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The management of skin burns is still challenging. Among the therapeutic methods used, there are topical treatments with pharmacological and herbal agents, low-intensity therapeutic ultrasound, use of biomaterials, reconstructive techniques and photobiomodulation therapy. The aim of this study was to evaluate the effects of photobiomodulation with blue Light Emitting Diode (LED) on burn healing. Fifty Wistar rats were divided into control (CTRL) (n = 25) and blue LED (LED) (n = 25), with subgroups (n = 5) for each time of euthanasia (7, 14, 21, 28 and 32 days). Treated animals were daily irradiated (470 nm, 1W, 0.44 W/cm2, 50 J/cm2). Clinical evaluations were performed and the Wound Retraction Index (WRI) was determined. Histological sections were submitted to hematoxylin-eosin, toluidine blue and the immunohistochemical technique, with anti-α-SMA and anti-TGF-ß1 antibodies. All data were directly collected by previously calibrated evaluators in a blind manner. The values were included in a statistical program. For all statistical tests used, 5% significance level (p < 0.05) was considered. No statistically significant differences in WRI between groups were observed (p > 0.05). Re-epithelialization was higher using LED at 7 and 14 days (p < 0.05) and greater amount of inflammatory cells was observed at 7 days (p = 0.01). With LED at 21 and 32 days, greater number of mast cells were observed (p < 0.05), as well as smaller number of myofibroblasts at 14, 21, 28 and 32 days (p < 0.05) and lower percentage of TGF-ß1 positive cells in the conjunctiva at 7, 14 and 21 days (p < 0.05). Negative correlations were observed in LED between the percentage of TGF-ß1 in the epithelium and the mean number of inflammatory cells and number of myofibroblasts (p < 0.05). The results suggest that, depending on the period, blue LED can modulate the healing processes of third-degree skin burns, such as re-epithelialization, inflammatory response, mast cell concentration, myofibroblast differentiation and TGF-ß1 immunoexpression. Despite these effects, this therapy does not seem to have significant influence on the retraction of these wounds. Future studies, using different protocols, should be carried out to expand the knowledge about the photobiomodulatory mechanisms of this type of light in the healing process.

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The aim of this study was to evaluate the effects of red light emitting diode (LED) photobiomodulation therapy protocol on inflammatory cells during the healing of third-degree skin burns. Fifty Wistar rats were randomly divided into control group (CTRL) (n = 25) and red group (RED) (n = 25), with subgroups (n = 5) for each time of euthanasia (7, 14, 21, 28, and 32 days). Treatment animals were daily irradiated (630 nm ± 10 nm, 300 mW, 9 J/cm2 per point, 30 s, continuous emission mode) at the 4 angles of the wound (total: 36 J/cm2). After specimen removal, histological sections were stained with hematoxylin and eosin for quantitative analysis of the inflammatory infiltrate (neutrophils and lymphocytes) under light microscopy. Greater number of inflammatory cells was observed in irradiated groups when compared to CTRL at 7, 14, 21, and 28 days, but with statistically significant difference only at 14 days (p = 0.02). At 32 days, higher inflammatory cell value was observed in CTRL when compared to RED, but with no statistically significant difference (p = 0.91). The results suggest that red LED, according to the protocol used, modulates the number of inflammatory cells in the early stages of the healing of third-degree skin burns. Nevertheless, this low-intensity light therapy may not, be efficient in reducing the number of neutrophils and lymphocytes in advanced stages of the repair process of skin burns. Further studies with other therapy protocols are needed to assess the effects of this type of light on the inflammatory response of skin burns.

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This systematic review aimed to evaluate the effectiveness of low-level laser therapy in controlling postoperative pain in lower third molar extractions. A search was carried out in MEDLINE/PubMed, Web of Science and Cochrane Library (CENTRAL) databases, using the "low-level laser therapy", "photobiomodulation therapy", "impacted mandibular third molar", "mandibular third molar", "third molar extraction" descriptors and 2625 studies were found, including only randomized clinical trials published until July 2020, with no restrictions on language and country of study. Selected studies were submitted to initial screening based on the reading of titles, abstracts and full article, and duplicate studies were excluded. Overall, 2562 articles were found, of which only 15 randomized clinical trials were included in this review. A total of 648 patients (16-44 years) who received low-level laser therapy as an intervention and placebo in their control group were evaluated. The pain evaluation criterion was the Visual Analog Scale (VAS) on the second and seventh days after surgery. Photobiomodulation with low-level laser showed statistically significant reduction in postoperative pain in lower third molar extractions, both on the second (MD: - 0.59; CI: - 0.92, - 0.27) and seventh day after surgery (MD: - 0.76; CI: - 1.21, - 0.32).

