RESUMO
Purpose: To evaluate PBS®MCIMMO cement in the filling of bone defects. Methods: Thirty-six adult male Wistar rats were divided into three groups of twelve individuals each (group 1, group 2 and group 3). In all groups, a bone failure in the femur was induced, 2.0 mm wide and 7.0 mm deep. In group 1, the PBS®MCIMMO cement was applied to the bone defect produced and a titanium implant (CONNECTION®) 1.5 mm thick and 6 mm long was installed. In group 2, only the PBS® CIMMO cement was installed. In group 3, only bone failure was performed. Kruskal Wallis tests were performed to compare the mean area among the three groups. Results: In all comparisons, significance was observed for group 2 (p = 0.00140.0026). Conclusion: The PBS®CIMMO cement induced bone neoformation, and integration between the newly formed bone, cement, and implant was observed.(AU)
Assuntos
Animais , Masculino , Ratos , Osso e Ossos/lesões , Osso e Ossos/cirurgia , Cimentos Ósseos/análise , Titânio , Materiais Biocompatíveis/análise , Implantação Dentária/métodos , Ratos Wistar/cirurgiaRESUMO
PURPOSE: To evaluate PBS®MCIMMO cement in the filling of bone defects. METHODS: Thirty-six adult male Wistar rats were divided into three groups of twelve individuals each (group 1, group 2 and group 3). In all groups, a bone failure in the femur was induced, 2.0 mm wide and 7.0 mm deep. In group 1, the PBS®MCIMMO cement was applied to the bone defect produced and a titanium implant (CONNECTION®) 1.5 mm thick and 6 mm long was installed. In group 2, only the PBS® CIMMO cement was installed. In group 3, only bone failure was performed. Kruskal Wallis tests were performed to compare the mean area among the three groups. RESULTS: In all comparisons, significance was observed for group 2 (p = 0.0014-0.0026). CONCLUSION: The PBS®CIMMO cement induced bone neoformation, and integration between the newly formed bone, cement, and implant was observed.
Assuntos
Materiais Biocompatíveis/administração & dosagem , Cimentos Ósseos , Regeneração Óssea/fisiologia , Substitutos Ósseos/administração & dosagem , Cerâmica , Fêmur/cirurgia , Teste de Materiais , Animais , Estudos Longitudinais , Masculino , Modelos Animais , Estudos Prospectivos , Ratos , Ratos WistarRESUMO
Abstract Purpose To evaluate PBS®MCIMMO cement in the filling of bone defects. Methods Thirty-six adult male Wistar rats were divided into three groups of twelve individuals each (group 1, group 2 and group 3). In all groups, a bone failure in the femur was induced, 2.0 mm wide and 7.0 mm deep. In group 1, the PBS®MCIMMO cement was applied to the bone defect produced and a titanium implant (CONNECTION®) 1.5 mm thick and 6 mm long was installed. In group 2, only the PBS® CIMMO cement was installed. In group 3, only bone failure was performed. Kruskal Wallis tests were performed to compare the mean area among the three groups. Results In all comparisons, significance was observed for group 2 (p = 0.0014-0.0026). Conclusion The PBS®CIMMO cement induced bone neoformation, and integration between the newly formed bone, cement, and implant was observed.
Assuntos
Animais , Masculino , Materiais Biocompatíveis/administração & dosagem , Cimentos Ósseos , Regeneração Óssea/fisiologia , Teste de Materiais , Cerâmica , Substitutos Ósseos/administração & dosagem , Fêmur/cirurgia , Estudos Prospectivos , Estudos Longitudinais , Ratos Wistar , Modelos AnimaisRESUMO
PURPOSE: To compare two suture threads, poliglecaprone 25 and nylon, used as intradermal suture for skin closure in women undergoing their first cesarean section. METHODS: This is a randomized clinical trial. A total of 60 women undergoing their first cesarean section were enrolled and prospectively assessed. They were randomly allocated to group I (n=30), which received an intradermal suture with nylon 4.0 or to group II (n=30), which had an intradermal suture with poliglecaprone 25, 4.0. The main author took standardized photographs of the scar 6 months after the operation. Four independent raters, two senior obstetricians and two senior plastic surgeons (a male and a female physician from each specialty) assessed the photographs.The panelists rated the scar according to Trimbos scale, composed by the subscales hypertrophy, color and width of the scar. RESULTS: At baseline, patients in both groups were similar regarding age and body mass index. Five patients withdraw the study, four from group and one from group II. Scars of patients from group II were significantly less hypertrophic (p=0.001), thinner (p=0.019) and had more acceptable color (p=0.019). CONCLUSION: The intradermal suture with poliglecaprone 25 for skin closure after cesarean incision provides better aesthetic result.
