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1.
Photobiomodul Photomed Laser Surg ; 42(6): 422-427, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38717840

RESUMO

Objective: To present a case report of maxillary lateral incisor root regeneration after severe root resorption, treated with photobiomodulation (PBM). Background: Impacted maxillary canines often come with the risk of maxillary lateral incisor root resorption, which is widely recognized as the predominant adverse effect in these situations. This progressive process of root resorption is currently irreversible, with no known way to reverse it. Materials and methods: A male patient was 14 years old. Radiographically it was observed that canine 23 is impacting against the root of 22 producing signs of root resorption and having a less than 1:1 crown-to-root ratio with mobility grade 1. From the beginning of the treatment, PBM-assisted orthodontics was proposed. To address the patient's dental concerns, the treatment plan outlined the extraction of the deciduous upper left canine tooth leaving the lateral as long as possible in the mouth. During each appointment, PBM was applied with a diode laser. The wavelength was 810 nm, Ap = 0.2 W, 4.4 J, 22 sec every 21 days, 13 applications in total (57.2J), with a 400 µm inactive surgical tip, in a scanning movement, 1 mm from the mucosa while moving following the vestibular surface of the upper left lateral and canine roots. Results: After 12 months, the 22 had root neoformation and complete closure of the apex with vitality. Conclusions: PBM with an 810 nm diode laser in this clinical case promoted root regeneration of an upper lateral incisor, with severe root resorption, owing to an impacted maxillary canine while still vital.


Assuntos
Dente Canino , Incisivo , Terapia com Luz de Baixa Intensidade , Reabsorção da Raiz , Dente Impactado , Humanos , Masculino , Reabsorção da Raiz/etiologia , Adolescente , Regeneração/efeitos da radiação , Maxila , Raiz Dentária/efeitos da radiação , Lasers Semicondutores/uso terapêutico
4.
Rev. colomb. radiol ; 27(3): 4537-4539, 2016. ilus
Artigo em Espanhol | LILACS, COLNAL | ID: biblio-987205

RESUMO

El hematoma intramural aórtico (HIM) forma parte del espectro del síndrome aórtico agudo. En el HIM se pueden presentar colecciones de medio de contraste conocidas en la literatura como "pool sanguíneo intramural" (PSIM) y "proyección similar a una úlcera" (PSU). El PSIM puede estar comunicado con ramas de la aorta o con la luz de la misma por un orificio intimal pequeño (1-2 mm). La PSU presenta una solución de continuidad intimal mayor de 3 mm de diámetro y, a diferencia de la úlcera aterosclerótica penetrante, no se acompaña de una placa ateroesclerótica. En general, la presencia de PSIM en pacientes con HIM aórtico no se asocia a mal pronóstico. Se presenta el caso de una paciente con dolor torácico y sospecha de disección aórtica, estudiada en nuestra institución con angiografía por tomografía computada, que demostró HIM y una colección de medio de contraste en el espesor del hematoma, interpretada como pool sanguíneo intramural. Se revisan las imágenes iniciales y el control con endoprótesis aórtica.


Aortic intramural hematoma (IMH) is part of the spectrum of acute aortic syndromes. Collections of contrast medium known in the literature as "intramural blood pool" (IMBP) and "ulcer-like projections" (ULP), may be present in the IMH. An IMBP could be connected with branches of the aorta or with the aortic lumen through a small tear in the intima (1-2 mm). The ULP represents a disruption of the intima greater than 3mm of diameter and unlike the penetrating atherosclerotic ulcer, this is not associated with an atherosclerotic plaque. In general, the presence of IMBP in patients with aortic IMH is not associated with poor prognosis. We present a case of a patient with chest pain and suspected aortic dissection, studied at our institution with CT angiography, which showed an IMH and a collection of contrast medium within the thickness of the hematoma, interpreted as an intramural blood pool. The initial images and control with aortic endograft are reviewed.


