RESUMO
Aflatoxins (AF) and fumonisins (FU) are a major problem faced by poultry farmers, leading to huge economic losses. This experiment was conducted to determine the effects of AF (1 mg/kg of feed) and FU (25 mg/kg of feed), singly or in combination, on the lipid metabolism in commercial layers and investigate the efficacy of a commercial binder (2 kg/t of feed) on reducing the toxic effects of these mycotoxins. A total of 168 Hisex Brown layer hens, 37 wk of age, were randomized into a 3 × 2 + 1 factorial arrangement (3 diets with no binder containing AF, FU, and AF+FU; 3 diets with binder containing AF, FU, and AF+FU; and a control diet with no mycotoxins and binders), totaling 7 treatments. The hens contaminated with AF showed the characteristic effects of aflatoxicosis, such as a yellow liver, resulting from the accumulation of liver fat, lower values of plasma very low-density lipoprotein and triglycerides, and higher relative weight of the kidneys and liver. Hepatotoxic and nephrotoxic effects of FU were not observed in this study. On the other hand, the FU caused a reduction in small intestine length and an increase in abdominal fat deposition. The glucan-based binder prevented some of the deleterious effects of these mycotoxins, particularly the effects of AF on hepatic lipid metabolism, kidney relative weight, and FU in the small intestine.
Assuntos
Aflatoxina B1/toxicidade , Aflatoxinas/toxicidade , Galinhas/metabolismo , Fumonisinas/toxicidade , Metabolismo dos Lipídeos/efeitos dos fármacos , Aflatoxina B1/administração & dosagem , Aflatoxinas/administração & dosagem , Ração Animal/análise , Animais , Peso Corporal , Dieta/veterinária , Ingestão de Alimentos , Feminino , Contaminação de Alimentos , Fumonisinas/administração & dosagem , Glucanos/química , OviposiçãoRESUMO
The effects of aflatoxin and fumonisin and their combination on egg production and quality, as well as the efficacy of a mycotoxin adsorbent in reducing or eliminating these effects in commercial layers. A number of 168 layers with initial age of 37 weeks were submitted to an experimental period of 56 days. A completely randomized experimental design in a 3x2+1 factorial arrangement was applied (3 treatments with mycotoxins: aflatoxin (AF), fumonisin (FU), or aflatoxin + fumonisin (AF+FU); 2 treatments with or without adsorbent; and a control group that was fed no mycotoxins, nor adsorbent), totaling 7 treatments with 6 replicated of 4 birds/cage. The dietary inclusion levels were 1ppm AF, 25ppm FU, and 2 kg adsorbent/ton feed. Birds fed AF presented the lowest percentage of lay (p=0.0594). Egg mass was the lowest (p<0.05) in the AF+FU treatment (49.49g). The treatment with AF resulted in higher eggshell thickness and strength (p<0.05) than the FU treatment and the control group. The inclusion of the adsorbent in the AF contaminated feed reduced eggshell strength, which returned to levels similar to those of the control group. The observed changes indicate that aflatoxin is toxic at a concentration of 1ppm, and that the effects of fumonisin were less evident as a function of the low dose applied. The inclusion of the glucan (2kg/ton) effectively reverted some of the toxic effects of aflatoxin and, at lower extension, those of fumonisin, when these mycotoxins were invidually added to commercial layer feeds.(AU)
Assuntos
Animais , Galinhas , Ovos/análise , Dieta , AflatoxinasRESUMO
The effects of aflatoxin and fumonisin and their combination on egg production and quality, as well as the efficacy of a mycotoxin adsorbent in reducing or eliminating these effects in commercial layers. A number of 168 layers with initial age of 37 weeks were submitted to an experimental period of 56 days. A completely randomized experimental design in a 3x2+1 factorial arrangement was applied (3 treatments with mycotoxins: aflatoxin (AF), fumonisin (FU), or aflatoxin + fumonisin (AF+FU); 2 treatments with or without adsorbent; and a control group that was fed no mycotoxins, nor adsorbent), totaling 7 treatments with 6 replicated of 4 birds/cage. The dietary inclusion levels were 1ppm AF, 25ppm FU, and 2 kg adsorbent/ton feed. Birds fed AF presented the lowest percentage of lay (p=0.0594). Egg mass was the lowest (p<0.05) in the AF+FU treatment (49.49g). The treatment with AF resulted in higher eggshell thickness and strength (p<0.05) than the FU treatment and the control group. The inclusion of the adsorbent in the AF contaminated feed reduced eggshell strength, which returned to levels similar to those of the control group. The observed changes indicate that aflatoxin is toxic at a concentration of 1ppm, and that the effects of fumonisin were less evident as a function of the low dose applied. The inclusion of the glucan (2kg/ton) effectively reverted some of the toxic effects of aflatoxin and, at lower extension, those of fumonisin, when these mycotoxins were invidually added to commercial layer feeds.