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Introducción: Los síntomas neuropsicológicos son una preocupación importante para los pacientes con epilepsia y pueden llegar a ser muy influyentes en la percepción de calidad de vida. En el caso de la epilepsia del lóbulo temporal, existen muchas variables que influyen en el desempeño cognitivo de los pacientes, entre las más importantes se encuentran la etiología, la edad de inicio, la duración de la enfermedad y la frecuencia de crisis; sin embargo, una de las variables más importantes es la lateralidad de la epilepsia. Está claramente demostrado que los síntomas cognitivos de la epilepsia del lóbulo temporal varían en función del hemisferio cerebral afectado. Contenido: La epilepsia del lóbulo temporal es una de las principales epilepsias focales que es susceptible de manejo quirúrgico, y, en este sentido, el tipo de procedimiento también tiene una gran importancia en el desenlace cognitivo de estos pacientes. En este artículo, realizamos una revisión narrativa de la literatura, con el objetivo de describir el riesgo neuropsicológico relacionado no solamente con la epilepsia del lóbulo temporal per se, sino también con las intervenciones quirúrgicas que se realizan en pacientes refractarios a la medicación. Conclusiones: Es importante conocer los conceptos sobre las implicaciones del impacto cognitivo en los pacientes con epilepsia del lóbulo temporal antes de tomar decisiones quirúrgicas en pacientes refractarios, así como entender que el tipo de cirugía también influye en su desempeño cognitivo. Se debe buscar un equilibrio entre la libertad de crisis y las posibles secuelas neuropsicológicas posquirúrgicas.
Introduction: Neuropsychological symptoms are a major concern for patients with epilepsy and can highly influence the perception of quality of life. In the case of temporal lobe epilepsy, there are many variables that impact the cognitive performance of these people, among the most important are the etiology, the age of onset, the duration of the disease and the frequency of seizures, however, one of the most important variables is the lateralization of the seizure. It has been demonstrated that the cognitive symptoms of temporal lobe epilepsy vary depending on the affected cerebral hemisphere. Contents of the review: Temporal lobe epilepsy is one of the main focal epilepsies that is susceptible to surgical management, and the type of surgery also has great importance in the cognitive outcomes of these patients. In this article, we carry out a narrative review of the literature in order to describe the neuropsychological risk related not only to temporal lobe epilepsy per se, but also to surgical interventions performed in drug-resistant patients. Conclusions: It is important to know the concepts about the implications of cognitive impact in patients with temporal lobe epilepsy before making surgical decisions in refractory patients and to understand that the type of surgery also influences the cognitive performance of these patients. A balance must be sought between the freedom of seizures and the possible postoperative neuropsychological sequelae.
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Lobo Temporal , Epilepsia Resistente a Medicamentos , Lateralidade Funcional , Qualidade de Vida , Idioma , MemóriaRESUMO
Predictions of hospital beds occupancy depends on hospital admission rates and the length of stay (LoS) according to bed type (general ward -GW- and intensive care unit -ICU- beds). The objective of this study was to describe the LoS of COVID-19 hospital patients in Colombia during 2020-2021. Accelerated failure time models were used to estimate the LoS distribution according to each bed type and throughout each bed pathway. Acceleration factors and 95% confidence intervals were calculated to measure the effect on LoS of the outcome, sex, age, admission period during the epidemic (i.e., epidemic waves, peaks or valleys, and before/after vaccination period), and patients geographic origin. Most of the admitted COVID-19 patients occupied just a GW bed. Recovered patients spent more time in the GW and ICU beds than deceased patients. Men had longer LoS than women. In general, the LoS increased with age. Finally, the LoS varied along epidemic waves. It was lower in epidemic valleys than peaks, and decreased after vaccinations began in Colombia. Our study highlights the necessity of analyzing local data on hospital admission rates and LoS to design strategies to prioritize hospital beds resources during the current and future pandemics.
