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OBJETIVO: Discutir como se estabelece a indicação de tecnologias relacionais off-line e on-line como recurso de cuidado a Pessoas Vivendo com HIV/Aids (PVHA) por psicólogas/os atuantes em serviços especializados. MÉTODO: Trata-se de uma pesquisa de abordagem qualitativa e exploratória. Utilizamos a perspectiva da psicologia social construcionista, além das noções de tecnologias dura, leve-dura e leve e seu encontro com a perspectiva de tecnologias (materiais e não materiais) como mediadoras inventivas. Realizamos entrevistas semiestruturadas e submetemos os dados à análise categorial temática. RESULTADOS: Foram elaboradas duas categorias: tecnologias relacionais off-line e on-line. Tratam-se dos sentidos construídos em torno de estratégias para o cuidado de PVHA, que não são típicas da clínica psicológica clássica. CONCLUSÃO: Concluímos que o uso de tecnologias relacionais off-line e on-line no acompanhamento de PVHA sugere uma ampliação do repertório profissional das/dos psicólogas/os que trabalham em serviços especializados em HIV/Aids, porém, isso não demonstrou ocorrer de forma tão articulada no campo de atuação psicológica, em comparação às práticas psicológicas clássicas.

OBJECTIVE: To discuss how offline and online relational technologies are recommended as a care resource for People Living with HIV/Aids (PLWHA) by psychologists working in specialized services. METHOD: This is research with a qualitative and exploratory approach. We use the perspective of constructionist social psychology, in addition to the notions of hard, soft-hard and soft technologies and their encounter with the perspective of technologies (material and non-material) as inventive mediators. We carried out semi-structured interviews and submitted the data to thematic categorical analysis. RESULTS: Two categories were created: offline and online relational technologies. These are the meanings constructed around strategies for caring for PLWHA, which are not typical of classical psychological clinics. CONCLUSION: We conclude that the use of offline and online relational technologies in monitoring PLWHA suggests an expansion of the professional repertoire of psychologists working in specialized HIV/AIDS services, however, this has not been demonstrated to occur in a so articulated, in the field of psychological action, in comparison to classical psychological practices.

OBJETIVO: Discutir cómo las tecnologías relacionales offline y online son recomendadas como recurso de atención a las Personas que Viven con VIH/SIDA (PVVS) por parte de psicólogos que trabajan en servicios especializados. MÉTODO: Se trata de una investigación con un enfoque cualitativo y exploratorio. Utilizamos la perspectiva de la psicología social construccionista, además de las nociones de tecnologías duras, blandas-duras y blandas y su encuentro con la perspectiva de las tecnologías (materiales y no materiales) como mediadoras inventivas. Realizamos entrevistas semiestructuradas y sometimos los datos a análisis temático categórico. RESULTADOS: Se crearon dos categorías: tecnologías relacionales en línea y fuera de línea. Estos son los significados construidos en torno a estrategias de atención a las PVVS, que no son propias de las clínicas psicológicas clásicas. CONCLUSIÓN: Concluimos que el uso de tecnologías relacionales en línea y fuera de línea en el seguimiento de las PVVS sugiere una expansión del repertorio profesional de los psicólogos que trabajan en servicios especializados en VIH/SIDA, sin embargo, no se ha demostrado que esto ocurra de manera tan articulada en el campo de acción psicológica, en comparación con las prácticas psicológicas clásicas.

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Bone morphogenetic protein (BMP) and platelet-derived growth factor (PDGF) are known to regulate/stimulate osteogenesis, playing vital roles in bone homeostasis, rendering them strong candidates for osteoporosis treatment. We evaluated the effects of recombinant human BMP-7 (rhBMP7) and PDGF-BB (rhPDGF-BB) in an oophorectomy-induced osteoporosis rat model. Forty Sprague Dawley rats underwent oophorectomy surgery; treatments commenced on the 100th day post-surgery when all animals exhibited signs of osteoporosis. These peptide growth factors were administered intraocularly (iv) once or twice a week and the animals were monitored for a total of five weeks. Two weeks after the conclusion of the treatments, the animals were euthanized and tissues were collected for assessment of alkaline phosphatase, X-ray, micro-CT, and histology. The results indicate that the most promising treatments were 20 µg/kg rhPDGF-BB + 30 µg/kg rhBMP-7 twice a week and 30 µg/kg BMP-7 twice a week, showing significant increases of 15% (p < 0.05) and 13% (p < 0.05) in bone volume fraction and 21% (p < 0.05) and 23% (p < 0.05) in trabecular number, respectively. In conclusion, rhPDGF-BB and rhBMP-7 have demonstrated the ability to increase bone volume and density in this osteoporotic animal model, establishing them as potential candidates for osteoporosis treatment.

