RESUMO
OBJECTIVE: This study aimed to compare the efficacy of CO 2 laser, radiofrequency, and promestriene in treating genitourinary syndrome of menopause in women with breast cancer receiving adjuvant therapy and to analyze the clinical and histological findings of the vulvar vestibule. METHODS: Women with moderate-to-severe symptoms of vulvar atrophy were enrolled. The participants were evaluated according to pretreatment and posttreatment protocols using the visual analog scale and clinical assessments, which included a gynecological examination and vestibular biopsy. Participants were randomly assigned into the laser, radiofrequency, or promestriene groups. Participants in the energy treatment groups underwent three consecutive monthly outpatient vulvovaginal treatment sessions, whereas those in the control group were administered promestriene for 4 months. During a follow-up visit 30 days posttreatment, the participant global posttreatment impression of improvement was evaluated using a Likert scale. RESULTS: Seventy women completed treatment. Histological vulvar atrophy was identified in four (5.7%) of the pretreatment vulvar samples. Postintervention, all histological parameters were normalized. Significant improvements in symptoms were observed, as all three groups showed a reduction in the visual analog scale score, with no statistically significant differences among them. A high level of satisfaction was reported posttreatment in all groups. No damage to the histological structure of the vulvar vestibule or relevant clinical adverse events were identified posttreatment. CONCLUSIONS: Laser, radiofrequency, and promestriene delivered comparable, significant symptom improvements among women with breast cancer receiving adjuvant therapy. These treatments did not cause structural tissue damage or other clinical complications.
Assuntos
Neoplasias da Mama , Sobreviventes de Câncer , Lasers de Gás , Feminino , Humanos , Neoplasias da Mama/terapia , Neoplasias da Mama/patologia , Menopausa , Lasers de Gás/uso terapêutico , Atrofia/patologia , Resultado do Tratamento , Vagina/patologiaRESUMO
OBJETIVO: Estudar a prevalência de início de vida sexual (IVS) e seus fatores associados em escolares do 8º ano da rede pública de Porto Velho-RO, em 2010. MATERIAL E MÉTODOS: estudo transversal com amostra representativa de 996 escolares analisada com teste T Student e regressão de Cox. RESULTADOS: a prevalência de IVS foi 25,5%. O IVS associou-se com sexo, idade, prática de atividades físicas, consumo de álcool, tabaco e drogas, falta às aulas sem o conhecimento dos pais, sentimento de tristeza e planejamento suicida. Os jovens que referiram que seus pais os entendem, que sabem onde estão no seu tempo livre e sentem discriminação apresentaram menos início de vida sexual. CONSIDERAÇÕES FINAIS: A escola deve discutir com seus alunos questões referentes à sexualidade e a estilos de vida saudáveis o mais precocemente possível, a fim de prepará-los para sua iniciação sexual e uma vida com mais qualidade.(AU)
OBJECTIVE: To study the prevalence of the beginning of sexual life (IVS) and related factors in school adolescents on the 8° year of the public school in Porto Velho-RO in 2010. MATERIAL AND METHODS: Transversal study with a representative sample of 996 school analyzed with t-Student test and Cox Regression. RESULTS: The prevalence of IVS was 25.5%. The IVS is associated with age, physical activity, alcohol, tobacco and drugs consumption, missing school without their parents' knowledge, sadness and suicidal plans. The adolescents, who reported that their parents understand them, know where they are in their free time and feel discrimination showed fewer sexual beginning. CONCLUSION: The school has to deal with the students questions related to sexuality and healthy lifestyle the early as possible, in a way to prepare them for their sexual initiation and a life with more quality.(AU)