Assuntos
Humanos , Doenças da Aorta , Aorta Torácica , Ruptura Aórtica
5.
Acta méd. colomb ; 40(4): 353-353, oct.-dic. 2015. ilus, tab
Artigo em Espanhol | LILACS, COLNAL | ID: biblio-949488

RESUMO

Paciente masculino de 52 años con dolor torácico de características pleuríticas y disnea de cuatro meses de evolución. La radiografía (imagen IA) y la tomografía computarizada (TC) de tórax (Figura IB), mostraron engrosamiento nodular difuso de la pleura y efusión pleural. El engrosamiento pleural se define por un espesor de la pleura > de 3 mm que puede ser focal o difuso. En la radiografía frontal se considera un engrosamiento pleural difuso a la alteración mayor de 25% de la superficie pleural (bilateral) o mayor de 50% (unilateral). En TC se puede considerar difuso al engrosamiento pleural con una longitud > 8 cm y un diámetro mayor de 5 cm . El engrosamiento del paciente: difuso, concéntrico y nodular sugiere enfermedad neoplásica (primaria o secundaria), principalmente: enfermedad metastásica, mesotelioma, linfoma y timoma invasivo. Ocasionalmente entidades infecciosas pueden presentar este hallazgo. La patología pleural del paciente confirmó mesotelioma maligno epitelioide. Este mesotelioma es más frecuente en personas entre la sexta y séptima década de la vida, predomina en hombres y se asocian a la exposición a asbestos.


Assuntos
Masculino , Pessoa de Meia-Idade , Pleura , Tomografia Computadorizada por Raios X , Doença , Dispneia
7.
Med. lab ; 2014, 20(1-2): 87-92, 2014. tab
Artigo em Espanhol | LILACS | ID: biblio-834794

RESUMO

En 1964 se publicó en la revista Antioquia Médica el primer trabajo original sobre la frecuencia de grupos sanguíneos en Medellín, dirigido por el Dr. Alberto Restrepo Mesa, uno de los pioneros de la Hematología en Colombia; posteriormente se realizaron dos importantes trabajos en los años 1999 y 2006, sin embargo, no se cuenta con reportes actuales. Objetivo: Establecer la frecuencia de los grupos sanguíneos en Medellín y el Valle de Aburrá, después de 50 años de publicada la primera investigación. Metodología: Se realizó un estudio observacional descriptivo con una muestra de 87.000 personas adultas, de ambos sexos, sin discriminación racial, que donaron hemoderivados en el banco de sangre del Hospital Pablo Tobón Uribe de la ciudad de Medellín (Colombia), entre 2000 y 2009, y se calculó la frecuencia de los grupos sanguíneos ABO y Rh...


At 1964, Antioquia Medica journal published the first original work of blood type frequencies in Medellin led by Dr. Alberto Restrepo Mesa, one of Hematology pioneers in Colombia; later there have been two important investigations in 1999 and 2006, however, there are not current reports. Objective: Establish the blood type frequencies in Medellin and the Valle de Aburrá after 50 years of the first published investigation. Methods: An observational descriptive study was made, with a sample of 87.000 adult people of both sexes, without racial discrimination, who donated blood at the Hospital Pablo Tobón Uribe blood bank of Medellin (Colombia) between 2000 and 2009; and frequency of ABO and Rh blood groups was calculated...


Assuntos
Humanos , Sistema ABO de Grupos Sanguíneos , Bancos de Sangue , Sistema do Grupo Sanguíneo Rh-Hr
8.
Biomédica (Bogotá) ; Biomédica (Bogotá);33(4): 643-652, Dec. 2013. ilus, tab
Artigo em Inglês | LILACS | ID: lil-700481

RESUMO

Introduction: The nCD64 receptor, the soluble triggering receptor expressed in myeloid cells (s-TREM-1), and the high mobility group-box 1 protein (HMGB-1) have been proposed as significant mediators in sepsis. Objective: To evaluate the prognostic value of these markers in patients with suspected infection recently admitted in an emergency department (ED). Materials and methods: All patients who presented to the ED with suspected infection were eligible for enrollment in this study. Baseline clinical data, Sequential Organ Failure Assessment score (SOFA) score, APACHE II score, HMGB-1 levels, s-TREM-1 levels, and nCD64 levels were analyzed. The HMGB-1 and sTREM-1 serum concentrations were determined using commercially available ELISA kits, and CD64 on the surface of neutrophils was measured by flow cytometry. Results:. A total of 579 patients with suspected infection as their admission diagnosis were enrolled in this study. The median patient age was 50 years (IQR = 35-68). Morbidity during the 28-day followup period was 11.1% (n=64). The most frequent diagnosis at the time of admission was communityacquired pneumonia (CAP) in 23% (n=133) patients, followed by soft tissue infection in 16.6% (n=96), and urinary tract infection in 15% (n=87). After multivariable analysis, no significant association was identified between any biomarker and 28-day mortality. Conclusion: In the context of a tertiary care hospital emergency department in a Latin-American city, the nCD64 receptor, s-TREM-1, and HMGB-1 biomarkers do not demonstrate prognostic utility in the management of patients with infection. The search continues for more reliable prognostic markers in the early stages of infection.