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COVID-19 , Masculino , Humanos , Feminino , Tempo de Internação , Estudos de Coortes , Colômbia/epidemiologia , COVID-19/epidemiologia , Unidades de Terapia Intensiva , Hospitais , Estudos RetrospectivosRESUMO
Socioeconomic disparities play an important role in the development of severe clinical outcomes including deaths from COVID-19. However, the current scientific evidence in regard the association between measures of poverty and COVID-19 mortality in hospitalized patients is scant. The objective of this study was to investigate whether there is an association between the Colombian Multidimensional Poverty Index (CMPI) and mortality from COVID-19 in hospitalized patients in Colombia from May 1, 2020 to August 15, 2021. This was an ecological study using individual data on hospitalized patients from the National Institute of Health of Colombia (INS), and municipal level data from the High-Cost Account and the National Administrative Department of Statistics. The main outcome variable was mortality due to COVID-19. The main exposure variable was the CMPI that ranges from 0 to 100% and was categorized into five levels: (i) level I (0%-20%), (ii) level II (20%-40%), (iii) level III (40%-60%), (iv) level IV (60%-80%); and (v) level V (80%-100%). The higher the level, the higher the level of multidimensional poverty. A Bayesian multilevel logistic regression model was applied to estimate Odds Ratio (OR) and their corresponding 95% credible intervals (CI). In addition, a subgroup analysis was performed according to the epidemiological COVID-19 waves using the same model. The odds for dying from COVID-19 was 1.46 (95% CI 1.4-1.53) for level II, 1.41 (95% CI 1.33-1.49) for level III and 1.70 (95% CI 1.54-1.89) for level IV hospitalized COVID-19 patients compared with the least poor patients (CMPI level I). In addition, age and male sex also increased mortality in COVID-19 hospitalized patients. Patients between 26 and 50 years-of-age had 4.17-fold increased odds (95% CI 4.07-4.3) of death compared with younger than 26-years-old patients. The corresponding for 51-75 years-old patients and those above the age of 75 years were 9.17 (95% CI 8.93-9.41) and 17.1 (95% CI 16.63-17.56), respectively. Finally, the odds of death from COVID-19 in hospitalized patients gradually decreased as the pandemic evolved. In conclusion, socioeconomic disparities were a major risk factor for mortality in patients hospitalized for COVID-19 in Colombia.
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COVID-19 , Humanos , Masculino , Adulto , Idoso , Pessoa de Meia-Idade , COVID-19/epidemiologia , Colômbia/epidemiologia , Disparidades Socioeconômicas em Saúde , Teorema de Bayes , Fatores de RiscoRESUMO
Resumen La educación para personas con Diabetes Mellitus (DM) representa un desafío en el campo de la salud pública. Presentamos una propuesta teórica que orienta el análisis pedagógico de la educación para la salud en personas con DM, a partir de un proceso de investigación documental. Los hallazgos evidenciaron la existencia de diferentes perspectivas teóricas en tensión sobre la educación en personas con DM que luchan por la legitimación, que pueden agruparse en dos tendencias, una tradicional y la otra crítica. Se presenta una propuesta guiada desde la teoría pedagógica y la salud pública para explicar los hallazgos. La teoría construida pretende evidenciar la configuración de corrientes educativas como resultado de los debates y las luchas teóricas, políticas y epistemológicas que se dan en la intersección de los campos de la salud pública y la pedagogía. (AU)
Abstract Education for people with Diabetes Mellitus (DM) represents a challenge in the field of public health. We present a theoretical proposal that guides the pedagogical analysis of health education for people with DM, based on a documentary research process. The findings evidenced the existence of different theoretical perspectives in tension about education in people with DM that struggle for legitimacy, which can be grouped into two tendencies, one traditional and the other critical. A proposal guided by pedagogical theory and public health is presented to explain the findings. The theory constructed intends to evidence the configuration of educational currents as a result of the debates and theoretical, political and epistemological struggles that occur at the intersection of the fields of public health and pedagogy. (AU)
Resumo A educação para pessoas com Diabetes Mellitus (DM) representa um desafio no campo da saúde pública. Apresentamos uma proposta teórica que orienta a análise pedagógica da educação em saúde em pessoas com DM, a partir de um processo de pesquisa documental. Os achados evidenciaram a existência de diferentes perspectivas teóricas em tensão sobre a educação em pessoas com DM que lutam por legitimação, que podem ser agrupadas em duas correntes, uma tradicional e outra crítica. Uma proposta pautada na teoria pedagógica e na saúde pública é apresentada para explicar os achados. A teoria construída visa mostrar a configuração das correntes educacionais como resultado dos debates e lutas teóricas, políticas e epistemológicas que ocorrem na intersecção dos campos da saúde pública e da pedagogia. (AU)
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Introduction: Hip fractures are a pathology of traumatic origin that generates a high impact on public health. The objective is to evaluate the interobserver reproducibility of the Tronzo classification for intertrochanteric fractures. Methods: Observational, analytical and retrospective study carried out in Ibagué - Colombia, 48 hip radiographs were analyzed, classified by 10 observed among specialists and training personnel, using the Tronzo classification. Interobserver reproducibility is assessed using the kappa concordance coefficient. Results: Among all those observed in the study, there is greater agreement in the identification of intertrochanteric fractures of lesser and greater severity (Tronzo I and V), the main exponents of this agreement are the most experienced staff, the staff in training, with intermediate experience they agree when identifying those of intermediate severity and for those with less experience the concordance becomes evident when evaluating the intermediate grades. Conclusion: The concordance increases with the experience for the identification of the types with high complexity. This classification is not suitable for clinical practice, another system is necessary for this type of fracture in clinical conduct.