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The warty dyskeratoma is a neoplasm of follicular origin, with uncommon incidence in veterinary medicine, and benign biological behavior. An excisional biopsy sample was received from a dog, female, Shih Tzu, 12 years old, from the left axillary region. Grossly, after section, green and friable multifocal areas were identified, streaked by solid white areas. Microscopically, the analysis revealed multifocal cystic structures, lined by stratified epithelium, with basal area including villous epithelial projections, toward the dermis, and the luminal region featured acantholysis and dyskeratosis, as well as parakeratosis. Those findings were compatible with a warty dyskeratoma affecting multiple hair follicles, thus being the first case report in veterinary medicine with such this unique pattern. Up to now, the literature encompassed only human medicine. This report, besides collaborating to the description of a rare presentation of an uncommon neoplasm, also contributes with new information found for epidemiological studies of this tumor.(AU)

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BACKGROUND: Stroke is one of the main causes of mortality worldwide. Nonetheless, there are still risk factors that have not been fully elucidated, such as chronic insomnia disorder. OBJECTIVE: To evaluate the association between chronic insomnia disorder and the risk of stroke in adults, through a systematic review. METHODS: Multiple studies available in the Embase, Lilacs, and Medline platforms were evaluated in English, Spanish, French, and Portuguese. The selection of papers was restricted to those that had investigated the association between chronic insomnia disorder and stroke in adults, regardless of gender or nationality, without a previous history of stroke. The data was extracted with the Cochrane Effective Practice and Organization of Care (EPOC) form. The risk of bias was evaluated by the EPOC Risk of bias tool. RESULTS: A total of 138 articles were identified. After a detailed evaluation with the eligibility criteria, four articles were included in the present systematic review. Three of them recognized the association between chronic insomnia disorder and stroke. The comparative analysis was limited, since the studies used distinct insomnia classifications. Regarding the risk of bias, the analysis displayed an important risk in the selection and allocation of participants, besides the use of own insomnia diagnosis criteria, disrespecting chronology and factors indicated by already established classifications. CONCLUSIONS: There is not enough data to determine that chronic insomnia disorder is a risk factor for stroke. The present study points out the existence of a possible relationship between insomnia disorder and stroke, suggesting that further studies adopt standardized criteria and instruments.

ANTECEDENTES: O acidente vascular cerebral (AVC) é uma das maiores causas de mortalidade do mundo. Ainda assim, existem fatores de risco não identificados, como o transtorno de insônia crônica. OBJETIVO: Avaliar a associação entre distúrbio crônico de insônia e o risco de AVC em adultos, por meio de uma revisão sistemática. MéTODOS: Foram avaliados estudos publicados em inglês, espanhol, francês e português, disponíveis nas plataformas Embase, Lilacs e Medline. Os estudos incluídos foram aqueles que investigaram a associação entre transtorno de insônia crônica e AVC em adultos, sem restrição de gênero ou de nacionalidade, sem história prévia de AVC. Os dados foram extraídos baseados no formulário da Cochrane Effective Practice and Organisation of Care (EPOC, na sigla em inglês). O risco de viés foi avaliado por meio da ferramenta EPOC Risk of bias tool. RESULTADOS: Foram identificados 138 artigos, entre os quais, após avaliação detalhada para os critérios de elegibilidade, 4 foram incluídos na revisão sistemática. Destes, três encontraram associação entre insônia e AVC. Contudo, a análise comparativa apresenta limitações, pois nenhum dos estudos utilizou uma classificação comum de insônia. Quanto à análise do risco de viés, os estudos demonstraram um importante risco de viés na seleção e na alocação de participantes, além de utilizarem critérios diagnósticos de insônia próprios, sem respeitar cronologia e fatores indicados por classificações já estabelecidas. CONCLUSõES: Não existem dados suficientes para determinar que o transtorno crônico de insônia se configura como fator de risco para AVC. A análise aponta para a existência de uma possível relação, sugerindo-se para estudos posteriores o uso de critérios e instrumentos padronizados.

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Abstract Background Stroke is one of the main causes of mortality worldwide. Nonetheless, there are still risk factors that have not been fully elucidated, such as chronic insomnia disorder. Objective To evaluate the association between chronic insomnia disorder and the risk of stroke in adults, through a systematic review. Methods Multiple studies available in the Embase, Lilacs, and Medline platforms were evaluated in English, Spanish, French, and Portuguese. The selection of papers was restricted to those that had investigated the association between chronic insomnia disorder and stroke in adults, regardless of gender or nationality, without a previous history of stroke. The data was extracted with the Cochrane Effective Practice and Organization of Care (EPOC) form. The risk of bias was evaluated by the EPOC Risk of bias tool. Results A total of 138 articles were identified. After a detailed evaluation with the eligibility criteria, four articles were included in the present systematic review. Three of them recognized the association between chronic insomnia disorder and stroke. The comparative analysis was limited, since the studies used distinct insomnia classifications. Regarding the risk of bias, the analysis displayed an important risk in the selection and allocation of participants, besides the use of own insomnia diagnosis criteria, disrespecting chronology and factors indicated by already established classifications. Conclusions There is not enough data to determine that chronic insomnia disorder is a risk factor for stroke. The present study points out the existence of a possible relationship between insomnia disorder and stroke, suggesting that further studies adopt standardized criteria and instruments.

