RESUMO

Renal cysts occur in approximately 50% of patients with tuberous sclerosis complex, but their clinical significance and response to treatment are unknown. Abdominal imaging of 15 patients with tuberous sclerosis complex-associated renal cystic disease who had received mammalian target of rapamycin inhibitor therapy for other tuberous sclerosis complex-related indications was evaluated. Reductions in cyst number, sum diameter, and volume were observed.

Assuntos

Imunossupressores/uso terapêutico , Doenças Renais Císticas/tratamento farmacológico , Sirolimo/uso terapêutico , Esclerose Tuberosa/complicações , Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Rim/patologia , Doenças Renais Císticas/etiologia , Imageamento por Ressonância Magnética , Masculino , Resultado do Tratamento , Esclerose Tuberosa/tratamento farmacológico , Adulto Jovem