos Lipídeos , Fígado/metabolismo , Água Corporal/metabolismo , Pré-Escolar , Proteínas Alimentares/uso terapêutico , Fígado Gorduroso/etiologia , Fígado Gorduroso/mortalidade , Humanos , Lactente , Transtornos da Nutrição do Lactente/dietoterapia , Transtornos da Nutrição do Lactente/mortalidade , Jamaica
13.
Biochem J ; 113(2): 2P-3P, 1969 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-16742668
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