Resumo Antecedentes O acidente vascular cerebral (AVC) é uma das maiores causas de mortalidade do mundo. Ainda assim, existem fatores de risco não identificados, como o transtorno de insônia crônica. Objetivo Avaliar a associação entre distúrbio crônico de insônia e o risco de AVC em adultos, por meio de uma revisão sistemática. Métodos Foram avaliados estudos publicados em inglês, espanhol, francês e português, disponíveis nas plataformas Embase, Lilacs e Medline. Os estudos incluídos foram aqueles que investigaram a associação entre transtorno de insônia crônica e AVC em adultos, sem restrição de gênero ou de nacionalidade, sem história prévia de AVC. Os dados foram extraídos baseados no formulário da Cochrane Effective Practice and Organisation of Care (EPOC, na sigla em inglês). O risco de viés foi avaliado por meio da ferramenta EPOC Risk of bias tool. Resultados Foram identificados 138 artigos, entre os quais, após avaliação detalhada para os critérios de elegibilidade, 4 foram incluídos na revisão sistemática. Destes, três encontraram associação entre insônia e AVC. Contudo, a análise comparativa apresenta limitações, pois nenhum dos estudos utilizou uma classificação comum de insônia. Quanto à análise do risco de viés, os estudos demonstraram um importante risco de viés na seleção e na alocação de participantes, além de utilizarem critérios diagnósticos de insônia próprios, sem respeitar cronologia e fatores indicados por classificações já estabelecidas. Conclusões Não existem dados suficientes para determinar que o transtorno crônico de insônia se configura como fator de risco para AVC. A análise aponta para a existência de uma possível relação, sugerindo-se para estudos posteriores o uso de critérios e instrumentos padronizados.

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The genus Dermocystidium infects a wide range of animals. The host infection often occurs through the ingestion of endospores. The diagnosis depends on wet mounts and histopathological analysis of the affected tissue. The aim of this study was to investigate the incidence of Dermocystidium sp. infection on the skin of farmed striped catfish (Pangasianodon hypophthalmus) from a fish farm located in Fortaleza, Ceará state, northeastern Brazil. From these observations, we determined that 100% of the analyzed animals were infected with Dermocystidium sp. The wet mount and histopathology of the fish lesions revealed spore-filled cysts between the dermis and epidermis, encapsulated by connective tissue. Owing to a lack of research on the parasite and its prevalence among different fish species in Brazil and the rest of the world, additional studies are required to understand their endemicity in fish farms of Brazil, and consequently develop better disease prevention methods and increase the overall productivity.

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BACKGROUND: SORTING BY TRANSPOSITIONS (SBT) is a classical problem in genome rearrangements. In 2012, SBT was proven to be [Formula: see text]-hard and the best approximation algorithm with a 1.375 ratio was proposed in 2006 by Elias and Hartman (EH algorithm). Their algorithm employs simplification, a technique used to transform an input permutation [Formula: see text] into a simple permutation [Formula: see text], presumably easier to handle with. The permutation [Formula: see text] is obtained by inserting new symbols into [Formula: see text] in a way that the lower bound of the transposition distance of [Formula: see text] is kept on [Formula: see text]. The simplification is guaranteed to keep the lower bound, not the transposition distance. A sequence of operations sorting [Formula: see text] can be mimicked to sort [Formula: see text]. RESULTS AND CONCLUSIONS: First, using an algebraic approach, we propose a new upper bound for the transposition distance, which holds for all [Formula: see text]. Next, motivated by a problem identified in the EH algorithm, which causes it, in scenarios involving how the input permutation is simplified, to require one extra transposition above the 1.375-approximation ratio, we propose a new approximation algorithm to solve SBT ensuring the 1.375-approximation ratio for all [Formula: see text]. We implemented our algorithm and EH's. Regarding the implementation of the EH algorithm, two other issues were identified and needed to be fixed. We tested both algorithms against all permutations of size n, [Formula: see text]. The results show that the EH algorithm exceeds the approximation ratio of 1.375 for permutations with a size greater than 7. The percentage of computed distances that are equal to transposition distance, computed by the implemented algorithms are also compared with others available in the literature. Finally, we investigate the performance of both implementations on longer permutations of maximum length 500. From the experiments, we conclude that maximum and the average distances computed by our algorithm are a little better than the ones computed by the EH algorithm and the running times of both algorithms are similar, despite the time complexity of our algorithm being higher.

RESUMO

The genus Dermocystidium infects a wide range of animals. The host infection often occurs through the ingestion of endospores. The diagnosis depends on wet mounts and histopathological analysis of the affected tissue. The aim of this study was to investigate the incidence of Dermocystidium sp. infection on the skin of farmed striped catfish (Pangasianodon hypophthalmus) from a fish farm located in Fortaleza, Ceará state, northeastern Brazil. From these observations, we determined that 100% of the analyzed animals were infected with Dermocystidium sp. The wet mount and histopathology of the fish lesions revealed spore-filled cysts between the dermis and epidermis, encapsulated by connective tissue. Owing to a lack of research on the parasite and its prevalence among different fish species in Brazil and the rest of the world, additional studies are required to understand their endemicity in fish farms of Brazil, and consequently develop better disease prevention methods and increase the overall productivity.(AU)

O gênero Dermocystidium infecta uma ampla variedade de espécies de animais, e o hospedeiro pode se infectar pela ingestão de endósporos. O diagnóstico depende de montagem em lâmina a fresco e análise histopatológica dos tecidos afetados. O objetivo deste estudo foi relatar infecção por Dermocystidium na pele do bagre listrado (P. hypophthalmus), cultivado em piscicultura do estado do Ceará, nordeste do Brasil. Foi detectado que 100% dos animais analisados estavam infectados por Dermocystidium sp. A montagem em lâminas a fresco e histopatologia das lesões mostrou cistos repletos de esporos entre a derme e a epiderme, encapsulados por tecidos conectivos. Devido às escassas pesquisas sobre esse parasito, em diferentes espécies de peixes no Brasil e no mundo, estudos adicionais são necessários para entender a endemicidade em diferentes pisciculturas do Brasil, consequentemente, melhorando os métodos de prevenção da doença e aumentando a produção e a produtividade.(AU)

