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OBJECTIVE: To analyze the impact of COVID-19 pandemics on lifestyle-related etiquettes like eating, physical activity, and sleep behavior among nursing staff in India. METHODS: A crosssectional descriptive E-survey was conducted among 942 nursing staff. The validated electronic survey questionnaire was used to assess the changes in lifestyle-related etiquette before and during COVID-19 Pandemic. RESULTS: Pandemic. Results. A total of 942 responses (mean age 29.01±5.7years) were collected, 53% of the respondents were men. A slight decline in healthy meal consumption pattern (p<0.0001) and a restriction of unhealthy food items were observed (p<0.0001), and also reduction in physical activity coupled with decreased participation in leisure-related activities was seen (p<0.0001). The stress and anxiety slightly increase during COVID-19 pandemics (p<0.0001). Additionally, social support extended by family and friends to maintain healthy lifestyle-related behaviors also significantly decreased during COVID-19 PANDEMIC pandemics compared to before (p<0.0001). Although the COVID-19 Pandemic slightly reduced the intake of healthy meals and deterred participants from consuming unhealthy food, this this may have led to individual weight loss. CONCLUSIONS: In general, there was a negative impact on, lifestyle like diet, sleep and mental health was observed. A detailed understanding of these factors can help to develop interventions to mitigate the harmful lifestyle-related etiquette that has manifested during COVID-19 Pandemic.
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COVID-19 , Masculino , Humanos , Adulto Jovem , Adulto , Feminino , SARS-CoV-2 , Estudos Transversais , Pandemias , Estilo de Vida , Inquéritos e QuestionáriosRESUMO
En el lenguaje médico, el uso de epónimos es frecuente. Si bien comúnmente se piensa que los epónimos están en vías de extinción, eso no es totalmente cierto. Existe disenso entre quienes creen que su uso debería abandonarse y quienes abogan que los epónimos convierten términos inmemorables en memorizables, transmiten conceptos complejos y promueven el interés en la historia de la Medicina. Nos sentimos parte de ese segundo grupo y nuestra intención es hacer una revisión de ocho epónimos vinculados a la Anatomía y Radiología de cabeza y cuello. Creemos que ese abordaje puede ser útil para la educación de estudiantes de Medicina, residentes y especialistas en diagnóstico por imágenes.
The use of eponyms in medical language is frequent. While it is commonly thought that eponyms are on their way to extinction, this is not entirely true. There is dissent between those who believe that their use should be abandoned and those who advocate that eponyms make unmemorable terms memorable, convey complex concepts and promote interest in the history of medicine. We feel part of this second group, and our intention is to make a review of eight eponyms linked to head and neck anatomy and radiology. We believe that this approach can be useful for the education of medical students, residents and diagnostic imaging specialists.
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Abstract Peripheral cemento-ossifying fibroma (PCOF) is a reactive gingival over growth, occurring frequently in the maxillary anterior region of teenage and young females. Peripheral cemento-ossifying fibroma (PCOF) is supposed to be originating from periosteum and/or periodontal ligament. A large number of factors have been implicated in the pathogenesis of PCOF, which includes trauma, local irritation, calculus and hormonal disturbances. The definitive diagnosis of PCOF is based upon its clinical, radiological and histological features. Because of the high recurrence rate (8-20%) of PCOF, a close post-operative follow-up is required. Herewith, we are presenting a case of PCOF in 24-year old female patient at an uncommon location.
Resumen El fibroma cemento-osificante periférico (PCOF, por sus siglas en inglés) es un crecimiento gingival reactivo, que se produce con frecuencia en la región anterior del maxilar en adolescentes y mujeres jóvenes. Se supone que el fibroma cemento-osificante periférico (PCOF) se origina en el periostio y/o el ligamento periodontal. Una gran cantidad de factores han sido implicados en la patogénesis de PCOF, dentro de las que se incluye trauma, irritación local, cálculo y alteraciones hormonales. El diagnóstico definitivo de PCOF se basa en sus características clínicas, radiológicas e histológicas. Debido a la alta tasa de recurrencia (8-20%) , se requiere un seguimiento post-operatorio estricto. Mediante este artículo presentamos un caso de PCOF en una paciente de 24 años de edad y el manejo teraupético.