Introducción. El receptor CD64, receptor soluble ´desencadenador´ expresado en células mieloides (sTREM-1) y la proteína del grupo Box-1 de alta movilidad (HMGB-1), se han propuesto como mediadores en la sepsis. Objetivo. Evaluar el valor pronóstico de estos marcadores en pacientes con sospecha de infección, recientemente admitidos en un departamento de emergencias. Materiales y métodos. Se incluyeron en el estudio pacientes que consultaron al hospital con sospecha de infección. Se analizó la base de datos clínica, el puntaje SOFA, el puntaje APACHE II, los niveles de HMGB-1, los niveles de sTREM-1 y los niveles de nCD64. Se determinaron las concentraciones en suero de HMGB-1 y sTREM-1, usando kits de ELISA disponibles comercialmente, y la de CD64 se midió por citometría de flujo. Resultados. Se analizaron 579 pacientes con sospecha de infección al ingreso. La edad media fue de 50 años (rango intercuartílico=35-68), y 11,1 % (n=64) murieron durante el seguimiento de 28 días. El diagnóstico más frecuente en el momento del ingreso fue neumonía adquirida en la comunidad, en 23 % (n=133) de los pacientes, seguida de infección de tejidos blandos, en 16,6 % (n=96), e infección urinaria, en 15 % (n=87). Después de un análisis multivariado, no hubo asociación significativa entre ningún biomarcador y la mortalidad a los 28 días. Conclusión. Los resultados sugieren que en el contexto de un departamento de emergencias de tercer nivel de una ciudad latinoamericana típica, los tres marcadores evaluados no ofrecieron ninguna ventaja en el pronóstico de infección. La búsqueda de marcadores pronósticos más confiables en estadios tempranos de la infección aún continúa abierta.


Assuntos
Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Proteína HMGB1/sangue , Infecções/sangue , Glicoproteínas de Membrana/sangue , Neutrófilos/imunologia , Receptores de IgG/análise , Receptores de IgG/biossíntese , Receptores Imunológicos/sangue , Biomarcadores/sangue , Serviço Hospitalar de Emergência , Proteínas HMGB , Hospitalização , Neutrófilos/química , Prognóstico , Estudos Prospectivos
9.
Photomed Laser Surg ; 31(1): 36-40, 2013 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-23240876

RESUMO

OBJECTIVE: The purpose of this study was to evaluate the efficacy of GaAlAs laser light to reduce pain induced by post-adjustment orthodontic final archwire, compared with a placebo control group, and also to evaluate if there are differences in pain gradient when conventional brackets or self-ligating brackets are used for orthodontic treatment. BACKGROUND DATA: Previous reports indicate that laser therapy is a safe and efficient alternative to alleviate pain caused in the initial stages of treatment, but there are no studies about its efficacy during the last stages of orthodontic treatment. METHODS: The initial sample was 60 orthodontic patients from a private practice, treated by straight wire technique, 30 of them with mini brackets Equilibrium(®) (Dentaurum, Ispringen, Germany) and 30 with self-ligation In-Ovation C(®) (GAC/Dentsply, Tokyo, Japan) slot 0.022 inch brackets. The archwires used in the final stage of orthodontic treatment were stainless steel 0.019×0.025 inch, slot 0.022 inch in both groups. In a design of divided mouth, the dental arches were randomly assigned to receive one dental arch irradiation with 830 nm 100mW therapeutic laser (Photon Lase II), for 22 sec (2.2 J, 80 J/cm(2)) along the vestibular surface and 22 sec (2.2 J, 80 J/cm(2)) along the palatal surface of the root in the randomly selected arch. The opposite dental arch received placebo treatment, with the laser light off. Pain was evaluated using a visual analog scale (VAS) after 2, 6, and 24 h, and 2, 3, and 7 days of application. RESULTS: The time course of pain showed the same tendency in both groups, reaching a peak 24 h after the archwire activation. The application of laser therapy reduced pain for any period of time up to 7 days (p<0.00001) and for any kind of bracket. CONCLUSIONS: Low intensity laser application reduces pain induced by archwires used during the final stage of orthodontic treatment, without any interference regarding the kind of bracket, as reported by patients.