Introducción: Las fracturas de cadera son una patología de origen traumático que genera un alto impacto en la salud pública. El objetivo es evaluar la reproducibilidad interobservador de la clasificación de Tronzo para fracturas intertrocantéricas. Métodos: Estudio observacional, analítico y retrospectivo realizado en Ibagué Colombia, se analizaron 48 radiografías de cadera, clasificadas por 10 observado entre especialistas y personal en formación, utilizando la clasificación de Tronzo. La reproducibilidad interobservador se evalúa mediante el coeficiente de concordancia kappa. Resultados: Entre todos los observados del estudio existe mayor acuerdo en la identificación de fracturas intertrocantéricas de menor y mayor gravedad (Tronzo I y V), los principales exponentes de este acuerdo son el personal de mayor experiencia, el personal en formación, con experiencia intermedia están de acuerdo al identificar a los de gravedad intermedia y para los que tienen menos experiencia la concordancia se hace evidente a la hora de evaluar los grados intermedios. Conclusión: La concordancia aumenta con la experiencia para la identificación de los tipos con alta complejidad. No es adecuado para la práctica clínica esta clasificación, es necesario otro sistema para este tipo de fracturas en las conductas clínicas.
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INTRODUCTION: Diabetes has been associated with an increased risk of complications in patients with COVID-19. Most studies do not differentiate between patients with type 1 and type 2 diabetes, which correspond to two pathophysiological distinct diseases that could represent different degrees of clinical compromise. OBJECTIVE: To identify if there are differences in the clinical outcomes of patients with COVID-19 and diabetes (type 1 and type 2) compared to patients with COVID-19 without diabetes. METHODS: Observational studies of patients with COVID-19 and diabetes (both type 1 and type 2) will be included without restriction of geographic region, gender or age, whose outcome is hospitalization, admission to intensive care unit or mortality compared to patients without diabetes. Two authors will independently perform selection, data extraction, and quality assessment, and a third reviewer will resolve discrepancies. The data will be synthesized regarding the sociodemographic and clinical characteristics of patients with diabetes and without diabetes accompanied by the measure of association for the outcomes. The data will be synthesized regarding the sociodemographic and clinical characteristics of patients with diabetes and without diabetes accompanied by the measure of association for the outcomes. EXPECTED RESULTS: Update the evidence regarding the risk of complications in diabetic patients with COVID-19 and in turn synthesize the information available regarding type 1 and type 2 diabetes mellitus, to provide keys to a better understanding of the pathophysiology of diabetics. SYSTEMATIC REVIEW REGISTRY: This study was registered at the International Prospective Registry for Systematic Reviews (PROSPERO)-CRD42021231942.
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COVID-19 , Diabetes Mellitus Tipo 2 , COVID-19/complicações , Diabetes Mellitus Tipo 2/complicações , Hospitalização , Humanos , Unidades de Terapia Intensiva , Estudos Observacionais como Assunto , Revisões Sistemáticas como AssuntoRESUMO
BACKGROUND: Various well-validated interview and self-report instruments are available to assess eating disorder symptomatology. However, most psychometric studies have been conducted in high-income countries. The aim of the present study was to systematically review the available psychometric studies conducted in low- and middle-income countries on well-known measures for assessing eating disorder symptoms. METHODS: Psychometric studies with the following instruments were included: the Eating Disorder Examination (EDE), the Eating Disorder Examination Questionnaire (EDE-Q), the Eating Disorder Inventory (EDI), the Eating Attitudes Test (EAT), and the Children's Eating Attitudes Test (ChEAT). Searches were conducted on August 30, 2021, in the following databases: MEDLINE, EMBASE, LILACS, Web of Science, PsycINFO, and CABI. The methodological quality of the studies was assessed using the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN). The studies were considered to have conducted the minimum psychometric evaluation if they assessed at least the three types of validity (content, criteria, and construct) or diagnostic performance. The psychometric properties were also evaluated considering the cut-off points described in the literature for each of the analysis methods used to evaluate validity and reliability and two reviewers independently selected the studies and evaluated the quality criteria. RESULTS: A total of 28 studies were included. The studies were conducted in 13 countries (10 middle income and 3 low income). The instruments that were most used in the studies were the EAT and EDE-Q. According to the overall COSMIN assessment, in most (57%) of the studies the psychometric properties assessed were not described. Forty-three percent of the studies conducted the minimum psychometric evaluation. However, according to the described cut-off points, the results for the psychometric properties assessed showed, in general, acceptable validity and reliability. CONCLUSION: The results of this review suggest a lack of studies with the recommended psychometric properties in low- and middle-income countries on these commonly used instruments. With the steady increase in the prevalence of eating disorders globally, psychometric investigations of instruments for measuring eating disorder symptoms in these countries should be encouraged to promote their early detection and treatment.