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Humanos , Feminino , Adulto , Cementoma/complicações , Mandíbula/cirurgia , Doenças da BocaRESUMO
BACKGROUND: There are limited data on illness understanding and perception of cure among advanced cancer patients around the world. The aim of the study was to determine the frequency and factors associated with inaccurate perception of curability among advanced cancer patients receiving palliative care across the globe. MATERIALS AND METHODS: Secondary analysis of a study to understand the core concepts in end-of-life care among advanced cancer patients receiving palliative care from 11 countries across the world. Advanced cancer patients were surveyed using a Patient Illness Understanding survey and Control Preference Scale. Descriptive statistics and multicovariate logistic regression analysis were performed. RESULTS: Fifty-five percent (763/1,390) of patients receiving palliative care inaccurately reported that their cancer is curable. The median age was 58, 55% were female, 59% were married or had a partner, 48% were Catholic, and 35% were college educated. Sixty-eight percent perceived that the goal of therapy was "to get rid of their cancer," and 47% perceived themselves as "seriously ill." Multicovariate logistic regression analysis shows that accurate perception of curability was associated with female gender (odds ratio [OR] 0.73, p = .027), higher education (OR 0.37, p < .0001), unemployment status (OR 0.69, p = .02), and being from France (OR 0.26, p < .0001) and South Africa (OR 0.52, p = .034); inaccurate perception of curability was associated with better Karnofsky performance status (OR 1.02 per point, p = .0005), and being from Philippines (OR 15.49, p < .0001), Jordan (OR 8.43, p < .0001), Brazil (OR 2.17, p = .0037), and India (OR 2.47, p = .039). CONCLUSION: Inaccurate perception of curability in advanced cancer patients is 55% and significantly differs by gender, education, performance status, employment status, and country of origin. Further studies are needed to develop strategies to reduce this misperception of curability in advanced cancer patients. IMPLICATIONS FOR PRACTICE: The findings of this study indicate that inaccurate perception of curability among advanced cancer patients is 55%. Inaccurate perception of curability significantly differs by gender, education, performance status, employment status, and country of origin. There is great need to facilitate improved patient-physician communication so as to improve health care outcomes and patient satisfaction.
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Atitude Frente a Saúde , Neoplasias/psicologia , Neoplasias/terapia , Cuidados Paliativos/psicologia , Adulto , Idoso , Comunicação , Tomada de Decisões , Feminino , Humanos , Cooperação Internacional , Masculino , Pessoa de Meia-Idade , Neoplasias/patologia , Relações Médico-Paciente , Prognóstico , Assistência Terminal/psicologiaRESUMO
Accurately identifying Mycobacterium bovis-infected cattle is critical for bovine tuberculosis prevention and control. One method for identifying infected cattle is an ELISA developed by IDEXX laboratories, which detects antibodies to two M. bovis proteins, MPB70 and MPB83. The assay's sensitivity varies by geographic region, with sensitivities of 77%, 45%, and 9% in bovine serum samples from the United Kingdom (n = 126), the United States (n = 146), and Mexico (n = 128), respectively. We hypothesized that geographically-biased sequence variation in mpb70 and mpb83, or in the genes that regulate their expression (sigK and rskA), may explain these differing sensitivities. This hypothesis was tested by comparing the sequences of these four genes in 455 M. bovis strains isolated from cattle in the aforementioned countries. For each gene, a single, common sequence was identified in most genomes of the M. bovis strains collected in all three countries. Twelve of the 455 strains were isolated from infected cattle for which the IDEXX ELISA was also performed. Five of the seven ELISA-positive genomes and three of the five ELISA-negative genomes contained the most common sequence of all four genes. Thus, sequence variation in mpb70, mpb83, sigK, and rskA does not explain the geographic disparities in IDEXX ELISA sensitivity.
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Proteínas de Bactérias/genética , Mycobacterium bovis/classificação , Mycobacterium bovis/genética , Análise de Sequência de DNA/métodos , Tuberculose Bovina/diagnóstico , Animais , Anticorpos Antibacterianos/metabolismo , Antígenos de Bactérias/genética , Antígenos de Bactérias/imunologia , Proteínas de Bactérias/imunologia , Bovinos , Ensaio de Imunoadsorção Enzimática , Variação Genética , Proteínas de Membrana/genética , Proteínas de Membrana/imunologia , México , Mycobacterium bovis/imunologia , Sensibilidade e Especificidade , Tuberculose Bovina/imunologia , Reino Unido , Estados UnidosRESUMO
ABSTRACT Corn husks are the major wastes of corn industries with meagre economic significance. The present study was planned for value addition of corn husk through extraction of xylan, followed by its enzymatic hydrolysis into xylooligosaccharides, a pentose based prebiotic. Compositional analysis of corn husks revealed neutral detergent fibre 68.87%, acid detergent fibre 31.48%, hemicelluloses 37.39%, cellulose 29.07% and crude protein 2.68%. Irrespective of the extraction conditions, sodium hydroxide was found to be more effective in maximizing the yield of xylan from corn husks than potassium hydroxide (84% vs. 66%). Application of xylanase over the xylan of corn husks resulted into production of xylooligosaccharides with different degree of polymerization namely, xylobiose and xylotriose in addition to xylose monomer. On the basis of response surface model analysis, the maximum yield of xylobiose (1.9 mg/ml) was achieved with the enzymatic hydrolysis conditions of pH 5.8, temperature 44°C, enzyme dose 5.7U/ml and hydrolysis time of 17.5h. Therefore, the corn husks could be used as raw material for xylan extraction vis a vis its translation into prebiotic xylooligosaccharides.