Assuntos
Terapia com Luz de Baixa Intensidade , Fios Ortodônticos/efeitos adversos , Dor/prevenção & controle , Técnicas de Movimentação Dentária/efeitos adversos , Adulto , Feminino , Humanos , Masculino , Medição da Dor , Adulto Jovem
10.
Biomedica ; 33(4): 643-52, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-24652218

RESUMO

INTRODUCTION: The nCD64 receptor, the soluble triggering receptor expressed in myeloid cells (s-TREM-1), and the high mobility group-box 1 protein (HMGB-1) have been proposed as significant mediators in sepsis. OBJECTIVE: To evaluate the prognostic value of these markers in patients with suspected infection recently admitted in an emergency department (ED). MATERIALS AND METHODS: All patients who presented to the ED with suspected infection were eligible for enrollment in this study. Baseline clinical data, Sequential Organ Failure Assessment score (SOFA) score, APACHE II score, HMGB-1 levels, s-TREM-1 levels, and nCD64 levels were analyzed. The HMGB-1 and sTREM-1 serum concentrations were determined using commercially available ELISA kits, and CD64 on the surface of neutrophils was measured by flow cytometry. RESULTS: . A total of 579 patients with suspected infection as their admission diagnosis were enrolled in this study. The median patient age was 50 years (IQR = 35-68). Morbidity during the 28-day followup period was 11.1% (n=64). The most frequent diagnosis at the time of admission was communityacquired pneumonia (CAP) in 23% (n=133) patients, followed by soft tissue infection in 16.6% (n=96), and urinary tract infection in 15% (n=87). After multivariable analysis, no significant association was identified between any biomarker and 28-day mortality. CONCLUSION: In the context of a tertiary care hospital emergency department in a Latin-American city, the nCD64 receptor, s-TREM-1, and HMGB-1 biomarkers do not demonstrate prognostic utility in the management of patients with infection. The search continues for more reliable prognostic markers in the early stages of infection.


Assuntos
Proteína HMGB1/sangue , Infecções/sangue , Glicoproteínas de Membrana/sangue , Neutrófilos/imunologia , Receptores de IgG/análise , Receptores de IgG/biossíntese , Receptores Imunológicos/sangue , Adulto , Idoso , Biomarcadores/sangue , Serviço Hospitalar de Emergência , Feminino , Proteínas HMGB , Hospitalização , Humanos , Masculino , Pessoa de Meia-Idade , Neutrófilos/química , Prognóstico , Estudos Prospectivos , Receptor Gatilho 1 Expresso em Células Mieloides
11.
Iatreia ; Iatreia;25(4): 323-333, oct.-dic. 2012. ilus, tab
Artigo em Espanhol | LILACS, COLNAL | ID: lil-659353

RESUMO

Introducción: las células mononucleares de la médula ósea son efectivas para el tratamiento de pacientes con enfermedad arterial periférica (EAP). Los factores de crecimiento que ellas sintetizan se usan para inducir angiogénesis. Objetivo: establecer en Colombia la seguridad, factibilidad y resultado del tratamiento de la EAP utilizando células autólogas, para evitar su progreso a estadios más avanzados. Métodos: previo consentimiento, se hizo aspirado de médula ósea bajo anestesia local. Las células obtenidas se concentraron y se inyectaron intramuscularmente en los gastrocnemios de las extremidades isquémicas. El grupo control retrospectivo no recibió células. La evaluación clínica incluyó varios parámetros. Las células se analizaron por citometría de flujo. Resultados: edad media de los pacientes: 69 ± 11 años; viabilidad celular: 99,15% ± 0,76%; número de células inyectadas: 9,2 x 108 ± 6,2 x 108. Los análisis angiográficos postratamiento mostraron formación de vasos colaterales nuevos en las extremidades afectadas, con mínimo engrosamiento. Se observaron aumento en la distancia caminada libre de dolor y mejoría del dolor en reposo. La obtención y aplicación de las células no se asoció con ninguna complicación. Conclusiones: este estudio preliminar demostró que la terapia celular autóloga es segura, factible y cambia positivamente la historia natural de la EAP. Se sugiere el estudio de un número mayor de pacientes antes de establecer este tratamiento en Colombia.


Introduction: Autologous bone marrow mononuclear cells have been shown to be safe and effective for treatment of patients with peripheral arterial disease (PAD). Angiogenesis can also be induced by growth factors synthesized by them. Objective: To determine in Colombia the feasibility, safety and outcome of the afore-mentioned treatment. Methods: After informed consent, bone marrow was obtained by aspiration under local anesthesia; mononuclear cells were concentrated and their number and viability were established. They were suspended in saline solution and implanted by intramuscular injection into the gastrocnemius muscles of ischemic legs. Control patients were left untreated. Clinical evaluation included several parameters. Flow cytometry was used for cell analysis. Results: Mean age of patients: 69 ± 11 years; cell viability: 99.15 ± 0.76%; total number of injected cells: 9.2 x 108 ± 6.2 x 108. After treatment, angiographic studies showed the formation of new collateral vessels in all patients, with minimal thickness increase. There were no complications from bone marrow aspiration and intramuscular administration of cells. All treated patients experienced increase in the walking distance and improvement of rest pain. Conclusions: These preliminary results demonstrate that autologous cell therapy is safe, feasible and positively changes the natural history of patients with advanced peripheral arterial disease. In order to establish this treatment as a current practice in Colombia, we suggest the study of a larger number of patients.