Assuntos
Cesárea/métodos , Cicatriz , Dioxanos/uso terapêutico , Nylons , Poliésteres/uso terapêutico , Técnicas de Sutura , Suturas , Materiais Biocompatíveis , Estética , Feminino , Humanos , Estudos Prospectivos , Valores de Referência , Reprodutibilidade dos Testes , Estatísticas não Paramétricas , Resultado do TratamentoRESUMO
Purpose:To compare two suture threads, poliglecaprone 25 and nylon, used as intradermal suture for skin closure in women undergoing their first cesarean section.Methods:This is a randomized clinical trial. A total of 60 women undergoing their first cesarean section were enrolled and prospectively assessed. They were randomly allocated to group I (n=30), which received an intradermal suture with nylon 4.0 or to group II (n=30), which had an intradermal suture with poliglecaprone 25, 4.0. The main author took standardized photographs of the scar 6 months after the operation. Four independent raters, two senior obstetricians and two senior plastic surgeons (a male and a female physician from each specialty) assessed the photographs.The panelists rated the scar according to Trimbos scale, composed by the subscales hypertrophy, color and width of the scar.Results:At baseline, patients in both groups were similar regarding age and body mass index. Five patients withdraw the study, four from group and one from group II. Scars of patients from group II were significantly less hypertrophic (p=0.001), thinner (p=0.019) and had more acceptable color (p=0.019).Conclusion:The intradermal suture with poliglecaprone 25 for skin closure after cesarean incision provides better aesthetic result.(AU)
RESUMO
Abstract Purpose: To compare two suture threads, poliglecaprone 25 and nylon, used as intradermal suture for skin closure in women undergoing their first cesarean section. Methods: This is a randomized clinical trial. A total of 60 women undergoing their first cesarean section were enrolled and prospectively assessed. They were randomly allocated to group I (n=30), which received an intradermal suture with nylon 4.0 or to group II (n=30), which had an intradermal suture with poliglecaprone 25, 4.0. The main author took standardized photographs of the scar 6 months after the operation. Four independent raters, two senior obstetricians and two senior plastic surgeons (a male and a female physician from each specialty) assessed the photographs.The panelists rated the scar according to Trimbos scale, composed by the subscales hypertrophy, color and width of the scar. Results: At baseline, patients in both groups were similar regarding age and body mass index. Five patients withdraw the study, four from group and one from group II. Scars of patients from group II were significantly less hypertrophic (p=0.001), thinner (p=0.019) and had more acceptable color (p=0.019). Conclusion: The intradermal suture with poliglecaprone 25 for skin closure after cesarean incision provides better aesthetic result.
Assuntos
Humanos , Feminino , Poliésteres/uso terapêutico , Suturas , Cesárea/métodos , Técnicas de Sutura , Cicatriz , Dioxanos/uso terapêutico , Nylons , Valores de Referência , Materiais Biocompatíveis , Estudos Prospectivos , Reprodutibilidade dos Testes , Resultado do Tratamento , Estatísticas não Paramétricas , EstéticaRESUMO
BACKGROUND: Venous ulcers are common complications of chronic venous insufficiency that result in severe physical and mental suffering to patients. The oral administration of diosmin/hesperidin has been used as adjuvant therapy in the treatment of chronic venous insufficiency. The purpose of this study was to evaluate and compare the effect of pycnogenol and diosmin/hesperidin on the healing of venous ulcers. METHODS: This longitudinal, prospective, randomized clinical trial was conducted with 30 adult patients with venous ulcers from a vascular surgery outpatient clinic of a university hospital. The patients were randomly allocated to 2 groups: Group 1 (n = 15) was treated with pycnogenol (50 mg orally, 3 times daily) and Group 2 (n = 15) was treated with diosmin/hesperidin (450/50 mg orally, twice daily). They were assessed every 15 days for 90 days. During follow-up visits, photo-documentation was obtained and the ulcer area and circumference of the affected limb were measured. Friedman's test and Mann-Whitney test were used to compare ulcer areas and circumference of affected limbs between and within groups at different time points. The level of significance was set at 5% (P < 0.05) for all tests. RESULTS: Both the pycnogenol and diosmin/hesperidin treatments had a similar effect on the healing of venous ulcers and led to a significant decrease in the circumference of affected limbs (P < 0.0001). CONCLUSION: The results suggest that pycnogenol has an adjuvant effect on the healing of venous ulcers, similar to diosmin/hesperidin.