The prevalence of eating disorders has increased worldwide. Various instruments are available to assess eating disorder symptomatology, but most psychometric studies have been conducted in high-income countries. The current study aimed to systematically review studies from low- and middle-income countries that have examined the psychometric properties of commonly used measures for assessing eating disorder symptoms. The findings of this study suggest a lack of research in low- and middle-income countries on the psychometric properties of commonly used eating disorder instruments. To promote the early detection and treatment of eating disorder symptoms, instruments with adequate psychometric properties must be available worldwide.
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BACKGROUND: Providing optimal care for type 2 diabetes (DM2) patients remains a challenge for all healthcare systems. Patients often encounter various barriers in adhering to self-management programs due to lack of knowledge and understanding of self-care activities, lack of individualized and coordinated care, inconvenient and costly education sessions, and poor patient-provider communication. Mobile technologies such as cell phones/smartphones, handheld tablets, and other wireless devices offer new and exciting opportunities for addressing some of these challenges. The purpose of this study is to compare a diabetes management strategy using an information board and a mobile application versus standard care in patients with uncontrolled DM2. METHOD: The SANENT (Sistema de Análisis de Enfermedades No Transmisibles) trial is a primary care-based, prospective, two-arm, randomized controlled, open-label, blinded-endpoint study. We aim to recruit 1440 DM2 patients during a period of 6 months until the requested number of participants has been achieved. The total length of the intervention will be 1 year. Both men and women treated for DM2 with an HbA1c > 8.5% and ≥ 20 years of age are eligible to participate in the study. The primary outcome of the study is improved diabetes control measured by changes in HbA1c in the study participants. HbA1c will be measured at baseline, 3-month, 6-month, 9-month, and 12-month follow-up visits in all participants. The main analysis will be based on the intention-to-treat principle. The primary endpoint of the study will be the change in HbA1C within the groups and the differences between the groups. This will be assessed by a repeated measurement approach based on mixed models which contain both fixed effects and random effects. DISCUSSION: The overall goal of this project is to contribute to the evidence for the use of mobile technology to improve the treatment and regulation of poorly controlled DM2 patients living in Mexico. Our proposed project will show how mobile health technology tools can be used in the treatment of patients with uncontrolled DM2 in primary health care in a Latin American population, and particularly how they could help diabetes patients take better care of themselves. TRIAL REGISTRATION: ClinicalTrials.gov , US National Institutes of Health NCT04974333 . Prospectively registered on July 13, 2021. Protocol version number 1, dated August 15th, 2021.
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Diabetes Mellitus Tipo 2 , Aplicativos Móveis , Diabetes Mellitus Tipo 2/diagnóstico , Diabetes Mellitus Tipo 2/terapia , Feminino , Humanos , Sistemas de Informação , Masculino , México , Atenção Primária à Saúde , Estudos Prospectivos , Ensaios Clínicos Controlados Aleatórios como Assunto , Estados UnidosRESUMO
Water deficits are the major constraint in some potato-growing areas of the world. The effect is most severe at the tuberization stage, resulting in lower yield. Therefore, an assessment of genetic and phenotypic variations resulting from water deficits in Colombia germplasm is required to accelerate breeding efforts. Phenotypic variations in response to a water deficit were studied in a collection of Solanum tuberosum Group Phureja. A progressive water deficit experiment on the tuberization stage was undertaken using 104 genotypes belonging to the Working Collection of the Potato Breeding Program at the Universidad Nacional de Colombia. The response to water deficit conditions was assessed with the relative chlorophyll content (CC), maximum quantum efficiency of PSII (Fv/Fm), relative water content (RWC), leaf sugar content, tuber number per plant (TN) and tuber fresh weight per plant (TW). Principal Component Analysis (PCA) and cluster analysis were used, and the Drought Tolerance Index (DTI) was calculated for the variables and genotypes. The soluble sugar contents increased significantly under the deficit conditions in the leaves, with a weak correlation with yield under both water treatments. The PCA results revealed that the physiological, biochemical and yield-component variables had broad variation, while the yield-component variables more powerfully distinguished between the tolerant and susceptible genotypes than the physiological and biochemical variables. The PCA and cluster analysis based on the DTI revealed different levels of water deficit tolerance for the 104 genotypes. These results provide a foundation for future research directed at understanding the molecular mechanisms underlying potato tolerance to water deficits.