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O objetivo deste estudo foi relacionar a distribuição dos cursos de Odontologia, número de cirurgiões-dentistas(CD)ePIBper capita em municípios paraibanos com cursos de graduação em Odontologia. Trata-se de um estudo transversal descritivo com utilização de dados coletados diretamente dossites do Conselho Federal de Odontologia, do Instituto Brasileiro de Geografia e Estatísticae do Cadastro Nacional de Cursose Instituições de Ensino Superior. Todos os dados utilizados nesta pesquisa são de acesso público. AParaíba possui 16 cursos de graduação em Odontologia, distribuídos em 6 munícipios: Araruna (1; 6,25%), Cabedelo (1; 6,25%), Cajazeiras (2; 12,50%), Campina Grande (6; 37,50%), João Pessoa (4; 25,00%) e Patos (2; 12,50%).Os municípios com maiores valores de PIB per capita, como João Pessoa (R$24.319,82) e Campina Grande (R$21.077,30), apresentaram também maior número de CD, com uma correlação positiva entre os valores do PIB per capitade cada município e a quantidade de cursos e profissionais. Apesar disso, Cabedelo, município paraibano com apenas um curso de Odontologia, sendo este na rede privada, e 126 CDs em atividade, tem o maior PIB per capita do estado (R$ 42.556,16). O PIB per capita parece ser responsável pela distribuição de CDs nos municípios com cursos de graduação em Odontologia, no entanto, fatores como qualidade de vida, mercado de trabalho e saúde, tendem a exercerforte influência na distribuição destes profissionais (AU).

This study aimed at relating the distribution of Dentistry courses, number of dental surgeons (DS) and GDP per capitain municipalities of the state of Paraíbawith undergraduate courses in Dentistry. This is a descriptive cross-sectional study using secondary data from the Brazilian Federal Council of Dentistry (CFO), the Brazilian Institute of Geography and Statistics (IBGE) and the National Registry of HigherEducation Courses and Institutions. All data used in this study is publicly accessible. The state has 16 undergraduate courses in Dentistry, distributed in 6 municipalities: Araruna (1; 6.25%), Cabedelo (1; 6.25%), Cajazeiras (2; 12.50%), Campina Grande (6; 37.50%), João Pessoa (4; 25.00%) and Ducks (2; 12.50%). The municipalities with the highest GDP per capita, such as João Pessoa (R$ 24,319.82) and Campina Grande (R$ 21,077.30), also had a higher number of DS, with a positive correlation between the values of GDPper capita of each municipality and the number of courses and professionals. Besides, Cabedelo, a municipality in Paraíbawith only one Dentistry course, which is in the private network, and 126 active DS, has the highest GDPper capita in the state (R$ 42,556.16) (table 2). According to the results presented in this study, GDP per capita seems to be responsible for the distribution of SD in municipalities with undergraduate courses in Dentistry. However, factors such as quality of life, labor market and health tend to strongly influence the distribution of these professionals (AU).

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BACKGROUND: To evaluate the tooth enamel surface morphology after the action of 35% hydrogen peroxide with and without LED activation. MATERIAL AND METHODS: 70 bovine incisors with an enamel surface of 4x4x3 mm were used, prepared for reading superficial microhardness and roughness. Specimens were randomly distributed and divided into 7 experimental groups (n = 10); G1 = artificial saliva; G2 = 35% HP - 2 sessions (3x15´); G3 = Phosphoric Acid + 35% HP - 3 sessions (3x15´); G4 = 35% HP - 2 sessions (3x15´) + blue LED; G5 = 35% HP - 2 sessions (3x15´) + green LED; G6 = 35% HP - 2 sessions (3x20´) + violet LED; G7 = Violet LED - 2 sessions (3x20´). The results were analyzed by the Anova, Wilcoxon, Dunnett and Tukey tests (α = 0.05). RESULTS: The G4 group showed a greater change in microhardness. Regarding roughness, the biggest mean difference between groups occurred in G2, G5 and G7. Optical microscopy showed a smooth enamel surface in groups G2, G5 and G7. CONCLUSIONS: Changes in the enamel surface were observed in relation to microhardness, but without significant changes in roughness, where the LED (green and violet) resulted in a smooth surface. Key words:Tooth whitening, superficial morphology, light, photoradiatio.