Assuntos
Diosmina/uso terapêutico , Flavonoides/uso terapêutico , Hesperidina/uso terapêutico , Úlcera Varicosa/tratamento farmacológico , Cicatrização/efeitos dos fármacos , Administração Oral , Idoso , Brasil , Diosmina/administração & dosagem , Diosmina/efeitos adversos , Esquema de Medicação , Combinação de Medicamentos , Feminino , Flavonoides/administração & dosagem , Flavonoides/efeitos adversos , Hesperidina/administração & dosagem , Hesperidina/efeitos adversos , Humanos , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Extratos Vegetais , Estudos Prospectivos , Fatores de Tempo , Resultado do Tratamento , Úlcera Varicosa/diagnósticoRESUMO
PURPOSE: To evaluate the clinical applicability of Pozzolana Biologic Silva cement (PBS(r)) in endodontic surgery. METHODS: Persistent apical periodontitis was diagnosed in 30 teeth of 12 patients by cone-beam computed tomography (CT). All patients had 2 or 4 affected teeth and underwent endodontic surgery with root-end filling. Patients with 2 affected teeth had one tooth (control) treated with mineral trioxide aggregate (MTA-Angelus(r)) as a root-end filling material, and the other tooth treated with PBS (experiment). When the patient had four affected teeth, two of them were treated with MTA and two with PBS. Six months after surgery, all patients were assessed by CT scan. Between-group comparisons of measurements were performed using the Wilcoxon test. RESULTS: Periradicular tissue regeneration was observed in all cases. Significant within-group differences in long axes of the lesion were found in the bucco-palatal direction (PBS group, p=0.0012; MTA group, p=0.024) and coronal-apical direction (PBS group, p=0.0007; MTA group, p=0.0015) between pre- and postoperative measurements. CONCLUSIONS: Pozzolana Biologic Silva cement can be used in the treatment of persistent periradicular lesions. The clinical use of PBS as a root-end filling material may be an alternative to MTA. PBS has additives, which provide enhanced strength.
Assuntos
Compostos de Alumínio/uso terapêutico , Materiais Biocompatíveis/uso terapêutico , Compostos de Cálcio/uso terapêutico , Cimentos Dentários/uso terapêutico , Óxidos/uso terapêutico , Periodontite Periapical/cirurgia , Materiais Restauradores do Canal Radicular/uso terapêutico , Silicatos/uso terapêutico , Adolescente , Adulto , Apicectomia/métodos , Tomografia Computadorizada de Feixe Cônico , Combinação de Medicamentos , Humanos , Pessoa de Meia-Idade , Periodontite Periapical/diagnóstico por imagem , Período Pós-Operatório , Estudos Prospectivos , Regeneração/fisiologia , Raiz Dentária/diagnóstico por imagem , Raiz Dentária/cirurgia , Adulto JovemRESUMO
PURPOSE:To evaluate the clinical applicability of Pozzolana Biologic Silva cement (PBS(r)) in endodontic surgery.METHODS:Persistent apical periodontitis was diagnosed in 30 teeth of 12 patients by cone-beam computed tomography (CT). All patients had 2 or 4 affected teeth and underwent endodontic surgery with root-end filling. Patients with 2 affected teeth had one tooth (control) treated with mineral trioxide aggregate (MTA-Angelus(r)) as a root-end filling material, and the other tooth treated with PBS (experiment). When the patient had four affected teeth, two of them were treated with MTA and two with PBS. Six months after surgery, all patients were assessed by CT scan. Between-group comparisons of measurements were performed using the Wilcoxon test.RESULTS:Periradicular tissue regeneration was observed in all cases. Significant within-group differences in long axes of the lesion were found in the bucco-palatal direction (PBS group, p=0.0012; MTA group, p=0.024) and coronal-apical direction (PBS group, p=0.0007; MTA group, p=0.0015) between pre- and postoperative measurements.CONCLUSIONS:Pozzolana Biologic Silva cement can be used in the treatment of persistent periradicular lesions. The clinical use of PBS as a root-end filling material may be an alternative to MTA. PBS has additives, which provide enhanced strength.(AU)
RESUMO
ABSTRACT PURPOSE: To evaluate the clinical applicability of Pozzolana Biologic Silva cement (PBS(r)) in endodontic surgery. METHODS: Persistent apical periodontitis was diagnosed in 30 teeth of 12 patients by cone-beam computed tomography (CT). All patients had 2 or 4 affected teeth and underwent endodontic surgery with root-end filling. Patients with 2 affected teeth had one tooth (control) treated with mineral trioxide aggregate (MTA-Angelus(r)) as a root-end filling material, and the other tooth treated with PBS (experiment). When the patient had four affected teeth, two of them were treated with MTA and two with PBS. Six months after surgery, all patients were assessed by CT scan. Between-group comparisons of measurements were performed using the Wilcoxon test. RESULTS: Periradicular tissue regeneration was observed in all cases. Significant within-group differences in long axes of the lesion were found in the bucco-palatal direction (PBS group, p=0.0012; MTA group, p=0.024) and coronal-apical direction (PBS group, p=0.0007; MTA group, p=0.0015) between pre- and postoperative measurements. CONCLUSIONS: Pozzolana Biologic Silva cement can be used in the treatment of persistent periradicular lesions. The clinical use of PBS as a root-end filling material may be an alternative to MTA. PBS has additives, which provide enhanced strength.
