RESUMO
OBJECTIVE: To evaluate the safety of repeated applications of permethrin concentrations (0% control, 1.5%, 5%, and 10%) to the necks and faces of horses and assess the efficacy and longevity of permethrin as an equine tick repellent. ANIMALS: 5 healthy adult Quarter Horses. PROCEDURES: Each treatment was applied to the neck of each horse (0.01 m2) 4 times a day, for up to 10 days. An 8-mm biopsy was taken to evaluate postexposure dermal responses. Any treatments that were not withdrawn were applied to a quadrant of the horse's face 4 times a day, for up to 5 days. For tick bioassays, a treatment was applied to 1 leg of a horse and 5 female blacklegged ticks (Ixodes scapularis) were evaluated as "repelled" or "not repelled" by the treatment. The bioassays were repeated up to 5 days, but treatment application took place only on the first day of the experiment. RESULTS: Histological results of neck biopsies indicated that more repeated exposures or higher concentrations resulted in more dermal damage. Tick bioassays showed that 5% and 10% permethrin had the greatest efficacy and longevity as a tick repellent, but the differences in tick repellency were not significant overall. CLINICAL RELEVANCE: While there was a nonsignificant trend of higher permethrin concentrations repelling more ticks with longer-lasting residual repellent effects, higher concentrations also produced greater skin damage after repeated exposures. These opposing findings emphasize the need for better tick prevention and control methods that balance safety and efficacy for the equine community.
Assuntos
Doenças do Cão , Doenças dos Cavalos , Ixodes , Cavalos , Animais , Feminino , Cães , Ixodes/fisiologia , Permetrina/farmacologia , Permetrina/uso terapêutico , Doenças do Cão/tratamento farmacológicoRESUMO
Understanding the frequency, duration, and intensity of exercise is important for determining the optimal diet and management of horses. The objective of the study was to characterize the exercise management of horses in Pennsylvania. An online survey was distributed from February 27th to August 31st, 2020. Respondents were asked to place their horse in an exercise category, as well as report on frequency and duration of exercise and time spent at each gait. Nonparametric statistics (mdn=median) and tests were used when data were not normally distributed. Of the 470 horses, 68% were regularly exercised. The exercised horses were classified as 49% (135/275) in light, 41% (113/275) in moderate, and 12% (32/275) in heavy/very heavy exercise. Of those exercised, 43% (120/278) were ridden recreationally (not used for competition). The median minutes per week spent exercising was 180 minutes (IQR=183). The average number of exercise sessions per week was 3.6 ± 2.2. Horses in heavy/very heavy (mdn=220 min, IQR=272) and moderate exercise (mdn=180 min, IQR=180) spent more minutes exercising per week compared to light exercise (mdn=120 minute, IQR=180; P< .05). Total number of exercise sessions completed per week differed between horses in light (mdn=2 sessions, IQR=3), moderate (mdn=4 sessions, IQR=2), and heavy/very heavy exercise (mdn=6 sessions, IQR=2; P < .05). Horses were exercised for a similar duration and frequency per week compared to previous studies. Some challenges exist for placing horses in NRC exercise categories based on self-reports only.