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BACKGROUND: Dentin hypersensitivity (DH) is defined as an exaggerated sensitivity of vital dentin exposed to thermal, chemical and tactile stimuli. This study aimed to evaluate, through a literature review, the applicability of high- and low-intensity lasers in the treatment of DH for the past 10 years, as well as its therapeutic potential. MATERIAL AND METHODS: The electronic databases MEDLINE/PubMed and LILACS were searched using the descriptors ("Dentin Sensitivity" OR "Dentin Hypersensitivity") AND ("Low-Level Therapy" OR Laser), for articles published between 2010 and 2020. Only randomized clinical trials with full-text and full case resolution were included. RESULTS: We found 187 articles in total, among which 61 were pre-selected and 10 included in this literature review. CONCLUSIONS: Considering the found results and their possible limitations, high- and low-intensity lasers, associated or not with other therapies, have demonstrated beneficial effects in the treatment of DH, being considered a promising, safe, easy, and effective field of research, reducing pain sensitivity and preserving pulp vitality. Key words:Dentin sensitivity, dentistry, laser.

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Oral paresthesia is a localized condition of sensory abnormality that occurs in the presence of injury in one of the nerves in the region after certain dental procedures. The aim of this study was to present a case report of a patient who received low-level laser therapy as treatment for inferior alveolar nerve paresthesia due to mandibular third molar extraction surgery. A 25-year-old female patient reported lack of sensitivity for 6 months in various regions of the bucomaxillofacial complex after surgery. Laser therapy (808 ± 10nm, 100 mW, 3J per point and 30 seconds per point) was indicated twice a week. The degree of sensitivity was evaluated using a Visual Analog Scale (VAS) and with the aid of a microbrush. Prior to laser therapy, the patient reported VAS = 10, i.e., total lack of sensitivity. After 72 hours of the first session, the patient reported improvement of sensitivity in the chin (VAS = 5) and oral regions (VAS = 5), reporting recovery of sensitivity and that the area of paresthesia decreased. After 8 sessions, the patient reported total recovery of sensitivity in the chin, oral and gum regions (VAS = 0), with paresthesia being limited only to the left lower lip region and below it. After 26 sessions, the patient reported recovery of sensitivity in all affected regions (VAS = 0), with positive responses to the brush touch. Within the parameters used, laser therapy was effective in the treatment of inferior alveolar nerve paresthesia after third molar tooth extraction. Key words:Lasers, paresthesia, oral surgery, low-level laser therapy.

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The aim of this study was to evaluate the photobiomodulation of red and green lights in the repair process of third-degree skin burns in rats through clinicopathological and immunohistochemical parameters. Sixty male Wistar rats were divided into three groups: control (CTRL) (n = 20), red LED (RED) (n = 20), and green LED (GREEN) (n = 20), with subgroups (n = 5) for each time of euthanasia (7, 14, 21, and 28 days). Daily applications in RED (λ630 ± 10 nm, 300 mW) and GREEN groups (λ520 ± 30 nm, 180 mW) were performed at four points of the wound (total 36 J/cm2 in RED and 240 J/cm2 in GREEN). After euthanasia, the wound retraction index (WRI) was evaluated. In histological sections, the re-epithelialization degree, the angiogenic index (AI), and the amount of myofibroblasts in wounds were analyzed. At 14 and 21 days, the RED group induced higher re-epithelialization and WRI compared to CTRL (p > 0.05) and GREEN groups (p < 0.05). At 7 and 14 days, greater AI were observed in the GREEN group, with significant difference in relation to CTRL group at 7 days (p < 0.05). At 21 and 28 days, a trend was observed for greater amount of myofibroblasts in the GREEN group, with significant difference in relation to CTRL group at 21 days (p < 0.05). The results suggest greater potential of the green light to stimulate angiogenesis in the initial periods and myofibroblastic differentiation in the final periods of the repair of third-degree skin burns. Red light may stimulate further re-epithelialization and wound retraction, especially in advanced repair phases.