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The global manufacturing sector faces a significant challenge about minimizing environmental impacts without witnessing the adverse effects on the market competitiveness. A cleaner production methodology must involve different approaches for minimizing or recycling waste streams, obtaining at the same time economical and environmental advantages for manufacturing companies (Severo et al., J Clean Prod 142:87-97, 2017). In the polypropylene production process, more than 60 grades of polypropylene are produced. To achieve this target, changes in the process variables are carried out, due to the continuous operation process. Those changes generate a mixture of resins with intermediate properties (transition), which must be minimized. Moreover, failures during the transitions process generate a large extra amount of material that represents a significant impact on the environment, when it is considered as waste. In this paper, an environmental analysis was made by applying a waste reduction algorithm (WAR) to establish the potential impact of a polypropylene production process over the environment, applying grade transitions strategies and then to demonstrate how the improvement of transition times implies a significant reduction of plastic waste. It was found that the reduction of transitions time minimizes the environmental impact based on real industry data. Last should be considered for the real polymer plant analyzed and future projects.
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Meio Ambiente , Polipropilenos , Gerenciamento de Resíduos/métodos , Algoritmos , Colômbia , Plásticos , ReciclagemRESUMO
RESUMEN El objetivo del presente artículo es determinar cómo se vieron afectadas las condiciones laborales del sector agropecuario colombiano, dentro del marco de efectos sociales, tras la firma del acuerdo de promoción comercial entre Colombia y Estados Unidos. Para esto, se realizó una adaptación macroeconómica de los indicadores GRI versión G4 en la categoría desempeño social. Esta adaptación permitió analizar la información sectorial y aplicarlos en la población laboral del sector agropecuario colombiano. La metodología utilizada fue cualitativa con énfasis en un método de lista de comprobación y análisis de indicadores, y se encontraron dos resultados importantes. En primer lugar, que el acuerdo comercial entre ambos países es superficial al momento de salvaguardar las condiciones laborales del sector, sin profundizar en aspectos específicos que reglamenten el contexto laboral. En segundo lugar, se evidenció que a pesar de los aumentos significativos en las tasas de contrataciones, las afiliaciones a entidades prestadoras de salud o administradoras de riesgos profesionales de empleados, la mayor parte del sector agropecuario colombiano opera bajo la informalidad. Finalmente, se puede afirmar que las condiciones laborales del sector agropecuario colombiano, dentro del marco de efectos sociales, tras la firma del acuerdo de promoción comercial entre Colombia y Estados Unidos no se vieron afectadas de manera positiva. La informalidad y la falta de regulación sigue siendo un factor común en el sector.
ABSTRACT The objective of this article is to determine how the labor conditions of the Colombian agricultural sector were affected, within the framework of social effects, after the signing of the Trade Promotion Agreement between Colombia and the United States. For this, a macroeconomic adaptation of GRI indicators version G4 in the social performance category was made. This adaptation made it possible to analyze sectoral information and apply it to the labor population of the Colombian agricultural sector. The methodology used was qualitative with emphasis on a checklist method and analysis of indicators, and two important results were found. First, that the trade agreement between both countries is superficial at the moment of safeguarding the labor conditions of the sector, without going into specific aspects that regulate the labor context. Secondly, it was evident that despite the significant increases in contracting rates, affiliations with health providers or managers of occupational risks for employees, most of the Colombian agricultural sector operates under informality. Finally, it can be affirmed that the labor conditions of the Colombian agricultural sector, within the framework of social effects, after the signing of the Trade Promotion Agreement between Colombia and the United States were not affected in a positive manner. Informality and lack of regulation continues to be a common factor in the sector.