Assuntos
Humanos , Adolescente , Adulto , Pessoa de Meia-Idade , Adulto Jovem , Óxidos/uso terapêutico , Periodontite Periapical/cirurgia , Materiais Biocompatíveis/uso terapêutico , Compostos de Cálcio/uso terapêutico , Compostos de Alumínio/uso terapêutico , Cimentos Dentários/uso terapêutico , Apicectomia/métodos , Periodontite Periapical/diagnóstico por imagem , Período Pós-Operatório , Regeneração/fisiologia , Raiz Dentária/cirurgia , Raiz Dentária/diagnóstico por imagem , Estudos Prospectivos , Combinação de Medicamentos , Tomografia Computadorizada de Feixe CônicoRESUMO
PURPOSE: To assess periradicular lesions clinically and by computed tomography (CT) after endodontic surgery using either Portland cement or mineral trioxide aggregate (MTA) as a root-end filling material. METHODS: Three patients diagnosed with periradicular lesions by cone-beam CT underwent endodontic surgery with root-end filling. Patient A was treated with MTA as the root-end filling material, patient B was treated with Portland cement and patient C had two teeth treated, one with MTA and the other with Portland cement. Six months after surgery, the patients were assessed clinically and by CT scan and the obtained results were compared. RESULTS: Periradicular tissue regeneration was observed in all cases, with no significant differences in bone formation when comparing the use of MTA and Portland cement as root-end filling materials. CONCLUSION: Both mineral trioxide aggregate and Portland cement were successful in the treatment of periradicular lesions.
Assuntos
Compostos de Alumínio/uso terapêutico , Compostos de Cálcio/uso terapêutico , Cimentos Dentários/uso terapêutico , Óxidos/uso terapêutico , Doenças Periapicais/cirurgia , Materiais Restauradores do Canal Radicular/uso terapêutico , Tratamento do Canal Radicular/métodos , Silicatos/uso terapêutico , Raiz Dentária/cirurgia , Adulto , Combinação de Medicamentos , Feminino , Humanos , Masculino , Teste de Materiais , Doenças Periapicais/diagnóstico por imagem , Projetos Piloto , Período Pós-Operatório , Estudos Prospectivos , Reprodutibilidade dos Testes , Fatores de Tempo , Tomografia Computadorizada por Raios X/métodos , Raiz Dentária/diagnóstico por imagem , Resultado do Tratamento , Adulto JovemRESUMO
PURPOSE: To assess periradicular lesions clinically and by computed tomography (CT) after endodontic surgery using either Portland cement or mineral trioxide aggregate (MTA) as a root-end filling material. METHODS: Three patients diagnosed with periradicular lesions by cone-beam CT underwent endodontic surgery with root-end filling. Patient A was treated with MTA as the root-end filling material, patient B was treated with Portland cement and patient C had two teeth treated, one with MTA and the other with Portland cement. Six months after surgery, the patients were assessed clinically and by CT scan and the obtained results were compared. RESULTS: Periradicular tissue regeneration was observed in all cases, with no significant differences in bone formation when comparing the use of MTA and Portland cement as root-end filling materials. CONCLUSION: Both mineral trioxide aggregate and Portland cement were successful in the treatment of periradicular lesions. .
Assuntos
Adulto , Feminino , Humanos , Masculino , Adulto Jovem , Compostos de Alumínio/uso terapêutico , Compostos de Cálcio/uso terapêutico , Cimentos Dentários/uso terapêutico , Óxidos/uso terapêutico , Doenças Periapicais/cirurgia , Materiais Restauradores do Canal Radicular/uso terapêutico , Tratamento do Canal Radicular/métodos , Silicatos/uso terapêutico , Raiz Dentária/cirurgia , Combinação de Medicamentos , Teste de Materiais , Projetos Piloto , Período Pós-Operatório , Estudos Prospectivos , Doenças Periapicais , Reprodutibilidade dos Testes , Fatores de Tempo , Resultado do Tratamento , Tomografia Computadorizada por Raios X/métodos , Raiz DentáriaRESUMO
PURPOSE: To assess periradicular lesions clinically and by computed tomography (CT) after endodontic surgery using either Portland cement or mineral trioxide aggregate (MTA) as a root-end filling material. METHODS: Three patients diagnosed with periradicular lesions by cone-beam CT underwent endodontic surgery with root-end filling. Patient A was treated with MTA as the root-end filling material, patient B was treated with Portland cement and patient C had two teeth treated, one with MTA and the other with Portland cement. Six months after surgery, the patients were assessed clinically and by CT scan and the obtained results were compared. RESULTS: Periradicular tissue regeneration was observed in all cases, with no significant differences in bone formation when comparing the use of MTA and Portland cement as root-end filling materials. CONCLUSION: Both mineral trioxide aggregate and Portland cement were successful in the treatment of periradicular lesions.(AU)
Assuntos
Animais , Cimentos Dentários/análise , Tomografia Computadorizada por Raios XRESUMO
PURPOSE: To evaluate the use of Portland cements with additives as furcation perforation repair materials and assess their biocompatibility. METHODS: The four maxillary and mandibular premolars of ten male mongrel dogs (1-1.5 years old, weighing 10-15 kg) received endodontic treatment (n=80 teeth). The furcations were perforated with a round diamond bur (1016 HL). The perforations involved the dentin, cementum, periodontal ligament, and alveolar bone. A calcium sulfate barrier was placed into the perforated bone to prevent extrusion of obturation material into the periradicular space. The obturation materials MTA (control), white, Type II, and Type V Portland cements were randomly allocated to the teeth. Treated teeth were restored with composite resin. After 120 days, the animals were sacrificed and samples containing the teeth were collected and prepared for histological analysis. RESULTS: There were no significant differences in the amount of newly formed bone between teeth treated with the different obturation materials (p=0.879). CONCLUSION: Biomineralization occurred for all obturation materials tested, suggesting that these materials have similar biocompatibility.