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BACKGROUND: In the adult population, the work environment and physical fitness levels are directly related to the onset of musculoskeletal pain, repetitive strain injuries, and decreased blood circulation. Although low levels of muscle strength and flexibility may lead to a higher prevalence of pain, specific anatomic regions are poorly addressed. OBJECTIVE: To investigate the prevalence of musculoskeletal pain and the association between strength or flexibility and pain in university staff. METHODS: The sample was composed of 110 members of staff from a university in Guarapuava-PR. Body mass and height values were obtained, from which the BMI was calculated. The pain evaluation was performed by means of a questionnaire, analyzing the intensity, frequency, and anatomical region. The subjects were then submitted to strength (right and left hand grip, lumbar traction, lower limb traction) and flexibility tests (sit and reach test). RESULTS: The anatomical region with the highest prevalence of pain was the lumbar region (43.4%). When the association between the presence of pain and flexibility was performed, only the lumbar traction presented significant results, with the weakest group demonstrating pain (OR: 3.47 [1.27 - 9.49]). CONCLUSION: The results demonstrate that low levels of strength in the lumbar region are associated with the presence of painful symptomatology.

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Objetivo: conhecer a perceção dos efeitos da hidratação em idosos durante o exercício aeróbico. Método: pesquisa descritiva observacional, com delineamento transversal. Entre os meses de julho e setembro de 2018. Foram realizadas as aferições de massa corpórea, porcentagem de líquidos e gordura no corpo antes e após a atividade física em oito idosos. Aplicou-se análise estatistica descritiva. Resultados: a maioria dos idosos participantes não possuem preocupação com a ingesta hídrica tanto no pré treino quanto no pós-treino. Outro achado nesse estudo é que a maioria também tem o habito de ingerir líquidos somente diante da sensação de "garganta seca". Ocorreu redução de gordura corporal e aumento de percentual hídrico comparado aos idosos que não se hidrataram. Conclusão: o estudo mostrou que os idosos não possuem orientação adequada para a hidratação antes e durante o exercício, mesmo sendo acompanhados por educador físico. Ficou evidente que ocorrem alterações fisiológicas positivas entre aqueles que se hidratam tanto antes como após o exercício aeróbico.

Objective: to know the perception of hydration effects in the elderly during aerobic exercise. Method: a descriptive observational field research with crosssectional design was performed. Between July and September 2018, body mass, body fluid and body fat percentage were measured before and after exercise in eight elderly. Descriptive statistical analysis was applied. Results: most elderly participants have no concern with the fluid intake in the pre-training as posttraining. Another finding in this study is that most also have the habit of ingesting fluids only when feeling "dry throat". There was reduction of body fat and increase of water percentage compared to the elderly who did not hydrate. Conclusion: the study showed that the elderly do not have adequate orientation for hydration before and during exercise, even when accompanied by a physical educator. It was evident that positive physiological changes occur among those who hydrate both before and after aerobic exercise.

Objetivo: conocer la percepción de los efectos de hidratación en los ancianos durante el ejercicio aeróbico. Método: se realizó una investigación de campo de observación descriptiva con diseño transversal. Entre julio y septiembre de 2018, el porcentaje de masa corporal, fluidos corporales y grasa corporal se midió antes y después del ejercicio en ocho ancianos. Se aplicó análisis estadístico descriptivo. Resultados: La mayoría de los participantes de edad avanzada no tienen ninguna preocupación con las preocupaciones sobre el consumo de agua después del entrenamiento. Otro hallazgo en este estudio es que la mayoría también tiene el hábito de ingerir líquidos solo cuando siente "garganta seca". Hubo una reducción de la grasa corporal y un aumento del porcentaje de agua en comparación con los ancianos que no se hidrataron. Conclusión: el estudio mostró que los ancianos no tienen una orientación adecuada para la hidratación antes y durante el ejercicio, incluso si están acompañados por un educador físico. Era evidente que se producen cambios fisiológicos positivos entre quienes hidratan antes y después del ejercicio aeróbico.

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Objetivo: comparar a avaliação antropométrica e fatores motivacionais de praticantes de hidroginástica e caminhada. Método: pesquisa quase experimental, sem grupo controle e de cunho quantitativo, realizada em Guarapuava, Paraná. Analisou-se o IMC, porcentagem de gordura, circunferências, relação cintura quadril, teste de força com preensão manual e teste de flexibilidade com o banco de wells. Aplicou-se também, o questionário de motivação (IMPRAF-54). Após a coleta de dados, foi realizada a análise estatística através do teste T, comparando as medidas entre os grupos. Resultados: foi observado que a motivação mais prevalente para praticar as atividades físicas foi o fator saúde. Na avaliação antropométrica, as praticantes de hidroginástica possuíam índices superiores. Nos testes de força e flexibilidade as praticantes de hidroginástica apresentaram maior força em membros superiores, enquanto que as praticantes de caminhada maios flexibilidade em membros inferiores. Conclusão: a hidroginástica possui benefícios extras em comparação à caminhada e a motivação das participantes para praticar essas atividades físicas indica sua preocupação com a condição e qualidade de vida.(AU)

