RESUMO
La investigación tuvo como objetivo, determinar el efecto de la masticación de Erythroxylum coca Lamarck (Coca) sobre los niveles de colesterol y triglicéridos séricos en personas altoandinas, la población fue de 100 personas altoandinas, 50 mujeres y 50 varones como masticadores, conformando grupos control con personas no masticadoras. Previa entrevista y los exámenes de laboratorio se obtuvieron los siguientes resultados, para el grupo control: los niveles de colesterol (201.75 mg% varones y 193.50 mg% mujeres) y niveles de triglicéridos (174 mg% varones y 134 mg% mujeres). En comparación con el grupo de problema o masticadores: cuyos niveles de colesterol (155 mg % varones y 150 mg % mujeres) y niveles de triglicéridos (84 mg % varones y 55 mg % mujeres) siendo estadísticamente significativos con la prueba de ANVA y el coeficiente de correlación simple es positiva y directa. Por lo que se concluye: que las personas que realizan la masticación de hojas de coca no son obesas. Además, el extracto de hojas de coca no facilita la digestión de alimentos grasos como el colesterol y triglicéridos al inhibir la actividad enzimática.
The objective of the research was to determine the effect of chewing Erythroxylum coca. Lamarck (Coca) on serum cholesterol and triglyceride levels in high Andean people, the population was 100 high Andean people, 50 women and 50 men as chewers, forming control groups with non-chewers. After an interview and laboratory tests, the following results were obtained for the control group: cholesterol levels (201.75 mg % men and 193.50 mg % women) and triglyceride levels (174 mg % men and 134 mg % women). Compared with the problem group or chewers: whose cholesterol levels (155 mg % men and 150 mg % women) and triglyceride levels (84 mg % men and 55 mg % women) being statistically significant with the ANVA test, and the simple correlation coefficient is positive and direct. Therefore, it is concluded: that people who chew coca leaves are not obese. In addition, the extract of coca leaves does not facilitate the digestion of fatty foods such as cholesterol and triglyc-erides by inhibiting the enzymatic activity.
Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Triglicerídeos , Colesterol , Coca , Peru , Ecossistema AndinoRESUMO
A superoxide dismutase excreted by promastigote forms of L. (Viannia) peruviana (SODe-Lp), L. (Viannia) brazilensis (SODe-Lb), and L. (L.) amazonensis (SODe-La) is tested to evaluate its potential value as a diagnostic tool of mucocutaneous and Andean cutaneous leishmaniasis. We used 45 sera with mucocutaneous leishmaniasis (SL) and 68 with Andean cutaneous leishmaniasis (ACL). SODe-Lp antigen was recognized by 94% of the serum from ACL patients, and the SODe-Lb antigen was recognized by 93% of the serum from SL patients. Meanwhile, the result for SL and ACL patients with SODe-La antigen was 69% and 43% and SODe-Li was 11% and 9%, respectively. This suggest that antibodies to SODe-Lp undergo further response in patients with ACL and the antibodies to SODe-Lb do so preferentially in patients with SL. The SODe ELISA may be useful in endemic areas for discriminative assays between patients with different forms of leishmaniases and those with other clinical conditions.