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PURPOSE: To compare the clinical presentation of prostatic abscess and treatment outcome in two different time frames with regards to etiologies, co-morbid factors and the impact of multidrug resistant organism. MATERIALS AND METHODS: We retrospectively assessed the charts of 48 patients with the diagnosis of prostatic abscess from 1991 to 2005. The period was divided arbitrarily into two different time frames; phase I (1991-1997) and phase II (1998-2005). Factors analyzed included presenting features, predisposing factors, imaging, bacteriological and antibiotic susceptibility profile, treatment and its outcome. RESULTS: The mean patient age in phase I (n = 18) and phase II (n = 30) were 59.22 +/- 11.02 yrs and 49.14 +/- 15.67 respectively (p = 0.013). Diabetes mellitus was most common predisposing factor in both phases. Eleven patients in phase II had no co-morbid factor, of which nine were in the younger age group (22 - 44 years). Of these eleven patients, five presented with pyrexia of unknown origin and had no lower urinary tract symptoms LUTS. Two patients with HIV had tuberculous prostatic abscess along with cryptococcal abscess in one in phase II. Two patients had melioidotic prostatic abscess in phase II. The organisms cultured were predominantly susceptible to first line antibiotics in phase I whereas second or third line in phase II. CONCLUSION: The incidence of prostatic abscess is increasing in younger patients without co-morbid factors. The bacteriological profile remained generally unchanged, but recently multi drug resistant organisms have emerged. A worrying trend of HIV infection with tuberculous prostatic abscess and other rare organism is also emerging.
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Abscesso/microbiologia , Antibacterianos/efeitos adversos , Infecções por Enterobacteriaceae/complicações , Doenças Prostáticas/microbiologia , Abscesso/patologia , Adulto , Antibacterianos/uso terapêutico , Brasil , Complicações do Diabetes/tratamento farmacológico , Diagnóstico Diferencial , Farmacorresistência Bacteriana Múltipla/fisiologia , Infecções por Enterobacteriaceae/tratamento farmacológico , Febre/microbiologia , Humanos , Masculino , Pessoa de Meia-Idade , Doenças Prostáticas/patologia , Estudos Retrospectivos , Fatores de Tempo , Resultado do TratamentoRESUMO
PURPOSE: To compare the clinical presentation of prostatic abscess and treatment outcome in two different time frames with regards to etiologies, co-morbid factors and the impact of multidrug resistant organism. MATERIALS AND METHODS: We retrospectively assessed the charts of 48 patients with the diagnosis of prostatic abscess from 1991 to 2005. The period was divided arbitrarily into two different time frames; phase I (1991-1997) and phase II (1998-2005). Factors analyzed included presenting features, predisposing factors, imaging, bacteriological and antibiotic susceptibility profile, treatment and its outcome. RESULTS: The mean patient age in phase I (n = 18) and phase II (n = 30) were 59.22 ± 11.02 yrs and 49.14 ± 15.67 respectively (p = 0.013). Diabetes mellitus was most common predisposing factor in both phases. Eleven patients in phase II had no co-morbid factor, of which nine were in the younger age group (22 - 44 years). Of these eleven patients, five presented with pyrexia of unknown origin and had no lower urinary tract symptoms LUTS Two patients with HIV had tuberculous prostatic abscess along with cryptococcal abscess in one in phase II. Two patients had melioidotic prostatic abscess in phase II. The organisms cultured were predominantly susceptible to first line antibiotics in phase I whereas second or third line in phase II. CONCLUSION: The incidence of prostatic abscess is increasing in younger patients without co-morbid factors. The bacteriological profile remained generally unchanged, but recently multi drug resistant organisms have emerged. A worrying trend of HIV infection with tuberculous prostatic abscess and other rare organism is also emerging.
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Adulto , Humanos , Masculino , Pessoa de Meia-Idade , Abscesso/microbiologia , Antibacterianos/efeitos adversos , Infecções por Enterobacteriaceae/complicações , Doenças Prostáticas/microbiologia , Abscesso/patologia , Antibacterianos/uso terapêutico , Brasil , Diagnóstico Diferencial , Complicações do Diabetes/tratamento farmacológico , Farmacorresistência Bacteriana Múltipla/fisiologia , Infecções por Enterobacteriaceae/tratamento farmacológico , Febre/microbiologia , Doenças Prostáticas/patologia , Estudos Retrospectivos , Fatores de Tempo , Resultado do TratamentoRESUMO
A Gram-negative, rod-shaped, psychrophilic, motile, non-spore-forming bacterium, strain U1T, was isolated from Ushuaia located at the southernmost tip of Argentina. On the basis of 16S rRNA gene sequence similarity, strain U1T was found to be closely related to Marinomonas communis (DSM 5604T) and Marinomonas primoryensis (IAM 15010T). At the DNA-DNA level, however, the values for similarity were 41 and 25 %, respectively. The major fatty acids present were iso-C(16 : 0), C(16 : 1)omega7c, iso-C(17 : 1) and C(18 : 1)omega7c and the G+C content of the DNA was 43.6 mol%. All of the above characteristics support the affiliation of strain U1T to the genus Marinomonas. Furthermore, on the basis of phenotypic features, chemotaxonomic characteristics and phylogenetic analysis of the 16S rRNA gene sequence, it appears that strain U1T is distinct from the four Marinomonas species with validly published names. Strain U1T, therefore, represents a novel species, for which the name Marinomonas ushuaiensis sp. nov. is proposed. The type strain of M. ushuaiensis is U1T (=MTCC 6143T=DSM 15871T=JCM 12170T).