Objective: to compare the anthropometric evaluation and motivational factors of water aerobics and walking practitioners. Method: almost experimental research, with no control group and quantitative, performed in Guarapuava, Paraná. The BMI, fat percentage, circumference, waist hip ratio, strength test with manual grip and flexibility test with the wells bench were analyzed. The motivation questionnaire (IMPRAF-54) was also applied. After the data collection, the statistical analysis was performed through the T test, comparing the measurements between the groups. Results: it was observed that the most prevalent motivation to practice physical activities was the health factor. In the anthropometric evaluation, the hydrogymnastics practitioners had higher indices. In the tests of strength and flexibility, water aerobics practitioners showed greater strength in the upper limbs, whereas those who practice walking have greater flexibility in the lower limbs. Conclusion: water aerobics has extra benefits compared to walking and the motivation of the participants to practice these physical activities indicates their concern with the condition and quality of life.(AU)

Objetivo: comparar la evaluación antropométrica y factores motivacionales de practicantes de hidroginástica y caminar. Método: investigación casi experimental, sin grupo control y de cuño cuantitativo, realizada en Guarapuava, Paraná. Se analizó el IMC, porcentaje de grasa, circunferencias, relación cintura cadera, prueba de fuerza con asimiento manual y prueba de flexibilidad con el banco de wells. Se aplicó también el cuestionario de motivación (IMPRAF-54). Después de la recolección de datos, se realizó el análisis estadístico a través de la prueba T, comparando las medidas entre los grupos. Después de la recolección de datos, se realizó el análisis estadístico a través de la prueba T, comparando las medidas entre los grupos. Resultados: se observó que la motivación más prevalente para practicar las actividades físicas fue el factor salud. En la evaluación antropométrica, las practicantes de hidroginástica poseían índices superiores. En las pruebas de fuerza y flexibilidad las practicantes de hidroginástica presentaron mayor fuerza en miembros superiores, mientras que las practicantes de caminata maios flexibilidad en miembros inferiores. Conclusión: la hidroginástica posee beneficios extras en comparación con la caminata y la motivación de las participantes para practicar esas actividades físicas indica la preocupación por la condición y calidad de vida.(AU)

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The aim of the study was to develop and validate a questionnaire that evaluated the degree of satisfaction of the users attending School Clinics of Physiotherapy and to evaluate the level of satisfaction of the users of the School Clinic of Anhanguera University of Taubaté. The structuring of the questionnaire was based on previous studies with similar themes, for this a survey was carried out in the databases Lilacs, PubMed, SciELO, SPORTDiscus, MEDLINE e Ebsco, with the descriptors "physiotherapy", "satisfaction", "school clinic" and "questionnaire", after this process the questionnaire with attention to School Clinics was developed. The questionnaire was subjected to a qualitative evaluation of its questions, carried out by 20 professors. Subsequently, for the validation of the construct 3 PHD professors evaluated clarity, coherence and concordance of each question, and then the Construct Validity Coefficient was applied. The questionnaire underwent a pilot study with 30 users for cultural adequacy of its issues. A reliability by Cronbach's alpha coefficient obtained was 0.98, and the Construct Validity Coefficient was 0.93, which expresses the internal consistency and satisfactory validity of the questionnaire according to psychometric standards. The users of the Physiotherapy School Clinic of the Anhanguera of Taubaté were satisfied with the care services, physical environment and access, presenting an average of 4.34 of total scores. This study developed and satisfactorily validated a questionnaire that evaluate the satisfaction index of users of the School Clinic of Physiotherapy, beside this there was also a high satisfaction index of users of the School Clinic of Physiotherapy of Anhanguera University of Taubaté. (AU)

O objetivo do estudo foi desenvolver e validar um questionário que avalie o grau de satisfação dos usuários atendidos em Clínicas-escola de Fisioterapia, e verificar o nível de satisfação dos usuários da Clínica-escola da Faculdade Anhanguera de Taubaté. A estruturação do questionário se baseou em estudos anteriores com temas similares, para isto realizou-se um levantamento nas bases de dados Lilacs, PubMed, SciELO, SPORTDiscus, Medline e Ebsco, com os descritores "physiotherapy", "satisfaction", "school clinic" e "questionnaire", após esse processo o questionário com atenção a Clínicas-escola foi desenvolvido. O questionário passou por uma avaliação qualitativa de suas questões, realizada por 20 docentes. Posteriormente, para a validação do construto, 3 docentes doutores avaliaram as vertentes clareza, coerência e concordância de cada questão, e então aplicou-se o Coeficiente de Validade de Construto. O questionário passou por um estudo piloto com 30 usuários para adequação cultural de suas questões. A confiabilidade, por meio do Coeficiente alfa de Cronbach obtida foi de 0,98, e o Coeficiente de Validade de Construto foi de 0,93, o que expressa elevada consistência interna e satisfatória validade do questionário segundo padrões psicométricos. Os usuários da Clínica-escola de Fisioterapia da Anhanguera de Taubaté mostraram-se satisfeitos com o atendimento, ambiente físico e acesso, apresentando média de 4,34 de escore total. Este estudo conseguiu desenvolver e validar de forma satisfatória um questionário que avalia o índice de satisfação de usuários de Clínicas-escola de Fisioterapia. Além disto, verificou-se também que existe alto índice de satisfação dos usuários da Clínica-escola de Fisioterapia da Faculdade Anhanguera de Taubaté. (AU)