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Humanos , Categorias de Trabalhadores , PopulaçãoRESUMO
BACKGROUND: The global epidemiology of type 1 diabetes (T1D) is not yet well known, as no precise data are available from many countries. T1D is, however, characterized by an important variation in incidences among countries and a dramatic increase of these incidences during the last decades, predominantly in younger children. In the United States and Europe, the increase has been associated with the gross domestic product (GDP) per capita. In our previous systematic review, geographical variation of incidence was correlated with socio-economic factors. AIM: To investigate variation in the incidence of T1D in age categories and search to what extent these variations correlated with the GDP per capita. METHODS: A systematic review was performed to retrieve information about the global incidence of T1D among those younger than 14 years of age. The study was carried out according to the PRISMA recommendations. For the analysis, the incidence was organized in the periods: 1975-1999 and 2000-2017. We searched the incidence of T1D in the age-groups 0-4, 5-9 and 10-14. We compared the incidences in countries for which information was available for the two periods. We obtained the GDP from the World Bank. We analysed the relationship between the incidence of T1D with the GDP in countries reporting data at the national level. RESULTS: We retrieved information for 84 out of 194 countries around the world. We found a wide geographic variation in the incidence of T1D and a worldwide increase during the two periods. The largest contribution to this increase was observed in the youngest group of children with T1D, with a relative increase of almost double when comparing the two periods (P value = 2.5 × e-5). Twenty-six countries had information on the incidence of T1D at the national level for the two periods. There was a positive correlation between GDP and the incidence of T1D in both periods (Spearman correlation = 0.52 from 1975-1999 and Spearman correlation = 0.53 from 2000-2017). CONCLUSION: The incidence increase was higher in the youngest group (0-4 years of age), and the highest incidences of T1D were found in wealthier countries.
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RESUMEN El lupus eritematoso sistémico (LES) es una enfermedad crónica que expone a los pacientes a situaciones estresantes físicas, psíquicas, familiares, laborales y sociales. Se conoce que la calidad de vida relacionada con la salud de estos pacientes es inferior a la de la población general y que el estrés está relacionado con el empeoramiento del LES. El estudio de los factores que determinan la percepción del paciente con LES permitiría conocer los mecanismos que inciden negativamente en la calidad de vida y promover intervenciones que conlleven su mejoría. Objetivo: Conocer la percepción que los pacientes con LES tienen acerca de su enfermedad. Metodología: Cincuenta pacientes (11 hombres) con LES y sin otras enfermedades autoinmunes participaron en 5 grupos focales, realizados por un médico psiquiatra mediante la aplicación de entrevista semiestructurada. Utilizando la teoría fundamentada, las transcripciones fueron categorizadas en 3 fases: codificación abierta, axial y selectiva. Resultados: Se organizaron en 7 categorías: noticia del diagnóstico; causas de la enfermedad; consecuencias funcionales, sociales y laborales; dificultades para establecer el diagnóstico; los tratamientos no farmacológicos o alternativos; baja adherencia y rechazo al tratamiento farmacológico; fallas identificadas por los pacientes en la atención en salud y conciencia de la enfermedad. Conclusiones: El conocer la percepción que tiene el paciente con LES de su enfermedad les permite al médico, al paciente y a su familia adoptar medidas encaminadas a diseñar intervenciones puntuales y eficaces para el manejo integral, adherencia al tratamiento, disminución de morbilidad asociada y de costos derivados de la atención médica.
ABSTRACT Systemic lupus erythematosus (SLE) exposes patients to physical, psychological, family, work and social stress factors. The health-related quality of life of these patients is less than that of the general population, and stress is associated with worsening symptoms of SLE. Studying the factors that determine the perceptions of an SLE patient toward their disease would allow understanding the mechanisms by which quality of life is adversely affected, and promote interventions that ensure the well-being of these patients. Objective: To gain knowledge of the perceptions that SLE patients have regarding their disease. Methodology: A total of 50 patients (11 of them men) participated in 5 focus groups that were guided by a psychiatrist applying a semi-structured interview. The interview transcripts were categorised into the following 3 phases using grounded theory: open, axial and selective coding. Results: The results were organised into 7 categories: news of the diagnosis; causes of the disease; functional, social and work consequences; difficulties in establishing a diagnosis; non-pharmacological, alternative treatments, low or non-adherence and rejection of drug treatment; weaknesses in health care identified by the patient; and disease awareness. Conclusions: Knowing the perception that SLE patients have of their disease allows the physician, the patient, and the patient's family to take steps toward designing timely and effective interventions for integrated disease management, treatment adherence, and reducing the associated morbidity and costs of medical care.