Assuntos
Cimentos Dentários/uso terapêutico , Defeitos da Furca/tratamento farmacológico , Materiais Restauradores do Canal Radicular/uso terapêutico , Obturação do Canal Radicular/métodos , Raiz Dentária/lesões , Compostos de Alumínio/uso terapêutico , Animais , Dente Pré-Molar , Materiais Biocompatíveis/química , Materiais Biocompatíveis/uso terapêutico , Regeneração Óssea , Compostos de Cálcio/uso terapêutico , Sulfato de Cálcio/química , Sulfato de Cálcio/uso terapêutico , Cimentos Dentários/química , Cães , Combinação de Medicamentos , Masculino , Teste de Materiais , Óxidos/uso terapêutico , Materiais Restauradores do Canal Radicular/química , Silicatos/uso terapêutico , Fatores de TempoRESUMO
PURPOSE: To evaluate the use of Portland cements with additives as furcation perforation repair materials and assess their biocompatibility. METHODS: The four maxillary and mandibular premolars of ten male mongrel dogs (1-1.5 years old, weighing 10-15 kg) received endodontic treatment (n=80 teeth). The furcations were perforated with a round diamond bur (1016 HL). The perforations involved the dentin, cementum, periodontal ligament, and alveolar bone. A calcium sulfate barrier was placed into the perforated bone to prevent extrusion of obturation material into the periradicular space. The obturation materials MTA (control), white, Type II, and Type V Portland cements were randomly allocated to the teeth. Treated teeth were restored with composite resin. After 120 days, the animals were sacrificed and samples containing the teeth were collected and prepared for histological analysis. RESULTS: There were no significant differences in the amount of newly formed bone between teeth treated with the different obturation materials (p=0.879). CONCLUSION: Biomineralization occurred for all obturation materials tested, suggesting that these materials have similar biocompatibility.(AU)
OBJETIVO: Avaliar o uso de cimentos Portland aditivados na reparação de perfurações radiculares e a biocompatibilidade destes materiais. MÉTODOS: Oitenta pré-molares, quatro da arcada dentária superior e quatro da arcada inferior de 10 cães machos, sem raça definida, com idade em torno de um a um ano e meio, pesando entre 10 e 15 kg foram submetidos a tratamento endodôntico, sendo realizadas perfurações nas furcas com broca de diamante 1016 HL. A cavidade envolveu dentina e cemento, como também periodonto e o osso alveolar. Na porção óssea da obturação, barreira de sulfato de cálcio foi utilizada evitando extravasamento do cimento para o espaço periodontal. Foi realizada a distribuição randomizada dos cimentos MTA (controle), Portland tipo II, Portland tipo V e Portland branco estrutural nas obturações. Os dentes foram restaurados com resina composta. Após 120 dias realizou-se eutanásia, retirada dos dentes, preparação e análise histológica. RESULTADOS: Entre os cimentos não houve diferença estatística significante quanto à neoformação óssea (p=0,879). CONCLUSÃO: Ocorreu biomineralização com os diferentes cimentos usados no estudo, sugerindo que estes são similares em termos de biocompatibilidade.(AU)
Assuntos
Animais , Cães , Endodontia/métodos , Cimentos Dentários , Materiais Biocompatíveis/uso terapêutico , Cimentos Ósseos , Osso e Ossos/cirurgia , Osso e Ossos/anatomia & histologia , Cães/cirurgia , PeriodontoRESUMO
PURPOSE: To evaluate the use of Portland cements with additives as furcation perforation repair materials and assess their biocompatibility. METHODS: The four maxillary and mandibular premolars of ten male mongrel dogs (1-1.5 years old, weighing 10-15 kg) received endodontic treatment (n=80 teeth). The furcations were perforated with a round diamond bur (1016 HL). The perforations involved the dentin, cementum, periodontal ligament, and alveolar bone. A calcium sulfate barrier was placed into the perforated bone to prevent extrusion of obturation material into the periradicular space. The obturation materials MTA (control), white, Type II, and Type V Portland cements were randomly allocated to the teeth. Treated teeth were restored with composite resin. After 120 days, the animals were sacrificed and samples containing the teeth were collected and prepared for histological analysis. RESULTS: There were no significant differences in the amount of newly formed bone between teeth treated with the different obturation materials (p=0.879). CONCLUSION: Biomineralization occurred for all obturation materials tested, suggesting that these materials have similar biocompatibility.