RESUMO

INTRODUÇÃO: O sedentarismo é um fator de risco para o desenvolvimento diversas doenças, enquanto o estilo de vida fisicamente ativo e a aptidão física podem atuar na promoção e na manutenção da saúde. OBJETIVO: Verificar o nível de atividade física e compará-lo com indicadores de força muscular e estrutura morfológica em agentes universitários. MÉTODO: Participaram do estudo 44 agentes universitários, dos quais foram obtidas as medidas de massa corporal (MC) e de estatura, para posterior cálculo do Índice de Massa Corporal. A análise do nível de atividade física foi realizada pelo Questionário Internacional de Atividade Física (IPAQ). Em seguida, os agentes universitários foram submetidos a quatro testes de força: preensão manual direita (PMD) e esquerda (PME), tração lombar (TL) e tração de membros inferiores (TMI). A força muscular relativa (%FM) foi estimada pela divisão da força muscular absoluta (FMA=PMD+PME+TL+TMI) pela MC. RESULTADOS: O grupo insuficientemente ativo apresentou significativamente maior MC, maior tempo de comportamento sedentário nos fins de semana e menores indicadores de TL, TMI, FMA e %FM comparado aos fisicamente ativos. CONCLUSÃO: A inatividade física foi associada a menores indicadores de força muscular e maior MC em agentes universitários, sugerindo riscos para a saúde inerentes ao comportamento sedentário.

BACKGROUND: Sedentary behavior is a risk factor for several diseases, while physically active lifestyles and physical fitness contribute to the promotion and maintenance of health. OBJECTIVE: To establish the level of physical activity of university administrative employees and investigate its relationship with muscle strength indicators and morphological characteristics. METHODS: The sample comprised 44 university administrative employees. Data on body mass (BM) and height were collected to calculate the body mass index. The participants' level of physical activity was established based on the International Physical Activity Questionnaire (IPAQ). The participants were subjected to four muscle strength tests: right hand grip (RHG), left hand grip (LHG), lumbar traction (LT) and lower limb traction (LLT). Relative muscle strength (%MS) was calculated dividing absolute muscle strength (AMS=RHG+LHG+LT+LLT) by BM. RESULTS: The insufficiently active participants exhibited significant higher BM, lower LT, LLT, AMS and %MS, and spent more time in sedentary activities on weekends. CONCLUSION: Physical inactivity was associated with poorer muscle strength indicators and higher BM among university administrative employees, pointing to harms inherent to sedentary behavior.

RESUMO

Ovulation synchronization protocols are well established in beef and dairy cows. However, the protocol response rate is around 70-90%. In beef cows, factors such as inadequate nutrition and calf presence negatively impact the response of progesterone (P4)/estradiol-based ovulation synchronization protocols by interfering with GnRH release and consequently reducing LH pulsatility and final follicular development. In dairy cows, protocols based on GnRH and prostaglandin (Ovsynch) are the most widely used in the world. However, the efficiency of Ovsynch is dependent on the presence of a large follicle at the time of administration of the first GnRH. In these ovulation synchronization protocols, pre-synchronization protocols (Prostaglandins, Double Ovsynch and P4synch) are usually attempted in an effort to increase responses. Thus, the objective of this review was to discuss pre-ovulation synchronization strategies (administration of injectable P4 or energetic/protein supplementation or pre-synchronization with intra-vaginal progesterone devices) aiming to increase the LH pulsatility in beef cows or induce the formation of a GnRH-responsive follicle at the beginning of the Ovsynch protocol in dairy cows.

RESUMO

BACKGROUND: Sedentary behavior is a risk factor for several diseases, while physically active lifestyles and physical fitness contribute to the promotion and maintenance of health. OBJECTIVE: To establish the level of physical activity of university administrative employees and investigate its relationship with muscle strength indicators and morphological characteristics. METHODS: The sample comprised 44 university administrative employees. Data on body mass (BM) and height were collected to calculate the body mass index. The participants' level of physical activity was established based on the International Physical Activity Questionnaire (IPAQ). The participants were subjected to four muscle strength tests: right hand grip (RHG), left hand grip (LHG), lumbar traction (LT) and lower limb traction (LLT). Relative muscle strength (%MS) was calculated dividing absolute muscle strength (AMS=RHG+LHG+LT+LLT) by BM. RESULTS: The insufficiently active participants exhibited significant higher BM, lower LT, LLT, AMS and %MS, and spent more time in sedentary activities on weekends. CONCLUSION: Physical inactivity was associated with poorer muscle strength indicators and higher BM among university administrative employees, pointing to harms inherent to sedentary behavior.

INTRODUÇÃO: O sedentarismo é um fator de risco para o desenvolvimento diversas doenças, enquanto o estilo de vida fisicamente ativo e a aptidão física podem atuar na promoção e na manutenção da saúde. OBJETIVO: Verificar o nível de atividade física e compará-lo com indicadores de força muscular e estrutura morfológica em agentes universitários. MÉTODO: Participaram do estudo 44 agentes universitários, dos quais foram coletados valores da massa corporal (MC) e de estatura, para posterior cálculo do Índice de Massa Corporal. A análise do nível de atividade física foi realizada pelo Questionário Internacional de Atividade Física (IPAQ). Em seguida, os agentes universitários foram submetidos a quatro testes de força: preensão manual direita (PMD) e esquerda (PME), tração lombar (TL) e tração de membros inferiores (TMI). A força muscular relativa (%FM) foi estimada pela divisão da força muscular absoluta (FMA=PMD+PME+TL+TMI) pela MC. RESULTADOS: O grupo insuficientemente ativo apresentou significativamente maior MC, maior tempo de comportamento sedentário nos fins de semana e menores indicadores de TL, TMI, FMA e %FM comparado aos fisicamente ativos. CONCLUSÃO: A inatividade física foi associada a menores indicadores de força muscular e maior MC em agentes universitários, sugerindo riscos para a saúde inerentes ao comportamento sedentário.

