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Radiat Prot Dosimetry ; 127(1-4): 223-6, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17569685

RESUMO

Absorbed fraction (AF) calculations to the human skeletal tissues due to alpha particles are of interest to the internal dosimetry of occupationally exposed workers and members of the public. The transport of alpha particles through the skeletal tissue is complicated by the detailed and complex microscopic histology of the skeleton. In this study, both Monte Carlo and chord-based techniques were applied to the transport of alpha particles through 3-D microCT images of the skeletal microstructure of trabecular spongiosa. The Monte Carlo program used was 'Visual Monte Carlo--VMC'. VMC simulates the emission of the alpha particles and their subsequent energy deposition track. The second method applied to alpha transport is the chord-based technique, which randomly generates chord lengths across bone trabeculae and the marrow cavities via alternate and uniform sampling of their cumulative density functions. This paper compares the AF of energy to two radiosensitive skeletal tissues, active marrow and shallow active marrow, obtained with these two techniques.


Assuntos
Osso e Ossos/fisiologia , Modelos Biológicos , Contagem Corporal Total/métodos , Partículas alfa , Bioensaio/métodos , Simulação por Computador , Humanos , Internacionalidade , Cinética , Método de Monte Carlo , Especificidade de Órgãos , Doses de Radiação , Eficiência Biológica Relativa , Sensibilidade e Especificidade , Especificidade da Espécie , Distribuição Tecidual
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