RESUMO

In the present work, we report the synthesis and characterization of five (4-alkylalmino-4'-fluoro)-diphenyl sulphones, four of which have not been described before. In a preliminary evaluation of their biological activity, these products showed no effect on several Gram-positive and Gram-negative bacteria and yeasts.

Assuntos

Anti-Infecciosos , Antifúngicos/síntese química , Sulfonas , Anti-Infecciosos , Antifúngicos/farmacologia , Bactérias Gram-Negativas/efeitos dos fármacos , Bactérias Gram-Positivas/efeitos dos fármacos , Relação Estrutura-Atividade , Sulfonas , Leveduras