RESUMO

Ovulation synchronization protocols are well established in beef and dairy cows. However, the protocol response rate is around 70-90%. In beef cows, factors such as inadequate nutrition and calf presence negatively impact the response of progesterone (P4)/estradiol-based ovulation synchronization protocols by interfering with GnRH release and consequently reducing LH pulsatility and final follicular development. In dairy cows, protocols based on GnRH and prostaglandin (Ovsynch) are the most widely used in the world. However, the efficiency of Ovsynch is dependent on the presence of a large follicle at the time of administration of the first GnRH. In these ovulation synchronization protocols, pre-synchronization protocols (Prostaglandins, Double Ovsynch and P4synch) are usually attempted in an effort to increase responses. Thus, the objective of this review was to discuss pre-ovulation synchronization strategies (administration of injectable P4 or energetic/protein supplementation or presynchronization with intra-vaginal progesterone devices) aiming to increase the LH pulsatility in beef cows or induce the formation of a GnRH-responsive follicle at the beginning of the Ovsynch protocol in dairy cows.

Assuntos

RESUMO

Ovulation synchronization protocols are well established in beef and dairy cows. However, the protocol response rate is around 70-90%. In beef cows, factors such as inadequate nutrition and calf presence negatively impact the response of progesterone (P4)/estradiol-based ovulation synchronization protocols by interfering with GnRH release and consequently reducing LH pulsatility and final follicular development. In dairy cows, protocols based on GnRH and prostaglandin (Ovsynch) are the most widely used in the world. However, the efficiency of Ovsynch is dependent on the presence of a large follicle at the time of administration of the first GnRH. In these ovulation synchronization protocols, pre-synchronization protocols (Prostaglandins, Double Ovsynch and P4synch) are usually attempted in an effort to increase responses. Thus, the objective of this review was to discuss pre-ovulation synchronization strategies (administration of injectable P4 or energetic/protein supplementation or presynchronization with intra-vaginal progesterone devices) aiming to increase the LH pulsatility in beef cows or induce the formation of a GnRH-responsive follicle at the beginning of the Ovsynch protocol in dairy cows.(AU)

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Introduction: The overweight of school backpacks results in an increase of mechanical load in the locomotive apparatus of the students during the locomotion. Objective: Analyze and compare kinetic and kinematic temporal/spatial variables during gait and transport of backpacks with wheels (10% body weight of load) in schoolchildren aged 7 to 10 years. Methods: Ten healthy children (7.8 ± 1.6 years) participate in two experimental conditions, first condition involved the gait in the plane, and the second condition the backpack transport provided with wheels in the plane (10% body weight) occurred. Results: Soil reaction forces in force platform did not show any differences between the conditions. The similarities indicate that wheeled backpacks do not require time changes or application of forces to perform the task when compared to the unladen gait in the plane. The kinematics of the ankle, knee and pelvis remained unchanged. Conclusion: The use of 10% BW of load in the backpack during transport was not influenced gait.

Introdução: A sobrecarga em mochilas escolares pode resultar em aumento de carga mecânica sobre o aparelho locomotuvo de estudantes durante a marcha. Objetivo: Analisar e comparar as variáveis temporais/espaciais cinéticas e cinemáticas durante a marcha e o transporte de mochilas com rodas (10% peso corporal (PC)) em escolares de 7 a 10 anos. Métodos: Dez crianças, saudáveis (7.8 ± 1.6 anos) participaram de duas condições experimentais, sendo a primeira envolvendo a marcha, enquanto a segunda ocorreu o transporte de mochila provida de rodas, 10% PC. Resultados: As forças de reação do solo não apresentaram diferenças entre as duas condições. Porém, mostrou-se que mochilas com rodas não alteram aplicação de forças para execução da tarefa quando comparadas a marcha sem carga na locomoção. A cinemática do tornozelo, do joelho e da pelve permaneceram inalteradas. Conclusão: O uso de rodas na mochila para o transporte de carga de 10% PC não influenciou no padrão de marcha aplicado durante a marcha no plano.

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CONTEXT: Lasiodiplodan, an exocellular (1→6)-ß-d-glucan of molecular weight >1.4 × 106 Da produced by MMPI strain of Lasiodiplodia theobromae (Pat.) Griffon & Maubl. (Brotyosphaeriaceae) is known to exhibit anti-proliferative activity on breast cancer cells (MCF-7), anticoagulant activity when sulfonylated, and reduction in transaminase activity when administered in rats. OBJECTIVE: The effect of intracerebroventricular (I.C.V) injection of lasiodiplodan on neurotoxicity and behavioural changes induced by d-penicillamine was investigated. MATERIALS AND METHODS: Twenty-four male Wistar rats were initially separated in groups of six and treated with 0.15 µmol/µL of NaCl (Groups Ct and d-Pen) and 0.01 µg/µL of lasiodiplodan (Groups Las and Las + d-Pen). After 15 min, they received 6 µmol/µL of NaCl (Groups Ct and Las) and 2 µmol/µL of d-penicillamine (Groups d-Pen and Las + d-Pen). The animal behavior was observed in an open-field test for 60 min. Twenty-four h later, the animals were sacrificed and histopathological analysis and Thiobarbituric acid reactive substances (TBARS) production measurements were performed. RESULTS: Lasiodiplodan prevented neurotoxicity induced by d-penicillamine significantly reducing the production of TBARS (308%; p < 0.05), and behavioural signs; convulsive and pre-convulsive. No histopathological alterations in the cerebral cortex were observed. DISCUSSION AND CONCLUSION: The reduction of TBARS production and convulsive episodes suggests that the protector effect provided by lasiodiplodan passes thought an antioxidant path, possibly interfering in a cascade of neurochemical events, triggering cell death and convulsive episodes. These results demonstrated that lasiodiplodan can be effective in treating neurotoxicity, and reducing damage triggered by convulsions in neuropathies related to GABAergic system.