OBJETIVO: Avaliar o uso de cimentos Portland aditivados na reparação de perfurações radiculares e a biocompatibilidade destes materiais. MÉTODOS: Oitenta pré-molares, quatro da arcada dentária superior e quatro da arcada inferior de 10 cães machos, sem raça definida, com idade em torno de um a um ano e meio, pesando entre 10 e 15 kg foram submetidos a tratamento endodôntico, sendo realizadas perfurações nas furcas com broca de diamante 1016 HL. A cavidade envolveu dentina e cemento, como também periodonto e o osso alveolar. Na porção óssea da obturação, barreira de sulfato de cálcio foi utilizada evitando extravasamento do cimento para o espaço periodontal. Foi realizada a distribuição randomizada dos cimentos MTA (controle), Portland tipo II, Portland tipo V e Portland branco estrutural nas obturações. Os dentes foram restaurados com resina composta. Após 120 dias realizou-se eutanásia, retirada dos dentes, preparação e análise histológica. RESULTADOS: Entre os cimentos não houve diferença estatística significante quanto à neoformação óssea (p=0,879). CONCLUSÃO: Ocorreu biomineralização com os diferentes cimentos usados no estudo, sugerindo que estes são similares em termos de biocompatibilidade.
Assuntos
Animais , Cães , Masculino , Cimentos Dentários/uso terapêutico , Defeitos da Furca/tratamento farmacológico , Materiais Restauradores do Canal Radicular/uso terapêutico , Obturação do Canal Radicular/métodos , Raiz Dentária/lesões , Compostos de Alumínio/uso terapêutico , Dente Pré-Molar , Regeneração Óssea , Materiais Biocompatíveis/química , Materiais Biocompatíveis/uso terapêutico , Compostos de Cálcio/uso terapêutico , Sulfato de Cálcio/química , Sulfato de Cálcio/uso terapêutico , Combinação de Medicamentos , Cimentos Dentários/química , Teste de Materiais , Óxidos/uso terapêutico , Materiais Restauradores do Canal Radicular/química , Silicatos/uso terapêutico , Fatores de TempoRESUMO
PURPOSE: Clinical, radiological and histological evaluation of root perforations treated with mineral trioxide aggregate (MTA) or Portland cements, and calcium sulfate barrier. METHODS: One molar and 11 premolar teeth of a male mongrel dog received endodontic treatment and furcations were perforated with a high-speed round bur and treated with a calcium sulfate barrier. MTA, Portland cement type II (PCII) and type V (PCV), and white Portland cement (WPC) were used as obturation materials. The teeth were restored with composite resin and periapical radiographs were taken. The animal was euthanized 120 days post-surgery for treatment evaluation. RESULTS: Right lower first premolar (MTA), right lower third premolar (PCV), left lower second premolar (MTA), and right lower second premolar (WPC): clinically normal, slightly radio-transparent area on the furcation, little inflammatory infiltrate, and new-bone formation. Left lower third premolar (PCII), right upper first premolar (WPC), right upper third premolar (PCII), and left upper first molar (PCV): clinically normal, radiopaque area on the furcation, and new-bone formation. Right upper second premolar (MTA), left upper second premolar (WPC), left upper third premolar (PCII): presence of furcation lesion, large radiolucent area, and intense inflammatory infiltrate. CONCLUSION: All obturation materials used in this study induced new-bone formation.