Assuntos
Humanos , Medula Óssea , Leucócitos Mononucleares , Extremidade Inferior , Doença Arterial Periférica , Artérias
12.
Acad Emerg Med ; 18(8): 807-15, 2011 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-21762470

RESUMO

OBJECTIVES: The objectives were to evaluate the diagnostic accuracy for sepsis in an emergency department (ED) population of the cluster of differentiation-64 (CD64) glycoprotein expression on the surface of neutrophils (nCD64), serum levels of soluble triggering receptor expressed on myeloid cells-1 (s-TREM-1), and high-mobility group box-1 protein (HMGB-1). METHODS: Patients with any of the following as admission diagnosis were enrolled: 1) suspected infection, 2) fever, 3) delirium, or 4) acute hypotension of unexplained origin within 24 hours of ED presentation. Levels of nCD64, HMGB-1, and s-TREM-1 were measured within the first 24 hours of the first ED evaluation. Baseline clinical data, Sepsis-related Organ Failure Assessment (SOFA) score, Acute Physiology and Chronic Health Evaluation (APACHE II) score, daily clinical and microbiologic information, and 28-day mortality rate were collected. Because there is not a definitive criterion standard for sepsis, the authors used expert consensus based on clinical, microbiologic, laboratory, and radiologic data collected for each patient during the first 7 days of hospitalization. This expert consensus defined the primary outcome of sepsis, and the primary data analysis was based in the comparison of sepsis versus nonsepsis patients. The cut points to define sensitivity and specificity values, as well as positive and negative likelihood ratios (LRs) for the markers related to sepsis diagnosis, were determined using receiver operative characteristics (ROC) curves. The patients in this study were a prespecified nested subsample population of a larger study. RESULTS: Of 631 patients included in the study, 66% (95% confidence interval [CI] = 62% to 67%, n = 416) had sepsis according with the expert consensus diagnosis. Among these sepsis patients, SOFA score defined 67% (95% CI = 62% to 71%, n = 277) in severe sepsis and 1% (95% CI = 0.3% to 3%, n = 6) in septic shock. The sensitivities for sepsis diagnosis were CD64, 65.8% (95% CI = 61.1% to 70.3%); HMGB-1, 57.5% (95% CI = 52.7% to 62.3%); and s-TREM-1, 60% (95% CI = 55.2% to 64.7%). The specificities were CD64, 64.6% (95% CI = 57.8% to 70.8%), HMGB-1, 57.8% (95% CI = 51.1% to 64.3%), and s-TREM-1, 59.2% (95% CI = 52.5% to 65.6%). The positive LR (LR+) for CD64 was 1.85 (95% CI = 1.52 to 2.26) and the negative LR (LR-) was 0.52 (95% CI = 0.44 to 0.62]; for HMGB-1 the LR+ was 1.36 (95% CI = 1.14 to 1.63) and LR- was 0.73 (95% CI = 0.62 to 0.86); and for s-TREM-1 the LR+ was 1.47 (95% CI = 1.22 to 1.76) and the LR- was 0.67 (95% CI = 0.57 to 0.79). CONCLUSIONS: In this cohort of patients suspected of having any infection in the ED, the accuracy of nCD64, s-TREM-1, and HMGB-1 was not significantly sensitive or specific for diagnosis of sepsis.


Assuntos
Biomarcadores/sangue , Proteína HMGB1/sangue , Glicoproteínas de Membrana/sangue , Receptores de IgG/sangue , Receptores Imunológicos/sangue , Sepse/diagnóstico , APACHE , Adulto , Idoso , Colômbia/epidemiologia , Estudos Transversais , Serviço Hospitalar de Emergência , Ensaio de Imunoadsorção Enzimática , Feminino , Glicoproteínas/sangue , Humanos , Masculino , Pessoa de Meia-Idade , Sensibilidade e Especificidade , Sepse/sangue , Sepse/epidemiologia , Receptor Gatilho 1 Expresso em Células Mieloides
13.
Univ. med ; 50(1): 111-118, ene.-mar. 2009. ilus
Artigo em Espanhol | LILACS | ID: lil-582173