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The aim of this study was to investigate the Brazilian scientific production about acupuncture in dentistry, outlining the profile of the works about the subject presented at the Meetings of the Brazilian Society of Dental Research (SBPqO). It was a cross-sectional study, with a quantitative approach, based on secondary data. An analysis of all abstracts presented in the last ten SBPqO Meetings (2009-2018) published in the annals of the event was carried out. For the research the location of the term "acupuntura" or "acupuncture" among the abstracts was realized and the following information was collected: type of institution that carried out the research (public or private), Brazilian region where it was realized, area or specialty of dentistry and whether it involved humans or animals. Of the 26,514 dental research abstracts published in the annals, only 27 papers were experimental studies or systematic reviews about the subject. Of the total, 23 (85.2%) were developed in public institutions, 15 (55.6%) did not receive financial support 20 (74.1%) were carried out in humans and 13 (48.2%) were developed in the Southeast region. Regarding the dental specialty, the majority (70.4%) investigated acupuncture in "Temporomandibular Dysfunction and Orofacial Pain". Therefore, it can be concluded that few acupuncture studies in dentistry have been developed in the last ten years in Brazil, according to the papers presented at the SBPqO Meetings. Thus, it is suggested that research on the subject be carried out and widely disseminated between the academic and professional milieu. (AU)

O objetivo desse estudo foi investigar a produção científica brasileira sobre a acupuntura na odontologia, traçando o perfil dos trabalhos sobre a temática apresentados nas Reuniões da Sociedade Brasileira de Pesquisa Odontológica (SBPqO). Tratou-se de um estudo transversal, com abordagem quantitativa, a partir de dados secundários. Realizou-se uma análise de todos os resumos apresentados nas últimas dez Reuniões da SBPqO (2009-2018) publicados nos anais do evento. Para pesquisa procedeu-se a localização do termo "acupuntura" ou "acupuncture" entre os resumos e foram colhidas as seguintes informações: tipo de instituição que realizou a pesquisa (pública ou privada), região rasileira onde foi realizada, recebimento de auxílio financeiro, área ou especialidade da odontologia e se envolvia humanos ou animais. Dos 26.514 resumos de pesquisa odontológica publicados em anais, apenas 27 trabalhos tratavam de estudos experimentais ou revisões sistemáticas sobre a temática. Do total, 23 (85,2%) foram desenvolvidos em instituições públicas, 15 (55,6%) não receberam auxílio financeiro, 20 (74,1%) foram realizados em humanos e 13 (48,2%) desenvolvidos na região Sudeste do Brasil. Com relação a especialidade odontológica, a maioria (70,4%) pesquisou sobre a acupuntura na "Disfunção Temporomandibular e Dor Orofacial". Os achados do presente estudo indicam que poucas pesquisas abordando a acupuntura na odontologia foram desenvolvidas nos últimos dez anos no Brasil, de acordo com os trabalhos apresentados nas Reuniões da SBPqO. Diante disso, sugere-se que pesquisas sobre o tema sejam realizadas e amplamente divulgadas entre o meio acadêmico e profissionais. (AU)

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Antimicrobial Photodynamic Therapy (aPDT) is a promising approach with several clinical applications, including the treatment of periodontal diseases, by acting as an adjuvant to the conventional treatment of periodontal disease by allowing reduction of periodontopathogens, with no systemic side effects and minimal possibilities of bacterial resistance. Objective: To verify, through the scientific literature, the effectiveness of Antimicrobial Photodynamic Therapy associated with conventional periodontal treatment. Methodology: The literature review was conducted in the MEDLINE databases - PubMed, Scopus and Web of Science. The articles were selected through the analysis of titles and abstracts published in the period from 2007 to 2018. Selected articles were published in their entirety and with free or controlled access, of the type clinical trial on the subject, without restriction of languages. The terms used were: "Periodontal diseases"; "Chronic Periodontitis" and "Photochemotherapy." Results: 84 articles were found, and 20 clinical trials that met the inclusion criteria were analyzed. There were different clinical protocols for the association of aPDT with the conventional treatment of periodontal disease. a number of different clinical outcomes were found for each of the proposed clinical protocols. Conclusion: Considering the clinical trials investigated, conflicting results regarding the efficacy of aPTD as an adjuvant treatment of the conventional treatment of periodontal disease are observed. and lack of standardization of clinical parameters and protocols. (AU)