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Humanos , Adulto , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Grupos Focais , Lúpus Eritematoso Sistêmico , Psiquiatria , Doença Crônica , EntrevistaRESUMO
Objetivo Averiguar ¿Cuál de los dos factores es más nocivo? ¿Cuál es la magnitud de su efecto? y ¿Qué pasa cuando alguien se expone a ambos factores a la vez? Métodos Estudio ecológico que evalúa la asociación epidemiológica (riesgo relativo) entre la contaminación atmosférica y el tabaquismo con la función pulmonar, evaluada mediante espirometría funcional en 489 adultos. Se comparan dos ambientes con diferentes niveles de contaminación, 30 y 60 µg/m³ de material particulado respirable (PM10) y grupos de fumadores contra no fumadores. Resultados La función pulmonar está disminuida (VEF1<80 %) en los fumadores en mayor proporción que en los no fumadores, con un exceso de riesgo de 52 % (RR. 1,52 IC95 % 1,11-2,07). Las personas expuestas a un mayor nivel de contaminación ambiental presentan una mayor proporción de disfunción pulmonar con un exceso de riesgo de 64 % (RR. 1,64 IC95 % 1,19-2,25). Cuando los sujetos se exponen a ambos factores, es decir fuman y además se encuentran en ambientes contaminados, el exceso de riesgo es del 129 % (RR 2,29 IC95 % 1,45-3,61). Conclusiones Las personas que respiran ambientes contaminados presentan disfunción pulmonar en una magnitud similar o superior a la que presentan los fumadores, es decir, podríamos afirmar que en relación con los efectos, respirar aire contaminado equivale a estar fumando, solo que en contra de la voluntad.(AU)
Objective We want to determine: ¿Which of the two factors is more harmful? ¿What is the magnitude of its effect? and ¿What happens when someone is exposed to both factors at once?. Methods An ecological study that evaluates the epidemiological association (relative risk) between air pollution and smoking with lung functions as assessed by functional spirometry in 489 adults. We compare two environments with different pollution levels 30 and 60 g/m³ of particulate matter (PM10) and groups of smokers against nonsmokers. Results Lung function is impaired (FEV1 <80 %) in smokers at higher rates than the non-smokers, with an excess risk of 52 % (RR. 1.52 CI 95 % 1.11 -2.07). People exposed to higher levels of pollution have a higher proportion of pulmonary dysfunction than those exposed to less polluted environments with an excess risk of 64 % (RR. 1,64 CI 95% 1.19-2.25). When subjects are exposed to both factors, that is smokers who also live in contaminated environments, the excess of risk reaches 129 % (RR 2.29 CI 95 % 1.45-3.61). Conclusions People who breathe in polluted environments have impaired lung function in a similar magnitude or greater than smokers. Therefore, we could say that breathing contaminated air is equivalent to smoking, but sadly it occurs against the affected party's will.(AU)
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Humanos , Nicotiana/efeitos adversos , Poluição do Ar/efeitos adversos , Pneumopatias/etiologia , Espirometria/instrumentação , Estudos EcológicosRESUMO
Objective We want to determine: ¿Which of the two factors is more harmful? ¿What is the magnitude of its effect? and ¿What happens when someone is exposed to both factors at once?. Methods An ecological study that evaluates the epidemiological association (relative risk) between air pollution and smoking with lung functions as assessed by functional spirometry in 489 adults. We compare two environments with different pollution levels 30 and 60 g/m³ of particulate matter (PM10) and groups of smokers against nonsmokers. Results Lung function is impaired (FEV1 <80 %) in smokers at higher rates than the non-smokers, with an excess risk of 52 % (RR. 1.52 CI 95 % 1.11 -2.07). People exposed to higher levels of pollution have a higher proportion of pulmonary dysfunction than those exposed to less polluted environments with an excess risk of 64 % (RR. 1,64 CI 95% 1.19-2.25). When subjects are exposed to both factors, that is smokers who also live in contaminated environments, the excess of risk reaches 129 % (RR 2.29 CI 95 % 1.45-3.61). Conclusions People who breathe in polluted environments have impaired lung function in a similar magnitude or greater than smokers. Therefore, we could say that breathing contaminated air is equivalent to smoking, but sadly it occurs against the affected party's will.