RESUMO

En pacientes infectados con el virus de la inmunodeficiencia humana tipo 1 (VIH-1), la infección por citomegalovirus (CMV) ocurre principalmente en estadios avanzados de la enfermedad, especialmente cuando el recuento de células T CD4+ en sangre periférica se encuentra por debajo de 100 células/mm3, lo cual favorece la progresión al sida y aumenta la probabilidad de muerte. El compromiso de la retina es la manifestación más común de esta coinfección, pero existen otras manifestaciones, como la radiculopatía periférica, la encefalopatía y el compromiso gastrointestinal; en raras ocasiones se observa neumonitis. Esta coinfección también puede presentarse como un cuadro fatal, asociado con una viremia alta y persistente, y con un compromiso grave de varios órganos. La infección cutánea por CMV es una manifestación muy rara en los pacientes positivos para VIH-1, la cual se observa cuando el recuento de células T CD4+ es menor de 50/mm3 y cursa con úlceras crónicas en la piel o las mucosas.Se presentan las características clínicas e inmunológicas de un caso de infección cutánea por CMV en un paciente positivo para VIH-1, y se revisa la literatura.


In patients infected with the type 1-human immunodeficiency virus (HIV-1), the cytomegalovirus (CMV) infection occurs mainly in advanced stages of the disease, especially when the CD4+ T-cell count in under 100 cells/millilitre, which accelerates the progression to AIDS and increases the risk of death. The retina compromise is the most frequent manifestation of the CMV infection associated to HIV-1. Other manifestations include peripheralpolyradiculopathy, encephalopathy, andgastrointestinal compromise. Pneumonitis is rarely observed. In addition, this coinfection can be presented as a fatal disease associated with high and persistent viremia and severe compromise of several organs. The cutaneous CMV infection is a very rare manifestation in HIV-1-infected patients, which is observed when the CD4+ T-cell count is under 50 cells/millilitre, and course with chronicskin and mucosal ulcers. We present the clinic and immunological characteristicsof an HIV-1-infected individual with aCMV cutaneous infection, making a comprehensive review of literature published.


Assuntos
HIV-1 , Citomegalovirus
14.
Med. lab ; 15(1/2): 27-35, feb. 2009. graf
Artigo em Espanhol | LILACS | ID: lil-582192

RESUMO

Con el advenimiento de las pruebas moleculares de ácidos nucleicos (NAAT) a partir de 1998 para el virus de la hepatitis C (HCV), y posteriormente para el virus de la hepatitis B (HBV) y el virus de la inmunodeficiencia humana (HIV), se ha incrementado la seguridad relativa de la sangre comparada con las pruebas serológicas, y por tanto se ha reducido el período de ventana inmunológica...


Assuntos
Humanos , Transfusão de Sangue , Ácidos Nucleicos , Hepatite
15.
Rev. Estomat ; 15(1): 19-23, jul. 2007. ilus
Artigo em Espanhol | LILACS | ID: lil-565517

RESUMO

En este reporte de caso, un sistema de mini-implantes ortodóncicos vestibulares y palatinos, se utiliza para la intrusión de molares contribuyendo a la corrección de una mordida abierta dento-esquelética. Los aspectos tratados son: diagnóstico, tratamiento planteado, protocolo quirúrgico, consideraciones anatómicas, posibles complicaciones, curso del tratamiento, y presentación final del caso.


In this case report, a mini implant system that uses vestibular and palatal screws is presented as an excellent alternative for the treatment of and open bite case, it’s thru molar intrusion without any undesired transversal effect that the final results were achieved. The main topics treated are: diagnostic, treatment plan, surgical protocol, anatomic considerations, possible complications, curse of treatment, and final presentation of the case.


Assuntos
Mordida Aberta , Implantes Dentários , Equipamentos e Provisões , Técnicas de Movimentação Dentária
16.
Rev. colomb. cancerol ; 11(1): 40-57, mar. 2007. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-484497