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RESUMOIntrodução:A cafeína é atualmente a substância mais consumida no mundo, e associada ao exercício físico, vem trazendo importantes ganhos no desempenho.Objetivo:Investigar efeitos bioquímicos da suple-mentação aguda de cafeína após um exercício de endurance em ratos Wistar.Métodos:Foram utilizados 27 ratos Wistar machos, pesando 357 ± 73 g, distribuídos de forma aleatória em três grupos: 1) Controle (sem suplementação e exercício); 2) Salina (salina + exercício); 3) Cafeína (6 mg/Kg de cafeína + exercício). As suple-mentações foram administradas com antecedência de 50 minutos da natação com duração de 60 minutos. Logo após a natação, os animais foram sacrificados para coleta de sangue e biópsia de tecido hepático e muscular. Foram analisados os níveis de glicose sanguínea, triglicerídeos, lactato sérico e concentrações de glicogênio hepático e muscular. Todos os resultados foram representados como média ± EPM. Para a análise estatística foi usado o teste ANOVA one way, sendo considerada diferença estatística somente para P<0,05.Resultados:O glicogênio muscular e o lactato não diferiram entre os grupos. A cafeína preservou os níveis de glicose sanguínea e glicogênio hepático (P<0,05). A cafeína elevou os níveis de glicerol plasmático em 31,2% (P<0,05) quando comparado ao grupo exercitado sem suplementação.Conclusão:O estudo reporta que o uso da cafeína pré-exercício promove alterações bioquímicas que podem melhorar a eficiência metabólica durante o exercício de endurance.

ABSTRACTIntroduction:Caffeine is presently the most consumed substance in the world and, associated with physical exercise, brings important achievements in performance.Objective:To investigate the biochemical effects of acute caffeine supplementation after endurance exercise in Wistar rats.Methods:Twenty-seven male Wistar rats have been used, weighing 357 ± 73 g, randomly distributed in three groups: 1) Control (without supplementa-tion and exercise), 2) Saline (saline+ exercise), 3) Caffeine (6 mg/kg caffeine + exercise). Supplements have been administered 50 minutes before the 60-minute swimming test. Immediately after swimming, the animals have been sacrificed for blood sampling and biopsy of liver and muscle tissue. The levels of blood glucose, triglycerides, serum lactate and concentrations of glycogen in liver and muscle have been analyzed. All results were expressed as mean ± SEM. The statistical analysis used was the ANOVA one way test, being considered statistically signi-ficant only P<0.05.Results:Muscle glycogen and lactate did not differ between groups. Caffeine has preserved the levels of blood glucose and liver glycogen (P<0.05). Caffeine has elevated the levels of plasma glycerol in 31.2% (P<0.05), when compared to the group exercised without supplementation.Conclusion:The study reports that the use of pre-exercise caffeine promotes biochemical alterations that can improve metabolic efficiency during the endurance exercise.

RESUMENIntroducción:La cafeína es actualmente la sustancia de mayor consumo en el mundo, y combinado con el ejercicio físico, ha traído beneficios importantes en el rendimiento durante el ejercicio.Objetivo:Investigar los efec-tos bioquímicos da la suplementación aguda de cafeína después de un ejercicio de endurance en ratones Wistar.Métodos:Fueron utilizados 27 ratones Wistar machos, con 357 ± 73 g de peso corporal, distribuidos de forma alea-toria en tres grupos: 1) Control (sin suplementación y ejercicio); 2) Salina (salina + ejercicio); 3) Cafeína (6 mg/Kg de cafeína + ejercicio). Las suplementaciones les fueran administradas 50 minutos antes de la natación con duración de 60 minutos. Después de la natación, los animales fueron sacrificados para la extracción de sangre y biopsia de tejido hepático y muscular. Fueron analizados los niveles de glucosa sanguínea, triglicéridos, lactato sérico y concentraciones de glucógeno hepático y muscular. Todos los resultados fueron representados como media ± EPM. Para la análisis estadística se aplicó la prueba ANOVA one way, siendo considerada diferencia estadística sólo para P<0,05.Resultados:Lo glucógeno muscular y el lactato no difirieron entre los grupos. La cafeína preservo los niveles de glucosa sanguínea y glucógeno hepático (P<0,05). La cafeína elevo los niveles de glicerol plasmático en 31,2% (P<0,05) en comparación con el grupo ejercitado sin suplementación.Conclusión:El estudio reporta que el uso de la cafeína antes del ejercicio promueve alteraciones bioquímicas que pueden mejorar la eficiencia metabólica durante el ejercicio de endurance.