Assuntos
Compostos de Alumínio/farmacologia , Materiais Biocompatíveis/farmacologia , Compostos de Cálcio/farmacologia , Sulfato de Cálcio/farmacologia , Cimentos Dentários/farmacologia , Óxidos/farmacologia , Materiais Restauradores do Canal Radicular/farmacologia , Silicatos/farmacologia , Raiz Dentária/lesões , Animais , Materiais Biocompatíveis/efeitos adversos , Cães , Combinação de Medicamentos , Masculino , Modelos Animais , Dente Molar/diagnóstico por imagem , Dente Molar/efeitos dos fármacos , Dente Molar/lesões , Osteogênese/efeitos dos fármacos , Radiografia , Distribuição Aleatória , Raiz Dentária/diagnóstico por imagemRESUMO
PURPOSE: Clinical, radiological and histological evaluation of root perforations treated with mineral trioxide aggregate (MTA) or Portland cements, and calcium sulfate barrier. METHODS: One molar and 11 premolar teeth of a male mongrel dog received endodontic treatment and furcations were perforated with a high-speed round bur and treated with a calcium sulfate barrier. MTA, Portland cement type II (PCII) and type V (PCV), and white Portland cement (WPC) were used as obturation materials. The teeth were restored with composite resin and periapical radiographs were taken. The animal was euthanized 120 days post-surgery for treatment evaluation. RESULTS: Right lower first premolar (MTA), right lower third premolar (PCV), left lower second premolar (MTA), and right lower second premolar (WPC): clinically normal, slightly radio-transparent area on the furcation, little inflammatory infiltrate, and new-bone formation. Left lower third premolar (PCII), right upper first premolar (WPC), right upper third premolar (PCII), and left upper first molar (PCV): clinically normal, radiopaque area on the furcation, and new-bone formation. Right upper second premolar (MTA), left upper second premolar (WPC), left upper third premolar (PCII): presence of furcation lesion, large radiolucent area, and intense inflammatory infiltrate. CONCLUSION: All obturation materials used in this study induced new-bone formation.(AU)
OBJETIVO: Avaliar clínica, radiológica e histologicamente perfurações radiculares tratadas com MTA e cimentos Portland, com barreira de sulfato de cálcio. MÉTODOS: A amostra foi constituída por 11 dentes pré-molares e um molar de cão macho, sem raça definida. Após tratamento endodôntico realizaram-se perfurações nas furcas com broca esférica de alta rotação e barreira de sulfato de cálcio. Foram utiliados os cimentos MTA, Portland tipo II (CPII), Portland tipo V (CPV) e Portland branco estrutural (CPB). Os dentes foram restaurados com resina composta e submetidos a radiografias periapicais. O animal foi confinado por 120 dias e submetido à eutanásia para avaliações. RESULTADOS: Primeiro pré-molar inferior direito (MTA), terceiro pré-molar inferior direito (CPV), segundo pré-molar inferior esquerdo (MTA) e segundo pré-molar inferior direito (CPB): clinicamente normal; leve área radiotransparente na furca; pequeno infiltrado inflamatório e neoformação óssea. Terceiro pré-molar inferior esquerdo (CPII), primeiro pré-molar superior direito (CPB), terceiro pré-molar superior direito (CPII) e primeiro molar superior esquerdo (CPV): clinicamente normal; área radiopaca na furca; neoformação óssea. Segundo pré-molar superior direito (MTA), segundo pré-molar superior esquerdo (CPB) e terceiro pré-molar superior esquerdo (CPII): clinicamente com lesão na furca; intensa área radiolucida; infiltrado inflamatório intenso. CONCLUSÃO: Todos os cimentos induziram a neoformação óssea.(AU)
Assuntos
Animais , Masculino , Cães , Cimentos Dentários/uso terapêutico , Endodontia/métodos , Defeitos da Furca/reabilitação , Materiais Biocompatíveis/administração & dosagem , Defeitos da Furca/veterinária , Sulfato de Cálcio/administração & dosagemRESUMO
JUSTIFICATIVA E OBJETIVOS: O retalho musculocutâneo transverso do reto abdominal (TRAM) permite uma reconstrução completamente autóloga. É um procedimento complexo, de grande porte, exigindo analgesia eficiente. O objetivo deste estudo foi relatar o uso do bloqueio interpleural, associado à anestesia geral, para mastectomia e reconstrução imediata com retalho TRAM.RELATOS DOS CASOS: Foram avaliadas três pacientes com 37, 43 e 49 anos, apresentando neoplasia mamária. A indução anestésica foi realizada com etomidato (0,2 mg.kg-1), alfentanil (30 µg.kg-1) e rocurônio (0,6 mg.kg-1), sendo a manutenção obtida pela administração de isoflurano (0,5vol% a 3,0vol%). No bloqueio interpleural foram administradas ropivacaína a 0,75% (150 mg), morfina (3 mg) e clonidina (3 µg.kg-1), ao nível do EIC5, na linha axilar média, com agulha de Tuohy 17G; as pacientes foram colocadas na posição céfalodeclive (20º) imediatamente antes da realização do bloqueio, permanecendo por aproximadamente 10 minutos. A intensidade da dor pós-operatória foi analisada pela escala analógica verbal, nas primeiras 24 horas. Durante o intraoperatório foi administrado isoflurano em doses superiores a 0,5% e inferiores a 3%. Com a associação das técnicas anestésicas utilizadas, as pacientes se queixaram de dor leve nas primeiras 24 horas após o término do procedimento anestésico-cirúrgico, necessitando somente de anti-inflamatório não hormonal (dipirona).CONCLUSÃO: A técnica do bloqueio interpleural é segura e de fácil realização em cirurgias de mastectomia e reconstrução mamária imediata com retalho TRAM. Reduz o consumo de fármacos utilizados no intraoperatório e a solicitação de analgésicos no pós-operatório imediato.