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INTRODUCTION: The prevalence of osteoporosis in premenopausal women along with associated risk factors has not been well elucidated. Recent studies have shown that poverty is a risk factor for osteoporosis. OBJECTIVE: To determine the prevalence of osteoporosis and its risk factors in a group of premenopausal women of poor economic background in Colombia. MATERIALS AND METHODS: The study comprised 1483 women between 35 and 53 years of age with at least one risk factor for osteoporosis. Demographic characteristics, reproductive factors, comorbidities, and risk factors for osteoporosis were evaluated. Lumbar vertebrae (L2-L4) and the femur neck were assessed using dual-energy X-ray absorptiometry. RESULTS: Of the 1483 patients, 1443 (97.3%) had at least one risk factor for osteoporosis and 40 (2.7%) had no risk factors. Patients with one risk factor were referred to have a dual-energy X-ray absorptiometry scan, which 795 women completed. Osteopenia was found in 30.5% and osteoporosis in 4.8% of these women. The majority of these women were homemakers, and 18.5% of the patients with osteoporosis were also illiterate (P < 0.001). The risk factors identified in this population were: hypothyroidism (odds ratio [OR] = 5.19, 95% confience interval [CI]:1.6-16), age over 45 years old (OR = 1.13, 95% CI: 1.0-1.2), a history of malnutrition or low birth weight (OR = 2.35, 95% CI: 1.0-5.2), or early-onset menopause (OR = 3.4, 95% CI: 1.6-7.2). CONCLUSION: Premenopausal Colombian women from impoverished areas showed increased rates of osteopenia and osteoporosis compared with the data described in the current literature. Hypothyroidism was an outstanding risk factor in Colombian premenopausal women with osteoporosis. This shows the influence of poverty and other risk factors on the onset of osteoporosis in women aged 35-53 years.
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Objective. To identify the theoretical conceptions of health education (HE) reported by recent scientific literature.Methodology. Systematic review without meta-analysis of the scientific literature published on the theory on HE between 2000 and 2010 in Spanish, English, and Portuguese in PubMed, Elsevier, and SciELO. This included publications developing at least the theoretical categories on HE: conceptual development, history, current situation, as discipline, teaching and research.Results. Some 58 articles on HE were analyzed. The main categories contained in the articles were those of current situation and conceptual development. The definition and conceptualizationof HE are diffuse. Most authors state that the term HE lacks identity and that tension exists between this concept and that of Healthcare Promotion. Conclusion. Processes in HE are notsufficiently qualified.
Objetivo. Identificar las concepciones teóricas de la Educación para la Salud (EpS) reportadas por la literatura científica reciente. Metodología. Revisión sistemática sin meta-análisis de la literatura científica publicada sobre la teoría en EpS entre 2000 y 2010 enespañol, inglés y portugués en PubMed, Elsevier y Scielo. Se incluyeron aquellas publicaciones que desarrollaran al menos las categorías teóricas sobre EpS: desarrollo conceptual, historia,situación actual, como disciplina, enseñanza e investigación.Resultados. Se analizaron 58 artículos sobre EpS. Las principales categorías contenidas en los artículos fueron los de situación actual y desarrollo conceptual. La definición y la conceptuaciónde EpS son difusas. La mayoría de los autores afirman que el término EpS carece de identidad y que existe tensión entre este concepto y el de Promoción para la Salud. Conclusión. Los procesos en EpS no están suficientemente cualificados
Objetivo. Identificar as concepções teóricas da educação para a saúde (EpS) reportadas pela literatura científica recente. Metodologia. Revisão sistemática sem meta-análise da literatura científica publicada sobre a teoria em EpS entre 2000 e 2010 em espanhol, inglês e português em PubMed, Elsevier e Scielo. Incluíram-se aquelas publicações que desenvolvessem ao menos as categorias teóricas sobre EpS: desenvolvimento conceitual, história, situação atual, como disciplina, ensino e investigação. Resultados. Analisaram-se 58 artigos sobre EpS. As principais categorias contidas nos artigos foram os de situação atual e desenvolvimento conceitual. A definição e a conceptualização de EpS são difusas. A maioria dos autores afirmam que o termo EpS carece de identidade e que existe tensão entre este conceito e o de Promoção para a Saúde. Conclusão. Os processos em EpS não estão suficientemente qualificados.
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Humanos , Artigo de Revista , Educação em Saúde , RevisãoRESUMO
La pielonefritis enfisematosa (PE) es una entidad clínica inusual, que constituye una infección necrotizante aguda con formación de gas en el parénquima renal, sistema colector y/o espacio perirrenal. La población diabética es claramente más propensa a este tipo de pielonefritis, sin embargo, se han descrito casos de PE recurrente en pacientes con obstrucción de la vía urinaria en ausencia de diabetes mellitus. En cerca del 69 por ciento al 97 por ciento de los casos, el germen implicado en la génesis de la enfermedad es la Escherichia coli, seguido por la Klebsiella pneumoniae, responsables de una enfermedad con alto impacto en la morbimortalidad de los pacientes diabéticos. Por lo tanto, el familiarizarnos con esta entidad clínica, nos permitirá realizar un diagnóstico precoz con el fin de establecer el tratamiento más adecuado que permita una mejor sobrevida en el paciente.