RESUMO

El cáncer de mama es una de las primeras causas de muerte de mujeres en el mundo. En Colombia, es la segunda causa de muerte de mujeres por cáncer, después del cáncer de cuello uterino. Aunque no se ha establecido una causa específica para el desarrollo del cáncer, se sabe que el cáncer de mama es el resultado de la acumulación de daños en el ácido desoxirribonucleico (DNA) de las células del tejido mamario. Se han identificado numerosos genes cuyas alteraciones afectan el crecimiento normal de la célula, llevándola al desarrollo y progresión del cáncer de mama. Uno de estos genes es el HER2/neu. La proteína codificada por el gen HER2/neu se encuentra sobreexpresada en un 25porciento-30porciento de los cánceres de mama; así, el HER2/neu es el oncogén de más alta incidencia en esta enfermedad. Actualmente, existen diferentes métodos moleculares paraidentificar la amplificación de este gen o la expresión de su producto. Aunque sólo dos de estos métodos diagnósticos (la inmunohistoquímica y la hibridación fluorescente in situ) se encuentran aprobados por la Administración de Drogas y Alimentos de los Estados Unidos (FDA), la reacción en cadena de la polimerasa en tiempo real y la hibridación cromogénica in situ prometen ser los métodos diagnósticos del futuro. La importancia clínica de medir la amplificación del gen HER2/neu radica en que la sobreexpresión de la proteína HER2/neu indica peor pronóstico y, por lo tanto, cambio de tratamiento, como el empleo del anticuerpo monoclonal humanizado trastuzumab.


Breast cancer is one of the first causes of death in women on the world. In Colombia it is the second cause of death in women with cancer after the carcinoma of cervix uteri. Although the specific cause is not known, it is know that breast cancer is the result of the accumulation of damages in the DNA of the cells of the mammary tissue. Numerous genes have been identified whose alterations affect the normal growth of the cell, taking it to the development and progression of the breast cancer. One of these genes it is the HER2/neu. The protein codified by HER2/neu gene, is overexpressed in 25% to 30% of the breast cancer, the HER2/neu is the oncogen of higher incidence in the disease. At the present time different molecular methods exist to identify the amplification of this gene or the expression of their product. Although only two of these diagnostic methods (the Immunohistochemistry and the fluorescence in situ hybridization) they are approved by the Administration of Drugs and Foods of the United States of America (FDA), the polymerase chain reaction in real time and the cromogenic in situ hybridization, not yet approved by the FDA, promise to be the methods to be used to in the future diagnoses, due to his high sensitivity, specificity, easy handling and low costs. The clinical importance to measure the amplification of the HER2/neu gene is in which overexpression of the HER2/neu protein indicates worse prognosis, and therefore the change of treatment, like the use of the monoclonal antibody humanized trastuzumab.


Assuntos
Neoplasias da Mama , Genes , Reação em Cadeia da Polimerase , Imuno-Histoquímica , Hibridização de Ácido Nucleico
17.
Iatreia ; Iatreia;18(4): 377-384, oct.-dic. 2005. tab
Artigo em Espanhol | LILACS | ID: lil-635612

RESUMO

OBJETIVO: evaluar la utilidad del citoquímico de orina y la coloración de Gram en el diagnóstico de la infección del tracto urinario en pacientes hospitalizados. DISEÑO Y MUESTRA: estudio de corte transversal; 10.917 urocultivos. MÉTODOS: se hicieron el citoquímico de orina y la coloración de Gram de la orina sin centrifugar según la solicitud de los médicos tratantes. Cuando no se solicitó este último examen, la coloración de Gram se hizo del sedimento urinario. Se compararon los resultados obtenidos con el resultado del urocultivo. Resultados: se obtuvo el resultado del citoquímico de orina en 6.762 de las muestras. Se solicitaron 2.762 coloraciones de Gram de orina sin centrifugar, y en 8.008 orinas se hizo la coloración de Gram del sedimento urinario. En comparación con el urocultivo, el citoquímico de orina presentó sensibilidad del 99%, especificidad del 51%, valor predictivo positivo del 60%, y valor predictivo negativo del 98%. La coloración de Gram de la orina sin centrifugar tuvo sensibilidad, especificidad y valores predictivos positivo y negativo de 98%, 73%, 82% y 97%, respectivamente. Para la coloración de Gram del sedimento urinario los valores correspondientes a la sensibilidad, especificidad y valores predictivos positivo y negativo fueron 95%, 78%, 67%, y 97%. CONCLUSIONES: el citoquímico de orina, bajo los criterios propuestos, y la coloración de Gram tienen un alto valor predictivo negativo, que permitiría utilizarlos como pruebas de tamización para determinar la necesidad de solicitar el urocultivo.