BACKGROUND AND OBJECTIVES: Transverse rectus abdominis myocutaneous flap allows for a totally autologous reconstruction (TRAM). It is a complex and major procedure requiring efficient analgesia. This study aimed at reporting the use of interpleural block associated to general anesthesia for mastectomy and immediate reconstruction with TRAM flap. CASES REPORTS: Three patients aged 37, 43 and 49 years with breast neoplasia were evaluated. Anesthesia was induced with used for interpleural block at the level of EIC5 on the medium axillary line with 17G Tuohy needle; patients were placed in the head-down position (20º) immediately before the block, remaining for approximately 10 minutes. Postoperative pain intensity was evaluated by the verbal analog scale in the first 24 hours. Isoflurane was administered in the perioperative period in doses above 0.5% and below 3%. With the association of the anesthetic techniques, patients reported mild pain during the first 24 hours after anesthetic-surgical procedure completion, needing only non-steroid anti-inflammatory drugs (dipirone).CONCLUSION: Interpleural block is a safe and easy technique for mastectomy and immediate breast reconstruction with TRAM flap. It decreases perioperative drugs consumption and the request for analgesia in the immediate postoperative period.etomidate (0.2 mg.kg-1), alfentanil (30 µg.kg-1) and rocuronium (0.6 mg.kg-1) and was maintained with isoflurane (0.5vol% to 3.0vol%). 0.75% ropivacaine (150 mg), morphine (3 mg) and clonidine (3 µg.kg-1) were used for interpleural block at the level of EIC5 on the medium axillary line with 17G Tuohy needle; patients were placed in the head-down position (20º) immediately before the block, remaining for approximately 10 minutes. Postoperative pain intensity was evaluated by the verbal analog scale in the first 24 hours. Isoflurane was administered in the perioperative period in doses above 0.5% and below 3%. With the association of the anesthetic techniques, patients reported mild pain during the first 24 hours after anesthetic-surgical procedure completion, needing only non-steroid anti-inflammatory drugs (dipirone).CONCLUSION: Interpleural block is a safe and easy technique for mastectomy and immediate breast reconstruction with TRAM flap. It decreases perioperative drugs consumption and the request for analgesia in the immediate postoperative period.
RESUMO
PURPOSE: Clinical, radiological and histological evaluation of root perforations treated with mineral trioxide aggregate (MTA) or Portland cements, and calcium sulfate barrier. METHODS: One molar and 11 premolar teeth of a male mongrel dog received endodontic treatment and furcations were perforated with a high-speed round bur and treated with a calcium sulfate barrier. MTA, Portland cement type II (PCII) and type V (PCV), and white Portland cement (WPC) were used as obturation materials. The teeth were restored with composite resin and periapical radiographs were taken. The animal was euthanized 120 days post-surgery for treatment evaluation. RESULTS: Right lower first premolar (MTA), right lower third premolar (PCV), left lower second premolar (MTA), and right lower second premolar (WPC): clinically normal, slightly radio-transparent area on the furcation, little inflammatory infiltrate, and new-bone formation. Left lower third premolar (PCII), right upper first premolar (WPC), right upper third premolar (PCII), and left upper first molar (PCV): clinically normal, radiopaque area on the furcation, and new-bone formation. Right upper second premolar (MTA), left upper second premolar (WPC), left upper third premolar (PCII): presence of furcation lesion, large radiolucent area, and intense inflammatory infiltrate. CONCLUSION: All obturation materials used in this study induced new-bone formation.
OBJETIVO: Avaliar clínica, radiológica e histologicamente perfurações radiculares tratadas com MTA e cimentos Portland, com barreira de sulfato de cálcio. MÉTODOS: A amostra foi constituída por 11 dentes pré-molares e um molar de cão macho, sem raça definida. Após tratamento endodôntico realizaram-se perfurações nas furcas com broca esférica de alta rotação e barreira de sulfato de cálcio. Foram utiliados os cimentos MTA, Portland tipo II (CPII), Portland tipo V (CPV) e Portland branco estrutural (CPB). Os dentes foram restaurados com resina composta e submetidos a radiografias periapicais. O animal foi confinado por 120 dias e submetido à eutanásia para avaliações. RESULTADOS: Primeiro pré-molar inferior direito (MTA), terceiro pré-molar inferior direito (CPV), segundo pré-molar inferior esquerdo (MTA) e segundo pré-molar inferior direito (CPB): clinicamente normal; leve área radiotransparente na furca; pequeno infiltrado inflamatório e neoformação óssea. Terceiro pré-molar inferior esquerdo (CPII), primeiro pré-molar superior direito (CPB), terceiro pré-molar superior direito (CPII) e primeiro molar superior esquerdo (CPV): clinicamente normal; área radiopaca na furca; neoformação óssea. Segundo pré-molar superior direito (MTA), segundo pré-molar superior esquerdo (CPB) e terceiro pré-molar superior esquerdo (CPII): clinicamente com lesão na furca; intensa área radiolucida; infiltrado inflamatório intenso. CONCLUSÃO: Todos os cimentos induziram a neoformação óssea.