A terapia fotodinâmica antimicrobiana (aPDT) é uma abordagem promissora com várias aplicações clínicas, incluindo o tratamento das doenças periodontais, ao atuar como um adjuvante ao tratamento convencional da doença periodontal por permitir redução de periodontopatógenos, com ausência de efeitos sistêmicos colaterais e mínimas possibilidades de resistência bacteriana. O objetivo deste estudo é verificar, por meio da literatura científica, a eficácia da terapia fotodinâmica antimicrobiana associada ao tratamento periodontal convencional. A revisão de literatura foi conduzida nas bases de dados MEDLINE ­ PubMed, Scopus e Web of Science. Os artigos foram selecionados através da análise de títulos e de resumos publicados no período de 2007 a 2018. Foram selecionados artigos publicados na íntegra e com acesso livre e gratuito, ou controlado, do tipo ensaio clínico sobre o tema, sem restrição de idiomas. Os termos utilizados foram: Periodontal diseases; Chronic Periodontitis e Photochemotherapy. Foram encontrados 84 artigos, e 20 ensaios clínicos que atenderam os critérios de inclusão, foram analisados. Observou-se diferentes protocolos clínicos para a associação da aPDT com o tratamento convencional da doença periodontal. Também foram encontrados diferentes desfechos clínicos para cada um dos protocolos clínicos propostos. Conclusão: Considerando os ensaios clínicos pesquisados, observa-se resultados conflitantes frente à eficácia da aPDT como tratamento adjuvante do tratamento convencional da doença periodontal. Observa-se, ainda, uma produção literária escassa e a falta de uma padronização dos parâmetros e dos protocolos clínicos. (AU)

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Introdução: A endodontia é uma especialidade odontológica que visa promover a saúde dentária por meio da eliminação de micro-organismos capazes de causar agressões pulpares. A terapia fotodinâmica antimicrobiana, apresenta-se como uma alternativa coadjuvante ao tratamento endodôntico convencional para eliminação dos micro-organismos resistentes ao preparo-químico-mecânico. Objetivo: Explorar a literatura dando enfoque ao mecanismo de ação e aplicabilidade da aPDT na eliminação do Enterococcus faecalis. Material e método: Realizou-se uma revisão de literatura conduzida através do acesso às bases de dados eletrônicos Medline/Pubmed e Scielo utilizando isoladamente ou em associação as palavras-chaves "Photodynamic Therapy", "Enterococcus faecalis" e "Endodontic", no período de 2007 a 2017, totalizando 392 artigos. Resultados: A eliminação de forma eficaz de bactérias, Enterococcus faecalis, são vantagens atribuídas à terapia fotodinâmica, no entanto, a literatura evidencia a necessidade de utilizá-la associada a outras formas de tratamento. Conclusão: É necessária a padronização dos protocolos para que se obtenha dados mais esclarecedores sobre a eficácia da terapia fotodinâmica na eliminação do Enterococcus faecalis(AU)

Introduction: Endodontics is a dental specialty that aims to promote dental health by eliminating microorganisms capable of causing pulpal aggressions. Photodynamic antimicrobial therapy is an alternative to conventional endodontic treatment for the elimination of microorganisms resistant to chemical preparation. Objective: To explore the literature focusing on the mechanism of action and applicability of aPDT in the elimination of Enterococcus faecalis. Material and method: A literature review was conducted through access to the Medline / Pubmed and Scielo electronic databases using the keywords "Photodynamic Therapy", "Enterococcus faecalis" and "Endodontic". Results: The effective elimination of bacteria, Enterococcus faecalis, are advantages attributed to photodynamic therapy, however, the literature evidences the need to use it associated with other forms of treatment. Conclusion: Standardization of protocols is necessary to obtain more clarifying data on the efficacy of photodynamic therapy in the elimination of Enterococcus faecalis(AU)

Introducción: La endodoncia es una especialidad odontológica que busca promover la salud dental a través de la eliminación de microorganismos capaces de causar agresiones pulpares. La terapia fotodinámica antimicrobiana, se presenta como una alternativa coadyuvante al tratamiento endodóntico convencional para la eliminación de los microorganismos resistentes al preparado-químico-mecánico. Objetivo: Explorar la literatura centrándose en el mecanismo de acción y aplicabilidad de la aPDT en la eliminación del Enterococcus faecalis. Material y método: Se realizó una revisión de literatura conducida a través del acceso a las bases de datos electrónicos Medline / Pubmed y Scielo utilizando aisladamente o en combinación las palabras clave "Photodynamic Therapy", "Enterococcus faecalis" y "Endodontic". Resultados: La eliminación eficaz de bacterias, Enterococcus faecalis, son ventajas atribuidas a la terapia fotodinámica, sin embargo, la literatura evidencia la necesidad de utilizarla asociada a otras formas de tratamiento. Conclusión: Es necesaria la estandarización de los protocolos para que se obtengan datos más claros sobre la eficacia de la terapia fotodinámica en la eliminación del Enterococcus faecalis(AU)

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