OBJECTIVE: To evaluate the usefulness of urinalysis and of urine Gram stain in the diagnosis of urinary tract infection in hospitalized patients. DESIGN AND SAMPLE: Urinalysis and Gram stain of non centrifuged urine were carried out according to the requests of physicians, in specimens submitted to the laboratory for urine culture. When this modality of Gram stain had not been requested, it was done with urine sediment. Results were compared with those of the culture. RESULTS: Ten thousand nine hundred and seventeen urine cultures were carried out, as well as 6.762 urinalyses, 2.762 Gram stains of non centrifuged urine, and 8.008 Gram stains of urine sediments. In comparison with the urine culture, urinalyses had 99% sensitivity, 51% specificity, 60% positive predictive value, and 98% negative predictive value. Gram stain of non centrifuged urine had 98% sensitivity, 73% specificity, 82% positive predictive value, and 97% negative predictive value. Gram stain of urine sediment had 95% sensitivity, 78% specificity, 67% positive predictive value, and 97% negative predictive value. CONCLUSIONS: Urinalysis, following well defined criteria, and Gram stain have high negative predictive values, that may allow to use them as screening tests to determine the need to request urine culture.


Assuntos
Humanos , Doenças Urológicas , Coleta de Urina , Histocitoquímica
18.
Rev. bras. odontol ; 62(1/2): 92-96, 2005. ilus, tab
Artigo em Português | LILACS, BBO - Odontologia | ID: lil-427973

RESUMO

O objetivo deste estudo foi determinar quais marcas comerciais de luvas de látex apresentavam algum tipo de reação química impeditiva da polimerização completa das siliconas de adição (pasta densa e leve) pelo contato direto e indireto. Foi avalida a reação, de viscosidade leve e pesada, em contato direto com dez marcas comerciais de luvas de látex nacionais. A maior parte das luvas de látex testadas inibiu a polimerização da silicona de adição. Isso comprova que as siliconas de adição não devem entrar em contato com luvas de látex durante os procedimentos clínicos para evitar que sofram alterações das suas propriedades físico-químicas


Assuntos
Látex , Luvas Cirúrgicas/normas , Silicones/normas
19.
RGO (Porto Alegre) ; 51(5): 440-442, nov.-dez. 2003. ilus
Artigo em Português | LILACS, BBO - Odontologia | ID: lil-405562

RESUMO

Esta técnica aqui apresentada, demonstra a simplificação de um método para fabricação de uma placa oclusal estabilizadora, utilizando uma base de resina fotopolimerizável (Preci Tray Yeti), produzida pela Yeti Dentalprodulate, Industriosfrasse (Alemanha) e um aparelho fotopolimerizador para laboratório marca EDG. A maior vantagem desta técnica é a previsibilidade de sua pré-polimerização, pois permite resultados definitivos com relação ao trabalho final, já que é possível acrescentar fragmentos de resina ainda não ativados na matriz ou corpo principal da placa parcialmente fotopolimerizável.


Assuntos
Resinas Compostas , Placas Oclusais , Métodos
20.
Rev. méd. Chile ; 131(4): 390-396, abr. 2003. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-348366

RESUMO

Background: When the ascending aorta and the femoral artery cannot be used for extracorporeal circulation, an emerging alternative is the use of axillary artery. Aim: To report the experience using the axillary artery for extracorporeal circulation. Patients and methods: Between November 1998 and May 2002, 22 patients (14 male) were operated with extracorporeal circulation, cannulating the axillary artery. Briefly, an incision is made below the middle third of the clavicle and a cut is made on major pectoris muscle. Minor pectoris muscle is retracted and axillary artery is exposed. It is cannulated directly or with the aid of a prosthesis. Results: Right axillary artery was used in 21 patients and in 20 it was cannulated with the aid of a prosthesis. Mean flow was 4.5 + 0.6 l/min. The most common indications were aortic dissection or aneurysms. The most common procedures done, were ascending aorta replacement in 8 cases and replacement of ascending aorta and aortic arch in 5. Thirty five percent of operations were emergencies and 32 percent were reoperations. In 15 patients (68 percent), a circulatory arrest was done. Of these, retrograde brain perfusion was used in 9, antegrade brain perfusion through the same axillary artery was used in 2 and mixed perfusion was used in 2. One patient had a complication related to the axillary cannulation. None had cerebrovascular accidents or thromboembolic complications. Two patients died in the postoperative period. Patients were followed up to 42 months after the procedure and no secondary complications of the cannulation were detected. Conclusions: When the ascending aorta and the femoral artery cannot be used, axillary artery is a good alternative for extracorporeal circulation


Assuntos
Humanos , Masculino , Adulto , Feminino , Pessoa de Meia-Idade , Artéria Axilar , Circulação Extracorpórea/métodos , Cateterismo , Doenças Cardiovasculares , Aneurisma Aórtico/cirurgia , Coartação Aórtica/cirurgia
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