RESUMO

A comparative study was carried out in which 66 leprosy patients with ulcers were randomly divided in two groups of 33 patients each: Group A (experimental group) was treated with ketanserin gel (2%) and group B with clioquinol cream and/or Lassar paste during a three month period. At the end of the study, when ulcer sizes in the two groups were compared, the group treated with topical ketanserin showed superior results (p < 0.001 using Kolmogorov-Smirnov's test). We conclude that the drug is useful as coadjuavant treatment for healing ulcers in these patients.

Assuntos

Ketanserina/uso terapêutico , Hanseníase/complicações , Antagonistas da Serotonina/uso terapêutico , Úlcera Cutânea/tratamento farmacológico , Administração Tópica , Adulto , Idoso , Feminino , Humanos , Ketanserina/administração & dosagem , Masculino , Pessoa de Meia-Idade , Antagonistas da Serotonina/administração & dosagem , Resultado do Tratamento