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Ann Hepatol ; 10(4): 477-81, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21911888

RESUMO

INTRODUCTION: Liver transplantation is a highly effective treatment for end-stage liver disease. However, there is debate over the practice of liver transplantation in older recipients (age ≥ 60 years) given the relative shortage of donor grafts, worse post-transplantation survival, and concern that that older patients may utilize excess resources postoperatively, thus threatening the economic feasibility of the procedure. AIM: To determine if patients ≥ 60 years of age utilize more health resources following liver transplantation compared with younger patients. MATERIAL AND METHODS: Consecutive adult patients who underwent primary liver transplantation (n = 208) at a single center were studied over a 2.5-year period. Data were collected on clinico-demographic characteristics and resource utilization. Descriptive statistics, including means, standard deviations, or frequencies were obtained for baseline variables. Patients were stratified into 2 groups: age ≥ 60 years (n = 51) and < 60 years (n = 157). The Chi-Square Test, Mantel-Haenszel Test, 2-sample test and odds ratios were calculated to ascertain associations between age and resource utilization parameters. Regression analyses were adjusted for model for end-stage liver disease score, location before surgery, diabetes mellitus, donor age, cold ischemia time, albumin, and diagnosis of hepatitis C. RESULTS: Recipients ≥ 60 years of age have similar lengths of hospitalization, re-operative rates, need for consultative services and readmission rates following liver transplantation, but have longer lengths of stay in the intensive care (hazard ratio 1.97, p = 0.03). CONCLUSION: Overall, liver transplant recipients ≥ 60 years of age utilize comparable resources following LT vs. younger recipients. Our findings have implications on cost-containment policies for liver transplantation.


Assuntos
Atenção à Saúde/estatística & dados numéricos , Recursos em Saúde/estatística & dados numéricos , Transplante de Fígado , Adulto , Fatores Etários , Idoso , Distribuição de Qui-Quadrado , Cuidados Críticos/estatística & dados numéricos , Atenção à Saúde/economia , Feminino , Recursos em Saúde/economia , Humanos , Tempo de Internação , Transplante de Fígado/efeitos adversos , Transplante de Fígado/economia , Masculino , Pessoa de Meia-Idade , Razão de Chances , Ontário , Readmissão do Paciente , Encaminhamento e Consulta/estatística & dados numéricos , Análise de Regressão , Reoperação , Medição de Risco , Fatores de Risco , Fatores de Tempo , Resultado do Tratamento
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